The invention discloses rhizoma polygonati health care wine. The rhizoma polygonati health care wine is prepared from white wine with alcohol content of 35 degrees and the following traditional Chinese medicines (TCMs): rhizoma polygonati, Chinese magnoliavine fruit, roses, common anemarrhena rhizome, officinal magnolia bark, orange fruit, Chinese arborvitae kernel, dark plums, fiveleaf gynostemma herb, common fenugreek seed, India madder root, long pepper, tuber onion seed, pseudo-ginseng, glabrous greenbrier rhizome, great burdock achene, Japanese thistle root, glossy privet fruit, radix codonopsis, white mulberry root-bark, purslane herb, Sichuan lovage rhizome, tall gastrodia tuber, manyprickle acathopanax root, hirsute shiny bugleweed herb, rhizoma drynariae, radix onosmatis, solms-laubachia pulcherrima, herba artemisiae adamsii, sandwort and eriophyton wallichii. The health wine takes the pure TCMs as the raw materials and various TCMs are organically matched and combined. The rhizoma polygonati health wine is easy to absorb by human bodies, has the functions of tonifying middle jiao and qi, warming the spleen and the kidney, achieving nourishing and health care, enhancing the immunity, invigorating the stomach to help digestion, enhancing the physique and improving the sleep quality, is simple in preparation method, is convenient to take, is safe, does not have toxic or side effects and has good taste.