507 results about "Ion pairs" patented technology

The present invention provides a comprehensive solution to skin problems of infants and incontinent adults related to diaper rash, also known as diaper dermatitis. This is based on certain novel divalent metal and quaternary ammonium complexes (ion-pairs) of zeolites (that are made by an in-situ process), which in synergistic combination with certain other compositions, provide a comprehensive treatment for diaper rash that encompasses the following aspects: (1) deactivation of lipase and protease enzymes on skin surface, (2) the controlled-release delivery of skin protectant compositions, such as divalent metal zinc cation, (3) trapping of acidic and alkaline chemicals deposited on skin from body exudates and enzyme activity, (4) controlled-release delivery of anti-inflammatory agents, and COX and LOX enzyme inhibitors, (5) controlled-release delivery of antibacterial and antifungal compositions, and (6) absorption of excess moisture in the diaper zone.

The current landscape for preparative chromatographic RNA purification uses reversed phase HPLC, but this technique presents many issues with process scale up and ion exchange for preparative purification has only been used for short RNAs. The invention provides preparative purification of RNA (e.g., mRNA) using ion (e.g., anion) exchange chromatography that allows for separation of longer RNAs up to 10,000 nucleotides in length via a scalable method. This method avoids problems with current techniques by using low pressure chromatography that is agreeable with existing equipment in cGMP commercial facilities, that uses aqueous-bases solutions as the mobile phase (rather than flammable of greater than 10 mg RNA/mL resin (e.g., using larger pore sorbents, >500 Angstroms, that display greater mRNA binding capacities), and that yields desired RNA salt forms for downstream formulation with no additional manipulation necessary (unlike ion pair reverse phase techniques).

This invention relates to a novel ion-pair delivery system useful for cosmetic, pharmaceutical, and topical nutraceutical applications in which the functional performance and consumer aesthetics of an electron donor composition and an electron acceptor composition, or a proton donor composition and a proton acceptor composition, are synergistically enhanced when such compositions are combined in an ion-pair mode. During ion-pair bonding process, the electron donor composition or the proton acceptor composition become positively charged and the electron acceptor composition or proton donor composition become negatively charged and thus bind together in an ionic manner. Such ion-pair compositions release their electronically bound components in their original state when such compositions are absorbed into skin and reach physiological pH conditions.

An olefin polymer production method is provided by which olefin polymers can be obtained at high polymerization activity under the conditions of reduced hydrogen concentration. Silyl-terminated olefin polymers may be obtained by this method. The olefin is polymerized using a catalyst of a transition metal compound (A) of Groups 3 to 10 of the periodic table, at least one compound (B) selected from organoaluminum oxycompounds (B-1), compounds (B-2) that react with the abovementioned compound (A) to form an ion pair, and organoaluminum compounds (B-3), under the coexistence of an organosilicon compound (C) or dialkylzinc compound (D) and in the presence or absence of hydrogen (E).

Methods of producing stable dispersions of single-walled carbon nanotube structures in solutions are achieved utilizing dispersal agents. The dispersal agents are effective in substantially solubilizing and dispersing single-walled carbon nanotube structures in aqueous solutions by coating the structures and increasing the surface interaction between the structures and water. Exemplary agents suitable for dispersing nanotube structures in aqueous solutions include synthetic and natural detergents having high surfactant properties, deoxycholates, cyclodextrins, chaotropic salts and ion pairing agents. The dispersed nanotube structures may further be deposited on a suitable surface in isolated and individualized form to facilitate easy characterization and further processing of the structures.

The invention relates to a novel veterinary antibacterial agent and in particular relates to a lauroyl arginine ethyl ester ion pair compound derivative which is prepared from lauroyl arginine ethyl ester LAE and an organic acid through reactions. As a livestock aquatic animal antibacterial agent, the derivative is capable of preventing and treating duckling riemerella anatipestifer diseases caused by riemerella anatipestifer, is capable of treating peritonitis diseases caused by escherichia coli and staphylococcus aureus, is capable of preventing and treating fish septicemia caused by aeromonas sobria, and has remarkably improved prevention and treatment effects when being compared with a conventional LAE veterinary antibacterial agent. The derivative can be completely degraded in human bodies and animal bodies and is small in toxic and side effect, environment drug resistance bacteria caused by residual antibacterial agents discharged into the environment can be avoided, and small adverse environment influence can be caused while an effective antibacterial effect is achieved.

Micro neutron detectors include relatively small pockets of gas including a neutron reactive material. During use, under a voltage bias in a neutron environment, neutron interactions in the neutron reactive material are seen to occur. Ultimately, electron-ion pairs form and positive ions drift to a cathode and electrons to the anode. The motion of charges then produces an induced current that is sensed and measurable, thereby indicating the presence of neutrons. Preferred pocket volumes range from a few cubic microns to about 1200 mm³; neutron reactive materials include fissionable, fertile or fissile material (or combinations), such as ²³⁵U, ²³⁸U, ²³³U, ²³²Th, ²³⁹Pu, ¹⁰B, ⁶Li and ⁶LiF; gasses include one or more of argon, P-10, ³He, BF₃, BF₃, CO₂, Xe, C₄H₁₀, CH₄, C₂H₆, CF₄, C₃H₈, dimethyl ether, C₃H₆ and C₃H₈. Arrangements include two- and three-piece sections, arrays (including or not triads capable of performing multiple detecting functions) and/or capillary channels.

The invention belongs to a preparation method of a nanometer functional material and especially relates to the field of application of a nitrogen-doped porous carbon material to environment protection. A preparation method of a nitrogen-enriched porous carbon desulfurizer with superhigh specific surface area comprises the following steps: firstly, mechanically mixing a micromolecular biomass precursor and inorganic molten salt, placing the mixture into a quartz tube, and carbonizing in an inert atmosphere. By the utilization of polymerization among the precursor in the heating process and phase separation of carbon generated by carbonization and fuse salt, ion pair or cluster formed by fuse salt is used as a pore forming agent; and washing is followed to remove the molten salt so as to obtain the nitrogen-doped porous carbon desulfurizer. The nitrogen-doped porous carbon has a well-developed pore structure and rich nitrogen-containing function group, can be used as a non-metal catalyst for catalytic oxidation of hydrogen sulfide at room temperature to convert to elemental sulfur, and has a wide application prospect in the field of environment protection. In addition, the method has characteristics of simple operation, low cost, environment-friendly preparation and easy industrial production, and is an important carbon nanomaterial preparation method.

A process for producing a bis(fluorosulfonyl)imide anion compound by substituting a bis(chlorosulfonyl)imide anion compound, obtained from sulfamic acid, chlorosulfonic acid, and a halogenating agent, with fluorine is used as a process for producing a fluorine compound for use, for example, in the synthesis of battery electrolytes and ionic liquids. According to the above process, the inclusion of impurities can be reduced, and a high-purity fluorine compound of a bis(fluorosulfonyl)imide compound can be efficiently produced at a high yield. A base catalyst can be used in the reaction for substituting the bis(chlorosulfonyl)imide anion with fluorine. The base catalyst is preferably a nitrogen-containing compound.

The embodiment of the invention provides a method for detecting 25(hydroxyl)vitamin D by using a high-pass liquid chromatography-tandem mass spectrometry. The method comprises the following steps of: adding an acetonitrile solution containing an internal standard substance of the 25(hydroxyl)vitamin D into a human serum sample to carry out protein precipitation; sufficiently and uniformly mixing the solution, and then, adding an n-hexane extracting solvent; sufficiently and uniformly mixing the solution, then centrifuging the solution, movably taking a supernatant and drying the supernatant, and adding a complex solution to obtain a sample to be detected; detecting the sample to be detected by using a high-pass liquid chromatography-tandem quadrupole mass spectrometer; and quantifying according to the relative retention time of 25(hydroxyl)vitamin D2 and/or 25(hydroxyl)vitamin D3 and the detected abundance ratio of quantitative ion pairs by using an internal standard curve method. According to the embodiment of the invention, the method has the advantages of simplicity in pretreatment, strong specificity and matrix interference resistance, short detection time, high pass, high detection precision and low cost.

The invention provides a recovery method for a waste ferric trichloride etching liquid. The method adopts integrated membrane electrolysis and extraction technology and comprises the following steps: providing an electrolytic tank, wherein an ion exchange membrane is arranged in the electrolytic tank to divide the electrolytic tank into an anode chamber and a cathode chamber, and a cathode and an anode are respectively positioned in the cathode chamber and the anode chamber located at two sides of the ion exchange membrane; adding the waste ferric trichloride etching liquid into the cathode chamber and carrying out membrane electrolysis so as to reduce Fe3+ ions into Fe2+ ions; carrying out extraction on a solution obtained after electrolysis in the cathode chamber to remove impurity metals so as to obtain an extract phase solution and a metal impurity-removed phase solution and delivering the metal impurity-removed phase solution to the anode chamber for membrane electrolysis so as to oxidize Fe2+ ions into Fe3+ ions; and recovering a solution obtained after electrolysis in the anode chamber. Compared with conventional processing technology for the waste ferric trichloride etching liquid, the recovery method provided by the invention has the advantages of short and simple process flow, no generation of secondary pollution, no discharge of waste gas, waste water and industrial residue, low production cost, applicability to large-scale treatment, treating capacity of more than ten thousands every year and good environmental and economic benefits.

The invention provides a method for the preparation of the composite chromatographic stuffing of the polymer carbon nanometer tube, comprising: taking polystyrene-divinylbenzene and carbon nanometer tube as the base material, adopting the dispersion polymerization method to prepare monodispersity linear polystyrene microsphere seed, activating the feed, taking uni-step seed swell method to prepare the polystyrene-divinylbenzene and carbon nanometer tube composite microsphere, extracting to remove the pore-foaming agent to obtain the chromatographic stuffing, packing column by the uniform method. The stuffing prepared by the method has uniform granularity without screening and enhanced hardness compared with the traditional polymer chromatographic stuffing, can bear bigger pressure and is suitable for the new UPLC. The obtained polystyrene-divinylbenzene and carbon nanometer tube liquid phase chromatographic column can be stably used for the ion-pair chromatograph for along time and better performs the simultaneous separation of over ten organic acids.

The purpose of the present invention is to provide an aluminum electroplating solution that allows aluminum electroplating to be conducted efficiently and in a short period of time, can increase the amount of electricity in the current of electroplating, and has high solubility in a nonaqueous solvent. This aluminum electroplating solution is characterized by comprising an aluminum metal salt, an ionic liquid obtained by an organic compound forming an ion pair with the aluminum metal salt, and an organic solvent having a dielectric constant of 8 or less. It is preferable for the volume percentage of the organic solvent in relation to the total volume of the ionic liquid and the organic solvent to be at least 30%, and for at least one of the following to be included as the organic solvent having a dielectric constant of 8 or less: hexane, toluene, diethyl ether, ethylacetate, cyclohexane, xylene, benzene, naphthalene, heptane, cyclopentyl methyl ether, and dioxane.

The invention relates to a method for detecting low-molecular-weight heparin by combining ion pair reversed phase chronmatogaphy and mass spectrum. The method comprises the steps of: detecting all compositions of low-molecular-weight heparin by combining ion pair reversed phase chronmatogaphy and high-resolution mass spectrum, separating main compositions from a sample through the ion pair reversed phase chronmatogaphy, obtaining precise molecular weight by the high-resolution mass spectrum, and calculating information of a carbohydrate chain sequence, including structures of two ends, length of a carbohydrate chain and substitution number of ethanoyl and sulfate, thus carrying out fine surface features on the low-molecular-weight heparin. The method has great practical values on improving the heparin detection level and ensuring drug safety.

The invention relates to a method for producing organic hybridization amphoteric ion pair to membrane material. Its characteristic is: carrying on amination reaction to hybridization forerunner body under 0-90deg.c the temperature to make it contain an anionic exchange groups, and then carrying on sulfonation or oxidation reaction to make it contain a cation exchange groups. Obtained anionic exchange groups and anionic exchange groups simultaneously, or carrying on sulfonation or oxidation reaction to hybridization forerunner body, and then carrying on amination reaction. The cation exchange groups arrange at the both side of backbone or on backbone. The anionic exchange groups arrange on backbone all the time to form the amphoteric ion pair structure with the cation exchange groups. Thismaterial has good flexibility, high heat resistance. The exchange capacity depends on the producing process. It can be used in producing exchange membrane material, separating the electrolyte and thenonelectrolyte and separating multivalence.

Nucleophilic substitution reactions of halogenated polymers and azoles are used to produce derivatives of polyolefins bear pendant azolium ionomers. These uncured ionomers are useful in adhesive, antimicrobial applications, as well as in polymer composites and polymer blends. Furthermore, these azolium ionomers' ion pairs can bear reactive functionality, which provides access to further reactions that were unavailable using previous technology. Advantageously, such reactive ionomer derivatives of polyolefins can be cured by free radical and moisture-curing chemistry that was unaccessible to the halogenated polymer parent material.

The invention provides a method for detecting 25-hydroxy-vitamin D through a high-sensitivity high-throughput ultra-performance liquid chromatography-tandem mass spectrometry device. The method comprises adding an internal standard substance of 25-hydroxy-vitamin D into a serum sample, adding a zinc sulfate solution and a methanol solution into the mixture so that protein deposition is realized, carrying out full mixing, adding a n-hexane solvent into the mixture, carrying out extraction, carrying out full mixing, carrying out centrifugation, taking the supernatant, carrying out nitrogen blowing drying, adding a compounded solution into the supernatant to obtain a sample to be detected, detecting the sample to be detected through an ultra-performance liquid chromatography-tandem quadrupole mass spectrometry device and carrying out quantitation through an internal standard curve method based on 25-hydroxy-vitamin D2 and/or 25-hydroxy-vitamin D3 quantitative and qualitative ion pair retention time as qualitative basis. The method has advantages of simple pre-treatment process, good specificity, good matrix interference resistance, short detection time, high throughput, high detection precision, high sensitivity and low cost.