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267results about How to "The mechanism of action is clear" patented technology

A leaven dedicated for fermenting bed of microorganism engineering and fermenting bed pad manufacture method

The invention relates to a leaven dedicated for fermenting bed of microorganism engineering constituting in weight ratio: Lactobacillus of 15%-25%, enterococcus of 15-30%, yeast of 5-15%, bacillus subtilis of 10-30%, Bacillus licheniformis of 5-20%, Lactobacillus sporogenes of 5-20%; total live microbe being 5-10 hundred million / g. The leaven of the invention is composed of biotic bacteria with strong activity, and has definite composition and mechanism, and stable product quality, and good health effect for improving immunity of the animal and preventing disease, strong degradation ability for pig manure; the leaven can not degrade material of fermenting bed pad, can prolongs life of fermenting bed; the fermenting bed can be conveniently and simply manufactured, which saves more than 80% of labor.
Owner:北京好友巡天生物技术有限责任公司

Solid beverage having assisted blood glucose lowering function, and preparation method thereof

The invention relates to a solid beverage having an assisted blood glucose lowering function, and a preparation method thereof, wherein the main function components are three or more than three materials selected from kelp or a kelp extract, potassium alginate (low molecular weight potassium alginate), common yam rhizome or a common yam rhizome extract, Chinese wolfberry or a Chinese wolfberry extract, radix puerariae or a radix puerariae extract, mulberry leaf or a mulberry leaf extract, a polygonatum odoratum extract, a bitter gourd extract, the leaf of cyclocarya paliurus and corn stigma, the auxiliary materials comprise one or more than one materials selected from inulin, resistant dextrin, bean powder, tea powder, pumpkin powder, soybean protein powder, barley leaf powder, oat fiber powder, konjac powder and citrus fiber powder, and the flavoring agent is one or a plurality of materials selected from stevioside, xylitol, fructo oligosaccharide, isomaltitol, sucralose, trehalose, matcha powder, and fruit and vegetable powder. The preparation method comprises: 1, crushing, and screening; 2, weighing; 3, carrying out mixing stirring, or carrying out stirring mixing and granulation; and 4, packaging. The solid beverage of the present invention has advantages of significant blood glucose lowering effect, good safety, and no side effect.
Owner:DALIAN YAWEITE BIOTECH

Indigenous microorganism activation and exogenous microorganism intensified oil production method in offshore oilfield

The invention relates to an indigenous microorganism activation and exogenous microorganism intensified oil production method in an offshore oilfield, which belongs to the technical field of producible oil index improvement, and includes the following steps: firstly, preparation of exogenous microorganism bacterial liquor: beneficial microorganisms separated from an oil deposit stratum are subjected to enrichment culture; secondly, preparation of indigenous microorganism activators: the mass percent of components are: 0.25%-0.5% byproduct molasses in sugar industry, 0.1%-0.2% byproduct corn steep liquor of corn starch, 0.2%-0.4% sodium nitrate and 0.1%-0.3% phosphate; and thirdly, underground activation of an indigenous microflora: the following stages are included: the first stage, exogenous microorganism bacterial solution is injected to improve amount of functional microorganisms and provide nutrition substrates for growth of anaerobic bacteria, and the second stage, indigenous microorganism activators are injected in the anaerobic part of a stratum to improve the oil recovery efficiency. The method has the advantages of simplicity in operation, strong suitability, no harm to an oil-bearing sand, zero pollution, improved recovery efficiency and the like.
Owner:E TECH ENERGY TECH DEV CORP

Method for directionally regulating and controlling indigenous microbial flooding of oil reservoir

The invention relates to a method for directionally regulating and controlling indigenous microbial flooding of an oil reservoir and belongs to the technical field of improvement on crude oil recovery rate. The method for directionally regulating and controlling the indigenous microbial flooding of the oil reservoir is characterized by comprising the following steps of: firstly, activating hydrocarbon oxidizing bacteria of a near wellbore zone; injecting an aerobic system activation agent into the near wellbore zone; directionally activating the hydrocarbon oxidizing bacteria of the near wellbore zone; and secondly, activating anaerobic fermentation bacteria at the deep part of the oil reservoir, injecting an anaerobic system activation agent into the deep part of the oil reservoir, directionally activating the anaerobic fermentation bacteria, activating methanogen to generate gas by using metabolite of the anaerobic fermentation bacteria and improving the crude oil recovery rate through beneficial metabolic products of microorganism. The method disclosed by the invention has the advantages of simple process, directional activation, convenience in operation, low cost, economy, practicability, no toxicity, no harm, no nutrient waste, wide application range, facilitation for large-scale application of a mine filed and the like.
Owner:E TECH ENERGY TECH DEV CORP

Polypeptide composition capable of resisting oxidation and inhibiting melanin synthesis and application thereof

The invention provides a polypeptide composition. The polypeptide composition comprises a composition of one or more polypeptides with anti-oxidization effect and one or more polypeptides with the effects of inhibiting melanin synthesis; and mass concentration of each polypeptide component is 0.0001%-5%. The composition is mainly used for improving and preventing skin ageing and yellowish skin caused by oxidization, so that the purposes of improving skin hyperpigmentation, improving yellowish skin and lightening skin are achieved; and various skin diseases, such as lupus erythematosus and polymorphous light eruption, caused by oxidative damage are prevented.
Owner:SHENZHEN WINKEY TECH CO LTD

Total triterpene of garden burnet root with anti-inflammatory and analgesic effects and preparation method thereof

The invention belongs to the technical field of medicaments, and provides a method for preparing total triterpene of Chinese medicament garden burnet root. The total triterpene is mainly obtained by performing reflux extraction by 70 percent ethanol, absorbing by a macroporous absorbent resin, using water to wash off impurities, using ethanol solution for elution, then decolorizing an eluent by daiamid powder, using the ethanol solution for elution, and recovering the ethanol through pressure reduction. The total triterpene mainly contains triterpenic acid active components such as arjunic acid, 1beta-euscaphic acid, euscaphic acid, tormentic acid and the like, and triterpenoid saponin active components such as sanguisorbin I, sanguisorbin II, sanguisorbin III, niga-ichigoside, kaji-ichigoside F1 and the like. Experimental results show that the total triterpene has remarkable anti-inflammatory and analgesic effects. The total triterpene has definite action substance basis and action mechanism as well as simple preparation technology, is suitable for industrialized production, can be taken as medicinal raw materials for treating inflammatory diseases such as burn and scald, rectitis, ulcerative colitis, pyelonephritis and the like, and is prepared into clinically acceptable dosage forms such as tablets, capsules, granules or compound preparations according to the prior process.
Owner:SHENYANG PHARMA UNIVERSITY

Proteoglycan isolated from cartilaginous fish and process for producing the same

It is intended to provide a cartilage extract which exerts its effect even in the case of taking in a small amount and shows a definite function mechanism of the effect. Namely, isolated proteoglycan which originates in a water extract of the cartilage of a cartilaginous fish and the main component of which has a molecular weight of 500 kDa or higher; a composition containing this proteoglycan; a medicinal composition containing the proteoglycan as the active ingredient; and a process for producing the proteoglycan which comprises the step of grinding the cartilage of a cartilaginous fish into pieces of an average diameter of 100 mum or less, the step of adding water to the ground matter and extracting water-soluble components therefrom, the step of separating the aqueous phase containing the water-soluble components, and the step of adding an alcohol to the aqueous phase and obtaining the precipitate.
Owner:HOSOKAWA MICRON CORP

Health-care food for regulating blood fat and comprehensively antagonizing atherosclerosis and preparation method thereof

The invention belongs to health-care foods for regulating blood fat and comprehensively antagonizing atherosclerosis, in particular to a health-care food for regulating blood fat and comprehensively antagonizing atherosclerosis with high safety performance, remarkable effect and stable and accordant quality control and a preparation method thereof. The health-care food is prepared from the following raw materials in parts by weight: 10 to 35 parts of functional monascus red powder, 1 to 10 parts of pueraria isoflavones powder, 1 to 8 parts of isoflavone powder, 1 to 8 parts of bamboo leaf flavone powder, 1 to 8 parts of resveratrol powder, 1 to 6 parts of hawthorn powder, 1 to 6 parts of rhizoma gastrodiae powder, 1 to 30 parts of black fungus powder, 0.1 to 2 parts of seahorse powder, 0.008 to 0.04 part of astaxanthin powder, 0.1 to 0.3 part of menthol powder, and 20 to 50 parts of resistant starch. The health-care food has the advantages of mild medicine property, delicious taste, and no toxicity, safety, fixed content of effective components, remarkable effect, controllable quality, stable action and long term edibility, and is all natural.
Owner:万光瑞

Skin aging resistance traditional Chinese medicine cosmetic and preparation method thereof

The invention relates to a skin aging resistance traditional Chinese medicine cosmetic composition, which is prepared by adding three traditional Chinese medicine extracts such as a ginseng extract, a dendrobium extract and clove volatile oil to a cosmetic matrix. The production method comprises: heating the three traditional Chinese medicine extracts to a temperature of about 80 DEG C, and then mixing the heated three traditional Chinese medicine extracts and a pretreated cosmetic matrix to prepare the traditional Chinese medicine cosmetic. According to the present invention, percutaneous penetration experiment results show that ginsenosides (Rg1, Rb1 and Re) having definite anti-oxidation and aging delaying effects and eugenol in the series of the traditional Chinese medicine cosmetic can penetrate through skin, and the clove volatile oil is adopted as the permeation promoter so as to increase the permeation amount of the ginsenoside components; and with the percutaneous penetration experiment, the material basis assurance is provided for provision of treatment effects of various effective components after entering skin.
Owner:SHANTOU YANA COSMETICS IND CO LTD

Researching and preparing method for new Chinese medicine

InactiveCN1473583AEasy to identifyOptimize the matching ratioUnknown materials
The Chinese medicine developing process includes selecting traditional Chinese recipe with determined curative effect, separating the components, optimizing the component combination, determining thescreening model and performing medicine effect test based on Chinese medicinal theory and compound Chinese medicine features, computer aided analysis to recognize effective components, combining modeand medicinal effect, and optimizing new Chinese medicine. The said process can raise the screening efficiency of effective components, shorten screening period and embody compound Chinese medicine features. Altering the combination mode of medical herb pieces into combination of effective components develops modern Chinese medicine preparation with clear matter basis and controllable quality, being safe and effective and coinciding with international standard.
Owner:ZHEJIANG UNIV

Health-care food for assisting blood glucose decreasing and preparation method of granule and capsule thereof

The invention discloses health-care food for assisting blood glucose decreasing. The main functional components of the health-care food are three or more than three types of the following raw materials: kelp or kelp extract, potassium alginate (low molecular weight potassium alginate), rhizoma dioscoreae or rhizoma dioscoreae extract, lycium Chinense miller or lycium Chinense miller extract, radix puerariae or radix puerariae extract, folium mori or folium mori extract, rhizoma polygonati odorati extract, momordica charantia extract, cyclocarya paliurus leaf, corn stigma, rhizoma polygonati, radix astragali seu hedysari, radix notoginseng or radix notoginseng extract, rhodiola rosea or rhodiola rosea extract, inulin and citrus fiber powder. A preparation method of the health-care food for assisting the blood glucose decreasing comprises the following steps of 1, crushing and screening; 2, weighing; 3, mixing and stirring. The health-care food for assisting the blood glucose decreasing has the advantages that the effect of assisting blood glucose decreasing is obvious, the safety is good, any side effect is avoided, and complications and side effects caused by long-time administration of western blood glucose decreasing medicines are avoided; the administration is convenient, and the carrying is easy; the action mechanism is clear, the economic and practical effects are realized, and the application range is wide.
Owner:DALIAN YAWEITE BIOTECH

Anti-mud small material for compounding of polycarboxylate superplasticizer and application method thereof

The invention discloses an anti-mud small material for compounding of a polycarboxylate superplasticizer and an application method thereof. The anti-mud small material is prepared from the following raw materials by mass: 60 to 75% of sodium pyrosulfite, 0 to 20% of sodium hexametaphosphate, 10 to 25% of sodium tripolyphosphate and 5 to 15% of sodium nitrate. A preparation method for the anti-mud small material is to uniformly mix the above-mentioned raw materials in proportion under stirring and hermetically preserve the obtained anti-mud small material. According to the application method, the anti-mud small material is used as a compounding small material for compounding with the polycarboxylate superplasticizer, and the usage amount of the anti-mud small material is 1 to 5% of a finished polycarboxylate superplasticizer product. According to the invention, the anti-mud small material has strong clay dispersion capability and preferential clay adsorption effect, thereby greatly reducing adsorption consumption of the polycarboxylate superplasticizer by clay, guaranteeing high water-reducing effect and excellent slump loss resistance of the polycarboxylate superplasticizer and offsetting influence of the clay on concrete strength; and the preparation and application methods are simple, the usage amount of the anti-mud small material is small, and cost is low.
Owner:GUIZHOU TIEJIANHENGFA NEW MATERIAL TECH CO LTD

Prepn process and recipe of composite nano emulsion containing coix seed oil and java brucea fruit

The composite nano preparation with determined anticancer effect includes coix seed oil, java, brucea fruit oil, bean phospholipid, pure glycerin and injectino water, which are prepared into composite emulsion, composite nanometer emulsion, liposome and powder for injectino for intravenous injection, oral taking, perfusion, etc. separately. Each 100 ml of the emulsion for injectino contains coix seed oil 5.0-15.0g, java brucea fruit oil 5.0-15.0 g, bean phospholipid 0.8-1.6 g and pure glycerin 2.0-3.0 g except injection water. The emulsion for injectino has grain size in the range of 0.1-0.8 micron. The coix seed oil and jave brucea fruit oil in the said preparations are extracted through supercritical SFECO2 extracting process and refined to reach the standard for injection.
Owner:SHENYANG YAODA MEDICINE DEV +1

Method for controlling crack of super-long wall body

The invention relates to a method for controlling a crack of a super-long wall body. The method is characterized by comprising the following steps: the super-long wall body is vertically divided by a thin steel plate along the longer inner core concrete of the wall; then a water stop steel plate is arranged on the axial position vertical to a separation steel plate; the separation steel plate divides the water stop steel plate into two parts and leads the two parts to be vertical to each other; and the separation steel plate and the water stop steel plate are positioned between meshes reinforcement at two sides of the wall body, and are bound and fixed with the meshes reinforcement. Compared with the prior art, the method for controlling the crack of the super-long wall body has simple and clear construction procedure, is advantageous to reduction of shrinkage stress of the wall body, can effectively play a role in controlling the crack matched with prestressed reinforcement, can be applied to any wall body structure requiring crack control, in particular to construction of the wall body of an underground garage, the side wall plates of overground and underground artificial channels, a super-long large water pool, side wall of a sewage treating pond and a retaining wall.
Owner:NINGBO CONSTR +2

Injection liposome microball containing ketoprofen or ketoprofen ester and its preparing process

InactiveCN1709232AIncrease fat solubilitySignificant analgesic and anti-inflammatory effectsOrganic active ingredientsLipid formationMicrosphere
The present invention relates to a lipid microsphere injection containing ketoprofen or ketoprofen ester, its preparation process and prescription. It has good action for stopping pain, resisting inflammation and reducing fever. Said lipid microsphere includes ketoprofen or one ketoprofen ester, injection soybean oil, injection medium chain triglyceride, phospholipids, pure glycerin and injection water. Said invention can be used for preparing pain-stopping and inflammation-relieving medicine.
Owner:SHENYANG PHARMA UNIVERSITY

Efficient soothing anti-allergy repair polypeptide composition and application thereof

The invention discloses an efficient soothing anti-allergy repair polypeptide composition and an application thereof. The efficient soothing anti-allergy repair polypeptide composition provided by theinvention comprises acetyl heptapeptide-4, oligopeptide, palmitoyl tripeptide-8, palmitoyl tetrapeptide-7, heptapeptide-6, 10-30% of butanediol, glycerol, water, carbomer and sodium lactate, and a pHrange is 4.0-6.0. The polypeptides in the composition can have effective synergistic effects, and compared with a single polypeptide and a combination of part of the polypeptides in the composition,the polypeptide composition has more effective anti-allergy repair effects and shows obvious synergistic effects. The anti-allergy repair polypeptide composition covers three aspects of a skin sensitivity forming mechanism, has a brand-new barrier repair mechanism, effectively regulates and controls sensory nerve overreaction and reduces inflammatory aging, and therefore is an ideal and comprehensive anti-allergy repair product.
Owner:ZHEJIANG PEPTITES BIOTECH CO LTD

Critical burial depth computing method for groundwater recharging vegetation

The invention relates to a critical burial depth computing method for a groundwater recharging vegetation. The critical burial depth computing method comprises the following steps: collecting data; establishing a rule model of known soil; computing effective aperture; computing the maximum lifting height of tubular billet water; computing the critical burial depth of the groundwater recharging vegetation. Through analyzing the functional relationship between underground water and a vegetation root system, the computing method elaborates the physical process of the groundwater recharging surface vegetation and defines the critical burial depth of the groundwater recharging surface vegetation; by taking the thickness of a diving activity layer and the thickness of the vegetation root layer as the computing goal, the determined critical burial depth computing method for a groundwater recharging surface vegetation is structured, and thus the technical blank is filled. The method has clear physical process and function mechanism, and also has the technical university for the vast arid region and semi-arid region; besides, the method provides reliable theoretical and technological supports for the reasonable development and utilization of underground water resource and water containing layer of underground water.
Owner:CHINA INST OF WATER RESOURCES & HYDROPOWER RES

Amphipathic conjugate anti-tumor nano-drug with function of reversing multidrug resistance of tumors and preparation method and application thereof

The invention discloses an amphipathic conjugate anti-tumor nano-drug with the function of reversing multidrug resistance of tumors. An anti-tumor drug is in covalent linkage with a P-gp protein inhibitor quinine by a coupling agent to form amphipathic conjugate, and the amphipathic conjugate is self-assembled under water, so as to obtain the amphipathic conjugate anti-tumor nano-drug. The invention also discloses a preparation method and application of the amphipathic conjugate anti-tumor nano-drug. Compared with the prior art, the amphipathic conjugate disclosed by the invention can be self-assembled in water to form the anti-tumor nano-drug, and does not need any drug carrier, thereby realizing common delivery of the P-gp protein inhibitor and the anti-tumor drug; after the anti-tumor nano-drug enters multidrug resistance tumor cells, linking groups are fractured under a microenvironment condition in tumor cells, and the anti-tumor drug and the P-gp protein inhibitor are released out and generate the synergistic effect, thereby effectively killing the tumor cells and the multidrug resistance tumor cells and hopefully improving the treatment effect of the tumors and multidrug resistance tumors.
Owner:SHANGHAI JIAO TONG UNIV

Chinese medicinal alcoholism relieving health-care beverage and preparation method thereof

InactiveCN102038260AExact content of medicinal ingredientsThe mechanism of action is clearFood preparationAstaxanthinPueraria lobata isoflavone
The invention belongs to the field of alcoholism relieving beverage, in particular to Chinese medicinal alcoholism relieving health-care beverage with high safety, high drug effect, stable and consistent quality control and acute and chronic alcoholism resistance, and a preparation method thereof. The beverage is prepared from the following raw materials in part by weight: 0.1 to 2 parts of pueraria flavonoid powder, 0.1 to 1.5 parts of bamboo flavonoid powder, 0.1 to 1.5 parts of semen hoveniae extract powder, 0.05 to 0.2 part of silymarin powder, 1 to 4 parts of gastrodia elata powder, 1 to 6 parts of fig powder, 0.1 to 1 part of algin powder, 0.01 to 0.2 part of menthol powder, 0.008 to 0.2 part of astaxanthin powder, 15 to 30 parts of resistant starch, and 69.8 to 184.8 parts of purified water. The Chinese medicinal alcoholism relieving health-care beverage has the advantages of mild medicinal property, delicious taste, pure nature and safety, definite content of effective ingredients and quick and remarkable drug effect, stable and consistent quality control and long term administration.
Owner:万光瑞

Method for calculating critical burying depth of rainfall infiltration recharged groundwater

The invention relates to a method for calculating critical burying depth of rainfall infiltration recharged groundwater. The method comprises the steps of: calculating saturated infiltration depth; calculating non-saturated infiltration depth based on the saturated infiltration depth; calculating the wetting front moving speed in a layer through hydraulic conductivity; judging whether the moving speed is greater than zero; calculating the moisture content of soil; calculating non-saturated infiltration depth; and calculating infiltration depth. According to the method, an action mechanism of the rainfall infiltration recharged groundwater is analyzed, a physical process of the rainfall infiltration recharged groundwater is explained, and the critical burying depth of the rainfall infiltration recharged groundwater is defined; a saturated and non-saturated infiltration theory is adopted, the wetting front moving distance is taken as a calculation target, and a rainfall infiltration depth calculation model is constructed for determining the critical burying depth of the groundwater. The method is clear and definite in physical process and action mechanism, has universality for damage on a reproducible mechanism caused by groundwater overdraft, and provides reliable theoretical and technical support for guiding groundwater resources to be reasonably developed and utilized and protecting groundwater aquifers.
Owner:CHINA INST OF WATER RESOURCES & HYDROPOWER RES

Soil salinization critical groundwater depth calculation method

The invention relates to a soil salinization critical groundwater depth calculation method. The method comprises the steps that a soil type is determined; soil texture is determined; a soil capillaryequivalent pore diameter is calculated; a temperature range is determined; surface tension of water is determined; a salinization critical value is determined; and critical depth is calculated. According to the method, by analyzing the principle that salt is brought to the surface under the action of groundwater capillaries, the soil salinization process is elaborated, and the critical depth causing soil salinization is defined; and a calculation function of a key parameter, namely the soil equivalent pore diameter, in a rise height theoretical formula of capillary water is derived, the maximum rise height of the capillary water is used as a calculation objective, and a salinization model is constructed to determine the soil salinization groundwater critical depth. The method is clear in physical process and action mechanism, has universality for solving the soil salinization problem caused by excessively high groundwater and provides reliable theoretical and technical support for guiding reasonable development and utilization of groundwater resources and governance of soil salinization.
Owner:CHINA INST OF WATER RESOURCES & HYDROPOWER RES

Dog-bone joint beam end buckling constraining device

ActiveCN106593059AGive full play to the excellent energy consumption performance of dog-bone nodesImprove energy consumptionProtective buildings/sheltersShock proofingBones jointsEngineering
The invention provides a dog-bone joint beam end buckling constraining device. The device comprises constraining cover plates (1), constraining U-steel (2), filling plates (3) arranged between the constraining cover plates and the constraining U-steel, and connecting bolts (4), wherein the constraining cover plates (1) are arranged on the outer sides of upper and lower flange weakening parts (7-1) at the ends of a steel beam (7) provided with a dog-bone joint; the constraining U-steel (2) is arranged on the portions, corresponding to the two sides of a web, of the flange weakening parts; and the connecting bolts (4) are used for connecting the constraining cover plates, the constraining U-steel and the filling plates to form the complete constraining device. When an earthquake occurs, the beam end flange weakening parts yield in advance of other parts and components, earthquake energy is dissipated through the hysteretic characteristic, and by adoption of the constraining device, press on the beam end flange weakening parts and large-amplitude buckling possibly occurring outside the plane of a steel plate when the corresponding web is pressed and sheared can be limited, shortening of the fatigue lives of the flange weakening parts and degradation of joint rigidity and strength are prevented, the steel beam (7) in a joint area is protected against complete buckling outside the plane, the fullness of a hysteretic curve is ensured, and the joint deformation capacity and ductility and the lateral stability of the beam are improved.
Owner:SOUTHEAST UNIV

Ductile coupling beam swinging steel frame system

The invention belongs to the technical field of civil engineering aseismic structural systems, and provides a ductile coupling beam swinging steel frame system. According to the ductile coupling beamswinging steel frame system, steel supporting frames composed of frame beams, frame columns and steel supports bear the vertical load, the lateral rigidity and resilience are provided, and the elasticity is maintained all the time by allowing the bottoms of the steel columns to rise under the action of an earthquake; seismic energy is dissipated through replaceable connecting beams and swinging type column feet, wherein the steel supporting frames on the left side and right side are connected through the replaceable connecting beams, and the bottoms of the frame columns adopt the swinging typecolumn feet; when a structural system is subjected to the seismic action, the seismic energy is dissipated by the replaceable connecting beams and the swinging type column feet, and the steel supporting frames on the two sides are prevented from being damaged; and the concept of the structural system is clear, design is simple, the action mechanism is clear, the replaceable connecting beams and the swinging type column feet are used as energy dissipation elements and connected with steel columns through bolts, input energy is dissipated in the earthquake, and after the earthquake, the purposeof quick recovery of the use function of the structure system can be achieved by replacing an energy dissipator.
Owner:DALIAN UNIV OF TECH

Five pancreatic lipase inhibitors derived from small red bean protein and application thereof

ActiveCN114805483ASignificant lipid-lowering effectAchieve lipid-lowering effectPeptide/protein ingredientsMetabolism disorderPancrelipaseEfficacy
The invention provides a peptide with a pancreatic lipase inhibitor effect. The sequence of the peptide is selected from SEQ ID NO.1-5; the invention also provides application of the peptide in preparation of medicines, foods and health-care products for treating hyperlipemia. The peptide is a plant-derived, non-toxic and harmless natural substance, and experiments prove that the peptide has remarkable pancreatic lipase inhibitory activity and lipid-lowering effect; the compound is clear in action mechanism and definite in target spot, is expected to become a substitute medicine for preventing and treating hyperlipemia, and has a good market prospect in the industries of medicine and functional food.
Owner:CHINA AGRI UNIV

Medicament for treating infectious diseases, preparation method and application thereof

The invention provides a medicament for treating infectious diseases, a preparation method and the application thereof. The medicament is prepared from scutellaria baicalensis, jasmine, erigeron breviscapus and cholic acid, and has the following effects: by aiming at the central link--inflammatory reaction of an infectious disease, removing harmful substances such as inflammatory mediators, free radicals and the like, and improving the local microcirculation state, thereby alleviating the pathological damages caused by inflammations; meanwhile, the medicament has the function of regulating the overall internal environment, and can effectively treat lower respiratory tract infection and acute lung injury induced by infection; and the effective substances and functional mechanism of the medicament are relatively clear.
Owner:KANGMEI PHARMA

Coastal glehnia root extract with function of antagonizing gastric ulcer and its prepn

The present invention belongs to the field of medicine technology, and is especially Chinese medicinal material coastal glehnia root extract and its preparation process. The preparation process includes the main steps of water extraction, alcohol precipitation, macroporous resin adsorption, water washing and alcohol solution eluting. The extract contains three kinds of active component, including lignan glycoside, coumarin glycoside and cinepazid glycoside, and includes 21 kinds of compound, including glehlinoside A, bergaptol 5-O-beta-D-gentiobioside, etc. It has obvious effects of antagonizing gastro ulcer, resisting oxidation and relieving pain, and is used as material of medicine for treating gastric ulcer and chronic gastritis.
Owner:SHENYANG PHARMA UNIVERSITY

Topical pharmaceutical composition of phosphodiesterase-4 inhibitor and preparation method thereof

The invention discloses a topical pharmaceutical composition of a phosphodiesterase-4 inhibitor and a preparation method thereof, wherein the topical pharmaceutical composition comprises 0.5 to 10% bymass of apremilast active ingredient, 0.2 to 25% by mass of dimethyl sulfoxide and 65 to 99.3% by mass of a topical pharmaceutical acceptable carrier. The dosage forms of the topical pharmaceutical composition are ointments, creams, gels, coatings, lotions, tinctures, powders and liniments. The invention also discloses the preparation method of the topical pharmaceutical composition and use of the topical pharmaceutical composition. The pharmaceutical composition is not like hormonal drugs which have the side effects to cause adermotrophia after long time of use, and the pharmaceutical composition has no disadvantages such as recurrence after curing, has desired pharmacological activity and less side effects, is stable in quality and convenient to use, is safe and effective in treatment of eczema, and has strong practical application value.
Owner:ZHAOKE PHARMA GUANGZHOU

Traditional Chinese Medicine extract against SARS virus

The present invention discloses one kind of rhubarb anthraquinone compound separated and extracted from rhubarb and with powerful SARS virus inhibiting effect. Extracorporeal experiment shows that the compound has SARS coronavirus 3C-like proteinase inhibiting rate over 85 % when the medicine dosage is 100 microgram / ml. In addition, the present invention has the features of clear medical speciality of rhubarb, rich medicine resource, clear rhubarb anthraquinone compound structure, determined acting mechanism and mature extraction process, and is significant in developing high efficiency and low toxicity SARS virus resisting medicine.
Owner:GUILIN MEDICAL UNIVERSITY

Dietary fiber composition for targeted improving of metabolism syndromes

ActiveCN108720030AEnhanced Health GainsIncrease supplyFood ingredient functionsCelluloseXylan
The invention belongs to the technical field of food science, and particularly relates to a dietary fiber composition for targeted improving of metabolism syndromes. According to the dietary fiber composition, xylan and mannan are used as basic components, and an appropriate amount of levan, an appropriate amount of pectin, and an appropriate amount of cellulose are added, so that the dietary fiber composition is prepared. The dietary fiber composition comprises the following components of xylan, mannan, levan, pectin and cellulose, wherein the weight ratio of the xylan to the mannan to the levan to the pectin to the cellulose is (5-90) to (5-90) to (5-90) to (0.01 to 70) to (0.01-70). The prepared dietary fiber composition can effectively improve various symptoms of metabolism syndromes,and can delay the disease processes. The dietary fiber composition is clear in action mechanisms, and clear in target treatment for diseases. The dietary fiber composition can clearly show clear and positive effects on many respects of reducing cholesterol, reducing blood sugar, reducing blood pressure and the like through human body experiment, and eaters can obtain clear and remarkable health gains which cannot be realized by a dietary fiber replenisher.
Owner:唐传生物科技(厦门)有限公司
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