Iron-dextrin injection liquid for tonifying qi-blood and used for animals and preparation method

A technology of iron dextran and qi and blood supplementation, applied in the field of medicinal chemistry, can solve problems such as low health rate and survival rate, unfavorable drug absorption, and large stress response of cubs, and achieve long duration, definite curative effect and low side effects. small effect

Inactive Publication Date: 2018-09-07
四川伴农动保生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is: some existing iron supplement injections are not conducive to the body's absorption of drugs after intramuscular injection, and the cubs have a greater st...

Method used

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  • Iron-dextrin injection liquid for tonifying qi-blood and used for animals and preparation method
  • Iron-dextrin injection liquid for tonifying qi-blood and used for animals and preparation method
  • Iron-dextrin injection liquid for tonifying qi-blood and used for animals and preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0035] The invention provides a veterinary iron dextran injection for nourishing Qi and blood:

[0036] First, the specific components of the iron dextran injection are: iron dextran calculated as iron, 5% w / v, Codonopsis pilosula extract, 1% w / v, astragalus polysaccharide, 1% w / v, vitamin B12, 0.003% w / v, Folic Acid, 0.003% w / v, Vitamin E, 1% w / v, Sodium Selenite, 0.05% w / v, Spit 80, 2% w / v, Water for Injection added to full volume.

[0037] Among them, (1) the content of iron dextran is calculated by iron, and the dextran in iron dextran is mixed with dextran with weight average molecular weight of 5000~6000Da, 6000~6500Da and 6500~7500Da, and the weight average molecular weight is 5000~6000Da , 6000~6500Da and 6500~7500Da dextran ratios are 2:5:1 in turn;

[0038] (2) Codonopsis Codonopsis extract is prepared by the following method:

[0039] Step 2-1, take a certain amount of Codonopsis pilosula and put it in a container, add distilled water with a weight part 3 times th...

Embodiment 2

[0051] Based on the iron dextran injection for veterinary qi and blood supplementation provided in Example 1, the difference is that the specific composition ratio of the iron dextran injection is different: iron dextran is calculated as iron, 15% w / v, Codonopsis pilosula extract, 3 %w / v, Astragalus Polysaccharide, 3%w / v, Vitamin B12, 0.008%w / v, Folic Acid, 0.008%w / v, Vitamin E, 3%w / v, Sodium Selenite, 0.1w / v, Spit 80, 5% w / v, add water for injection to the full amount.

Embodiment 3

[0053] Based on the iron dextran injection for veterinary qi and blood supplementation provided in Example 1, the difference is that the specific composition ratio of the iron dextran injection is different: iron dextran is calculated as iron, 12% w / v, Codonopsis pilosula extract, 2 %w / v, Astragalus Polysaccharide, 2%w / v, Vitamin B12, 0.005%w / v, Folic Acid, 0.006%w / v, Vitamin E, 2%w / v, Sodium Selenite, 0.08%w / v , spit pan 80, 3% w / v, add water for injection to the full amount.

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Abstract

The invention discloses iron-dextrin injection liquid for tonifying qi-blood and used for animals. The liquid is prepared from, 5-15% w/v of iron-dextrin by iron, 1-3% w/v of radix codcnopsitis pilosulas extract, 1-3% w/v of astragalus polysaccharides, 0.003-0.008% w/v of vitamin B12, 0.003-0.008% w/v of folic acid, 1-3% w/v of vitamin E, 0.05-0.1% w/v of sodium selenite, 0.2-5% w/v of Twain-80 and the balance injection water; dextran in iron-dextrin is formed by mixing dextran with the weight average molecular weight of 5,000-6,000 Da, 6,000-6,500 Da and 6,500-7,500 Da. A preparation method of the iron-dextrin injection liquid comprises the steps that the set amount of Twain-80, folic acid and vitamin E are added to a container and evenly mixed, and then hot injection water with the amount of 10% of the total amount is added for dissolution; vitamin B12, sodium selenite, radix codcnopsitis pilosulas extract and astragalus polysaccharides are added and stirred and dissolved to obtain amixture; set iron-dextrin is added to the mixture and evenly stirred, and the injection water continues to be added. The iron-dextrin injection liquid has definite treatment effects on pregnant sowsand piglets and is worthy of popularization.

Description

technical field [0001] The invention relates to the field of medicinal chemistry, in particular to an iron dextran injection for veterinary qi and blood supplementation and a preparation method thereof. Background technique [0002] Iron-deficiency anemia during pregnancy is a common phenomenon in sows during pregnancy, which can cause many adverse manifestations and have varying degrees of harm to the health of dams and fetuses. Therefore, iron is very important to maintain the normal growth and development of sow pregnancy and embryo. According to the iron deficiency situation of pregnant sows and piglets, our company uses the traditional theory of iron supplementation of western medicine and the theory of double supplementation of Qi and blood in traditional Chinese medicine that "those with blood deficiency need to replenish Qi first" to improve the traditional blood supplementation scheme of iron dextran, and obtain ideal effect. During pregnancy, a large amount of ir...

Claims

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Application Information

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IPC IPC(8): A61K36/344A61K9/08A61P7/06A61K31/355A61K31/519A61K31/714A61K31/715A61K31/721A61K33/04A61K33/26
CPCA61K9/0019A61K9/08A61K31/355A61K31/519A61K31/714A61K31/715A61K31/721A61K33/04A61K33/26A61K36/344A61K47/26A61P7/06A61K2300/00
Inventor 郭金鹏
Owner 四川伴农动保生物技术有限公司
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