36 results about "Chronic alcoholism" patented technology

The invention provides a functional product composition for sobering up and protecting the liver, comprising effective components and auxiliary materials which are acceptable in the medicine. The functional product composition for sobering up and protecting the liver is characterized in that the effective components are prepared by the following raw material medicines according to parts by weight: 5-60 parts of soybean protein, 4-50 parts of zein, 3-40 parts of ginseng, 2-40 parts of radix puerariae and 2-40 parts of raisin tree fruit. The composition can quickly lower the concentration of ethanol in blood after drinking, quickens the sobriety recovery of the brain and has very good functions of sobering up and restoring consciousness; the composition also can effectively treat acute alcoholism, prevents chronic alcoholism and lowers the injury of alcohol to liver cells.

Chronic alcoholism is a diverse and heterogeneous disorder that can be dichotomized into cognitively intact and cognitively impaired subgroups. At a molecular level, ethanol has been shown to have both acute and chronic effects on: Membrane biophysical properties, Membrane composition and metabolism, Protein phosphorylation, Lipid metabolic signaling, Lipoprotein transport of cholesterol. Actual molecular underpinnings are determined for cognitive impairment seen in some chronic alcoholism subjects including molecular/metabolic alterations of phospholipid and ganglioside metabolisms.

The invention relates to a medicinal composition for sobering and a relevant preparation process. The preparation process comprises the following steps of: performing microwave extraction on kudzuvine root, flos puerariae, chrysanthemum, linearstripe rabdosia herb, gardenia root, semen hoveniae and fructus amomi which serve as raw material from Chinese medicinal herbs which are homologous in medicines and food, filtering, performing the microwave extracting again, evaporating, concentrating and drying to obtain a sample. The medicinal composition has a certain sobering function, and can resist acute alcoholic liver injury, chronic alcoholism and lipid peroxidation of livers, kidneys and brains of mice, reduce the level of triglyceride, prevent the formation of fatty liver and protect livers.

A levo-potassium magnesium aspartate freeze-dried powder injection consists of levo-potassium aspartate, levo-magnesium aspartate, freeze-dried power supporting agent and pH regulator. it is a kind of electrolyte extender, contains no crystal water, and has pH value of 5-11.5, large dosage, physical stability not affected by temperature and no pollution. It has wide application range, and is suitable for intravenously guttae to treat arrhythmia caused by various causes, chronic alcoholism fremitus, myocardiopathy as diabetes complication, etc. and application in heart operation. It is also suitable for acute and chronic hepatitis, intrahepatic cholestasis, and diseases of respiratory system, nerve system and metabolic system.

A leveo-potassium magnesium aspartate infusion injection consists of levo-potassium aspartate, levo-magnesium asparatate, osmotic pressure regulator and pH regulator. It is a kind of electrolyte extender for infusion, and has pH value of 5-11.5, high concentration, large dosage, high stability and no pollution. it has wide application range, and is suitable for intravenously guttae to treat arrhythmia caused by various causes, chronic alcoholism fremitus, myocardiopathy as diabetes complication, etc. and applicaltion in heart operation. It is also suitable for acute and chronic hepatitis, intrahepatic cholestasis, and disease of respiratory system, nerve system and metabolic system.

This invention relates to a method for preparing metadoxine. The method comprises: adding isopropanol to mixed solid powder of vitamin B6 alkali and pyroglutamic acid, reacting at 25-45 deg.C for 30 min-24 h, filtering, and drying the solid to obtain metadoxine. The mol. ratio of vitamin B6 alkali to pyroglutamic acid is 1:1. The weight ratio of pyroglutamic acid to isopropanol is 1 :( 1.0-4). The content of deionized water in isopropanol is 0-5%. The method has such advantages as no need for refinery, low solvent consumption, low cost, simple process, easy operation and high yield, and is suitable for industrialization. The obtained drug-grade metadoxine can be used to treat acute and chronic alcoholism and alcoholic liver disease.

The invention discloses a traditional Chinese medicine composition for treating a chronic alcoholic liver disease and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the raw materials of white paeony root, rhizoma corydalis, hawthorn, rourstamen stephania root, tangerine peel, capillary artemisia, ligusticum wallichii, curcuma zedoaria, angelica sinensis, honeysuckle stem, flos sophorae, lotus aeedpod, tribulus terrestris, ligustrum lucidum, bupleurum, poria cocos, scutellaria baicalensis, cassia twig, jujube and glycyrrhiza. The traditional Chinese medicine composition has a very good therapeutic effect in the aspect of treating the chronic alcoholic liver disease and has remarkable clinic popularization value.

A medicine in the form of oral liquid, instant particles, tablet, or capsule for treating acute or chronic alcoholic liver damage contains bitter pattra fruit, pueraria flower, VB6, ginsenoside, active substance and one or more medicinal carrier. It is prepared through crushing bitter pattra fruit and pueraria flower, mixing, immersing in water, heating for 30-60 min, filtering, decocting the dregs, filtering, collecting filtrate, concentrating, vacuum drying, and mixing with VB6 and ginsenoside.

The invention belongs to the technical field of medicine, relates to a traditional Chinese medicine composition, and in particular relates to a traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease and a preparation method thereof. Aiming at the current technical defects of lack of comprehensive and effective treatment on the chronic alcoholic toxic liver disease, easiness in relapse of chemical treatment, and inconstant curative effect, the invention provides the traditional Chinese medicine composition for treating chronic alcoholic toxic liver disease. The traditional Chinese medicine composition comprises the following components: 10 parts of rhizoma alismatis, 15 parts of Fourstamen Stephania root, 6 parts of herba artemisiae, 10 parts of fleece-flower root, 10 parts of rhizoma ligustici wallichii, 6 parts of angelica, 20 parts of hovenia dulcis, 20 parts of Chinese gall, 10 parts of radix bupleuri, 12 parts of rhizoma polygonati, 15 parts of Scutellaria baicalensis, 30 parts of Lycium barbarum L., 6 parts of Poria cocos, and 10 parts of liquorice. The traditional Chinese medicine composition has a very good treatment effect in the treatment of chronic alcoholic toxic liver disease, and has significant clinical promotion value.

The invention relates to application of raja porosa extract in alcoholic brain damage protection medicine. The raja porosa extract is extracted from raja porosa cartilage and can improve the activity of SOD and GSH-PX in the brain tissue of rats with chronic alcoholism, reduce MDA and beta-EP in the brain tissue, the protection effect on the brain damage of the rats with chronic alcoholism is achieved, the raja porosa extract can be prepared into various dosage forms and can serve as an alcoholic brain damage protecting agent, and the raja porosa extract has the advantages of being remarkable in curative effect, free of side effects, low in price, safe and convenient to use.

The present invention provides the uses of 5-methyltetrahydrofolate and its composition. The 5-methyltetrahydrofolate or its composition is used to treat, relieve or prevent diseases or symptoms caused by acute alcohol intoxication and chronic alcohol intoxication. The injuries or diseases caused by the acute alcohol intoxication include: headaches caused by drinking, negative emotions or depression caused by drinking, and hangover symptoms after drinking. The injuries or diseases caused by the chronic alcohol intoxication include: alcoholic fatty liver, central nervous system (CNS) inflammation, etc.

The invention discloses a composition for dispelling effects of alcohol and protecting liver. The composition is prepared from the following raw materials in parts by weight: 3 to 8 parts of white tea, 5 to 15 parts of radix puerariae, 5 to 15 parts of flos puerariae, 4 to 10 parts of semen hoveniae, 2 to 4 parts of olive, 3 to 6 parts of fructus lycii, 5 to 10 parts of fructus crataegi, 10 to 15 parts of fructus amomi, 5 to 15 parts of fructus amomi rotundus, 2 to 4 parts of radix aucklandiae, 3 to 5 parts of radix ginseng, 4 to 8 parts of rhizoma atractylodis macrocephalae, 2 to 4 parts of flos sophorae, 2 to 4 parts of vine tea, 4 to 8 parts of lotus leaves, 2 to 8 parts of orange peel, 4 to 8 parts of medicated leaven and 4 to 8 parts of rhizoma zingiberis. The composition disclosed by the invention has the effects of improving the detoxification effect of the liver, accelerating the decomposition and excretion of ethanol in a body and improving the oxidation resistance of the liver so as to relieve alcohol damage, and has a remarkable effect of preventing and treating acute and chronic alcoholism and relieving hangover.