Iron isomaltum oligosaccharide and preparing method thereof

Abstract

The invention belongs to the saccharide derivative preparation technology field, in particular to an isomaltose oligosaccharide and preparation process. Isomaltose oligosaccharide is a novel stable chelating biological iron, and has the excellent effect of preventing iron-deficiency anemia of a human or livestock. The productive process comprises firstly preparing or choosing activating isomaltose oligosaccharide whose average molecular weight is 1500-2000 to be purified, conducting complex reaction of activating isomaltose oligosaccharide and iron hydroxide under a certain condition, wherein iron hydroxide is formed by the reaction of inorganic ferric salt and alkali before or in the process of the complex reaction, thirdly, purifying complex compound through adopting the methods such as organic solvent deposition, ion exchange, dialysis or hyper-filtration and the like. The product which is prepared by the invention has wider iron content range from 5% to 30% compared with current iron dextran products at home and abroad, and is superior to other product in other aspects such as flowability, viscosity, stability and absorption effect.

Description

Technical field [0001] The invention belongs to the technical field of preparation of carbohydrate derivatives, in particular to a kind of isomalto-oligosaccharide iron and a preparation method thereof. Background technique [0002] Iron deficiency anemia is not only a common disease in humans, it is also common in the animal kingdom, especially in livestock. For example, almost 95% of piglets have varying degrees of anemia. This is because the amount of iron that the piglet can obtain from breast milk and feed is less than 10% of its physiological requirement. This leads to growth retardation, weight loss, and increased disease incidence and mortality. It is scientifically proven that the above-mentioned situation can be completely improved by injecting a one-time high-quality iron dextran into newborn piglets. Therefore, most developed countries support and encourage people to adopt this scientific method to improve the health of pigs while banning hormone drugs. The quality an...

AI Technical Summary

Problems solved by technology

The disadvantages of this method are: first, it is impossible to produce ultra-low molecular weight products below 3000 industrially; second, the molecular weight distribution range of the product after hydrolysis is wide, and small molecular impurities are difficult to remove; third, this The yield of the method is very low, resulting in high cost

This has just resulted in the quality of the iron dextran produced is not superior enough, and the price is also relatively high, which constitutes some adverse effects in its large-scale promotion, making the further development of this field greatly restricted