A lab table top cleaning device comprises a table top and a cabinet body supporting the table top, a brush roller is arranged on one side of the table facing away from the cabinet body, a brush roll is provided with a first bristle, a first bristle is used to clean the table top, gears may be provided on the table top, as the shaft cent of the gear is rotatably connected with the table top, one end of the brush roller is fixedly connected with the outer peripheral surface of the gear wheel, a rotary mechanism is also arranged on the table top, when the rotating mechanism is activated, the gears rotate counterclockwise alternately, the brush roller is centered on the axis of the gear, swing back and forth on the table, the rotating mechanism comprises a passive wheel and a rack which are meshed with each other, the axle center of the passive wheel is rotatably connected with the table top, and the driving wheel is provided with a rotating electric machine for rotating the driving wheel,and the outer peripheral surface of the driving wheel is symmetrically provided with a first tooth portion and a second tooth portion, so that the brush roller swings back and forth on the mesa underthe alternating action of the first tooth portion and the second tooth portion.