The invention discloses a fertilizer specialized for watermelon plantation. The fertilizer comprises, by weight, 30-50 parts of crop straw, 10-20 parts of stevia, 10-20 parts of vegetable and fruit waste, 20-30 parts of animal manure, 20-30 parts of soybean meal, 4-12 parts of microbial fermentation agent, 10-20 parts of chalk, 2-10 parts of choline chloride, 10-20 parts of calcium superphosphate, 6-16 parts of boron fertilizer, 10-20 parts of urea, 10-20 parts of bone powder, and 8-20 parts of ammonium nitrate. The fertilizer can improve the soil, and preserve the fertility and the moisture. The fertilizer has the advantage of having high use rate and more comprehensive nutrition, having longer fertilizing effect, being capable of promoting the watermelon growth and greatly enhancing the watermelon yield, being capable of improving the watermelon quality. The fertilizer not only satisfies the nutrition needed by the fruit growth, but also alleviates the pollution and destruction to the soil caused by long term fertilizing. The harvests acquired through the use of the fertilizer are both green and safe.