496 results about "Triterpenoid saponin" patented technology

The invention relates to a non-bleeding concrete pumping admixture with high durability and high slump retaining, the raw material weight percentage composition of which is: 25 to 45 percent of naphthalene series water reducer, 2 to 6 percent of polycarboxylic series of water reducer, 1 to 4 percent of sodium lignosulfonate, 0.5 to 2 percent of sodium gluconate, 0.2 to 2 percent of triterpenoid saponin, 0.5 to 3 percent of carboxymethyl cellulose, 0.2 to 1 percent of silicon oil, and 40 to 65 percent of water; the non-bleeding concrete pumping aid with high durability and high slump retaining has the advantages of low slump loss and low cost, no bleeding, restraining the shrinkage of concrete, and controlling the fissure of concrete.

The invention relates to a liquid cement grinding aid which can obviously reduce the dosage of trolamine and does not contain urea. The grinding aid comprises the following compositions in weight percentage: 1 to 10 percent of trolamine, 5 to 10 percent of diglycol, 1 to 10 percent of trimeric sodium phosphate, 10 to 30 percent of molasses, 0 to 20 percent of sodium thiosulfate, 0 to 10 percent of air entraining component and the balance being water, wherein the air entraining compositions are triterpenoid saponin air entraining agent, sodium lignin sulfonate or a mixture of the triterpenoid saponin air entraining agent and the sodium lignin sulfonate at any proportion. The invention obviously reduces the dosage of the trolamine, does not contain the urea, lowers product cost and simultaneously facilitates the environmental protection. The sodium thiosulfate has the function of exciting mixed materials of cement and can improve the initial strength and the later strength of the cement, thereby effectively improving the service performance of the cement grinding aid. The triterpenoid saponin air entraining agent and the sodium lignin sulfonate have the action of the auxiliary aided grinding and simultaneously properly entrain air to reduce the water consumption of the cement standard consistence.

The invention pertains to the field of medical technology and provides triterpenoid saponin in camellia seeds, and a preparation method and medical application thereof. The triterpenoid saponin is shown in a general formula (1), wherein, R1 is hydrogen or oxhydryl or acyloxy; R2 is the hydrogen or the acyloxy; R3 is the hydrogen or the acyloxy; R4 is the hydrogen or the acyloxy; R5 is methyl or methylol or aldehyde group or carboxyl or metheyl carboxyl; R6 is the hydrogen or orglycosyl; the preparation method comprises the following steps: macroporous resins are degreased, extracted by ethanol, decocted in water, desugared and decolored to obtain crude total saponins and then go though an opened ODS chromatographic column and repeated HPLC method to obtain the total saponins of camellia seeds and monomer theasaponin. The triterpenoid saponin compounds in the camellia seeds have the functions of protecting gastric mucosa, being antineoplastic, reducing blood sugar and blood fat and thelike and are used for preparing medicaments or health-care foods having the functions of protecting gastric mucosa, being antineoplastic and reducing blood sugar and blood fat.

Two hitherto unreported novel triterpene saponins were isolated in substantially pure form from the root of Ilex pubescens. The chemical structures and some properties of the triterpene saponin fraction have been elucidated to possess anti-inflammatory and analgesic activity. These two novel triterpene saponins and the triterpene saponin fraction may be used as pharmaceutical compositions in humans and mammals in need of such treatment.

The invention discloses a cement concrete antifreezer, which comprises the following components in part by weight: 15 to 30 parts of high-performance polycarboxylate water reducer, 20 to 30 parts of low molecular weight alcohol, 0.1 to 0.15 part of triterpenoid saponins, 10 to 30 parts of calcium formate, 2 to 5 parts of organic alkylol amine and 50 to 70 parts of water, wherein the triterpenoid saponins is used for entraining air to form a large number of superfine air bubbles and improve the frost heaving stress of concrete. By the cement concrete antifreezer, the concrete can be subjected to construction at the temperature of between -20 and -30 DEG C.

The invention discloses an anti-flaming antisepsis leather coating which is composed of, by weight, 2-3 parts of hydrous zinc borate, 1-1.5 parts of linoleic acid calcium soap, 0.1-0.2 part of triterpenoid saponin, 0.7-1 part of calcium naphthenate, 1.7-2 parts of polyvinylpyrrolidone, 0.8-1 part of polyacrylamide, 1.6-2 parts of stannous chloride, 0.1-0.13 part of triethanolamine, 190-200 parts of methyl methacrylate, 3-4 parts of lauryl sodium sulfate, 0.1-0.2 part of urotropine, 0.2-0.3 part of ammonium persulfate, 6-7 parts of a 20%-25% formaldehyde solution, 16-20 parts of zinc acetate, 4-7 parts of silver nitrate, 1-2 part of decabromodiphenyl ether and 0.4-1 part of sodium lauryl sulfate. The anti-flaming antisepsis leather coating has a good antibacterial property and excellent moisture permeability and water resistance. Leather coated with the obtained emulsion is good in antibacterial property and excellent in hygiene property.

The invention relates to a polycarboxylic acid type special additive for lightweight aggregate concrete, which is formed by uniformly mixing 40-50 parts by weight of polycarboxylic acid type water reducing agent, 0.5-6 parts by weight of sodium gluconate, 0.1-0.4 part by weight of triterpenoids saponin, 0.05-0.2 part by weight of defoamer BYK-024 and 0.005-0.02 part by weight of cellulose ether with 50-60 parts by weight of water. The adoption of the special additive can lead lightweight aggregate to be difficult to float, avoid causing great impacts on the working performance of concrete, further avoid increasing the loss of slump constant, well control the performances of workability and homogeneity of the concrete, simplify the production process of the lightweight aggregate concrete, improve the production efficiency, simultaneously improve the construction working efficiency and obtain obvious economic benefits and social benefits.

The invention discloses a liquid cement grinding aid. The grinding aid consists of the following compositions in weight percentage: 5 to 20 percent of trolamine, 5 to 20 percent of diglycol, 10 to 30 percent of lactose, 1 to 5 percent of triterpenoid saponin air entraining agent, 1 to 5 percent of sodium lignosulphonate and the balance being water. The technical proposal has a function of properly entraining air to reduce the water consumption of the cement standard consistence. The further optimum proposal of the invention is to add sodium nitrite with a mass ration of between 5 and 20 percent based on the technical proposal. The technical proposal can improve the later strength of cement and enhance the corrosion-inhibiting capability of reinforced concrete; meanwhile, the invention also discloses a preparation method of the liquid cement grinding aid.

The invention belongs to the technical field of medicaments, and provides a method for preparing total triterpene of Chinese medicament garden burnet root. The total triterpene is mainly obtained by performing reflux extraction by 70 percent ethanol, absorbing by a macroporous absorbent resin, using water to wash off impurities, using ethanol solution for elution, then decolorizing an eluent by daiamid powder, using the ethanol solution for elution, and recovering the ethanol through pressure reduction. The total triterpene mainly contains triterpenic acid active components such as arjunic acid, 1beta-euscaphic acid, euscaphic acid, tormentic acid and the like, and triterpenoid saponin active components such as sanguisorbin I, sanguisorbin II, sanguisorbin III, niga-ichigoside, kaji-ichigoside F1 and the like. Experimental results show that the total triterpene has remarkable anti-inflammatory and analgesic effects. The total triterpene has definite action substance basis and action mechanism as well as simple preparation technology, is suitable for industrialized production, can be taken as medicinal raw materials for treating inflammatory diseases such as burn and scald, rectitis, ulcerative colitis, pyelonephritis and the like, and is prepared into clinically acceptable dosage forms such as tablets, capsules, granules or compound preparations according to the prior process.

The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.

The invention discloses a compound microorganism silage additive and an application to preparation of grain amaranth silage. The compound microorganism silage additive comprises an enzyme and bacteria compound and an amaranth root extract, enzyme in the enzyme and bacteria compound comprises cellulase, hemicellulose, amylase, pectinase, protease and the like, bacteria in the enzyme and bacteria compound comprise a lactobacilli flora, a bacillus thuringiensis group, photosynthetic bacteria, a yeast flora, an actinomycete group, filamentous bacteria and the like, and main components of the amaranth root extract include plant sterol, polysaccharide, oleanolic acid, flavonoid, triterpenoid saponins, organic acid and the like. Compared with a conventional silage additive, the compound microorganism silage additive is good in fermentation effect and palatability. The grain amaranth silage is prepared from the compound microorganism silage additive, the potential advantage of raw materials serving as green feed can be effectively improved, daily gain can be remarkably increased, feed-meat ratio is increased, animal growth is promoted, and the grain amaranth silage can be widely used for livestock and poultry breeding and aquaculture.

The invention provides methods for the isolation of plant genes and their regulatory sequences involved in the biosynthesis of triterpene saponins. Also provided by the invention are genes involved in the biosynthesis of triterpenes, including squalene synthase, squalene epoxidase and beta-amyrin synthase from Medicago truncatula. The identification of triterpene biosynthesis genes allows genetic modification of the content and composition of triterpene saponins in plants for crop improvement and the development of drugs, nutriceuticals and functional foods.

The present invention relates to a loquat flower tea beverage product and its preparation method. Said invention uses loquat flower and Chinese medicinal herbs with refreshing effect or tea as raw material and adopts the following processes: soaking the above-mentioned raw materials in boiling water to make extraction, mixing extracted filtrate with sweetening agent and water according to a certain ratio, fine filtering, UHT sterilization and sterile hot-filling so as to obtain the invented product. Said product comprises medicinal components of triterpenoid saponin, etc. and at the same time contains amino acids necessary for human body, nucleic acid, vatmins and various mineral components of Ca, Zn and Fe, etc. Besides, said beverage also has various health-care functions.

The invention relates to a method for analyzing effective components of a drug, in particular to a method for analyzing effective components of an astragali radix and poria preparation with effects of warming the spleen and eliminating cysts. The method comprises the steps as follows: (1) preparation of a control solution; (2) preparation of a test article solution; (3) analysis method of the effective components including flavonoids, phenolic acids, triterpenoid saponins, sesquiterpene glycosides and alkaloids.

The invention discloses a notoginsenoside ST-4 which is a new dammarane type triterpenoid saponin compound shown in the structural formula (I), and a preparation method thereof. The invention also provides applications of the notoginsenoside ST-4 in the preparation of drugs against HSV-1. An HSV-1 strain and HELF (MRC-5) are used as cell experimental subjects to carry out the experiment of antiviral activity of the new compound which is the notoginsenoside ST-4. The results show that the notoginsenoside ST-4 has therapeutical effect for cells infected by HSV-1 and can reduce the infectivity of HSV-1 for MRC-5 cells and be applied to the preparation of drugs against HSV-1.

The invention discloses a sea cucumber saponin, a preparation method thereof and the application thereof in food or medicines. A sea cucumber saponin mixture comprises multiple sea cucumber alkyl-type triterpenoid saponins. Preferentially, the sea cucumber saponin mixture comprises holothurin A and/or echinoside A. The sea cucumber saponin mixture can also comprise one or more in holothurin A, holothurin B, echinoside A, echinoside B, 24-dehydroechinoside A and stichoposide E. The sea cucumber saponin can be applied to preparing weight-losing food or medicines, and animal experimental resultsshow that the sea cucumber saponin can be used for remarkably inhibiting weight increment and reducing internal fat accumulation so as to realize a good weight-losing effect. The preparation method of the sea cucumber saponin is low in cost, simpler in steps and less in the pollution of organic solvents on the environment; and through animal experiments, the prepared sea cucumber saponin is proved to have a good weight-losing effect so as to be used for developing safe and effective weight-losing food or medicines.

The invention is a special additive for post-tensioned cohesive prestressed concrete structure, prepared of the following components in weight percent: phenyl sulfonate formaldehyde high-grade condensation compound 2-10%, aluminum powder 0.005-0.05%, anhydrite 50-70%, calcined kaoline 10-20%, kaoline 10-20%, linear high-molecular anion polysaccharide 0.05-1.5%, and triterpenoid saponin 0.05-0.1%. It has multiple functions of improving both the rheological property of grouting material and the bulk stability, and after doped, it is unnecessary to compound other materials to effectively improve the rheological property of grout, largely reducing seepage water and avoiding high separation and stratification, and it can effectively compensate shrinkage in plastic and hardening state, enhancing the bulk stability of the grout. The fluidity is basically not lost in 2 hours, the grout is full and dense in the pipeline and has strong adaptability to temperature, and the economic benefits of the technique are obvious. After doped in the cement, it adopts ordinary pressure grouting technique to be able to effectively ensure the grout basal body does not seep water after grouted and the bulk of the grout does not shrink and corrode steels.

The invention discloses a method for performing qualitation and quantification on triterpenoid saponin in traditional Chinese medicine by utilizing an electrospray protonation pyrolysis-mass spectrummulti-reaction detection mode. The triterpenoid saponin can form a stable [M+H]<+> and/or [M+NH4)<+> molecular ion peak in a flow phase containing formic acid or ammonium formate. According to the method disclosed by the invention, a liquid chromatogram-tandem quadrupole mass spectrometry combined instrument is utilized, an electrospray positive ion tandem mass spectrum detection mode is utilized,and mass spectrum parameters of declustering potential, impact energy, impact chamber injection voltage and the like can be quickly optimized in an online mode by a single factor and response surfacemethod; thus, high-strength triterpenoid saponin protonation pyrolysis MRM target ion pairs can be formed; a Q1 calculation formula is [M+H]<+> or [M+NH4]<+>, and a Q3 calculation formula is [aglycone +H-nH2O]<+>. By means of the series of characteristic MRM target ion pairs, the purpose of quick qualitative and quantitative detection on the triterpenoid saponin in the traditional Chinese medicine is realized. The method disclosed by the invention provides an effective technology method for the qualitative and quantitative detection on the triterpenoid saponin in the traditional Chinese medicine and has been successfully applied to content measurement on the triterpenoid saponin of caulophyllum robustum and aralia elata.