Propolis soft capsule and preparation method thereof

A soft capsule, propolis technology, applied in food preparation, capsule delivery, pharmaceutical formulations, etc., to improve immunity, use safety, improve and prevent chronic complications of diabetes

Inactive Publication Date: 2014-03-19
JIANGSU JIANGDAYUAN ECOLOGICAL BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no literature report at present, and the research results of the above two aspects can b

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A kind of propolis soft capsule and preparation method thereof, its preparation method is as follows:

[0030] (1), propolis supercritical CO 2 Preparation of extract: using simulated biological fluidized bed supercritical CO 2 The method of fluid extraction of propolis (ZL200910030879.3) extracts propolis to obtain propolis supercritical CO 2 extract, spare;

[0031] (2) Chemical glue: Heat 42kg glycerin and 100kg purified water to 70-80℃, add 100kg gelatin, stir until all gelatin is dissolved, vacuumize for 15-30 minutes to remove air bubbles, filter with 150 mesh filter bag, release Keep warm in the glue barrel to get the glue of the rubber, for subsequent use, the heat preservation temperature of the glue barrel is 60-70°C;

[0032] (3) Pretreatment of the contents of the capsule: Weigh 195.5kg of wheat germ oil according to the formula, filter it with a 300-mesh filter bag, pour 175.5kg of wheat germ oil into a vacuum emulsifier and heat it to 50°C, add 100kg of...

Embodiment 2

[0038] A kind of propolis soft capsule and preparation method thereof, its preparation method is as follows:

[0039] (1), propolis supercritical CO 2 Preparation of extract: using simulated biological fluidized bed supercritical CO 2 The method of fluid extraction of propolis (ZL200910030879.3) extracts propolis to obtain propolis supercritical CO 2 extract, spare;

[0040] (2) Glue: Heat 42kg glycerin and 100kg purified water to 70-80°C, add 100kg gelatin, stir until the gelatin is completely dissolved, vacuumize for 30 minutes to remove air bubbles, filter with a 150-mesh filter bag, and release the gelatin Insulation in the liquid barrel, get the glue of rubber, standby, the heat preservation temperature of described glue barrel is 65 ℃;

[0041] (3) Pretreatment of the contents of the capsule: Weigh 178.6kg of wheat germ oil according to the formula, filter it with a 300-mesh filter bag, pour 158.6kg of wheat germ oil into a vacuum emulsifier and heat to 50°C, add 100k...

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PUM

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Abstract

The invention relates to a propolis soft capsule. The propolis soft capsule comprises a rubber sheet and a capsule content, wherein the capsule content comprises the following components in percent by weight: 20%-60% of propolis supercritical CO2 extract, 30%-70% of wheat-germ oil and 1%-10% of vitamin E; components of the rubber sheet are gelatin, glycerol and purified water in a weight ratio of 100:42:100. The propolis soft capsule is integrated with improving effect of propolis on diabetes mellitus and preventing effect of vitamin E on chronic complication of the diabetes mellitus; moreover, the components are good in synergistic effect. The invention also provides a preparation method of the propolis soft capsule.

Description

technical field [0001] The invention relates to a propolis health food with regulating effects on human immunity and blood sugar, in particular to a propolis soft capsule and a preparation method thereof. Background technique [0002] Diabetes is a lifelong disease that is ravaging the world. The incidence rate in the world is increasing year by year, and it has been listed as the third largest disease after cardiovascular disease and tumor. The prevalence of diabetes in my country is 3.2%, and the total number has increased nearly five times in the past 20 years. At present, the greatest hazard of diabetes to human health is the various chronic complications based on arteriosclerosis and microvascular disease, such as diabetic heart disease, diabetic gangrene, diabetic cerebrovascular disease, diabetic nephropathy, diabetic retina disease and neuropathy. The number of blindness caused by diabetes is 10-25 times more than the average person, the number of diabetic gangren...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L1/076A61K36/899A61K9/48A61P3/10A61P37/04A61K35/64A61K31/355A23L33/00A23L21/20A61K35/644
CPCA23L33/10A23L21/20A23L33/15A23P10/35A23V2002/00A23V2200/324A23V2200/328A23V2250/11A23V2250/134A23V2250/18A23V2250/204A23V2250/502A23V2250/6406A23V2250/712A23V2300/14A23V2300/50
Inventor 毛日文朱惠芬张林
Owner JIANGSU JIANGDAYUAN ECOLOGICAL BIOLOGICAL TECH
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