597results about How to "Prevent osteoporosis" patented technology

Benzopyran compounds with strong anti-estrogenic activity and essentially no estrogenic activity are provided, which are OP-1038, which is 3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3R)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-chromen-7-ol, and OP-1074, which is (2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3R)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-chromen-7-ol. OP-1074 is a pure anti-estrogen when tested in the agonist mode and a complete anti-estrogen when tested in the antagonist mode. These compounds are useful for the treatment or prevention of a variety of conditions that are modulated through the estrogen receptor in mammals including humans.

The invention discloses a method for brewing dendrobium nobile wine. Dendrobium nobile is used as one of raw materials, corns and potatoes are used as matrixes, and the dendrobium nobile wine is prepared by the procedures of pretreating, mixing, medicine feeding, primary fermenting, secondary fermenting, squeezing, clarifying, wine decocting, inspecting, bottling and storing. During production, the dendrobium nobile serving as the raw material is subjected to combined hydrolysis by using cellulose and pectinase, so that nutrients beneficial to a human body, contained in the Dendrobium nobile,can be separated out fully; and meanwhile, the corns and the potatoes are used as the matrixes, so that the production cost is reduced and simultaneously the prepared dendrobium nobile wine is red brown, has a unique scorch flavor, is mellow, palatable and slightly bitter and has a long-lasting aftertaste. A product of the dendrobium nobile wine has multiple obvious health-care functions of removing lead, enhancing memory ability and immunity, deferring senility, increasing anoxia resistance, preventing osteoporosis and the like. The method is easy to master and can be applied to scale production.

The present invention provides novel biomaterials comprising one or more of Mg, Zn and F ions in a carbonate-containing biphasic calcium phosphate (BCP) system. The biomaterial may contain Mg, Zn, F, Mg and Zn, Mg and F, Zn and F, or Mg, Zn and F. The biomaterial may be substantially similar in composition to bone mineral (a carbonate apatite). The biomaterial may feature slow release of Mg, Zn, F, Ca, and P ions. The biphasic calcium phosphate, BCP, may be a mixture of unsubstituted hydroxyapatite (HA) and unsubstituted .-TCP, Ca3(PO4)2. BCP of varying HA / .-TCP ratios may be produced by sintering calcium-deficient apatite, for instance having a Ca / P<1.5, 1.6, 1.67, 1.75 or 1.8 that has been prepared either by a precipitation or by a hydrolysis method or by a solid-state reaction. The amount of each component (by weight %) present in the biomaterials may be as follows: Mg 0.5 to 12 wt %, Zn 1 to 12 wt %, F 0.1 to 4 wt %, calcium 20 to 40 wt %, phosphate 10 to 20 wt %, and carbonate (CO3) 1 to 20 wt %. The biomaterial may further comprise one or more other ion such as strontium, manganese, copper, boron or silicate, or one or more other organic moiety such as a protein, a peptide, or a nutraceutical which may provide antioxidant, anti-bacterial or anti-inflammatory properties. The invention also provides methods of inhibiting bone resorption, methods of treating osteoporosis or delaying the onset of osteoporosis, methods of treating a bone fracture, and methods of inhibiting osteoclast activity. Further, the invention provides methods of treating or reversing bone deficiencies such as bone loss, similar to osteoporosis, caused all or in part by a mineral deficient diet, a disease such as cancer or osteopenia, a treatment such as steroid therapy or radiation therapy, or a physical condition such as immobilization.

The invention discloses a weak alkali plant alcohol intoxication-alleviating beverage and a method for preparing the same. The beverage comprises the following components: plant extract, corrective, pH adjusting agent and pure water. The preparation method comprises the following steps that: firstly, the plant extract is decocted and filtered, and the obtained filtrate is cooled down to obtain the plant extract; secondly, the plant extract is mixed with the corrective, and the mixture is dissolved in water; and thirdly the mixed solution is added with proper amount of pH adjusting agent so as to adjust the pH value of the mixed solution to between 6.5 and 8.5, and the mixed solution is subjected to constant volume, filtering, homogenization, sterilization, filling, packaging and checking-up to obtain the weak alkali plant alcohol intoxication-alleviating beverage. The weak alkali plant alcohol intoxication-alleviating beverage has the advantages of removing alcohol toxins, alleviating the alcohol intoxication and protecting the liver, replenishing vital essence and clearing heat, promoting urination and releasing toxin and effectively preventing cardio-cerebral-vascular diseases, osteoporosis, gout, hypertension, high blood fat and the like, along with strong controllability of the production process, good quality reproductivity, fresh and good taste and the suitability for taking at four seasons.

The invention discloses a technology for making coated soybean cheese. The technology for making the coated soybean cheese comprises the following three steps of: A) preparing soybean milk; B) making soybean cheese by mixed fermentation; and C) preparing the coated soybean cheese. The soybean milk is obtained by ultrasonic treatment after soybean is thermally pulped. The soybean cheese is obtained by squeezing soybean curd formed under the co-action of inoculated lactic acid bacteria leaven for fermenting and added D-gluconic acid-delta-lactone (GDL). The coated soybean cheese is prepared by using the soybean cheese subjected to limited enzymolysis as a raw material. The coated soybean cheese which is not added with any milk product components has good flavor property, coated property anddeliquescence in mouth.

The invention discloses coarse cereal food subjected to treatment of germination and a preparation method of the coarse cereal food. The coarse cereal food subjected to treatment of germination consists of the following coarse cereal materials in parts by weight: 100g of millet, 100g of glutinous broom corn, 100g of sorghum, 100g of black soybean, 50g of grain amaranth, 100g of buckwheat, 100g of oat, 100g of black rice, 150g of coix seed, 20g of mung bean, 10g of pea, 20g of red bean, 5g of cowpea and 5g of small lentil. The coarse cereal materials subjected to treatment of germination are purely natural materials and free of toxic and side effects; and the nutritions contained in the materials are activated and easy to be absorbed by the human body and can be used for promoting gastrointestinal peristalsis, helping digestion, increasing appetite and preventing gastrointestinal diseases.

The invention relates to a method for improving quality of frozen freshwater fish surimi. The method comprises the following steps: pretreating a raw material fish, and collecting meat; alternatively bleaching the meat with a sodium carbonate solution and clean water; adding 2.5% of a low sodium salt mixture for blending; adding the following components in percentage by weight in chopping and stirring processes: 60-70% of fish meat, 10-15% of starch, 5-8% of a fishbone enzymatic product, 0.4-0.7% of a composite antifreeze agent, 0.08-0.12% of a composite antibacterial agent, 0.02-0.04% of tea polyphenol, 0.01-0.012% of TBHQ, 0.015-0.02% of L-sodium ascorbate and 10-18% of icy water; subsequently forming; and freezing, thereby obtaining a frozen fish surimi product with improved quality. By adopting the method, not only are the water retention property, oxidation resistance and antibacterial activity of the fish surimi in the machining process improved, but also the nutrient value of the fish surimi can be increased, so that the fish surimi product can be relatively applicable to industrial production and preservation.

The invention discloses fermented coarse cereal food and a preparation method of the fermented coarse cereal food. The fermented food is composed of the following coarse cereal materials in parts by weight: 100g of sorghum, 100g of millet, 100g of buckwheat, 100g of oat, 100g of barley, 100g of black rice, 100g of proso millet, 150g of coix seed, 20g of green bean, 20g of phaseolus angularis, 10g of broad bean, 10g of pea, 5g of cowpea, 100g of black bean and 13g of zymophyte. The coarse cereals adopted by the preparation method provided by the invention are completely pure natural materials, thereby being free from tonic or by effect, lactic acid bacteria is used for guaranteeing delicious and soft taste for the fermented food, and the fermented food can promote gastrointestinal peristalsis, improve digestive ability, add appetite and prevent diseases.

Disclosed are methods for improving bone health, strength and formation in an infant who may be susceptible to developing bone health issues from conception through adolescence. The methods include administration of a nutritional formulation including at least one LCPUFA to a woman during pregnancy and optionally during lactation and breastfeeding of an infant.

A health-care food for increasing human bone density is proportionally prepared from shark cartilage powder, Ca supplement, VD, epimedium, aminoglucose D-hydrochloride, and chondroitin sulfate. Its preparing process is also disclosed.

Disclosed is a antihypelipidemic and antihyperglycemic health food for preventing diseases including cardiovascular disease, diabetes, adjusting internal secretion, resisting osteoporosis and cancer, and beauty treatment. The raw materials include soybean powder 15-30 parts, pumpkin powder 15-30 parts, soybean isoflavones 0.5-1.5 parts, soybean saponin 2-5 parts, astragalus root 10-20 parts, wolfberry fruit 10-15 parts, kudzuvine root 10-15 parts, Chinese yam 10-15 parts, lotus plumule 6-10 parts, Siberian solomonseal rhizome 6-10 parts, cassia seed 6-10 parts, lily 5-8 parts, mulberry leaf 5-8 parts and ginseng 3-5 parts.

The present invention uses (by weight portion) 60-80 portions of collagen protein peptide as main raw material, adds 10-20 portions of protein from soybean, 5.0-15 portions of defatted milk powder, 5.0-15 portions of lactalbumin, 5.0-10 portions of peanut protein and vitamins as auxiliary raw material and through the processes of closed mechanical vibration sorting, placing all the raw material inturn into sterile mixing machine, controlling rotating speed at 20-60 rpm and refining. Said food possesses the functions of supplementing protein for human body and nourishing skin, raising the absorption of mineral elements of calcium, phosphorus and iron, etc. by human body and inhibiting formation of internal free radical, etc.

A fish ball with white color, high toughness and delicious taste is prepared from fresh fish, starch, egg white, lean meat, edible salt, gourmet powder and purified water proportionally through washing fish, taking fish meat, rinsing, dewatering, beating, and heating while shaping.

The invention relates to a soybean whey composite powder and a preparation method thereof. The soybean whey composite powder is obtained through adding soybean lecithin, soybean isoflavone, soybean oligosaccharides and other trace elements to main raw materials comprising non-transgenic soybean protein powder and lactalbumin, and has abundant, comprehensive and balanced nutrition. The composite powder contains a plurality of natural active components, is a high-protein nutritional food, has the advantages of the special fragrance of the soybean proteins, slip mouthfeel, pure and rich taste, instant solving after boiling, and rapid and comprehensive nutrition supplementation, can be rapidly dissolved after slightly stirring in warm boiled water, and has an inherent fragrance and smell, and there is no layering of the soup obtained after dissolving the composite powder in water.

The invention provides a sugar-free high-calcium albumen powder for improving senile osteoporosis, comprising the following components by weight part of 100-160 parts of protein-like substance, 10-30 parts of collagen, 1-10 parts of thickening agent, 1-5 parts of phospholipid, 0.02-0.08 part of sweetening agent, 0.5-1.0 part of calcium salt (by the weight of calcium element), and 0.000002-0.000003 part of vitamin D. The sugar-free high-calcium albumen powder in the invention includes the collagen for achieving the effect of preventing osteoporosis or improving osteoporosis condition in daily food, and includes the vitamin D by compounding so as to be in favour of absorbing calcium salt. The product of the invention is fragrant and smooth, has good taste, aims to solve senile osteoporosis condition, and is extremely suitably used as daily food for the elders.

A sleeve that provides mechanical stimulation to the arm to prevent bone density loss. A primary goal of this product is to prevent bone density loss that occurs during extended space travel. For one embodiment, only the predefined frequency specifications had to be met (between 40 Hz and 60 Hz). By meeting these frequencies for a duration of 30 minutes the product will theoretically prevent the loss of bone density. Additionally, clinical trials will need to be conducted before this product can be marketed. The product includes of several mechanical vibrators attached to a sleeve. The vibrators are small unbalanced-mass motors which are similar to those found in cell phones. The motors are encased in dome shaped housings designed to reduce lateral vibrations along the arm. The product is controlled using an Arduino board attached to the sleeve that actuates the motors. The motors, in turn, provide the specified frequency to the arm for 30 minutes. The spacing of the motor housings was determined from PEA simulations. This resulted in the motors being spaced 2 in apart along the arm at 90° increments around the axis of the arm. The controller has a display that allows for user interaction and includes a session timer. In addition, this product is contemplated for use in reducing muscle atrophy, eliminating bed sores, and treating other ailments that can result from sedentary behavior.

The invention relates to a series of nutrition mixed type cereals taking rice and quinoa as main ingredients, also relates to a preparation method of the nutrition mixed type cereals, and belongs to the technical field of grain processing.The basic nutrition mixed type cereals comprise, by weight, 40-80 parts of rice, 10-30 parts of quinoa, 0.5-2 parts of oats, 0.5-2 parts of buckwheat, 0.5-2 parts of sorghum, 0.5-2 parts of barley, 0.5-2 parts of brown rice, 0.4-2 parts of corn grits, 0.4-1.5 parts of millet, 1-3 parts of soybean and 1-2 parts of compound yam flour.According to requirements of different populations, different nutritional ingredients are mixed and compounded to form the special nutrition mixed type cereals suitable for people preparing for pregnancy, people in pregnancy, people in body shaping and the like.Consumers can cook the various nutrition mixed type cereal in the cooking way of rice during use, nutrition is rich and balanced, and all the various ingredients can be cooked thoroughly together with rice.

The invention relates to the field of medical food and discloses an aquatic collagen peptide food used for adjuvant therapy of osteoporosis and arthritis. Every 100g of the food contains multiple nutritional ingredients as follows: 9-11g of cod skin collagen protein peptide powder, 4-6g of squid skin collagen protein peptide powder, 2-3g of whey protein powder, 2-3g of soybean protein powder, 9-11g of MCT fat, 2-3g of soybean oil, 58-62g of carbohydrate and other vitamins and microelements. The aquatic collagen peptide food takes cod skin collagen protein peptide powder, squid skin collagen protein peptide powder and whey protein powder as main raw materials and has relatively high digestive absorptivity, and collagen protein peptide can promote bone formation and reinforce a bone collagen structure at low calcium level, so that bone strength is improved; bone metabolism can be improved, and ossification can be enhanced; and bone diseases such as the osteoporosis, hyperostosis and swelling and pain of bone joints can be prevented.

The invention relates to application of collagen chelate in the preparation of medicament or food for enhancing bone quality. The medicament or food can enhance bone strength, can enhance bone strength and bone density at the same time and can be used for curing and / or preventing osteoporosis. The collagen chelate is a metalloprotein conjugate; compared with calcium carbonate (CaCO3) with the same calcium concentration, the collagen chelate can enhance the bone density by 4.4 percent and enhance the bone strength by 9.9 percent; and compared with a mixture of collagen and calcium carbonate (CaCO3) with the same concentration of collagen and calcium carbonate, the collagen chelate has a more obvious effect.

A method for the treatment or prevention of osteoporosis in higher mammals is disclosed, the method comprising administering Insulin-like Growth Factor I (IGF-I) in an effective amount thereof to said mammal, said mammal being in need of said treatment or prevention. Compositions for pharmaceutical use in the above method are also described.

The invention discloses bacillus natto capable of producing MK-7 and application of the bacillus natto. The bacillus natto capable of producing MK-7 is named as bacillus natto BLCC1-0053 and preserved in the China Center for Type Culture Collection on January 16th, 2014 with the preservation number of CCTCC M 2014028. The bacillus natto BLCC10053 is capable of producing MK-7, and MK-7 is one active ingredient of frequently-used vitamin K2, can be easily absorbed by a human body, can be used for enhancing bone health, preventing osteoporosis, inhibiting angiosteosis, maintaining arterial elasticity, preventing arteriosclerosis and protecting cardiovascular health. The bacillus natto is capable of producing MK-7, the yield reaches up to 3.68733mg / g, and VK2 required by metabolism of the human body is supplemented, so that the effect of preventing and treating multiple diseases is achieved.

The invention relates to a compound protein powder for preventing postmenopausal women from osteoporosis. The components and weight percentage thereof are: 55 percent to 80 percent of soybean protein powder; 15 percent to 35 percent of whey powder, 0.2 percent to 0.8 percent of soybean isoflavone, 1 percent to 5 percent of oligosaccharide, 1.2 percent to 2.4 percent of calcium lactate, 0.5 percent to 1 percent of stabilizer and 0.5 percent to 1.5 percent of lecithin. The product of the invention is safe and reliable to eat, which has good effect, innocuity, no side effects and dependence. Furthermore, the invention can protect the health of middle-aged women by eating often, especially for improving the healthy problems caused by lacking of estrogen, so as to improve the life quality and living quality of women. Therefore, the invention can be taken as a protein complementary product to be eaten frequently by women.

The present invention is based on sequencing genomic DNA from human chromosome 6 and cDNAs to define the genomic structure of estrogen receptor beta genes and novel polymorphism in the estrogen receptor gene / protein. Such polymorphism can lead to a variety of disorders that are mediated / modulated by a variant estrogen receptor, such as a susceptibility to cancer, osteoporosis, cardiovascular disorder, etc. Based on this sequencing approach, the present invention provides genomic nucleotide sequences, CDNA sequences, amino acid sequences and sequence polymorphism in the ESR-beta genes, methods of detecting these sequences / polymorphism in a sample, methods of determining a risk of having or developing a disorder mediated by a variant estrogen receptor and methods of screening for compounds used to treat disorders mediated by a variant estrogen receptor.

The invention relates to a composition for loosening bowel to relieve constipation. The composition is mainly prepared from the following raw materials in parts by weight of 30-60 parts of roses, 0.5-10 parts of fruits and vegetables, 0.01-16 parts of Chinese herbal medicine materials, 30-60 parts of fructooligosaccharide, 1-5 parts of xylo-oligosaccharides, 0.1-2 parts of maltodextrin, 0-1 part of isomaltooligosaccharide, 0-1 part of polydextrose, 0-1 part of soybean peptides, 0-0.1 part of konjaku powder, 0-0.01 part of vitamin E, and 0-0.1 part of calcium lactate. The composition for loosening bowel to relieve constipation comprises various natural components for moisturizing the intestine, can promote intestinal peristalsis, soften excrement and urine, and improve intestine microenvironment, and achieve the effect of long-acting improving of constipation after being eaten for an appropriate treatment course, and is free from toxic and side effects.

Glycine phosphate (phosphoglycine) and glycine citrate (citroglycine) are used in solubilizing carbonate salts of calcium and optionally zinc in water. Stoichiometric proportions of these ingredients when added to water cause an effervescent reaction that results in an aqueous solution containing completely solubilized and bioavailable calcium phosphate (hydroxyapatite), calcium hydrogen citrate, glycine and optionally, zinc citrate. The aqueous solution of this invention, after addition of suitable flavor(s), sweetener(s), acidulent(s), other nutritional and / or herbal ingredients can be added to the aqueous solvent. The resultant solvent provides a clear aqueous beverage including completely absorbable bone minerals for maintaining bone density and strength and to prevent osteoporosis. The beverage of the present invention can be used as a substitute for plain bottled water, sodas, and the like, and as a substitute for people who are allergic to milk.

The invention discloses tryptophan hydroxylase-1 inhibitor ursolic acid derivatives as well as a preparation method and application thereof and belongs to the technical field of the biological medicine. Proven by experiments, some ursolic acid derivatives are capable of specifically inhibiting the activity of Tph-1 without affecting that of Tph-2, and meanwhile, the bone mineral density data of vertebra also indicate that the bone mineral density of the vertebras of rats is obviously increased, and obviously, the ursolic acid derivatives are capable of effectively preventing osteoporosis and can be widely applied to preparing medicines for treating the osteoporosis.

The invention discloses a seafood soup stock comprising materials of, by weight: 1 to 3 particles of peeled shrimps, 1 to 3g of carrot, 2 to 4g of onion, 2 to 4g of crab meat stick, 1 to 3g of squid, 1.5g of parsley, 1.1g of common salt, 0.2g of a shrimp flavoring, 0.5g of chicken essence, 4g of eggs, 0.05g of pepper, 0.7g of maize starch, 0.8g of a seafood extract, 0.2g of a dried scallop extract, 0.2g of ginger, 0.16g of hydrolyzed vegetable protein, 0.5g of glucose, 0.9g of maltodextrin, and 0.03g of perilla oil. The seafood soup stock provided by the invention is advantaged in balanced nutrition, good color, good flavor, good taste, and food mouthfeel. The soup stock contains various nutrients, and provides positive effects and auxiliary therapeutic effects for human healthy. The alpha-linolenic acid contained in the soup stock is an unsaturated fatty acid assists in reducing blood fat, reducing blood pressure anticoagulation / thrombolysis, improving cardiovascular and cerebrovascular performances, reducing total cholesterol concentration, preventing cardiovascular diseases, inhibiting myocardial infarction and cerebral infarction, and preventing and inhibiting the forming of tumors. The soup stock is rich in trace elements such as calcium, phosphorous, iron, and magnesium. Therefore, the soup provides good heart protecting, hypoglycemic and cancer preventing effects. Also, the soup stock is beneficial for the strength and the hematogenesis functions of skeletons.

The invention discloses coarse cereal-flavored chocolate and its preparation method. The coarse cereal-flavored chocolate is prepared from coarse cereal puffed food, a vegetable oil coating, a chocolate coating and a flavor endowing layer. The invention provides a new composition formula of coarse cereal, the vegetable oil coating, the chocolate coating and the flavor endowing layer, and high dietary fiber of coarse cereal, rich mineral matter, vitamin and functional factor of coarse cereals are fully utilized. The prepared product is rich in nutritional ingredients such as dietary fiber, minerals, high-quality vegetable protein, etc. The formula is novel, mouthfeel is unique, and nutrients are rich. The product is greatly more excellent than snack food on the market. The prepared coarse cereal-flavored chocolate is suitable for oil and young. Though content of fat in the chocolate is high, coating is thin, mass of chocolate is lower than total mass of the product by 10%, and total heat is low relative to dessert such as chocolate, etc.

The invention discloses traditional Chinese medicine composition for treating the osteoporosis, which comprises the following medicine components of herba epimedii, eucommia bark, radix notoginseng, radix astragali, cassia twig, chuanxiong rhizome, rehmannia glutinosa, angelica, drynaria rhizome and dahurian angelica. The traditional Chinese medicine disclosed by the invention has the advantages of simple and reasonable preparation, excellent curative effect, wide medicinal herb resource and no toxic or side effect.

A paper-shaped composite protein-fruit-vegetable food is prepared from collagen polypeptide, soybean protein, albumen, vegetables, fruit, refined konjak starch, carragheenin, chitosan flavouring liquid and water through pretreating, proportional mixing, homogenizing, preparing film flavouring and shaping. Its advantages are rich nutrients including protein, minerals and vitamines, low content of fat, and agreeable taste.