374results about How to "Cut skin" patented technology

Methods and apparatus are disclosed for applying acoustic energy to the skin. Acoustic waveguides with elements of varying thickness or shape are disclosed which deliver energy to more than one depth below a surface of the skin substantially simultaneously. The invention is especially useful with devices that focus ultrasound energy by condensing a propagating wavefront. The invention compensates for the mismatch in acoustic properties of the device's waveguide and the biological tissue that typically cause portions of the collapsing wavefront to lag behind other portions and, thereby, limit the focusing capabilities of acoustic treatment devices.

An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.

The present invention relates generally to composition and methods for topical application to skin. More particularly, it relates to treatment of scars and rosacea, and other aspects of skin care. A composition is disclosed having a skin toner for cleansing a skin surface, removing dead skin cells, restoring alkali balance, and shrinking skin pores; and a skin moisturizer for increasing water content in the external layers of the skin.

An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.

The present invention is directed to the treatment of skin erythema as exhibited in rosacea and other conditions characterized by increased erythema (redness) of the skin. These conditions exhibit dilation of blood vessels due to a cutaneous vascular hyper-reactivity. In particular, the present invention is directed to a novel composition and method for the treatment of skin erythema using α₁-adrenergic receptor (α₁-adrenoceptor) agonists incorporated into cosmetic, pharmacological or dermatological compositions for topical application to the skin.

Implantable subcutaneous device of biocompatible material that can receive data and energy by electromagnetic coupling with at least one external device is disclosed. The implantable device bears an airtight housing and a magnet that can hold the other external device centered with the implantable device. The housing bears a hollow crown containing at least electronic device(s) and a coil, and a bottom sealing the opening of the crown in an airtight manner, The magnet has dimensions compatible with a central housing formed by the so-called internal wall of the crown and in which it is positioned.

The present invention relates to a composition consisting of a combination of peptides that regenerate the dermal matrix and a rapid acting muscle relaxant derived from the extract of the plant, Acemella oleracea. By limiting cutaneous deformation caused by the contraction of facial muscles the extract increases the efficiency of the peptides in reducing expression lines.

Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies of skin and hair. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes affecting skin and hair.

The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (Iysyl oxidase-like) isoform. The invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers.

The expulsion liner is for use with a prosthetic device to be secured to a residual limb. The expulsion liner includes an elongated elastomeric tube having a closed distal end and an open proximal end, and defining an interior space configured to receive the residual limb. A one-way valve is positioned within the closed distal end and provides controlled fluid communication between the interior space and an external environment. The one-way valve may be configured to allow the weight of a user, via the residual limb, to expel moisture and air from the interior space out to the external environment.

A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of metalloprotease (TIMP) inducing activity, and immediate and delayed antioxidative activity. Preferably, the topical composition comprises at least one MMP inhibitor, a TIMP inducing agent, Tremella fuciformis (snow fungus) extract, Camellia sinensis (green tea) leaf extract, and Eugenia caryophyllus (clove) extract. The compositions are useful in anti-wrinkle and anti-aging products, providing elasticity, firmness, tone and texture to the skin, ameliorating fine lines and preventing skin damage.

The device is a thin, self-adhesive non-stretch splint, having the capability to flex. This device is intended for the treatment of repetitive stress injuries such as Carpal Tunnel Syndrome with elements that provide user adjustable limitation of movement within acceptable medical parameters. Carpal Tunnel Syndrome symptoms include pain and numbness in the thumb, index, and middle fingers, that are aggravated by compression of the median nerve. This device limits flexion, extension, ulnar and radial deviation movements of the wrist without compressing the median nerve The device limits movement by reducing skin elasticity on the surface skin above or below the wrist and up the forearm. The application provides biomechanical feedback to the wearer in the form of the tugging sensation on the skin around the perimeter of the device assisting the user in maintaining a more neutral wrist position without imposing wrist immobilization. The design elements allow the use of the device in such a manner that produces no additional pressure to the median nerve while in use. Furthermore the method of application provides a means for the user to regulate the amount of wrist movement to provide a greater comfort level while still limiting movement within medically proven parameters. The adhesive nature of the device eliminates the need for external straps that normally wrap completely around the forearm and hand to hold a splint in place. The application of the device limits movement by greatly reducing the ability of the skin to stretch by placing a self-adhesive non-stretch splint directly on the skin. The device, and how it is placed utilizes the wearers skin elasticity to provide biomechanical feedback to the user to promote better wrist posture.

A multi-layer patient support element comprising at least one structural member, wherein the structural member has a top surface and a bottom surface and wherein the top surface comprises a low radiation absorbing separation member. The support element of the present invention can be integrated into a patient support surface, used as an insert or easily removable from the patient support surface. The support element can reduce or eliminate radiation skin burn caused during radiation therapy.

The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.

A pull-on disposable wearing article is provided with a chassis and an absorbent batt structure extending on the inner surface of the chassis. The chassis has a front waist region, a rear waist region and a crotch region and is composed of a base sheet which is substantially not elastically extensible/contractible, and first and second outer sheets stretched in a transverse direction and bonded in such a stretched state to outer surfaces of the base sheet in the front and rear waist regions, respectively, and being elastically extendible/contractible in the transverse direction. An absorbent batt structure is laid inside the chassis. The base sheet defining an inner surface of the chassis is formed with gathers as the first and second outer sheets contract.

A method of producing a population of differentiated cells comprising: a) inducing differentiation in a first population of cells by applying an inducer to said cells, b) harvesting microvesicles produced from first population of cells, and c) inducing differentiation in a second population of cells by applying said microvesicles or a derivative thereof to said second population of cells wherein, said first population of cells is autologous to said second population of cells and wherein the inducer applied to said first population of cells is not present in said second population of cells or is only present in trace amounts. Also related methods of producing microvesicles, methods of medical and/or cosmetic treatment and related products and uses.

The invention provides a subsea pressure boosting system feasible for operation at subsea step out lengths above 40 km and by control merely from a dry topside or onshore location. The system is distinctive in that it comprises: at least one subsea power step out cable, arranged from a near end at a dry location onshore or topsides to one or more subsea loads such as subsea pumps or subsea compressors at a far end, at the near end at least one source for electric power is connected and the cable is dimensioned for operation at a frequency different from the operation frequency of the connected subsea loads in order to handle the Ferranti effect and electric losses, and at least one passive electric frequency transformer, operatively connected between the subsea step out cable far end and the subsea loads, said transformer is located in a pressure vessel and transforms the operation frequency of the subsea step out cable to a frequency feasible for operation of the connected loads.