The invention provides a vidarabine monophosphate freeze-dried powder injection for injection; the vidarabine monophosphate freeze-dried powder injection for injection is prepared by freeze-drying a vidarabine monophosphate drug solution, wherein the pH of the vidarabine monophosphate drug solution is 7.0-7.5, and each 2000 mL of the vidarabine monophosphate drug solution contains 80-120 g of adenosine monophosphate, 12-18 g of mannitol, 4-6 g of tert-butanol, 18-22 g of dextran, 2-3 g of sodium chloride, 10-15 g of arginine, 4-6 g of ethylenediamine tetraacetic acid disodium salt, a proper amount of a pH regulator, and the balance water. A proper auxiliary material is added to the formula, so the appearance shape and porosity of the freeze-dried product can be improved, the surface of theproduct is more smooth, moreover, the drug properties are more stable, and the preservation and transportation of the drug are facilitated. Moreover, the preparation process is simple, the technicalrequirements are not high, and the production cycle is relatively short; the quality of the prepared product is stable and controllable, so as to be good for long-term storage.