The invention discloses a synthesis method for dopa-containing oligopeptide and application of the dopa-containing oligopeptide in antiparkinsonian prodrugs. According to the synthesis route, in the synthesis process, a prepared dopa-containing dipeptide intermediate protected by actonide has good stability and can be stably stored for a long time, and the dopa-containing dipeptide can be converted only in one step, which overcomes the defects that the dopa-containing dipeptide structure is not stable and cannot be stored for a long time. The method has the advantages that the universality isgood, the defect that a reflux reaction is needed in the prior art is overcome, the reaction condition is mild, side reactions are fewer, the cost of raw materials is lower, and the product has higherpurity and is easy to separate; the prepared dopa-containing dipeptide has good stability in liver homogenate and strong degradation resistance, is expected to be developed into a high-bioavailability and long-acting Parkinson's disease treatment drug, and is expected to significantly reduce the side effects of L-DOPA in treating the Parkinson's disease due to the fact that the bioavailability isgreatly improved.