194 results about "Nervonic acid" patented technology

The invention relates to a method for using molecular distillation to extract nervonic acid from acer truncatum buge oil, which obtains the acer truncatum buge oil with acer truncatum buge seeds as raw materials by extracting and pressing; absolute ethyl alcohol or methanol and the acer truncatum buge oil are mixed, then the catalyst is added for reaction, unreacted ethyl alcohol or methanol is removed, glycerine is separated, and fatty acid ester of the acer truncatum buge oil is obtained by rinsing; five-grade molecular distillation is carried out to the fatty acid ester of the acer truncatum buge oil under the condition of different vacuum degrees and temperature so as to obtain the fatty acid ester with the content of nervonic acid ester of more than 80 wt percent; the fatty acid ester is saponated, acid is added to adjust pH value to be 2 to 3, rinsing is carried out so as to lead the fatty acid ester to be neutral, petroleum ether is used for extracting the fatty acid, the petroleum ether is then removed and the product with the content of nervonic acid of more than 80 wt percent is obtained. The invention has the advantages of low operating temperature, simple technique and high content of nervonic acid.

The invention relates to a method for extracting nervonic acid from Acer truncatum Bunge oil, comprising saponifying and low-temperature urea embedding course, normal-temperature vacuum distilling course, low-temperature freezing and step crystallizing course, fatty acid methylesterification and separation course and selectively weak absorbing and purifying course. As compared with the existing techniques, the invention has the following advantages: separating Acer truncatum Bunge oil as raw material to obtain the specially-long unsaturated fatty acid nervonic acid and obtain a series of coarse and fine nervonic acid products of different purities, and the purity of the fine nervonic acid products reaches 99% above. The invention has low processing cost, simple and easy to operate and able to realize industrialized production.

The invention provides an edible blend oil for promoting development of infant brain and nerve cells. The edible blend oil comprises 3-5wt% of algae oil, 3-7wt% of acer truncatum oil, 64-67.5wt% of walnut oil, 8.5-12wt% of linseed oil, 7-9wt% of perilla oil and 7-7.9wt% of pressing peanut oil composition; or the edible blend oil comprises 3-5wt% of algae oil, 3-7wt% of acer truncatum oil, 64-67.5wt% of walnut oil, 8.5-12wt% of linseed oil, 7-9wt% of perilla oil and 7-7.5wt% of sesame oil. The invention solves the problem of serious lack of DHA and nervonic acid in diet for infant and pregnantwoman.

The invention relates to health-caring blend oil rich in alpha-linolenic acid and nervonic acid, as well as a detection method thereof. The health-caring blend oil rich in the alpha-linolenic acid and the nervonic acid comprises the following ingredients in parts by weight: 10-45 parts of linseed oil, 0-15 parts of deep-sea shark oil, 0-10 parts of sorbifolia oil, 5-45 parts of walnut oil, 0-15 parts of tomato seed oil, 0-35 parts of camellia oleifera seed oil, 0-15 parts of olive oil, 3-25 parts of perilla seed oil, and 1-8 parts of black sesame seed oil; and the characteristic fatty acid compositions and the contents thereof are detected by combining HS-SPME-GC-MS. The linseed oil, the deep-sea shark oil, the sorbifolia oil, the camellia oleifera seed oil, the walnut oil, the olive oil, the tomato seed oil, the perilla seed oil and the black sesame seed oil are combined in the blend oil so as to prepare the health-caring blend oil; the ingredients are rationally matched, and health-caring blend oil of different types can be blended according to dietary structures of different populations. The prepared health-caring blend oil is capable of supplementing amino acid, vitamins, minerals and trace elements needed by the human body, as well as keeping nutrition balance; moreover, the blended final products are good in taste, color and luster, and are capable of increasing appetite.

The invention provides an emulsion composition containing nervonic acid, an emulsifier and water, wherein content of water in the emulsion composition is more than 70% in weight ratio, particle size of a fat globule in the emulsion composition is less than 5Mum, weight ratio of the emulsifier to the nervonic acid is 1:(0.1-6), and the emulsifier comprises one or more than one of the following substances: sucrose fatty acid ester, glyceryl monostearate, glycerol distearate, polyglycerol fatty acid ester, sodium stearoyl lactate and sorbitan fatty acid ester. The invention also provides a preparation method of the emulsion composition and application of the emulsion composition in a health product which is orally taken for supplementing the nervonic acid or unsaturated fatty acid and is used for preventing and treating diseases such as cranial nerve degenerative change, disordered brain function and the like.

The invention relates to corn oil, in particular to corn oil containing acer truncatum seed oil. The corn oil containing the acer truncatum seed oil comprises, by weight, 60-90% of corn oil and 40%-10% of acer truncatum seed oil. The content of nervonic acid in the acer truncatum seed oil is larger than 0.5% by weight. The corn oil containing the acer truncatum seed oil has the advantages that the problems the nervonic acid is not contained in existing edible vegetable oil and is lacked in daily diet are solved, the content of the nervonic acid in the corn oil is 0.5%-3.0%, and the nervonic acid has important effects on maintaining nutrition balance of the human body, improving immunity and preventing various diseases; and a blending method of the corn oil containing the acer truncatum seed oil is simple and convenient to operate and reasonable in process, industrial production is easy to achieve, the production cost is low, and the requirements of consumers can be met.

The invention relates to a preparation method. The raw materials in the preparation method are at least refined or purified oil which comprises r-linolenic acid and oil which comprises timnodonic acidand docosahexenoic acid. The raw materials also comprise one or more of acer truncatum seed oil, malania oleifera oil, pine nut oil, coconut oil, palm oil and moringa oleifear seed oil. The preparation method comprises the steps: adding an ester exchange enzyme into the raw materials to react in a closed container; and carrying out distillation, deacidification, deodorization and modified enzymeactivation on the raw material after the ester exchange enzyme reaction to obtain the lipid. One or more fish oil EPA / DHA / DPA r-linolenic acid, C24: 1 nervonic acid, pinolenic acid and the like are combined to one oil molecule to form the lipid containing sn-1-3 site and sn-2 site fatty acids, and meanwhile, the prepared lipid can be combined with other nutritional substances to form novel nutritional food which is suitable for being eaten by pre-operative, rehabilitative and special crowds. The lipid also can be prepared into fructose biscuits, special food hard to swallow and chew and otherfood, so that the individual application direction is wider.

The invention discloses a microalgae strain Mychonases sp. HSO-3-1 and application thereof in the production of biodiesel and nervonic acid with high value. The invention also discloses growth conditions and grease content of the microalgae strain Mychonases sp. HSO-3-1 in different medium components. The microalgae strain Mychonases sp. HSO-3-1 can be used for producing multiple unsaturated fatty acids including linolenic acid C18: 3 and nervonic acid C24:1, with high added value; therefore, byproducts with high added value are obtained while biodiesel is obtained; and an environment-friendly production technology with low cost, which can be used for producing biodiesel and the byproducts with high added value, is supplied.

The invention discloses a nervonic acid composition. A main component of the nervonic acid composition comprises nervonic acid, and an oligosaccharide or beta-glucan; the oligosaccharide is one selected from isomalto oligosaccharide, fructose oligosaccharide or lactose oligosaccharide, xylose oligosaccharide or soybean oligosaccharides. The ingredients above are uniformly mixed so as to obtain a mixture, and the mixture is prepared into tablets, capsules or powder. In addition, natto powder or natto kinases is also added. The nervonic acid composition is capable of promoting neural restoration and brain nourishing effects of nervonic acid; and the oligosaccharide possesses unique biological activity as a functional factor, is capable of preventing tumor and imflammation, and reducing blood fat, and can be used as an immunomodulator. The ingredients are biological response modifiers (BRMs); are healthy food capable of conditioning intestines and stomach functions; possess antibacterial actions; are capable of conditioning intestines and stomach, relaxing bowel, eliminating toxin and beautifying skin; are not influenced by strong acidity of gastric juice; and are capable of realizing colonization in intestinal tract. In addition, nutritional additives and disease-resistant additives with better effects can be obtained via combination of the nervonic acid composition with immune complexes capable of penetrating gastric shield.

The present invention relates to an yuangboafeng (a Chinese medicinal plant) nervonic acid soft capsule and its preparation process, and provides a health-care food with the functions of preventing nerve fibre atrophy, promoting brain development, delaying senility, raising immunity of human body and digestive function. Its preparation method includes the following steps: shelling yuanbaofeng seeds, making crude oil, dewatering and filtering, low-temp. chromatography, separating saturated fatty acid to produce health-care edible oil, finally making said health-care edible oil into the soft capsule. Its nervonic acid content is stable, and its health-care function effect is good.

The invention discloses a drug composition for treating neurasthenia and preventing senile dementia. The drug composition comprises the following raw materials in percentage by mass: 1%-10% of malania oleifera nervonic acid, 1%-10% of helicid, 1%-10% of semen coicis lactone and the balance of auxiliary materials. The drug provided by the invention is helpful for prolonging the sleeping time of old people; the semen coicis lactone is capable of preventing cancers and inhibiting proliferation of various cancer cells; malania oleifera nervonic acid, helicid and semen coicis lactone are combined for effectively preventing and controlling the occurrence of the senile dementia and healing the senile dementia; a safe and effective plant composition extracted from pure plants is provided for the whole world with increasingly severe aging problems. According to the drug composition, the raw materials are reasonable in medicine compatibility and are all from natural plants; meanwhile, a preparation method of the drug composition provided by the invention is strong in operability; especially, an extraction process is involved according to the chemical properties of the effective ingredients of various Chinese herbal medicines, and the effective ingredient content of obtained extract is high; the drug composition has the advantages of high drug effect, low clinical dosage and the like, and the process is stable and suitable for industrial mass production.

The invention discloses a deacidifying and deodorizing refining process of acer truncatum oil. The deacidifying and deodorizing refining process of acer truncatum oil disclosed by the invention comprises the following steps of: (1) degumming; (2) deacidifying; (3) dehydrating and decolouring; and (4) deodorizing. Acer truncatum oil prepared by using the process disclosed by the invention is stored by using a stainless steel tank; the tank is fully filled and sealed after being filled with nitrogen; and the acer truncatum oil is stored at normal temperature. The deacidifying and deodorizing refining process of acer truncatum oil disclosed by the invention is low in cost and easy to operate; the components, such as phospholipid, moisture, protein and the like, are eliminated to the most extent; the beneficial components, such as sterol, nervonic acid and the like, are reserved; and the edible value and the storage value of acer truncatum seed oil are greatly increased.

The invention discloses a soft capsule which is prepared by mixing pterocarya stenoptera oil and walnut oil and a preparation method of the soft capsule. Each capsule comprises the following ingredients in part by weight: 350mg to 400mg of pterocarya stenoptera oil, and 100 to 150mg of walnut oil. The walnut oil and the pterocarya stenoptera oil are extracted through a traditional squeezing method, and compared with the traditional solvent extraction method, the squeezing method has the advantages that no residue of solvent exists, the technique is simple, the color of the oils is clear, and rich ingredients of the composition such as nervonic acid, alpha- linolenic acid and linolic acid are necessary nutrients for the developing and maintaining the brain. The soft capsule has multiple functions of promoting brain development, improving memory power, delaying the aging, resisting the fatigue, lowering the blood fat and the like.

The invention discloses health-care soft capsules prepared by mainly taking extracts of both leaves and seeds of acer truncatum trees as raw materials and a preparation method for the health-care capsules, each capsule comprises the components of, by weight: acer truncatum leaf extract 120-160mg, acer truncatum seed extract 15-30mg, plant oil 280-320mg and vitamin E 10-20mg; The soft capsules are prepared by using both terrestrial plant acer truncatum seeds and terrestrial plant acer truncatum leaves containing respectively rich nerve acid and flavones and have functions of nerve fiber atrophy preventing, brain development promoting, anti-aging, human immunity ability enhancing and digestion promoting.

The invention discloses a health-care lozenge prepared by taking an acer truncatum extract as a major raw material and a preparation method thereof. The health-care lozenge is prepared from the following raw materials in percentage by weight: 20-40 percent of an acer truncatum extract, 15-25 percent of an acer truncatum seed extract, 30-64 percent of a seasoning agent and 1-5 percent of a nutrition fortifier. A tablet is prepared by performing deep processing on terrestrial plant acer truncatum seeds which are rich in nervonic acid and terrestrial plant acer truncatum leaves which are rich in flavone, and has the effects of preventing nerve fiber atrophy, promoting brain development, delaying ageing and enhancing the immunity and digestive function of a human body; and over-high blood fat concentration in blood can be lowered remarkably, and the occurrence probability of diseases such as certain hypertension and cardiovascular and cerebrovascular diseases, blood circulation disorder, and the like is lowered.

In breast milk-imitating milk powder for infant, nervonic acid in 0.05-0.6% is added. Breast milk-imitating milk powder thus obtained can stabilize nergve system, promote brain's development and intelligence growth of infant, and raise the intelligence level of infant.

The invention provides a refining process of acer-truncatum seed oil. The refining process comprises the following steps: degumming, deacidifying, dewatering, decoloring and deodorizing. The refining process provided by the invention has the advantages of low cost, simplicity in operation, convenience, fastness and small pollution. The refining process provided by the invention has the beneficial effects that on the basis of effectively removing bad components such as phospholipid, water and protein in the acer-truncatum seed oil, the other active nutritional components such as sterol, vitamin E and nervonic acid in the acer-truncatum seed oil can be remained to the greatest extent, and the edible value and the storage value of the acer-truncatum seed oil are greatly improved.

The invention relates to a method for producing arachidonic acid oil (AA oil) low in nervonic acid and eicosapentaenoic acid (EPA). The method provided by the invention adopts the mortierella isabelina as the original strain, which undergoes strain activation, preparation of the strain in a shake bottle, and fermentation, then the bacteria are harvested, and the AA oil low in nervonic acid and eicosapentaenoic acid is extracted from the bacterium. With the eicosapentaenoic acid as the original strain for fermentation, the capability of oil production can be improved for 1-3 times, the yield of AA can be raised for 1-3 times; the invention has the simple fermentation condition with controllable process, and capability to produce the mixed oil of AA with high quality which is low in nervonic acid and EPA.

The preparation process of milky nervonic acid tablet includes mixing denatured starch, Acertruncatum Bunge oil connecting nervonic acid, milk powder and glycose via stirring; adding water and vitamin E to form mixed liquid; spray drying to prepare solid oil powder; and finally processing into milk tablet shape. The present invention may be processed into milky tablet or other food form, and the present invention solves the problem of lack of nervonic acid in breast milk substitute and the problem of easy oxidation to degenerate of fatty acid. The food of the present invention can replenish nervonic acid for people of different ages so as to make up brain's nutrients and raise memory.

The invention provides a pharmaceutical composition containing nervonic acid and bamboo leaf flavonoid. The dosage form of the medicine is any pharmaceutically acceptable dosage form of medicines; the bamboo leaf flavonoid also comprises pharmaceutically acceptable salt or solvate; and nervonic acid and bamboo leaf flavonoid are combined at a weight ratio of (0.2-5):1. The preparation method comprises a step of mixing nervonic acid and bamboo leaf flavonoid with a pharmaceutically acceptable medicinal carrier to obtain any pharmaceutically acceptable dosage form of medicines. The invention further provides a collaborative application of the composition in protecting heart and cerebral vessels as well as heart and cerebral tissues, improving heart and cerebral ischemia and the like, and an application in reducing the risk of myocardial infarction, stroke or cardiovascular diseases.

The invention discloses an acer truncatum seed oil nanometer microcapsule for middle-aged and elderly health-care eating, and a preparation method thereof. The preparation method comprises the following steps: by taking acer truncatum seed oil as a core material, octenyl succinic anhydride-modified gum arabic, octenyl succinic anhydride modified starch and oligosaccharide syrup as wall materials, and fatty acid monoglyceride and fatty acid biglyceride as a core material emulsifier, performing dynamic high-pressure microjetting, and spray drying to be powdery to obtain the acer truncatum seed oil nanometer microcapsule product. The prepared acer truncatum seed oil nanometer microcapsule is safe and non-toxic, low in cost, simple in preparation technology, and suitable for large-scale production. Furthermore, the acer truncatum seed oil nanometer microcapsule is rich in nervonic acid and alpha-linolenic acid, thus having the functions of reducing blood fat and blood pressure, inhibiting senile dementia and parkinson's disease, improving sequela of cerebral apoplexy and hypomnesis, prolonging aging and the like. In addition, the acer truncatum seed oil nanometer microcapsule is a nanometer microcapsule product, and the bioavailability of nutritional substances in the acer truncatum seed oil can be effectively improved through the absorption of nanoparticles.

The invention discloses a dual-channel product for preventing and treating encephalopathy. The product comprises nervonic acid and phosphatidylserine according to the mass ratio of being (1-9):(1-9). The preparation method comprises the following steps: (a) compounding according to the mass ratio of raw materials; (b) grinding and degassing; (c) preparing a capsule material; (d) pelleting; (e) molding and drying; (f) pellet washing; (g) selecting and screening; (h) packaging. The invention further discloses an application of the dual-channel product in the preparation of a product for treating a cranial nerve disease. The product can be used for synchronously treating cranial nerve cells and nerve fibers, thereby taking a comprehensive effect on the encephalopathy and having an obvious effect. In addition, the product is natural purely and safe to eat, and can be absorbed completely as well as cannot generate toxic and side effects. The preparation method is reasonable in process and strong in operability, thereby being suitable for large-scale industrial production.

The invention a relates to compound nervonic acid calcium salt and its preparing method and application. Its chemical name is z-15-cis-15-tetracosenic acid calcium salt, and its molecular formula is C48H90O4Ca, and its skeleton symbol is [CH3(CH2)7CH= CH(CH2)13COO]2Ca, its molecular weight is 771.3, and its melting point is 133-135 deg.C. The invention makes nervonic acid directly react with calcium oxide, or nervonic acid directly react with calcium oxide and calcium hydroxide, or nervonic acid directly react with calcium oxide, calcium hydroxide and calcium chloride on certain conditions to make it. It can regulate cranial n's system and functions of brain cells to a certain extent, able to strengthen the connective transfer between brain cells, and improve the action of calcium ions. And it can be singly made into health food or act as a nutrition strengthening agent; also act as health and medicinal raw material, made into tablets, capsules, powder and other health calcium

The invention relates to a natto product capable of dissolving thrombus which has the advantage of fast onset of efficacy, obvious treatment effect, rapid recovery for patients and no bad adverse reaction. The invention is prepared from the following raw materials in parts by weight: 9-45 parts of natto powder, 8-30 parts of propolis, 8-30 parts of bitter gourd, 8-30 parts of ginseng, 8-30 parts of corn stigma, 8-30 parts of ganoderma, 8-30 parts of kappa-selenocarrageenan, 8-30 parts of honeybee pupae, 8-25 parts of royal jelly freezedrying powder, 8-20 parts of rape pollen, 2-10 parts of chitosan, 2-10 parts of the fruit of Chinese wolfberry, 2-10 parts of Chinese gall, 2-10 parts of anemarrhena, 2-10 parts of the root bark of white mulberry, 2-10 parts of root of Chinese trichosanthes, 5-20 parts of nervonic acid, 5-20 parts of cynomorium coccineum and 5-20 parts of desert cistanche.

The invention provides a method for extracting and separating nervonic acid, mainly aiming at solving the problems that the nervonic acid extracted and separated by the existing method is low in purity, and the existing method for extracting and separating the nervonic acid is complicated in process, not easy in realization of industrial production and long in period. The method for extracting and separating the nervonic acid comprises the following steps: (1) extracting; (2) concentrating; (3) carrying out acid regulation; (4) extracting; (5) carrying out ordinary pressure column chromatography. The method is clear and definite in goal; the nervonic acid with content of more than 95% can be stably obtained by the simple and feasible method; furthermore, multiple raw materials containing the nervonic acid can be used for extracting, so that the raw materials are fully utilized, and reasonable development is realized.

The invention relates to a method for distilling and separating a mixture of nervonic acid and erucidic acid from acer truncatum oil molecules. The method comprises the following steps: acer truncatum seeds are subjected to supercritical carbon dioxide extraction method, a leaching method, or a squeezing method to obtain acer truncatum oil; a mixture of anhydrous ethanol and the acer truncatum oil is added with a catalyst and reacts for 1 to 5 hours at a temperature of between 50 and 80 DEG C; a product is separated to obtain glycerol and remove unreacted ethanol to obtain acer truncatum oil ethyl ester; the acer truncatum oil ethyl ester is subjected to molecular distillation under the conditions of controlling vacuum degree and temperature to obtain mixed fatty acid ethyl ester rich in the erucidic acid and the nervonic acid; and the mixed fatty acid ethyl rich in the erucidic acid and the nervonic acid is saponified and is added with acid to adjust the PH value to be neutral, is washed, is subjected to fatty acid extraction through an organic solvent and the organic solvent removal to obtain a product. The method has the advantages of low operation temperature and high utilization rate of resource.

The invention discloses a preparation method of oral liquid of acer truncatum seed oil. The preparation method comprises the following steps: weighing 100-200g of acer truncatum seed oil and 50-150g of a sweetening agent according to the formula for later use; carrying out microcapsule embedding treatment on the acer truncatum seed oil; mixing the acer truncatum seed oil subjected to microcapsule embedding treatment and the sweetening agent; and adding water to quantify at 1L, filling after homogenizing and carrying out sterile packaging to prepare the oral liquid of the acer truncatum seed oil. The oral liquid is high in vitamin and nervonic acid content, suitable for promotion of brain development of the children, improvement of the intelligence level, suppression of alzheimer's disease and parkinson's disease and improvement of sequela of cerebral apoplexy; and the prepared oral liquid is suitable for patients with dysphagia and infants for taking.

The invention discloses a production process for producing Acer trunctum Bunge oil and Acer trunctum Bunge protein powder by using Acer trunctum Bunge seeds as raw materials. Through processes such as cleaning, magnetic separation, husking, low-temperature pressing, low-temperature refining and superfine crushing of the raw materials, i.e., the Acer trunctum Bunge seeds, high-quality Acer trunctum Bunge oil rich in vitamin E and nervonic acid and high-quality Acer trunctum Bunge protein powder can be obtained.

The invention relates to the technical field of medicinal plant ingredient extraction and especially relates to a method for extracting nervonic acid from acer truncatum oil. The method comprises thefollowing steps: removing impurities from crude acer truncatum oil; performing deacidification treatment, performing transesterification on acer truncatum oil and extracting with petroleum ether; taking blended fatty acid; mixing the blended fatty acid with urea and ethyl alcohol in volume concentration of 95%, thereby acquiring a urea-coated mixed solution; refrigerating and freezing; drying under low temperature, thereby acquiring a crude product of nervonic acid; separating by silica gel column chromatography and repeatedly freezing, crystalizing and purifying, thereby acquiring a pure product of nervonic acid. According to the method for extracting nervonic acid from acer truncatum oil provided by the invention, acer truncatum oil is taken as a raw material; the content of nervonic acid in acer truncatum oil is as high as 5.5%; the extraction raw material is extensive in source and low in cost; compared with deep sea shark oil, acer truncatum oil is a new sustainable utilizable nervonic acid resource; the extraction method provided by the invention is simple in operation, high in extraction rate and suitable for industrial production.

The invention provides a nervonic acid composition and application thereof in neuroprotection, and belongs to the field of medicines. By organically compounding nervonic acid, phosphatidylserine, DHA,celery seed oil, Chinese herb extracts and nutrient supplements according to an assistant and guide principle, the nervonic acid composition integrates a nerve cell nutrient, a nerve fiber repair agent, a neurotransmitter activator, a nerve energy security agent and other mechanisms, so that the permeability of a nerve cell membrane is improved by using multiple systems and multiple ways, the release of a neurotransmitter is promoted, the conduction of nerve impulse is accelerated, a nerve information passage is repaired and dredged, and the brain function is activated or reversed. The nervonic acid composition breaks through the limit and the defect of a certain component which is singly applied, and becomes an important product for preventing and treating encephalopathy. Experiments onmore than 3,000 volunteers by trial products prove that the nervonic acid composition has a comprehensive health-care effect on the nervous system, and particularly has a satisfactory effect of preventing and reversing physical disability, language barrier and mental disorder of patients suffering from cerebral apoplexy.