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2007 results about "Disease treatment" patented technology

Medical professionals use medicine, therapy, surgery, and other treatments to help lessen the symptoms and effects of a disease. Sometimes these treatments are cures — in other words, they get rid of the disease. For example, doctors treat athlete's foot using antifungal creams, powders, or sprays that kill the fungus causing the disease.

Electronic medical record system and method

A system for storing medical records (15) which is comprised of a global communications network (12), a personal computer or terminal (14) linked to the global communications network (12) including a first connection port and a portable data access device connected to the first connection port is disclosed. The portable storage device preferably contains a processor, a memory, and an input device. An electronic patient record (15) is also disclosed. The patient record is carried by the portable data access device and may be updateable via the global communications network (12), the personal computer (14), or the input device acting in communication with the storage device. The patient record (15) contains personal patient information, such as disease / treatment history, and health insurance / medication information. The storage device may also generate patient reminders instructing a patient to schedule appointments. The input device is used to log into the portable device or terminal (14).
Owner:SIRKPATH

Pelvic disorder treatment device

A device for treating a medical condition is provided, and a surgical procedure for implanting the device is disclosed. The device includes a sensor, which is adapted to generate a signal responsive to a state of a patient, and at least one electrode, which is adapted to be coupled to a pelvic site of the patient. A control unit is adapted to receive the signal, to analyze the signal so as to distinguish between an imminent stress incontinence event and an imminent urge event, and, responsive to analyzing the signal, to apply an electrical waveform to the at least one electrode. In various configurations, the device may be used alternatively or additionally to treat fecal incontinence, interstitial cystitis, chronic pelvic pain, or urine retention.
Owner:ASTORA WOMENS HEALTH

Cardiac disease treatment and device

A device for treating cardiac disease of a heart having an upper portion and a lower portion divided by an A–V groove, the device including a jacket adapted to be secured to the heart, and a delivery source for the delivery of one or more therapeutic agents to the surface of the heart. The jacket is fabricated from a flexible material defining a volume between an upper and a lower end, the jacket being adapted to be adjusted on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain expansion of the heart beyond the maximum adjusted volume during diastole and permit substantially unimpeded contraction of the heart during systole. As a result of the flexible material, the jacket allows unimpeded diastolic filling of the heart. Also described is a method for treating cardiac disease including surgically accessing the heart, applying the treatment device of the invention, securing the treatment device to the heart, and surgically closing access to the heart while leaving the treatment device on the heart.
Owner:MARDIL

Methods for drug discovery, disease treatment, and diagnosis using metabolomics

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Owner:CORNELL RES FOUNDATION INC +1

Antiparkinson dosage form

A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
Owner:ENCINAL PHARMA INVESTMENTS

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

The invention provides a method for generating an oligonucleotide with which an exon may be skipped in a pre-mRNA and thus excluded from a produced mRNA thereof. Further provided are methods for altering the secondary structure of an mRNA to interfere with splicing processes and uses of the oligonucleotides and methods in the treatment of disease. Further provided are pharmaceutical compositions and methods and means for inducing skipping of several exons in a pre-mRNA.
Owner:ACADEMISCH ZIEKENHUIS BIJ DE UNIV VAN AMSTERDAM ACADEMISCH MEDISCH CENT

Treatment of B-cell associated diseases

Treatment of B-cell associated diseases including autoimmune and B-cell malignancies such as leukemias, lymphomas, using the combination of an anti-CD20 antibody, preferably RITUXAN® and a radiolabeled anti-CD22 antibody, preferably an 90Y labeled humanized anti-CD22 antibody, is described. These therapeutic regimens provide for enhanced depletion of B cells, and therefore reduce the risk in B cell malignancy treatment of relapse associated with RITUXAN® and, moreover, provide for prolonged immunosuppression of B-cell immune responses, especially in the context of autoimmune diseases and transplant.
Owner:BIOGEN INC

Modulation of exon recognition in pre-mRNA by interfering with the secondary RNA structure

The invention provides a method for generating an oligonucleotide with which an exon may be skipped in a pre-mRNA and thus excluded from a produced mRNA thereof. Further provided are methods for altering the secondary structure of an mRNA to interfere with splicing processes and uses of the oligonucleotides and methods in the treatment of disease. Further provided are pharmaceutical compositions and methods and means for inducing skipping of several exons in a pre-mRNA.
Owner:ACADEMISCH ZIEKENHUIS BIJ DE UNIV VAN AMSTERDAM ACADEMISCH MEDISCH CENT

Compact, handheld device for home-based acne treatment

InactiveUS20080091179A1Minimizes trauma and scar formationReduce the possibilityElectrotherapySurgical instrument detailsDiseaseMedicine
A compact, handheld device can be used to treat a sebaceous follicle disorder in a preselected dermal region of mammalian skin. A treatment can ameliorate at least one symptom of a lesion characteristic of the disorder.
Owner:CANDELA CORP

Disease treatment via antimicrobial peptides or their inhibitors

The invention provides methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. The invention also provides specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
Owner:HILLMAN YITZCHAK

Alzheimer's disease treatment with multiple therapeutic agents delivered to the olfactory region through a special delivery catheter and iontophoresis

This invention describes the administration of multiple therapeutic agents with insulin in conjunction with bexarotene, ketamine, monoclonal antibodies Etanercept, IGF-1, and acetylcholine esterase inhibitors physostigmine, for treatment of Alzheimer's disease and other neurodegenerative diseases. Insulin, improves memory; also augments and amplifies the effects of the adjuvant therapeutic agents (paracrine and intracrine effects) and consequently reduces the β amyloid, its soluble precursors, prevents damage to the neuronal skeletal network (taupathy), and blocks glutamate excitotoxicity, reduces brain inflammation, prevents apoptosis, and increases the acetylcholine levels in the neurons and synapses; by using a combination of insulin, bexarotene, ketamine, Etanercept, IGF-1, and physostigmine therapeutic agents. The results are achieved by using the specially designed Iontophoresis incorporated olfactory mucosal delivery (ORE) catheter device located at the olfactory nerves, sphenoid sinus, and adjacent structures described here, to transport the large molecules of therapeutic agents to treat AD delivered to the CNS bypassing BBB from ORE.
Owner:WEDGE THERAPEUTICS

SERS biological probe and method for making same

InactiveCN101216429AStrong SERS effectSignificant SERS effectRaman scatteringBiological testingProtein moleculesSignalling molecules
The invention discloses a SERS biological probe and a preparation method thereof. The SERS biological probe provided by the invention comprises a SiO2 core and a metal nanoparticle layer on the surface of the SiO2 core, wherein a plurality of Raman signal molecules connected with the metal nanoparticle layer; a SiO2 layer is also provided outside the metal nanoparticle layer; the Raman signal molecules are positioned between the metal nanoparticle layer and the SiO2 layer; the SiO2 layer surface is modified with biological probe molecules; and the metal nanoparticle layer is Au nanoparticle layer or Ag nanoparticle layer. The SERS biological probe provided by the invention has wide generality, and has wide application prospect in identification and detection of biological molecules (DNA molecules and protein molecules), rapid disease diagnosis, biomedical imaging technology as well as in the fields of serious disease treatment, food hygiene, environmental monitoring, etc.
Owner:CAPITAL NORMAL UNIVERSITY

Methods for drug discovery, disease treatment, and diagnosis using metabolomics

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Owner:METABOLON +1

Lipoic acid derivatives and their use in treatment of disease

This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
Owner:THE RES FOUND OF STATE UNIV OF NEW YORK

Cardiac disease treatment and device

A device for treating cardiac disease of a heart having an upper portion and a lower portion divided by an A-V groove, the device including a jacket adapted to be secured to the heart, and a non-adherent material in association with the jacket. The jacket is fabricated from a flexible material defining a volume between an upper and a lower end, the jacket being adapted to be adjusted on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain expansion of the heart beyond the maximum adjusted volume during diastole and permit substantially unimpeded contraction of the heart during systole. As a result of the flexible material, the jacket allows unimpeded diastolic filling of the heart. Also described is a method for treating cardiac disease including surgically accessing the heart, applying the treatment device of the invention, securing the treatment device to the heart, and surgically closing access to the heart while leaving the treatment device on the heart.
Owner:MARDIL

Methods for drug discovery, disease treatment, and diagnosis using metabolomics

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Owner:CORNELL RES FOUNDATION INC +1

Pelvic disorder treatment device

A device (20) for treating a medical condition is provided, and a surgical procedure for implanting the device is disclosed. The device (20) includes a sensor (44), which is adapted to generate a signal responsive to a state of a patient, and at least one electrode (27), which is adapted to be coupled to a pelvic site of the patient. A control unit (22) is adapted to receive the signal, to analyze the signal so as to distinguish between an imminent stress incontinence event and an imminent urge event, and, responsive to analyzing the signal, to apply an electrical waveform to the at least one electrode (27). In various configurations, the device (20) may be used alternatively or additionally to treat fecal incontinence, interstitial cystitis, chronic pelvic pain, or urine retention.
Owner:MEDTRONIC INC +1

Magnetic pole matrices useful for tissue engineering and treatment of disease

A magnetic pole matrix chip facilitating the grinding of magnetic particles carrying matter effective for treating a disease or promoting tissue engineering to a disease site or a tissue engineering site, respectively
Owner:STEINBEIS TRANSFERZENT FUR HERZ KREISLAUFFORSCHUNG

Ocular disorder treatment implants with multiple opening

Intraocular stents and applicators are disclosed for treating glaucoma. The stents are configured to extend between the anterior chamber of the eye and Schlemm's canal for enhancing outflow of aqueous from the anterior chamber so as to reduce intraocular pressure. The stents can have features for anchoring the stent into Schlemm's canal as well as preventing the walls of Schlemm's canal from closing the outlet of the stents. The applicators can be steerable so as to make implantation easier. Additionally, the applicators can be configured to hold a plurality of stents so that multiple stents can be implanted through one incision without removing the applicator from the incision between serial implantations.
Owner:GLAUKOS CORP

Methods for drug discovery, disease treatment, and diagnosis using metabolomics

The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Owner:CORNELL RES FOUNDATION INC +1

Ureido substituted benzoic acid compounds and their use for nonsense suppression and the treatment of disease

ActiveUS7405233B2Decreased amount of producedPromote readthrough of stop codonsAntibacterial agentsBiocideBenzoic acidDisease
The invention encompasses ureido substituted benzoic acid compounds, compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.
Owner:PTC THERAPEUTICS INC

Splice switch oligomers for TNF superfamily receptors and their use in treatment of disease

Methods and compositions are disclosed for controlling expression of TNF receptors (TNFR1 and TNFR2) and of other receptors in the TNFR superfamily using compounds that modulate splicing of pre-mRNA encoding these receptors. More specifically these compounds cause the removal of the transmembrane domains of these receptors and produce soluble forms of the receptor which act as an antagonist to reduce TNF-α activity or activity of the relevant ligand. Reducing TNF-α activity provides a method of treating or ameliorating inflammatory diseases or conditions associated with TNF-α activity. Similarly, diseases associated with other ligands can be treated in like manner. In particular, the compounds of the invention are splice-splice switching oligomers (SSOs) which are small molecules that are stable in vivo, hybridize to the RNA in a sequence specific manner and, in conjunction with their target, are not degraded by RNAse H.
Owner:SANTARIS PHARMA AS +3

Nutritional conjunctive support therapy for recovery in animals following stress or illness

A composition of probiotics, vitamins and minerals, electrolytes with glutamine and glucose along with medium chain triglycerides are provided as a supplement to animals. This is administered to cattle, calves, sheep, pigs, horses, dogs, and cats that are experiencing stress and or are undergoing medical drug therapy to treat conditions of diseases along with pre and post operative surgical conditions. The composition helps correct imbalances in beneficial bacteria, provides energy and helps in rehydration to reduce recovery time from stress or in disease treatment in these animals.
Owner:VETAB PLUS

Soluble TNF receptors and their use in treatment of disease

The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular, the proteins are mammalian TNFRs that lack exon 7 and which can bind TNF and can act as a TNF antagonist.
Owner:NORTH CAROLINA AT CHAPEL HILL THE UNIV OF +2
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