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30 results about "Tormentic acid" patented technology
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Tormentic acid is a bio-active isolate of Luehea divaricata and Agrimonia eupatoria. Tormentic acid derivatives have been synthesized and researched.
Total triterpene of garden burnet root with anti-inflammatory and analgesic effects and preparation method thereof
InactiveCN101590134ASimple preparation processThe mechanism of action is clearAntipyreticAnalgesicsUlcerative colitisChronic pyonephrosis
The invention belongs to the technical field of medicaments, and provides a method for preparing total triterpene of Chinese medicament garden burnet root. The total triterpene is mainly obtained by performing reflux extraction by 70 percent ethanol, absorbing by a macroporous absorbent resin, using water to wash off impurities, using ethanol solution for elution, then decolorizing an eluent by daiamid powder, using the ethanol solution for elution, and recovering the ethanol through pressure reduction. The total triterpene mainly contains triterpenic acid active components such as arjunic acid, 1beta-euscaphic acid, euscaphic acid, tormentic acid and the like, and triterpenoid saponin active components such as sanguisorbin I, sanguisorbin II, sanguisorbin III, niga-ichigoside, kaji-ichigoside F1 and the like. Experimental results show that the total triterpene has remarkable anti-inflammatory and analgesic effects. The total triterpene has definite action substance basis and action mechanism as well as simple preparation technology, is suitable for industrialized production, can be taken as medicinal raw materials for treating inflammatory diseases such as burn and scald, rectitis, ulcerative colitis, pyelonephritis and the like, and is prepared into clinically acceptable dosage forms such as tablets, capsules, granules or compound preparations according to the prior process.
Owner:SHENYANG PHARMA UNIVERSITY
Method for producing triterpene composition
InactiveUS20050255569A1High purityEfficiently obtainedFermentationPlant cellsBiotechnologyAcetic acid
The present invention provides a method of producing a triterpene composition wherein callus induced from banaba, loquat, perilla or guava is cultured with indoleacetic acid and another plant hormone, and a triterpene composition containing at least one selected from the group consisting of corosolic acid, tormentic acid, 2α,19α-dihydroxy-3-oxo-urs-12-en-28-oic acid and maslinic acid is obtained from the cultured callus.
Owner:USE TECHNO CORP
Polyhydroxylated pentacyclic triterpene acids as hmg-coa reductase inhibitors
ActiveUS20150133552A1Lower serum cholesterol levelsReduce riskBiocideHydrocarbon active ingredientsDiseaseTormentic acid
The present invention relates to certain polyhydroxylated pentacyclic triterpene acids of formula (I) for use as HMG-CoA reductase inhibitors in the prophylactic and / or therapeutic treatment of a disease, disorder or condition that responds to a reduction of the HMG-CoA reductase activity in a mammal, preferably a human being. The present invention further relates to certain mixtures and plant extracts comprising euscaphic acid and tormentic acid, wherein the amount of euscaphic acid to tormentic acid exceeds a certain ratio. Further, the present invention also relates to a formulation, preferably pharmaceutical or nutraceutical formulation, comprising one or more of said compounds of formula (I), a composition according to the present invention or a plant extract according to the present invention. Also, the present invention relates to a process for obtaining certain polyhydroxylated pentacyclic triterpene acids of formula (I), a composition according to the present invention or a plant extract according to the present invention.
Owner:PRAIRIE BERRY EURO GMBH +1
Preparing method of loquat leaf total triterpenic acid and antidiabetic use thereof
The invention relates to a preparation method for triterpene acid of loquat leaf and the function of lowering the blood glucose. The preparation method comprises that dry loquat leaves are firstly extracted by ethanol or methanol with certain concentration, reclaimed in ethanol with low condensation for sedimentation, and centrifuged, precipitated and refluxing-decolorized with diatomite or done with chromatography with siliceous earth column, and then eluted with ethanol and reclaimed in condition of decompression and dried to obtain the triterpene acid of loquat leaf. Total content of ursolic acid, oleanolic acid, maslinic acid, corosolic acid and tormentic acid in the triterpene acid reaches more than 50 percent (by weight), wherein, the content of the tormentic acid is to be 10-30 percent, the maslinic acid 4-20 percent, the corosolic acid 5-20 percent, the oleanolic acid 1-10 percent and the ursolic acid 5-20 percent. The triterpene acid of loquat leaf prepared by the invention can be used for curing diabetes mellitus or preparing pharmaceutic preparations used for treating diabetes mellitus and diabetic complication.
Owner:INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
Application of triterpene compound and Parkinson's disease treatment medicine
ActiveCN106581006ANeuroprotectiveGood effectOrganic active ingredientsNervous disorderTormentic acidMedicine
The invention provides application of a triterpene compound and a Parkinson's disease treatment medicine. The application comprises blocking of mutual combination between autophagy skeleton protein Beclin1 and an autophagy inhibiting factor Bcl-2 so as to induce nerve cell autophagy, and preparation of a Parkinson's disease treatment medicine. The triterpene compound is any one or a mixture of two of maslinic acid and tormentic acid. The Parkinson's disease treatment medicine provided by the invention comprises a pharmaceutically acceptable auxiliary material as well as an effective dosage of any one or a mixture of two of the maslinic acid and the tormentic acid. The triterpene compounds, namely the maslinic acid and the tormentic acid, are capable of directly blocking mutual combination between the autophagy skeleton protein Beclin1 and the autophagy inhibiting factor Bcl-2, so that the triterpene compounds have the function of promoting autophagy in nerve cells, and have a nerve protection function on Parkinson's disease cells. Therefore, the maslinic acid and the tormentic acid can be directly adopted to prepare the Parkinson's disease treatment medicine, and the Parkinson's disease treatment medicine is endowed with good medicinal effect.
Owner:THE HONG KONG POLYTECHNIC UNIV SHENZHEN RES INST +1
Cherokee rose root fingerprint establishing method and cherokee rose root quality detection method
ActiveCN110455934AModerate heightSimple and fast operationComponent separationTest objectEuscaphic acid
The invention discloses a cherokee rose root fingerprint establishing method and a cherokee rose root quality detection method. According to the cherokee rose root fingerprint establishing method, cherokee rose root fingerprint can be obtained by preparation of a tested object solution and HPLC analysis detection. The establishing method is simple in operation, short in time for tested object solution preparation, high in precision, repeatability and stability, and accurate and reliable in detection, and includes more characteristic peaks. The cherokee rose root quality detection method can beused to detect quality of cherokee rose root medicinal materials, and provide high quality control standard for medicine production and detection, ensures the stability of product quality, and ensures that medicine use is safe and effective. Besides, contents of five important triterpene active components, including rosa roxburghii glycoside, multiflora rose glycoside, euscaphic acid and Chinesecinquefoil acid, which much influences the drug effect of cherokee rose root are detected and controlled to control the quality and effect of the cherokee rose root medicine.
Owner:ZHUZHOU QIANJIN PHARMA
Application of triterpenoid compound in preparation of antitumor medicines
InactiveCN104666306APrevent proliferationBlock cell cycleOrganic active ingredientsAntineoplastic agentsSide effectTormentic acid
The invention belongs to the field of biological medicines, and particularly relates to an application of a triterpenoid compound in preparation of antitumor medicines. A structural formula of the triterpenoid compound (tormentic acid) is shown in a formula I; and the tormentic acid is capable of obviously inhibiting proliferation of tumor cells, and significantly promoting apoptosis, so as to cause tumor cell death. The dosage of the tormentic acid is low; the toxic and side effects are lower than those of clinical common chemotherapeutic medicines; and the triterpenoid compound can be used as a novel anti-tumor medicine, is applied to treatment of tumors, and is simple in medication way and easy to operate.
Owner:SOUTH CHINA UNIV OF TECH
Method for inhibiting activity and/or expression of matrix metalloproteinase, inhibiting phosphorylation of mitogen-activated protein kinase, and/or promoting expression of collagen using tormentic acid
A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and / or promoting the expression of collagen in a mammal is provided. The method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof:
Owner:CHINA MEDICAL UNIVERSITY(TW)
Joint preparation method for euscaphic acid and tormentic acid
InactiveCN102391347ALarge amount of processingEasy to operateSteroidsHigh concentrationMacroporous resin
The invention belongs to the field of separation of natural products, and provides a joint preparation method for euscaphic acid and tormentic acid. The preparation method comprises the following steps of: extracting with an ethanol liquid; treating with macroporous resin; eluting sugars and other impurities with water and a low-concentration aqueous solution serving as a water-soluble organic solvent; eluting with a high-concentration aqueous solution serving as a water-soluble organic solvent; concentrating the eluent under reduced pressure to dryness to obtain a total triterpene extract; purifying with an efficient liquid phase preparative chromatograph; segmentally collecting an euscaphic acid fraction and a tormentic acid fraction; and thermally refluxing and crystallizing with methanol to obtain high-purity euscaphic acid and tormentic acid. A product prepared with the method has high product purity and good quality.
Owner:NANJING ZELANG MEDICAL TECH
Thymosin enteric-coated tablet and preparation method thereof
ActiveCN111297820ASolve the fluctuation of treatment effectGood treatment effectOrganic active ingredientsPeptide/protein ingredientsTormentic acidCoating drugs
The present invention relates to a thymosin enteric-coated tablet and a preparation method thereof. The thymosin enteric-coated tablet comprises thymosin, tormentic acid, a pharmaceutically acceptablecarrier, an enteric coating, and an optional absorption enhancer. The addition of the tormentic acid in the thymosin enteric-coated tablet can effectively solve a problem of fluctuation of release degrees of the thymosin in the intestine due to pH changes, also has a considerable promotion effect on activity of the thymosin, and further enhances an immune regulation effect.
Owner:H H T WHITE SWAN PHARMACY GRP
Application of tormentic acid to preparation of anti-anoxia medicine
InactiveCN106727604AImprove antioxidant capacityImprove respiratory functionOrganic active ingredientsNervous disorderTypes diseasesTormentic acid
The invention relates to application of tormentic acid to preparation of an anti-anoxia medicine and belongs to the technical field of medicine preparation. The medicine prepared by the invention has good clinical application prospect and the prepared anti-anoxia medicine can be used for treating anoxia type diseases.
Owner:LOGISTICS UNIV OF CAPF
Application of pawpaw total triterpene and components thereof in pharmacy
InactiveCN105213531AImproved morphologyIncrease x-enzyme activityOrganic active ingredientsDigestive systemDiclofenac SodiumUrsolic acid
The invention provides application of pawpaw total triterpene and components thereof (including oleanolic acid, ursolic acid, acetyl ursolic acid, betulinic acid, maslinic acid, acetyl pomolic acid and tormentic acid), including the following pawpaw total triterpene and components thereof or pharmaceutically acceptable salt, in medicines for treating digestive duct injury as active ingredients, wherein the digestive duct injury is caused by non-steroidal anti-inflammatory drugs. Results show that the pawpaw total triterpene and oleanolic acid, which is an important triterpene component, take a relatively good therapeutic effect on indometacin-caused mice gastric mucosal injury and diclofenac sodium-caused mice intestinal mucosa injury; therefore, an effective and safe medicine is provided for preventing and treating digestive duct injury due to use of NASIDs, and especially for preventing and treating peptic ulcer.
Owner:CHINA THREE GORGES UNIV
Application of 23-trans-para-coumaroyl tormentic acid compound
ActiveCN105104394AReduce pesticide residuesGood environmental compatibilityBiocideFungicidesNatural productPesticide residue
The invention discloses application of a 23-trans-para-coumaroyl tormentic acid compound. The structure of the compound is shown as a formula (I). The application has the advantages that the activity of borrytis cinerea can be effectively inhibited by the 23-trans-para-coumaroyl tormentic acid compound, the minimum inhibition concentration is 4 micrograms / mL, and the 23-trans-para-coumaroyl tormentic acid compound can be used as a novel pesticide component or a lead compound with a sterilization effect; the compound shown as the formula (1) is a botanical natural product and is low in toxicity and pesticide residue and excellent in environment compatibility, and the like.
Owner:SHANDONG XINGHE CROP SCI TECH CO LTD
Pharmaceutical composition for treating rhinitis, and preparation method of pharmaceutical composition
InactiveCN106619815AEffective treatmentOrganic active ingredientsPteridophyta/filicophyta medical ingredientsTormentic acidCurative effect
The invention discloses a pharmaceutical composition for treating rhinitis, and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following crude drugs: qingyangshengenin, bark of Japanese spicebush, herba neolepisori ovati, tormentic acid, cycloartanol and homoplantaginin according to a proportion. The pharmaceutical composition can be prepared into various preparations according to the conventional preparation technology, and is remarkable in curative effect when being used for treating the rhinitis.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Polyhydroxylated pentacyclic triterpene acids as HMG-COA reductase inhibitors
ActiveUS10047034B2Lower serum cholesterol levelsReduce riskBiocideEdible oils/fats ingredientsDiseaseTormentic acid
The present invention relates to certain polyhydroxylated pentacyclic triterpene acids of formula (I) for use as HMG-CoA reductase inhibitors in the prophylactic and / or therapeutic treatment of a disease, disorder or condition that responds to a reduction of the HMG-CoA reductase activity in a mammal, preferably a human being. The present invention further relates to certain mixtures and plant extracts comprising euscaphic acid and tormentic acid, wherein the amount of euscaphic acid to tormentic acid exceeds a certain ratio. Further, the present invention also relates to a formulation, preferably pharmaceutical or nutraceutical formulation, comprising one or more of said compounds of formula (I), a composition according to the present invention or a plant extract according to the present invention. Also, the present invention relates to a process for obtaining certain polyhydroxylated pentacyclic triterpene acids of formula (I), a composition according to the present invention or a plant extract according to the present invention.
Owner:PRAIRIE BERRY EURO GMBH +1
Medicine spray for treating rhinitis and preparation method thereof
InactiveCN109394916APlay a bactericidal effectImprove immune barrier functionHydroxy compound active ingredientsAntipyreticDiseaseBenproperine
The invention discloses a medicine spray for treating rhinitis and belongs to the technical field of medicine preparation. The medicine spray is prepared from the following raw materials in parts by weight: 20 to 32 parts of cynanchagenin, 15 to 33 parts of Japanese spicebush bark, 11 to 19 parts of tormentic acid, 8 to 12 parts of cycloartanol, 1 to 5 parts of homoplantaginin, 2 to 8 parts of clindamycin, 3 to 9 parts of capillarisin, 2 to 8 parts of glycyrrhizin, 3 to 7 parts of polygalic acid, 1 to 5 parts of synergists, 1 to 5 parts of acetone chloroform, 3 to 7 parts of sodium benzoate, 80 to 100 parts of distilled water, 2 to 10 parts of chlorine gluconate, 1 to 3 parts of paracetamol, 1 to 3 parts of benproperine, 1 to 5 parts of herb eriocaulon buergerianum and 2 to 8 parts of plant essential oil. The medicine spray has the advantages that the curative effect is obvious; no toxic or side effect exists; both symptoms and root causes can be treated; the treatment method is more reasonable; the exact curative effect can be achieved on relieving the disease and pain of rhinitis.
Owner:何凤姣
Pharmaceutical composition for preventing and treating senile osteoporosis
InactiveCN106581326AEffectively prevent and treat osteoporosis in the elderlyOrganic active ingredientsSkeletal disorderTormentic acidCurative effect
The invention discloses a pharmaceutical composition for preventing and treating senile osteoporosis and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared by proportioning the following medicinal raw materials: root of iris speculatrix hance, herb of oetrocosmea minor hemsl, limnaea, tormentic acid, euparotin and dihydromikanolide, and the pharmaceutical composition can be prepared into various dosage forms in accordance with a conventional preparation process. The pharmaceutical composition is significant in curative effect on preventing and treating the senile osteoporosis.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Traditional Chinese medicine active component composition for treating cough and preparation method thereof
PendingCN113197904AGood synergyGood for clearing away heatHydroxy compound active ingredientsAntipyreticPharmacometricsBULK ACTIVE INGREDIENT
The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine active component composition for treating cough and a preparation method thereof, the traditional Chinese medicine active component composition for treating cough comprises the following components by mass: 15-35 parts of tormentic acid, 15-25 parts of alpha-cedrol, 15-40 parts of beta-sitosterol, and 18-25 parts of ammonium glycyrrhizinate. The traditional Chinese medicine active component composition for treating cough provided by the invention is clear in pharmacodynamic material basis, is prepared by compatibility of tormentic acid, alpha-cedrol, beta-sitosterol and ammonium glycyrrhizinate, is clear in structure, fixed in component and controllable in quality, and lays a foundation for safety and effectiveness of the traditional Chinese medicine active ingredient composition; the action mechanism is clear, and by adopting a mode of combining classical pharmacology and systematic biological research, the stimulation to the cough center is reduced, so that the purpose of relieving cough is achieved; the composition disclosed by the invention can be used for improving the disorder of an antioxidant balance system in a body, effectively removing excessive free radicals in the body and relieving oxidative damage.
Owner:HETIAN UYGHUR PHARMA
Application of tormentic acid in preparation of medicine for treating or preventing Alzheimer disease caused by estrogen lack
ActiveCN105106222AImprove cognitive impairmentIncrease the number ofOrganic active ingredientsNervous disorderCholinergic cellsDuring menopause
The invention discloses application of tormentic acid in preparation of medicine for treating or preventing the Alzheimer disease caused by estrogen lack, and belongs to the technical field of tormentic acid medicine new application. According to the technical scheme, the application is characterized in that the molecular formula of the tormentic acid is C30H48O5, and the structural formula is as shown in specifications; the tormentic acid can improve the cognition impairment of an AD patient and increase the number of in-brain cholinergic neurons and has a neuron protection effect on CNS, wherein the protection effect can be achieved through ERalpha, and the result provides experimental bases for using the tormentic acid as a medicine select for treating menopause women in combination with AD.
Owner:XINXIANG MEDICAL UNIV
Medicine composition for treating neurodermatitis
The invention discloses a medicine composition for treating neurodermatitis and a preparation method thereof. The medicine composition is proportionally prepared by using tormentic acid, herbs of heterostemma oblongifolium and herbs of myriophyllum spicatum as active pharmaceutical ingredients. The medicine composition can be prepared into various dosage forms according to a conventional preparation process; the curative effect on treating neurodermatitis is obvious.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Pharmaceutical composition capable of preventing and treating cervicitis
The invention discloses a pharmaceutical composition capable of preventing and treating cervicitis and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared by taking Chinese viburnum stem, root of iris speculatrix hance, nerolidol, tormentic acid and caulis sargentodoxae as crude drugs and proportioning; the pharmaceutical composition can be prepared into various preparations according to a conventional preparation process and has the remarkable curative effect on prevention and treatment of the cervicitis.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Method for inhibiting activity and/or expression of matrix metalloproteinase, inhibiting phosphorylation of mitogen-activated protein kinase, and/or promoting expression of collagen using tormentic acid
InactiveUS20120059059A1Inhibitory activityHigh expressionCosmetic preparationsBiocidePhosphorylationTormentic acid
A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and / or promoting the expression of collagen in a mammal is provided. The method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof:
Owner:CHINA MEDICAL UNIVERSITY(TW)
Method for suppressing diabetes and/or hepatic lipids using tormentic acid
InactiveUS20170105953A1Suppressing diabetesLowering blood-glucoseOrganic active ingredientsLiver tissueTormentic acid
Provided is a method for suppressing diabetes and / or hepatic lipids in a mammal to lower blood glucose levels and hepatic total lipids and triacylglycerol contents by increasing AMP-activated protein kinase (AMPK) phosphorylation in both skeletal muscle and liver tissue, and Akt phosphorylation and membraneprotein levels of glucose transporter 4 (GLUT4) in skeletal muscle. The method comprises administrating to the mammal an effective amount of tormentic acid or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Owner:SHIH CHUN CHING
Total triterpene of garden burnet root with anti-inflammatory and analgesic effects and preparation method thereof
InactiveCN101590134BSimple preparation processThe mechanism of action is clearOrganic active ingredientsAntipyreticUlcerative colitisChronic pyonephrosis
The invention belongs to the technical field of medicaments, and provides a method for preparing total triterpene of Chinese medicament garden burnet root. The total triterpene is mainly obtained by performing reflux extraction by 70 percent ethanol, absorbing by a macroporous absorbent resin, using water to wash off impurities, using ethanol solution for elution, then decolorizing an eluent by daiamid powder, using the ethanol solution for elution, and recovering the ethanol through pressure reduction. The total triterpene mainly contains triterpenic acid active components such as arjunic acid, 1beta-euscaphic acid, euscaphic acid, tormentic acid and the like, and triterpenoid saponin active components such as sanguisorbin I, sanguisorbin II, sanguisorbin III, niga-ichigoside, kaji-ichigoside F1 and the like. Experimental results show that the total triterpene has remarkable anti-inflammatory and analgesic effects. The total triterpene has definite action substance basis and action mechanism as well as simple preparation technology, is suitable for industrialized production, can be taken as medicinal raw materials for treating inflammatory diseases such as burn and scald, rectitis, ulcerative colitis, pyelonephritis and the like, and is prepared into clinically acceptable dosage forms such as tablets, capsules, granules or compound preparations according to the prior process.
Owner:SHENYANG PHARMA UNIVERSITY
A kind of establishment method of golden cherry root fingerprint and quality detection method of golden cherry root
ActiveCN110455934BShort preparation timeGood precisionComponent separationBiotechnologyMedicinal herbs
Owner:ZHUZHOU QIANJIN PHARMA
Application of triterpenoids in the preparation of Parkinson's medicines
ActiveCN106581006BNeuroprotectiveGood effectOrganic active ingredientsNervous disorderMedicineTormentic acid
The invention provides application of a triterpene compound and a Parkinson's disease treatment medicine. The application comprises blocking of mutual combination between autophagy skeleton protein Beclin1 and an autophagy inhibiting factor Bcl-2 so as to induce nerve cell autophagy, and preparation of a Parkinson's disease treatment medicine. The triterpene compound is any one or a mixture of two of maslinic acid and tormentic acid. The Parkinson's disease treatment medicine provided by the invention comprises a pharmaceutically acceptable auxiliary material as well as an effective dosage of any one or a mixture of two of the maslinic acid and the tormentic acid. The triterpene compounds, namely the maslinic acid and the tormentic acid, are capable of directly blocking mutual combination between the autophagy skeleton protein Beclin1 and the autophagy inhibiting factor Bcl-2, so that the triterpene compounds have the function of promoting autophagy in nerve cells, and have a nerve protection function on Parkinson's disease cells. Therefore, the maslinic acid and the tormentic acid can be directly adopted to prepare the Parkinson's disease treatment medicine, and the Parkinson's disease treatment medicine is endowed with good medicinal effect.
Owner:THE HONG KONG POLYTECHNIC UNIV SHENZHEN RES INST +1
Application of tormentic acid and anisodamine capsule in preparation of medicine for treating diabetes
ActiveCN114053282AGood hypoglycemic effectAvoid reducing dissolution rateMetabolism disorderPharmaceutical non-active ingredientsDrug capsuleTormentic acid
Owner:江西金思康药业有限公司
Medicine composition for treating rheumatoid arthritis and preparation method thereof
The invention discloses a medicine composition for treating rheumatoid arthritis and a preparation method thereof. The medicine composition is prepared from the raw material medicines of herb of trifid sopubia, pogonatum aloides, beta-ionone, calanthe puberula and tormentic acid in proportion. Various dosage forms can be prepared according to a conventional preparation process, and the effect of treating rheumatoid arthritis is significant.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Medicine compositionc for preventing and treating hysteromyoma
InactiveCN106619771AOrganic active ingredientsPteridophyta/filicophyta medical ingredientsThyrocarpus sampsoniiTormentic acid
The invention discloses a medicine compositionc for preventing and treating hysteromyoma and a preparation method thereof. The medicine compositionc disclosed by the invention is prepared from the following crude drugs at a certain ratio: loxogramme chinensis, pogonatum aloides, thyrocarpus sampsonii, eupatilin, acrifoline and tormentic acid. The medicine compositionc can be prepared into various preparations according to a conventional preparation process and is effective in preventing and treating hysteromyoma.
Owner:JINAN HAOYU QINGTIAN PHARMA TECH CO LTD
Preparing method of loquat leaf total triterpenic acid and antidiabetic use thereof
The invention relates to a preparation method for triterpene acid of loquat leaf and the function of lowering the blood glucose. The preparation method comprises that dry loquat leaves are firstly extracted by ethanol or methanol with certain concentration, reclaimed in ethanol with low condensation for sedimentation, and centrifuged, precipitated and refluxing-decolorized with diatomite or done with chromatography with siliceous earth column, and then eluted with ethanol and reclaimed in condition of decompression and dried to obtain the triterpene acid of loquat leaf. Total content of ursolic acid, oleanolic acid, maslinic acid, corosolic acid and tormentic acid in the triterpene acid reaches more than 50 percent (by weight), wherein, the content of the tormentic acid is to be 10-30 percent, the maslinic acid 4-20 percent, the corosolic acid 5-20 percent, the oleanolic acid 1-10 percent and the ursolic acid 5-20 percent. The triterpene acid of loquat leaf prepared by the invention can be used for curing diabetes mellitus or preparing pharmaceutic preparations used for treating diabetes mellitus and diabetic complication.
Owner:INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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