The invention belongs to the technical field of electrostatic spinning and relates to a portable handheld electrostatic spinning device. The top of a pushing rod of a medical syringe is provided with a pressure welding switch, a metal foil is arranged on the top side fixedly, a spinning solution is arranged in a front end inner cavity of the medical syringe, a square battery and a high-voltage direct-current inverter are arranged fixedly on the side wall of the syringe in a butt joint mode, and a stainless steel needle head which is used for spinning is arranged at the bottom end of the syringe in an inserting mode. A conventional medical syringe needle head structure and the syringe are combined and matched, the spinning solution is stored in the inner cavity of the medical syringe which is provided with the stainless steel needle head, the square battery provides a power supply for the high-voltage direct-current inverter, when the direct current voltage is inverted, the voltage in the unit of kilovolt, the positive pole of the high-voltage direct-current inverter is communicated electrically with the stainless steel needle head, and the negative pole of the high-voltage direct-current inverter is communicated electrically with the metal foils. The device is simple in overall structure, is convenient to carry, use and operate, applicable to occasions such as outdoor teaching and wounded rescue and high in economical value.