5212results about How to "Long duration" patented technology

The present invention relates to new and useful oral tablet compositions which include an immediate release portion having an opioid analgesic and a non-opioid analgesic, providing for a rapid onset of therapeutic effect, and a sustained release portion of an opioid analgesic and a non-opioid analgesic, providing for a relatively longer duration of therapeutic effect. A multilayer oral dosage form containing a sustained release layer, which includes oxycodone and APAP, hydrocodone and APAP, or oxymorphone and APAP, and an immediate release layer containing the same active ingredients as the sustained release layer, is also disclosed. Also disclosed are oral tablet compositions, containing a sustained release core, which includes oxycodone and APAP, hydrocodone and APAP, or oxymorphone and APAP, and an immediate release coating containing the same active ingredients as the sustained release core, are also disclosed. In addition, methods of making and using such oral tablet compositions are disclosed.

The application concerns methods of treatment using anti-ErbB receptor antibody-maytansinoid conjugates, and articles of manufacture suitable for use in such methods. In particular, the invention concerns ErbB receptor-directed cancer therapies, using anri-ErbB receptor antibody-maytansinoid conjugates.

Non-adhesive particles as large as 110 nm can diffuse rapidly in the brain ECS, if coated with hydrophilic coatings such as PEG coatings and preferably having neutral surface charge. The ability to achieve brain penetration with larger particles will significantly improve drug and gene delivery within the CNS since larger particles offer higher drug payload, improved drug loading efficiency, and significantly longer drug release durations.

Haptic sensations for tactile feedback computer interface devices. In one method, a tactile sensation is output during the interaction of a cursor and a graphical object, the tactile sensation being based on a periodic waveform and having a frequency correlated with a size of the graphical object interacted with the cursor. Another method includes receiving an indication of a position of a cursor, causing the cursor to snap to a graphical object, such as a line, when the cursor is within a predetermined distance so that the cursor can be moved along or within the graphical object, and enabling the output of a vibration sensation while the cursor is moved along or within the object. In another method, a tactile sensation includes a pop sensation that is a short, high magnitude sensation, and then a ringing sensation during or immediately after the output of the pop sensation and which can fade in magnitude over time.

An advanced internal combustion-electric hybrid airplane, having at least double the flight range and flight duration than a conventional equivalent airplane, while using the same amount of any desirable fuel. This is achieved by using 2-3× smaller and ultra-lightweight engine for cruising, and ultra-lightweight electric motor powered by lithium batteries during take-off and climbing. The electric motor becomes a generator during cruising and descent, recharging said batteries. The airplane has also temporary silent electric stealth capability and added safety by the electric back-up power. Due to its high efficiency, the operational cost is substantially reduced. Additional features include highly advanced, minimum drag and weight airframe.

A method for machining a transparent material by the non-linear absorption of pulsed laser radiation, in the region of a laser focus, includes the following steps: a laser wavelength of between 300 and 1000 μm is selected; and laser impulses having a temporally flat beam profile are applied. The method is characterized in that the irradiation intensity is selected from an interval pre-determined for the material to be machined, in which plasma is formed without plasma luminescence. An apparatus for laser treating a transparent material includes structure to set an irradiance and inspect the treatment as being within a defined interval.

A method and system detects actions of an object in a scene by first acquiring a video of the scene as a sequence of images, wherein each image includes pixels, wherein the video is partitioned into chunks. The object in the video is tracked. For each object and each chunk of the video, trajectories of the pixels within a bounding box located over the object are tracked, and cropped trajectories and cropped images for one or more images in the chunk are produced using the bounding box. Then, the cropped trajectories and cropped images are passed to a recurrent neural network (RNN) that outputs a relative score for each action of interest.

A system and method for recognizing features for location correction in Simultaneous Localization And Mapping operations, thus facilitating longer duration navigation, is provided. The system may detect features from magnetic, inertial, GPS, light sensors, and / or other sensors that can be associated with a location and recognized when revisited. Feature detection may be implemented on a generally portable tracking system, which may facilitate the use of higher sample rate data for more precise localization of features, improved tracking when network communications are unavailable, and improved ability of the tracking system to act as a smart standalone positioning system to provide rich input to higher level navigation algorithms / systems. The system may detect a transition from structured (such as indoors, in caves, etc.) to unstructured (such as outdoor) environments and from pedestrian motion to travel in a vehicle. The system may include an integrated self-tracking unit that can localize and self-correct such localizations.

Methods and systems are provided for controlling a power transfer rate in to and / or out of a vehicle energy storage device to affect a current state of charge of the energy storage device. The vehicle may be on a mission comprising a plurality of future power transfer opportunities. In one example, the method comprises adjusting the power transfer rate based on an estimated duration of a future power transfer opportunity. Further, the method may include, if the estimated duration of the future power transfer opportunity is different from a predetermined threshold, changing the power transfer rate at the future power transfer opportunity. The method allows the operating life of the energy storage device to be extended.

Frequent application of a virucidal hand lotion containing malic acid, citric acid, and a C1-6 alcohol will prevent the hand-to-hand transmission of rhinoviruses and reduce the incidence of the "common cold" caused by rhinoviruses.

Content delivery is provided responsive to content consumer requests by providing dynamically generated manifests to content consumers, the manifests providing retrieval information to retrieve content or media fragments of content from segments of a broadcast or Webcast and alternative or replacement content. Alternative or replacement content may be targeted, for example selected based in part on characteristics associated with the content consumer. Content fragments may be cached with CDNs, for example based on a defined preference. Actual insertion of alternative content may occur upstream of a content consumer device or at the content consumer device.

The invention relates to an irradiation device and method for the treatment of totally or partially cell-mediated inflammations of the skin, the connective tissue and the viscera, viral and other infectious diseases such as HIV and prionic infections, fungal infections of the skin and the mucous membranes, bacterial diseases of the skin and the mucous membranes as well hand eczema and anal eczema which comprises at least one irradiation device to irradiate a surface treatment area where the wavelength of the emitted radiation to a treatment area is longer than 400 nm and comprises at least one spectral band between 400-500 nm while the radiation device contains means for the generation of optical pulses towards a treatment area with a power density of the optical pulse peaks larger than 0.5 W / cm2 and smaller than 100 kW / cm2. The energy of one pulse relates to 0.05-10 J / cm2.

A LCD display system comprises a LC panel (1), a backlight unit (2) for illuminating the LC panel (1) or a portion thereof, and a controller (3). The controller: (i) controls the LC panel (1) to display a first image (LI) and a second image (RI) forming a stereoscopic pair, (ii) controls the backlight unit (2) to only illuminate the LC panel (1) or the portion thereof during a first period in time (BLON1; T1) after the pixels (10) of the LC panel (1) or the portion thereof have a stable optical state according to the first image (LI), and during a second period in time (BLON2; T2) after the pixels (10) of the LC panel (1) or the portion thereof have a stable optical state according to the second image (RI), and (iii) generates a control signal (CSS) for controlling a first one (40) of a pair of 3D shutter glasses (4) to be in a transmissive state for enabling viewing of the pixels (10) of the LC panel (1) or the portion thereof only during the first period in time (BLON1; T1) and a second one (41) of the pair of 3D shutter glasses (4) to be in a transmissive state for enabling viewing of the pixels (10) of the LC panel (1) or the portion thereof only during the second period in time (BLON2; T2).

A dual-purpose insulated container is disclosed. The container selectively holds a disposable cup such as a take-out coffee cup with a plastic lid containing a beverage or a beverage alone and it is in a double wall construction for insulation generally made of sturdy plastics and elastic materials that are snap coupled to each other in order to enable the consumer to carry the beverage heat protected in two optional modes with one container. Additionally, the container has a handle, which has a built-in plug on a strap. The plug acts to plug the hole that is present on the plastic caps of coffee cups dispensed by retail coffee chains. An auxiliary slide lid may be tightened directly to the container when there is only the beverage to hold. The container has a translucent insulation space that is normally closed but consumer accessible to insert or replace a printed sheet for a visual effect.

The application concerns methods of treatment using anti-ErbB receptor antibody-maytansinoid conjugates, and articles of manufacture suitable for use in such methods. In particular, the invention concerns ErbB receptor-directed cancer therapies, using anri-ErbB receptor antibody-maytansinoid conjugates.

Various aspects of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Aspects of the invention include implantable integrated circuits that have self-referencing and self-clocking signal encoding, and are capable of bidirectional communication. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

Systems and methods for determining an active cam profile from a plurality of cam profiles is disclosed. The systems and methods may be used to determine how to operate an engine torque actuator or provide an indication of cam profile switching degradation.

A method of operating an engine having a hotter and colder airstreams separately controlled to a cylinder is provided. The method controls valve timing during a transition in operating modes to provide improved operation.

A lighting device comprising a first group of solid state light emitters, an element containing luminescent material and a second group of solid state light emitters spaced from the element. In some embodiments, (1) at least 50% of light emitted by one of the first group does not mix with light emitted by the second group before the light emitted by the second group has entered the element, (2) at least 90% of exiting light emitted by the second group travels farther within the lighting device than 90% of exiting light emitted by the first group, (3) an average distance traveled by exiting light emitted by the second group is farther than an average distance traveled by exiting light emitted by the second group, and / or (4) light emitted by the first group directly exiting the lighting device exits the lighting device without being incident upon the element.

An optoelectronic distance measuring device is disclosed. The device has a transmitting unit with a driver stage for emitting optical pulses, a receiving unit for receiving a portion of the optical pulses, said portion being reflected from a target object, and converting it into an electrical reception signal, via a photosensitive electrical component. It also has an analog-digital converter for digitizing the reception signal, and an electronic evaluation unit to ascertain a distance from the target object on the basis of a signal propagation time using the digitized reception signal. The driver stage can be designed so that at least two pulse durations of different length for the optical pulses can be set.

A portable oxygen concentrator includes a pressure swing absorption system defined by a relatively rigid housing adapted to generate a flow of oxygen enriched gas and a battery adapted to provide power to the pressure swing absorption system. The oxygen concentrator has a total weight of less than about 10 lbs, has a maximum flow of 100% O2 equivalent gas of about 0.9 lpm, has a total volume less than about 800 in3, and gas a battery life of at least about 8 hours. The present invention also using a liquefaction or transfill system in combination with such an oxygen concentrator.

The invention discloses a network slice manager and a management method thereof, and belongs to the technical field of communication. The manager comprises a creation module, an expansion module, a deletion module, a user request table, a network slice parameter table, a network slice state table and a plurality of external interfaces, wherein the creation module is respectively connected with the user request table and the network slice parameter table; both the expansion module and the deletion module are respectively connected with the network slice parameter table and the network slice state table; the creation module is connected with a core network, an access network, a physical resource pool and a user by the external interfaces; the expansion module is connected with an existing network slice and the physical resource pool by the external interfaces; and the deletion module is connected with the existing network slice by the external interface. The management method of the manager comprises three parts of creation, expansion and deletion of the network slice. According to the network slice manager and the management method thereof, which are disclosed by the invention, the network slice which meets requirements can be created according to user demands, and a utilization rate of the network slice is effectively maximized, so that a utilization rate of network resources is improved.

Methods and systems are provided for controlling a power transfer rate in to and / or out of a vehicle energy storage device to affect a current state of charge of the energy storage device. The vehicle may be on a mission comprising a plurality of future power transfer opportunities. In one example, the method comprises adjusting the power transfer rate based on an estimated duration of a future power transfer opportunity. Further, the method may include, if the estimated duration of the future power transfer opportunity is different from a predetermined threshold, changing the power transfer rate at the future power transfer opportunity. The method allows the operating life of the energy storage device to be extended.

The invention discloses a lightweight high-performance foam concrete, which is composed of the following components in parts by weight: 50 to 60 parts of cement, 20 to 35 parts of mineral slag, 15 to 20 parts of fly ash, 5 to 10 parts of gypsum, 60 to 80 parts of fine aggregate, 2.7 to 7.3 parts of additive, 0.1 to 0.2 part of fiber, 32 to 45 parts of water, and 5 to 25 parts of foam. The invention also discloses a preparation method of the foam concrete. The foam concrete has the advantages of small volume-weight, high strength, low water absorption, and small contraction rate, and has the waterproof and anti-cracking functions at the same time.

A multi-exercise rotary device, comprising: at least one elongate body-supported member, the body-supported member having a first end adapted to be supported by the body of the user, and a second end opposite the first end, at least one rotating member having a longitudinal axis that is at least semi-rigid, and which axis has a weight-biased distribution toward a distal end thereof; and a rotary mechanism for coupling the rotating member to a point on the body-supported member which is near the second end thereof. The rotary mechanism allows rotational movement of the rotating member about the longitudinal axis of the body-supported member. The rotary mechanism includes a device for constraining the angular movement between the weight-biased longitudinal axis of the rotating member and the longitudinal axis of the body-supported unit to be substantially only in a predetermined plane axially aligned with the body-supported member, and for constraining said plane from twisting with respect to the longitudinal axis of said body-supported member.

A digital image display device for displaying a collection of digital images, comprising: a display screen; a processor; a real-time clock; an image memory for storing a plurality of digital images; and a processor-accessible program memory. The program memory stores executable instructions for causing the processor to execute the steps of: initiating a sequential display of a sequence of digital images on the display screen at an initial time, the sequence of digital images including at least a subset of the stored digital images, each digital image being displayed for an image display duration, the image display duration being set to an initial image display duration at the initial time; and modifying the image display duration during the display of the sequence of digital images.

An apparatus, method and system that uses a Q-switched laser or a Q-seed source for a seed pulse signal having a controlled high-dynamic-range amplitude that avoids and / or compensates for pulse steepening in high-gain optical-fiber and / or optical-rod amplification of optical pulses. Optionally, the optical output is used for LIDAR or illumination purposes (e.g., for image acquisition). In some embodiments, well-controlled pulse shapes are obtained having a wide dynamic range, long duration, and not-too-narrow linewidth. In some embodiments, upon the opening of a Q-switch in an optical cavity having a gain medium, the amplification builds relatively slowly, wherein each round trip through the gain medium increases the amplitude of the optical pulse. Other embodiments use quasi-Q-switch devices or a plurality of amplitude modulators to obtain Q-seed pulses. These configurations provide optical pulses having wide dynamic ranges that ameliorate problems of pulse steepening, non-linear spectral broadening and the like in very-high-power MOPA devices.

The invention belongs to the technical field of the farm chemical, and in particular relates to a plant insecticidal protective agent and an application thereof. The invention provides the plant insecticidal protective agent which is recomposed by food suppressing hydrazine and organic phosphorus (I), pyrethroids insecticides (ii), insect growth regulation agent (III), Macrolides (IV), heterocyclic insecticidal component (V), carbamates (VI) or Nereistoxin pesticide and the application thereof. The recomposed insecticidal composite remarkably improves the insecticidal effect, at least has four acting ways at the same time such as touch out, stomach toxicity, internal absorption and antifeedant so as to adequately protect the plant, favors the delay of the production of the drug resistanceof the insects through different acting ways, and enlarges the pest control spectrum. The composite can be widely applicable to the control of different chewing mouthparts, piercing-sucking mouthparts, lapping mouthparts and rasping mouthparts pests.