9 results about "Chitosan microsphere" patented technology

This invention provides a thiourea-tertiary amine bifunctional chitosan microsphere and its preparation method, belonging to the field of adsorption material technology. Through a stepwise functionalization and sequential crosslinking method, thiourea groups are first introduced onto the chitosan microspheres, followed by the introduction of tertiary amine groups and secondary crosslinking, successfully preparing chitosan microspheres possessing both thiourea and tertiary amine bifunctional groups. The thiourea and tertiary amine groups in the microspheres of this invention exhibit a synergistic adsorption effect on noble metal chloride anions, significantly improving the selective adsorption capacity and adsorption rate for noble metals such as palladium, platinum, and rhodium. Simultaneously, the dense three-dimensional network structure constructed through stepwise crosslinking greatly enhances the chemical stability and mechanical strength of the microspheres under strongly acidic environments, extending their service life. This preparation method is simple, mild, and environmentally friendly. The prepared adsorbent is particularly suitable for the efficient and selective recovery of noble metals from complex acidic wastewater or electronic waste leachates.

This invention belongs to the field of traditional Chinese medicine fermentation technology, specifically involving a high-enzyme-active Liu Shen Qu (a type of fermented medicinal herb) and its fermentation process. The process first processes red beans, bitter almonds, artemisia annua, cocklebur, and polygonum hydropiper into a medicinal porridge, which is then mixed with wheat flour and a specific fermenting agent to form a soft mass. Its innovation lies in the use of a Bacillus subtilis trehalose protective agent complex and Aspergillus oryzae chitosan microspheres. These two fermenting agents are prepared by spray drying encapsulation and ionogel methods, respectively, significantly improving the survival rate and stability of the fermenting microorganisms during processing and storage. The soft mass undergoes two stages of precisely controlled temperature and humidity fermentation, and finally, after shaping and segmented drying, the finished product is obtained. This process effectively solves the problems of low enzyme activity and poor stability in traditional Liu Shen Qu fermentation, resulting in a Liu Shen Qu product with high digestive enzyme activity and stable, uniform quality.

The application discloses a degradable polymer-based bone repair 3D printing composite material and a preparation method and application thereof, and belongs to the technical field of bone repair material preparation.The raw material of the degradable polymer-based bone repair 3D printing composite material comprises a degradable polymer, a compatibilizer and hydroxyapatite and Mg(OH)2 co-loaded chitosan microspheres.The degradable polymer-based bone repair 3D printing composite material has good mechanical properties, biocompatibility, mineralization capacity, antibacterial and anti-inflammatory properties, can be used as a bone repair material, and is used for preparing a bone repair product through 3D printing after being prepared into a bone repair 3D printing wire material through extrusion molding, thereby providing a novel material solution for bone tissue regeneration and repair.The chitosan can adjust macrophage polarization and reduce the expression of inflammatory factors, so that the composite material has anti-inflammatory properties.

The application discloses a preparation method of chitosan microspheres for cell immobilization and drug delivery, and relates to the field of chitosan microsphere preparation. The application carries out deacetylation on chitin through a microwave induction process technology combined with enzymes, carries out heavy metal green chelation on chitosan by using glutamic acid diacetic acid tetrasodium or citric acid, further improves the extraction and removal capacity of the chelating agent on residual metal ions by using a carbonate salt solubilization technology, and separates and hydrolyzes trace amounts of protein and lipids in the crude chitosan by selecting appropriate biological enzymes to obtain refined chitosan. Meanwhile, the refined chitosan is subjected to enzymatic molecular modification by applying transglycosylation or oxidase, and finally, the chitosan microspheres are prepared by using a green and environment-friendly spray drying method. The chitosan microspheres prepared by the application are smooth in shape, uniform in size, have a particle size of 1-250 mu m, and have a shell-core structure. The chitosan immobilized enzyme widens the application of chitosan in the fields of medicine, food and the like.

The present application relates to the technical field of Volvariella volvacea cultivation, and particularly relates to a Volvariella volvacea cultivation substrate and a cultivation method. The preparation raw material of the Volvariella volvacea cultivation substrate comprises the following components in parts by weight: extract / pectin@chitosan microspheres 3-5 parts, modified tannic acid-dextran 5-7 parts, rice straw 30-40 parts, corn cob 10-15 parts, bran 4-6 parts, and corn flour 3-5 parts. The present application utilizes the slow-release effect of the microspheres and the water storage network of the modified tannic acid-dextran to achieve synergistic effect, significantly improves the water retention rate, mycelial growth rate and biological efficiency of the cultivation substrate, and realizes high-yield and high-quality cultivation of Volvariella volvacea.

The application discloses a special slow-release and controlled-release fertilizer for forests and grasses in desert and arid areas, and belongs to the technical field of agricultural fertilizers. The fertilizer solves the problems of too fast nutrient release, insufficient water retention and easy failure of trace elements of traditional slow-release fertilizers in a desert environment. The technical scheme points of the fertilizer are as follows: a three-layer coating structure is adopted, the core layer comprises mixed particles of ammonium biphosphate, potassium nitrate, magnesium sulfate, a trace element compound, amino acid chelated calcium and humic acid; the slow-release layer is a mixed coating of polylactic acid and ethyl cellulose, and the slow-release layer is inlaid with chitosan microspheres containing bacillus subtilis spores; the water-retaining layer comprises a porous adsorption layer formed by cross-linked sodium polyacrylate and diatomite; and the outermost layer is a carbonized rice husk protective layer. The fertilizer realizes slow nutrient release and long-term water retention through the synergistic effect of the core layer for providing nutrients, the slow-release layer for controlling the release rate, the water-retaining layer for adsorbing water and the carbonized rice husk layer for resisting wind erosion, so that the survival rate of forests and grasses is increased to more than 95%, the number of annual fertilization is reduced by 60%, and the fertilizer is especially suitable for cultivation of drought-tolerant plants such as coniferous trees in desert and arid areas.

This invention discloses a high-strength hook and loop fastener and its manufacturing process, belonging to the field of hook and loop fastener technology. It includes a hook side and a loop side. The hook side uses a composite thermoplastic polyester elastomer composed of a blend of polybutylene terephthalate and polyethylene terephthalate as the hook tooth material. By optimizing the injection molding process parameters, it achieves high toughness while forming a strong anchoring structure with the base fabric, which is a blend of polyester fibers and low-melting-point polyester staple fibers. The loop side involves plasma-assisted chitosan microsphere treatment of the loop fibers composed of polyamide, constructing a micro-nano composite texture on its surface, significantly improving its surface friction coefficient and cohesion. This invention, without significantly increasing costs, achieves a significant improvement in the peel strength and shear strength of the hook and loop fastener through the synergistic effect of the hook and loop sides, while also greatly improving its fatigue resistance and extending its service life.

This invention belongs to the field of polymer materials technology, specifically relating to a bio-based flame retardant, its preparation method, and a bio-based flame-retardant TPU material. The bio-based flame retardant comprises a multi-layered self-assembled flame retardant structure with chitosan microspheres as the core, layered with ammonium polyphosphate and chitosan layers. The flame retardant, with chitosan microspheres as the core, forms a multi-layered self-assembled flame retardant structure through the mutual electrostatic interaction between the chitosan microspheres and ammonium polyphosphate. When added to TPU material, it exhibits good compatibility with TPU material, and the resulting bio-based flame-retardant TPU material possesses excellent mechanical and flame-retardant properties.

This invention discloses an AB-type bimicrosphere powder capable of in-situ liquid absorption and self-assembly, as well as its preparation and application. The preparation method includes: preparing photocrosslinkable hydroxypropyl chitosan and photocrosslinkable oxidized sodium alginate, respectively; using microfluidic technology and ultraviolet light curing to obtain chitosan microspheres loaded with polyphenols and antibacterial agents, and sodium alginate microspheres, respectively; and adsorbing Fe2+ onto the sodium alginate microspheres. 2+ Two types of microspheres were freeze-dried into powder and then mixed in a specific ratio to obtain AB-type dual microsphere powder capable of in-situ liquid absorption and self-assembly. This invention utilizes microfluidic shearing and freeze-drying processes, combined with the synergistic effect of borate ester bonds and carbon-carbon double bonds, to simultaneously achieve the construction of a microsphere cross-linking network and the interaction of polyphenols and Fe. 2+ The loading allows the AB-type bimicrosphere powder, which can absorb liquid in situ and self-assemble, to rapidly absorb liquid upon contact with blood or body fluids and then self-assemble in situ through a Schiff base and a metal-polyphenol network, thereby constructing a stable microsphere scaffold.