4 results about "Schizandrol A" patented technology

The application discloses a quality detection method for a compound phyllium panax schisandra preparation, and belongs to the technical field of drug detection and analysis. The traditional Chinese medicine is composed of phyllium, panax and schisandra. Qualitative analysis is conducted on the phyllium, panax and schisandra in the compound by using a thin layer chromatography method; and the contents of gallic acid, ginsenoside Rg1 and schisandrin A in the compound are determined by using a high performance liquid chromatography method. The thin layer chromatography method is one of classical traditional Chinese medicine analysis methods, and has the advantages of rapidness, convenience and the like; the high performance liquid chromatography method is also one of classical traditional Chinese medicine analysis methods, and has the advantages of mature technology, good stability, high universality and the like, can be used for widely and accurately detecting chemical components in a complex traditional Chinese medicine compound, the content determination method passes the method validation, has good linear relationship, and the precision, stability, repeatability and recovery rate meet the regulations, and the combination of qualitative analysis and quantitative analysis lays a foundation for establishing the quality standard of the compound preparation.

The application discloses a capsule for assisting in protecting chemical liver injury and a preparation method thereof, and belongs to the technical field of health-care food. The capsule is composed of curcuma longa extract 100g, silybum marianum extract 70g, schisandra chinensis extract 60g, microcrystalline cellulose 109.5g, silicon dioxide 7g and magnesium stearate 3.5g, and 1000 capsules are taken as a unit. The curcuma longa extract contains curcumin, the content of which is greater than or equal to 10% (10:1), the silybum marianum extract contains silybin, the content of which is greater than or equal to 20% (25:1), and the schisandra chinensis extract contains schisandrin, the content of which is greater than or equal to 1.5% (12.5:1). The three kinds of plant extracts are scientifically compounded, and the effects of antioxidation, anti-inflammation, liver cell membrane protection and bile secretion regulation are synergistically exerted. Through systematic screening of the types and dosages of the filling agent, the flow agent and the lubricant, the technical problems of poor flowability of the mixed plant extract powder, large filling difference and easy jamming are solved.

This invention provides a *Bacillus hygroscopicus* strain and its application, relating to the field of microbial fermentation technology. The strain is named *Bacillus hygroscopicus* (…). Bacillus altitudinis Bacillus subtilis (W09), deposited at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, China, Institute of Microbiology, Chinese Academy of Sciences, on December 26, 2025, with accession number CGMCC No. 37218. This invention provides Bacillus subtilis (W09). Bacillus altitudinis W09 can be used to increase the content of schisandrol A in the fermentation products of Schisandra chinensis vine stems.

This invention discloses a method for determining the content of codonopsis glycosides in Shengmai Yin soft capsules, belonging to the field of traditional Chinese medicine preparation quality testing technology. The method employs high-performance liquid chromatography (HPLC) with octadecylsilane-bonded silica gel as the packing material, methanol-water (40:60) as the mobile phase, a detection wavelength of 267 nm, and a column temperature of 40℃. The test sample is prepared by reflux of 30% methanol for 30 minutes. Method validation showed that codonopsis glycosides exhibited good linearity in the range of 0.02608 μg–0.28688 μg (r = 0.9999). The instrument precision, repeatability, stability, and recovery rate all met the requirements for quantitative analysis, and the negative control showed no interference. This method is highly specific, simple to operate, and provides accurate and reliable results. It enables precise control of the key components of the principal herb, Codonopsis pilosula, overcoming the shortcomings of the original standard which only determined schisandrol A. It is suitable for quality control, production process optimization, and product quality improvement of Shengmai Yin soft capsules.