423results about How to "Prevent atrophy" patented technology

The present invention relates to metabolic regulators that affect metabolic function, for example metabolic regulators that affect muscle mass, muscle regeneration, muscle hypertrophy, fat mass, insulin and glucose sensitivity, angiogenesis and cardiovascular function. In particular, the present invention relates to modulating metabolic function by administering an effective amount of a pharmaceutical composition comprising an agent, where the agent activates or inhibits the activity and/or gene expression of the metabolic regulator. The metabolic regulators of the present invention are, for example MSP1 (2160028F08Rik; SEQ ID NO: 16); MSP2 (2310043I08Rik; SEQ ID NO: 17); MSP3 (NM_026754;1 110017116Rik; SEQ ID NO: 1); MSP4 (4732466D17Rik; SEQ BD NO: 18); MSP 5 (NM_024237; 1600015H20Rik; SEQ ID NO: 12); Ins16 (AF_156094; SEQ ID NO: 20). The present invention also provides methods to screen for agents that affect the metabolic regulators of the present invention.

The invention relates to a toothpaste containing coenzyme Q10 and a preparation method thereof, in particular to a composition of toothpastes, belonging to the field of oral healthcare products; based on weight percentage, the coenzyme Q10 in the toothpaste is 1-2% and Chinese herbal extract is 0.5-2%; the rest of accessories are conventional materials for preparing toothpastes. The formulation proportion of the components in the toothpaste is preferably as follows: 2% of coenzyme Q10 mixture, 0.7% of Chinese herbal extract, 35% of abradant, 1.5% of bonding agent, 35% of wetting agent, 0.2% of flavoring agent, 2.5% of foaming agent, 1.5% of essence and 21.6% of deionized water. The toothpaste containing coenzyme Q10 has the healthcare functions the same as the common toothpastes, such as brightening and cleaning the teeth, stopping bleeding of gums and healing oral ulcer; besides, the coenzyme Q10 and Chinese herbal extract permeate the gum cell membrane so that the gum cell obtains energy and tissue vigor is strengthened, thereby essentially conserving the gums, preventing periodontitis, gingivitis and gingival atrophy to reach the aim of strengthening the gums and fixing teeth.

The present disclosure provides a functional electrode stimulation (FES) apparatus for use with prosthetic limbs. FES may provide the benefits of pain management, muscle building, prevention of muscle atrophy, and muscle re-education of residual limb and/or peri-residual limb muscles. The FES apparatus comprises a portable electrical stimulator; means to carry a current between the electrical stimulator and a prosthetic limb liner or socket; a plurality of elastic conductors integrated with the prosthetic limb liner or socket and capable of carrying the current from the means; a plurality of thin planar conductive fabric electrodes capable of carrying the current from the elastic conductors; and a plurality of thin electrodes capable of carrying the current between the thin planar conductive fabric electrodes and the skin of a patient.

The invention discloses a rehabilitation device for preventing atrophy and deformation of hand muscles and application of the rehabilitation device, and belongs to the field of tools for medical rehabilitation. The device comprises a thumb sleeving plate, an index finger sleeving plate, a middle finger sleeving plate, a ring finger sleeving plate and a little finger sleeving plate which correspondto the five fingers of the human body, and are all connected to a fixing plate corresponding to the dorsal of the hands of the human body in shape; all the sleeving plates are of structures corresponding to phalanges of the fingers, and torsion springs are arranged at the corresponding phalangeal joints; the parts, corresponding to the finger tips, of all the sleeving plates are provided with winding idler wheels internally provided with permanent magnet sheets, electromagnetic blocks connected with springs are arranged beside the winding idler wheels, a winding roller is arranged on the fixing plate and uniformly divided into five sections, traction ropes correspondingly connected to the five winding idler wheels are wound around the five sections respectively, and the two ends of each traction rope are wound around the corresponding winding idler wheel and the corresponding winding roller respectively. By means of the rehabilitation device, the fingers can be driven to be completelyclenched, unbent and opened, and comprehensive hand exercise can be achieved.

The invention discloses a neuromuscular electrical stimulation system with implantable automatic feedback adjustment, which can accurately feedback the executive condition of the implanted parameter, improve the therapeutic effects of the implantable electrode specific parameter, really realize improvement and repairing of the individual functions and improve the reliability, effectiveness and controllability of the implanted device. The invention adopts the technical proposal that an implantable electrical stimulation generator are combined with an in vitro controller which can control the stimulus wave parameters and instructions, thereby the online in vivo parameters can be effectively monitored, feedback and adjusted; the signal transmission in the in vitro controller are completed at the same time. The neuromuscular electrical stimulation system can be used in the neuromuscular electrical stimulation field.

An intestinal lengthening device and method for lengthening the intestine of infants and neonates. The method steps include: resecting a section of intestine to be lengthened; closing the one end of the intestine section, preferably the proximal end, and attaching the other end to an opening in the abdominal wall to form a fistula with stoma; allowing the attachments to heal; attaching the intestinal lengthening device; applying and maintaining 5-20 kPa of tension to the device; allowing the gut to rest for 7 days when the desired length is reached; removing the intestinal lengthening device; reattaching the intestinal section to the intestine. The device includes an inserted end that attaches to the mucosal surface of an intestinal section, an abdominal end that attaches to the abdomen of the patient, and a tension rod to incrementally increase the distance between the two ends. An in situ device includes a sealed tension rod between 2 expansion tips.

The invention relates to piglet preweaning feed and a preparation method thereof for solving the problems of bad palatability and low digestibility of the piglet preweaning feed. The technical scheme is that the piglet preweaning feed is a fully expanding particle product and consists of expanding corn, expanding soybean, wheatmeal, dairy products, fish meal, vegetables, an acidulant, water, edible fats, lysine, methionine, vitamin premix and minerals premix. In the method of the invention, the raw materials are mixed and ground, the mixture is stirred, and the obtained product is instantly expanded into the piglet fully expanding particle feed at high temperature under high pressure by a food expander. The product of the invention is totally cured, is soft and crisp and is instantly melt in the mouth or in the water. Compared with the existing practical feed, the feed greatly improves the palatability and the digestibility, has balanced nutrition arrangement, is beneficial for the pig to grow rapidly, solves the problems of low feed intake, slow growth, weight reduction after the piglets are weaned and the like, can prevent intestinal villus atrophy after the piglets are weaned, reduces weaning stress, improves the non-specific immunity capability and guarantees the health of the piglets.

The invention discloses an okra juice drink and a preparation method therefor. The drink comprises the following ingredients, by weight, 45 parts of okra original juice, 4 parts of white granulated sugar, 0.5 part of xylitol, 0.01 part of sucralose, 0.1 part of citric acid, 0.01 part of tartaric acid, 0.03 part of sodium citrate, 0.01 part of glycine, 0.03 part of taurine, 0.03 part of vitamin C, 50.28 parts of purified water for drinking and 0.08-0.1 part of essence. The drink has good taste, and is beneficial for absorption of nutrition and health care components in human body. The bioavailability of active ingredients is raised, and the drink is suitable for popularization and application.

The invention relates to a soft grain feed for a porket. In the invention, according to the technology explanation book editable fat is adopted as additive raw material and added with mineral matters, premix compound of vitamins, dairy products and expansion grains and solid raw materials are crushed into fine powders; then liquid raw materials such as hot water, lard, bean oil, lactic acid and emulsifier are mixed and blended evenly in sequence; the mixed liquid raw materials are added into the solid raw materials by high pressure injection and mixed evenly with the solid raw material; finally the mixed materials are made into grains in the steamless low temperature. The lard and the emulsifier are added as additives and promote softness and crisp and have good taste of the feeds and adapt the feeds to digestion physiological characteristics of the porket; the adding of dairy products not only guarantees high nutritional concentration but also greatly improves appetite and digestion ability of the porket. The feeds of the invention can improve taste of feeds, appetite of the porket, help quick growth of the porket, prevent atrophy of intestinal villi of the porket when ablactation, reduce stress caused by ablactation, improve non-specificity immunity and guarantee health of the porket.

The invention discloses a flexible rehabilitation training glove for stroke patients, which comprises a flexible retractable finger traction component and a driving component, and there are five flexible retractable finger traction components arranged in a hand shape. All flexible retractable finger traction components are connected with the driving component, and are stretched under the drive of the driving component; all flexible retractable finger traction components are provided with finger band and/or finger stall. According to the flexible rehabilitation training glove, stroke patients can carry out rehabilitation training for hands, stimulate the reestablishment of neural pathways, prevent the adhesion of soft tissue, prevent muscle atrophy, and avoid the ossification of hand tissue due to calcification, so as to promote the rehabilitation of stroke.

A cervical collar that allows varying mobility to the cervical region with the range of motion or degree of mobility being adjustable and quantifiable. The customizable collar having adjustable and quantifiable mobility allows not only graduated mobility for the patient and consequently progressive strengthening but still protects the injured or diseased cervical segments. The cervical collar may also provide a user-defined and adjustable distraction force that in the medical setting allows physicians or rehabilitating specialists to adjust, graduate and monitor the amount of distraction force being applied to the cervical column. In a home use setting, patients are able to select a comfortable amount of force to counter the weight of the head. In addition to graduated rotation and/or an adjustable distraction force, a minimalist cervical collar configuration is provided that is less obtrusive, less conspicuous, light weight and can be worn in part under clothing.

The invention relates to the field of intelligent nursing, in particular to an intelligent wheelchair vehicle with a nursing function. The intelligent wheelchair vehicle includes a movable vehicle body, a movable vehicle frame, an electric device, a traveling device, a control device, a toilet device, a power supply, an air supply device and a sun shading device. The movable vehicle body is installed on the movable vehicle frame, the movable vehicle frame is equipped with the electric device, the traveling device, the control device, the toilet device, the power supply and the air supply device, the movable vehicle frame can be transformed into sitting, lying down and turning over states, the toilet device is provided with a toilet, the toilet is connected with a cleaning device and a drying device, the air supply device separately communicates with air bags in the movable vehicle body, and the sun shading device is installed at the upper part of the movable vehicle frame. Compared with the prior art, the intelligent wheelchair vehicle with the nursing function of the invention is used as a vehicle and a bed, has the functions of transferring and turning over, and at the same time,the intelligent toilet is arranged to facilitate users to go to the toilet by themselves, the functions of cleaning, drying and odor prevention also be provided, and the work of nurses is greatly alleviated.

The invention relates to a propolis soft capsule. The propolis soft capsule comprises a rubber sheet and a capsule content, wherein the capsule content comprises the following components in percent by weight: 20%-60% of propolis supercritical CO2 extract, 30%-70% of wheat-germ oil and 1%-10% of vitamin E; components of the rubber sheet are gelatin, glycerol and purified water in a weight ratio of 100:42:100. The propolis soft capsule is integrated with improving effect of propolis on diabetes mellitus and preventing effect of vitamin E on chronic complication of the diabetes mellitus; moreover, the components are good in synergistic effect. The invention also provides a preparation method of the propolis soft capsule.

A myocyte culture pacing apparatus operating in conjunction with a standard culture dish that permits long term maintenance of cultured myocyte cells over a period of several weeks The device includes a base unit for receiving the culture dish, and an electrode unit for placement atop the culture dish which can receive the cover of the culture dish. The electrode unit has a first and a second planar conductive electrodes extending into each well of the culture dish. The electrodes are planar and extend across the width of the well and are connected to electrical connector for connection to an external electronic unit, which supplies the a variety of electrical pulse regimes to pace the myocyte cultures. The electronic unit permits the type, frequency, duration, voltage and the current of the pulses to be varied in accordance with the desired pacing regime.

The invention relates to a pollen pini tooth cleaning agent and a preparation method thereof, and specifically relates to a mouthwash using pollen pini as a main raw material and a preparation method thereof. Main raw materials comprise 30-55 parts of pollen pini, 12-35 parts of chitosan, 10-20 parts of sodium aluminum carbonate, 5-10 parts of zinc chloride and 10-25 parts of pennyroyal. The cleaning agent provided by the invention can be used as a mouthwash for everyday tooth brushing and gargling before and after meals; the cleaning agent can clean teeth and oral cavity, prevent carious tooth, treat gingival bleeding and periodontitis, is convenient for usage and has a lasting effect.

System, device and method for providing neuromuscular electrical stimulation (NMES) to muscles of foot. The device includes an electrical signal generator for producing a wave pattern of variable frequency, duration, intensity, ramp time and on-off cycle. Device further includes surface electrodes for being positioned over the foot muscles or around ankles and attached to signal generator. Signal generator is programmed to stimulate the foot muscles and nerves. Location of the electrodes and the programming are adjusted to reduce pooling of the blood in the soleal veins of the calf and enhance venous blood flow to prevent deep vein thrombosis (DVT), to enhance venous blood flow for the post-thrombotic syndrome patient, to expedite wound healing, to reduce neuropathic pain of the foot and ankle, chronic musculoskeletal pain of the ankle and foot, and acute post-operative foot and ankle pain, and to prevent muscular atrophy of the foot muscles.

The present invention discloses a Chinese medicine for preventing and curing osteoporosis. The share by weight of the effective ingredients is respectively 12-48 shares by weight of malaytea scurfpea, 12-48 shares by weight of epimedium herb,18-48 shares by weight of prepared rehmannia root, 12-48 shares by weight of danshen root and 5-58 shares by weight of oyster. According to different characteristics of each Chinese herbal medicine, the ingredients are made into tablets, capsules, pills and granules by ethanol extraction, hot-water extraction and grinding. Animal experiments and the clinical observation show that the present invention has obvious function of invigorating the kidney and strengthening the bones, and obvious effect of prevention and cure for osteoporosis.

The invention discloses a mixed feature-based fine imaginary action online brain-computer interface method. The method comprises the steps of designing four actions of making a fist, raising the wrists, bending the elbows and abducing the shoulders for different joints of the upper limb on the right side; giving electrical stimulation during prompting of starting through electrodes placed on flexor muscles of the palms, median nerves of the wrists, bicipital muscles of the arms and deltoid muscles, paying selective attention to electrical stimulation positions while imagining the correspondingactions by a testee; effectively fusing event-related desynchronization features of different frequency distribution and electrical stimulation induced steady state somatosensory evoked potential features to form a mixed normal form; by adopting a multi-frequency component spatial filtration-based algorithm, extracting the event-related desynchronization and steady state somatosensory evoked potential features from the mixed normal form, thereby increasing the correct identification rate; and performing mode identification by adopting a multi-classification support vector machine, outputtinga decision value, and feeding back a voice prompt to the testee. The body parts controlled by high-correlation adjacent brain regions can be effectively distinguished; and the method has excellent performance.

The invention discloses a rehabilitation walker for children with cerebral palsy. The rehabilitation walker comprises a length-adjustable bottom frame of which the front is opened in an arch shape andextending from the middle to the rear, universal carrying wheels arranged on the lower portion of the bottom frame, a front vertical rod hinged with the bottom frame, a rear vertical rod fixedly connected with the bottom frame, a linear actuator hinged with the front vertical rod and the rear vertical rod separately, two armrest arms fixedly arranged on the front vertical rod separately and a shock absorber fixedly arranged on the rear vertical rod, wherein the armrest arms are arc-shaped bent elbows, the upper portion of the rear vertical rod is fixedly provided with a crotch supporting seat, and the rear of the crotch supporting seat is fixedly provided with a backrest. The rehabilitation walker for the children with the cerebral palsy has the advantages that the structure is simple, the balance can be kept well, the good balance can be provided for the children with the cerebral palsy so that a patient can complete coordinated movements such as walking upright, walking and weight loss walking, ensure the relative activity of the limbs, enhance the muscle force of the upper and lower limbs and prevent muscle atrophy.

The present invention relates to one kind of oral cavity and tooth cleaning article prepared with musk, cattail pollen, safflower, dahurian angelica root, astragalus root and other 11 kinds of Chinese medicinal materials. It can inhibit exogenous bacteria, inhibit tartar, improve tooth state, regulate microecological balance of periodontium, prevent caries and other dental diseases and relieve toothache.