5 results about "Amantadine" patented technology

The utility model discloses an amantadine amination process reaction device, which belongs to the technical field of reaction equipment, and comprises a reaction kettle for amantadine amination reaction, the top end of a base is fixedly connected with a mounting frame, and the inner side of the mounting frame is rotatably connected with two driving shafts connected with the reaction kettle; the side surface of the mounting frame is provided with a fixed end of a stepping motor, the driving end of the stepping motor and the periphery of the driving shaft are both provided with gears, the two gears are in meshed connection, the side surface of the reaction kettle is provided with a heating assembly, and the side surface of the mounting frame is provided with a fixed end of a second hydraulic rod; and the driving end of the second hydraulic rod penetrates through the mounting frame and is fixedly connected with a limiting plate, the side face of the limiting plate is provided with the fixed end of a servo motor, and the driving end of the servo motor is fixedly connected with an L-shaped linkage plate. According to the amantadine amination process reaction device, the reaction kettle can be automatically cleaned, so that the cleaning operation of the device is more time-saving and labor-saving.

New use of 1-amino-3,5-dimethyladamantane hydrochloride in treating or preventing cognitive impairment, reducing microglia in the cortex and hippocampus, reducing neuron loss in the cortex and hippocampus, and ameliorating the mitochondrial dysfunction state. The cognitive impairment includes cognitive impairment in systemic lupus erythematosus, Parkinson's disease, lateral sclerosis, stroke, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, attention deficit hyperactivity disorder, sepsis-related encephalopathy, or mild cognitive disorder. The present application also provides a corresponding drug and a treatment or prevention method.

Opiperidone for use as an adjuvant therapy of levodopa and a DOPA decarboxylase inhibitor (DDCI) formulation in the treatment of Parkinson's disease; the method is characterized in that a patient suffering from Parkinson's disease can be treated with levodopa and DDCI preparations without clinically diagnosed motor complications.

The invention relates to the field of food detection, in particular to an analysis and detection method for antiviral drug residues in eggs, which comprises the following steps: S1, sample pretreatment: 1.1, sample preparation: shelling eggs, homogenizing, and storing at 4 DEG C; 1.2, extracting: weighing a homogenate sample, extracting twice by using 90% acetonitrile-1% formic acid solution, and merging supernate; 1.3, purifying and redissolving: purifying the supernate through an EMR-Lipid solid-phase extraction column, collecting eluent, blowing the eluent to be nearly dry at 40 DEG C by nitrogen, redissolving by using a formic acid-methanol solution, and filtering to obtain a matrix extracting solution; s2, preparing a standard solution; s3, instrument detection: performing chromatography-tandem mass spectrometry detection; s4, quantitative analysis: calculating the residual quantity of the eight antiviral drugs in the eggs according to the quantitative ion peak area by adopting a matrix matching standard curve external standard method. The precise detection of eight viruses, namely nevirapine, peramivir, famciclovir, rimantadine, amantadine, oseltamivir, imiquimod and memantine, is realized.