4 results about "Neurodermatitis" patented technology

This invention discloses a long-acting antipruritic and antibacterial topical skin preparation, comprising N-ethyl-γ-L-glutamine, 1-1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphate-N-(L-γ-glutamyl-N-ethyl)-ethanolamine (POPE-N-Et-Gln-α), chlorhexidine acetate, and saffron extract as active ingredients, formulated into a hydrogel or cream with a pharmaceutically acceptable matrix. POPE-N-Et-Gln-α provides rapid transdermal action, while N-ethyl-γ-L-glutamine offers sustained-release and long-lasting effects; saffron extract provides anti-inflammatory and antioxidant effects, and chlorhexidine acetate provides antibacterial and antifungal effects. This invention is hormone-free and non-addictive, achieving both rapid and long-lasting antipruritic effects, and is suitable for eczema, urticaria, dry skin, neurodermatitis, psoriasis, microbial infections, and skin itching caused by insect bites.

The invention belongs to the field of skin disease treatment, and provides a patch for treating neurodermatitis and a preparation method and application of the patch. The medicinal components comprise a lithospermum extract, a menthol compound and wintergreen oil; the adhesive matrix comprises a framework material, a tackifier, a softener and a cohesive high polymer material; the mass of the framework material accounts for 8-55% of the total mass of the adhesive matrix; the mass of the tackifier is not higher than 60% of the total mass of the adhesive matrix; the mass of the softening agent is not higher than 65% of the total mass of the adhesive matrix; the cohesive high polymer material accounts for not more than 10% of the total mass of the adhesive matrix; the mass of the lithospermum extract is not higher than 60% of the total mass of the medicinal components; the mass of the menthol compound accounts for not more than 75% of the total mass of the medicinal components; the wintergreen oil accounts for not higher than 65% of the total mass of the medicinal components. The patch has a remarkable treatment effect on neurodermatitis diseases.

The invention discloses a traditional Chinese medicine composition for treating skin inflammation as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 5 to 30 parts of snake slough, 5 to 30 parts of cortex dictamni, 10 to 50 parts of fructus mume, 5 to 30 parts of cortex fraxini, 5 to 30 parts of radix arnebiae seu lithospermi, 10 to 40 parts of radix isatidis, 10 to 40 parts of rhizoma anemarrhenae, 10 to 40 parts of gypsum and 5 to 30 parts of folium isatidis. The traditional Chinese medicine composition can effectively inhibit pruritus and inflammatory response caused by various dermatitis including neurodermatitis, accelerate tissue repair and healing processes of burn and scald parts, promote fading of red and swollen parts caused by mosquito bites, relieve local edema and discomfort and promote body function recovery.

A kind of nitrogen-containing heterocyclic protein inhibitor compound, its stereoisomer, tautomer or pharmaceutically acceptable salt, also provides preparation of nitrogen-containing heterocyclic compound and its use, the drug prepared using the compound is widely used in the treatment of diseases, wherein the diseases include multiple types of autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, lupus erythematosus, neurodermatitis, dermatitis, psoriasis, psoriatic arthritis, Crohn's disease, Sjogren's syndrome and scleroderma.