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8 results about "Normal control" patented technology

Normal and Abnormal Controls. A normal control product contains normal levels for the analyte. An abnormal control product contains the analyte at a concentration above or below the normal range for the analyte. For example, the normal range for a potassium level is approximately 3.5–5.0 mmol/L.

Application of hydrogen-rich water in preparation of drug for treating Duchenne type muscular dystrophy

The invention discloses application of hydrogen-rich water in preparation of a drug for treating Duchenne type muscular dystrophy, and particularly relates to the technical field of medicines.The random control experiment is adopted, homologous c57 mice serve as a normal control group, mdx mice are randomly divided into a model group and a hydrogen-rich water group, and the exercise ability is evaluated through a four-limb holding power test and a rotating bar test; detecting mouse creatine kinase by an enzyme-linked immunosorbent assay; carrying out hematoxylin-eosin, NADH-tetrazole reductase and improved Goori three-color dyeing, and carrying out cytochrome C oxidase, succinate dehydrogenase and SDH-COX combined dyeing to observe the pathological change of the skeletal muscle tissue; the invention discloses that the muscle injury condition of a Duchenne type muscular dystrophy model mouse is improved by the hydrogen-rich water through a mitochondrial protection mechanism, and the hydrogen-rich water has a relatively high application prospect and a relatively high economic value.
Owner:ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Tissue based RNA in situ hybridization for diagnosis and treatment selection in dermatology

In various aspects and embodiments the invention provides a method of treating an autoimmune or autoinflammatory dermatological condition in a subject in need thereof, the method comprising: performing RNA in situ hybridization on a tissue sample obtained from the patient with at least one probe that binds to a polyribonucleotide encoding at least one cytokine to determine a level of the at least one cytokine; comparing the level of the at least one cytokine to a normal control; determining that the level of the at least one cytokine deviates from the normal control; and providing treatment for the dermatological condition to the subject.
Owner:YALE UNIVERSITY

A method for establishing a model of cancer-related fatigue in zebrafish

The application relates to the field of drug evaluation, and discloses a method for establishing a zebrafish cancer-related fatigue model to solve the problems of the existing technology, such as difficulty in controlling the dosage of a chemotherapeutic drug, more cumulative toxicity of experimental animals, easy death, long modeling time, small flux and difficult operation, and the method comprises the following steps: selecting normal development zebrafish 4 days after fertilization, placing the zebrafish in a microwell plate, dividing the zebrafish into a normal control group and a model group, injecting the zebrafish in the model group with vinorelbine tartrate injection through intravenous injection, and not treating the normal control group; culturing the normal control group and the model group in a zebrafish culture solution at a constant temperature; comparing the total movement distance of the zebrafish in the control group and the model group; if the total movement distance of the zebrafish in the model group is significantly less than that of the normal control group, then the zebrafish cancer-related fatigue model is successfully established. The model is short in time required for establishment, simple in operation, and can realize efficient and high-flux evaluation of the anticancer-related fatigue effect of a drug.
Owner:HANGZHOU HUANTE BIOLOGICAL TECH CO LTD

Ventilation regulation system

ActiveCN117547696BTidal volumeControl signal
This invention relates to a ventilation control system, comprising a control unit capable of generating control signals for adjusting the operating parameters of a ventilator. The control unit is capable of determining a normal control scheme in the following manner: determining several influencing parameters; inputting the determined influencing parameters into an established lung model to calculate the respiratory rate; calculating the inspiratory and expiratory times using the respiratory rate; calculating the tidal volume using the respiratory rate and determining the corresponding normal control scheme according to the calculated tidal volume, wherein the initially determined normal control scheme is used as the initiation scheme; and iteratively optimizing the respiratory rate to calculate the inspiratory time, expiratory time, and tidal volume of the next sequence, thereby updating the normal control scheme.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Application of small molecule compound in preparation of medicine for treating left ventricular insufficiency

The invention discloses an application of a small molecule compound in preparation of a medicine for treating left ventricular densification insufficiency, the small molecule compound is N-(4-chlorphenyl)-5-methyl-N-(4-methyl-4, 5-thiazolidine-2-yl)-3-phenylisoxazole-4-formamide, and the CAS number of the small molecule compound is 878090-53-0. A left ventricular non-compact layer of a newborn mouse intervened by the small molecule compound is obviously thinned, a compact layer is obviously thickened, and the N / C ratio of the nipple muscle level and the cardiac apex segment is from gt of the model group; 2.5 is obviously reduced to 1t; 0.8, the small molecule compound basically recovers to a normal control level, that is, the small molecule compound has a relatively good prevention and / or treatment effect on left ventricular insufficiency.
Owner:SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL

A multi-contact system and a control method of an electronic expansion valve for heating

The application discloses a multi-connected system and a control method of an electronic injection enthalpy expansion valve during heating of the multi-connected system. The multi-connected system is started and enters a soft start stage. In the soft start stage, the electronic injection enthalpy expansion valve is closed, and after the multi-connected system runs for a time length A, the multi-connected system enters a normal control stage. In the normal control stage, when the frequency of the compressor reaches B, the multi-connected system determines whether the electronic injection enthalpy expansion valve is opened according to the ambient temperature and the indoor unit load rate, and the initial opening degree of the electronic injection enthalpy expansion valve after being opened. If the electronic injection enthalpy expansion valve is opened and maintained for a time length C, the multi-connected system determines a target high-pressure saturated temperature according to the current ambient temperature, and then adjusts the opening degree of the electronic injection enthalpy expansion valve according to the difference between the target high-pressure saturated temperature and the actual high-pressure saturated temperature. In this way, the electronic injection enthalpy expansion valve can be adjusted from multiple aspects, the state of the multi-connected system is detected in real time during the opening of the electronic injection enthalpy expansion valve, and the customer comfort and the system reliability are improved.
Owner:ZHEJIANG ZHONGGUANG ELECTRIC CO LTD

Refrigeration cycle device

PCT designated stageWO2026048861A1Compression machines with non-reversible cycleCondensation temperatureNormal control
The present invention ensures reliability of a compressor at the startup of an air conditioner, and improves startup capability. The present invention comprises: a refrigerant circuit (C) in which a compressor (1), a condenser (2), a decompression mechanism (3), and an evaporator (4) are sequentially connected by refrigerant piping, and through which a refrigerant circulates; a condenser fan (21) that sends air to the condenser (2); a condensation temperature detection sensor (22) that detects the condensation temperature of the refrigerant at startup; a condenser suction air temperature detection sensor (23) that detects the temperature of the air sucked into the condenser (2); and a control device (6) that switches between startup control and normal control. The control device (6) executes the startup control at startup, and terminates the startup control and switches to the normal control when a startup temperature difference obtained by subtracting the air temperature detected by the condenser suction air temperature detection sensor (23) from the condensation temperature detected by the condensation temperature detection sensor (22) is greater than a preset temperature difference threshold value.
Owner:FUJITSU GENERAL LTD