The invention belongs to the field of skin-care products, and provides a whitening, acne-removing, blackhead-removing and anti-aging composition, and an application and a preparation thereof. The composition provided by the invention has whitening, acne-removing, blackhead-removing and anti-aging efffects, can inhibit the expression of inflammatory factors, namely IL-1 and TNF-a at the same time,reduces the effect of androgen dihydrotestosterone, and has the advantages of no drug resistance and no side effect compared with hormone for treatment.