1085results about How to "Early detection" patented technology

Apparatus and methods for the treatment of atrial fibrillation are described herein where tissue to be ablated may be monitored under direct visualization. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to the tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid can be pumped into the imaging hood until the fluid displaces any blood leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. An ablation probe may be advanced into the contained region where the tissue may be ablated and monitored for changes in color as well as appropriate positioning.

Methods for the detection of inflammation associated with vulnerable atherosclerotic plaque to prevent heart attack and stroke are disclosed. The methods are also applicable to detection of infection, cancer, wounds or auto-immune disease in the body. Certain embodiments of the new methods provide a way of predicting the level of vulnerability of an atherosclerotic plaque to rupture or thrombus formation by assessing via fiber optic NIR spectrophotometry the status of two or more parameters associated with inflamed atherosclerotic plaque in a vessel of a living patient. From these measurements such conditions as low pH, hypoxia, low glucose, oxidative stress or compounds abundant in vulnerable plaque such as oxidized LDL cholesterol and oxidized metabolites of NO, significant active macrophage population, thin plaque cap, as well as senescence and/or apoptosis of smooth muscle or endothelial cells are determined with the assistance of a suitably programmed microprocessor. By considering together the status of some or all of these conditions with respect to successive sites along a vessel wall, particular plaques which are at significant risk of rupturing or thrombosing can be distinguished from “normal” vessel wall and from “intermediate” and relatively stable or “lower risk” plaques. Sites having more of the indicator conditions would be considered most in need of prompt intervention, and certain combinations of parameter levels would be suggestive of relatively stable plaque.

Also disclosed is a multi-parameter catheter and analytical processing assembly for use in the methods.

A blood glucose meter having a compact housing, a display unit disposed on the housing, the display unit including a display light source to illuminate the display unit,an input unit disposed on the housing, the input unit configured to provide input functions for the blood glucose meter, and a power source provided within the housing for providing power to the blood glucose meter, where the housing includes a port integrated on said housing configured to receive a blood glucose test strip, and corresponding methods of measuring blood glucose meter is provided.

A method and device for monitoring at least one vehicle passenger in a vehicle involves capturing images of the vehicle passenger using an image capturing unit and analyzing the captured images using an image processing unit. At least one vital sign of the vehicle passenger is determined by the image analysis of the captured images, which can be used to operate at least one assistance device of a vehicle.

Systems and methods for diagnosing and/or treating diseases as well as monitoring disease treatment. For diagnosis, the present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker; and a means for detecting a specific chemical entity. In certain embodiments, nanoparticle-based assemblies include a payload for simultaneous diagnosis and treatment of disease. In further embodiments, a therapeutic drug and therapeutic drug marker are administered to a patient to monitor disease treatment. Bodily fluid samples are analyzed using sensor technology to detect the presence of surrogate and/or therapeutic drug markers to provide an efficient and accurate means for diagnosing a disease and/or monitoring disease treatment.

Systems and methods for diagnosing and/or treating conditions, diseases, or disorders. The present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker; and a means for detecting a specific chemical entity. Such nanoparticle-based assemblies combine nanotechnology and sensor technology to provide an efficient and accurate means for diagnosing a condition, disease, or disorder as well as for focused treatment regimens.

A building monitoring computer system for monitoring building integrity may be provided. Various types of sensors may be embedded throughout or within certain portions of different types of building or construction material making up the building, such as within roofing, foundation, or structural materials. The sensors may be in wireless communication with a home controller. The sensors may be water, moisture, temperature, vibration, or other types of sensors, and may detect unexpected or abnormal conditions within the home. The sensors and/or home controller may transmit alerts to a mobile device of the home owner associated with the unexpected condition, and/or that remedial actions may be required to repair the home or mitigate further damage to the home. The sensor data may also be communicated to an insurance provider remote server to facilitate the insurance provider communicating insurance-related recommendations, updating insurance policies, or preparing insurance claims for review for home owners.

Systems and methods are provided for detecting performance degradation in a refrigeration system. Specifically, the present invention provides systems and methods for detecting, at a very early stage, a low refrigerant charge and degradation in condenser performance of a refrigeration system.

Improved data transport and management within a network communication system may be achieved by utilizing a transmit timer incorporated within the sender device and exploiting host-level statistics for a plurality of connections between a sender and receiver. The period of the transmit timer may be periodically adjusted based on a ratio of the smoothed round-trip time and the smoothed congestion window, thereby reducing or eliminating bursty data transmission commonly associated with conventional TCP architectures. For applications having a plurality of connections between a sender and a receiver that share a common channel, such as web applications, the congestion window and smoothed round trip time estimates for all active connections may be used to initialize new connections and allocate bandwidth among existing connections. This aspect of the present invention may reduce the destructive interference that may occur as different connections compete with one another to maximize the bandwidth of each connection without regard to other connections serving the same application. Error recovery may also be improved by incorporating a short timer and a long timer that are configured to reduce the size of the congestion window and the corresponding transmission rate in response to a second packet loss with a predefined time period in order to increase resilience to random packet loss.

The present invention relates to, in part, methods, reagents and apparatuses for the detection of agents. The present invention also relates, in part, to compositions including, but not limited to, flow cells, assay chambers, reagent reservoir delivery units and devices for holding an assay chamber. The present invention also provides various components and combinations of components for various detection apparatuses. The present invention also relates to a portable agent detection apparatus that can be used in the field or at a point of care and is not limited to specialized laboratories or limited to use by highly skilled users.

Methods for assessing the risk of developing Type 2 diabetes and other related disorders include obtaining an NMR derived reference spectrum for a known glucose concentration sample and storing this information as a reference standard. A patient blood sample is collected and NMR derived patient spectrums for the blood sample are obtained. The two NMR data sets (the reference and the patient) are compared and a glucose concentration is determined for the patient sample. The glucose concentration can be evaluated with a blood sample undergoing lipoprotein cholesterol evaluation. The NMR based test can be used to concurrently provide a glucose concentration and lipoprotein constituent values based on a single testing event. The disclosure also includes a multi-purpose test, i.e., a test which concurrently provides lipoprotein screening and coronary heart disease risk evaluation along with a diabetes screening and risk assessment for developing Type 2 diabetes. A method for assessing diabetes includes identifying the presence of diabetic dyslipidemia based on the values of predetermined NMR measured lipoprotein constituents.

Ambulatory or in-hospital monitoring of patients is provided with early warning and prioritization, enabling proactive intervention and amelioration of both costs and risks of health care. Multivariate physiological parameters are estimated by empirical model to remove normal variation. Residuals are tested using a multivariate probability density function to provide a multivariate health index for prioritizing medical effort.

Techniques for detecting coagulum formation on an ablation electrode make use of an ablation electrode that is connected to a radio-frequency (RF) generator capable of applying a small amount of RF energy that is not cell destructive. The temperature at the ablation electrode can be precisely measured using a thermosensor incorporated within the ablation electrode. Before and after actual ablation, a low, non-cell destructing (non-ablating) amount of RF energy is generated at the ablation electrode. If no coagulum has formed during actual ablation, the temperature increase during this test application will be similar before and after the ablation attempt. If coagulum has formed during the actual ablation, however, the temperature increase during the test application after ablation will be significantly higher.

Dynamic management of the health care, nutrition and well-being of pet animal, such as a dogs and cats. Data relating to the species of the animal, a selected group of the species, and the animal, including diagnostic laboratory test data of the animal are related by a computer. A management regimen for the animal is based on this. Updating the data picks up drifts in different populations of the animals, groups and species over time to enhance the management.

The invention relates to a method for determining the position of a catheter in a blood vessel relative to a change in the vascular cross section, comprising the steps: providing a catheter that includes at least two electrodes which can be brought into electrically conductive contact with the surrounding blood while the catheter is being positioned in the blood vessel, wherein the two electrodes are installed on the catheter along the longitudinal axis at a defined distance from each other; advancing the catheter in the vessel to be treated, toward the change in the vascular cross section; and measuring the impedance across the two electrodes while the catheter is being advanced; and to a catheter for use in a method of this type.

A fire in an enclosed space in an aircraft is, for example, visually detected early since smoke generated by a beginning fire is initially permitted to escape from the enclosed space. The enclosed space is, for example, an overhead luggage bin or a goods container holding food or freight. The smoke can pass through a flow passage either in the form of a gap or a leak between a lid and walls, or between a door and a door frame, or between walls and other walls joined together. Intumescent material is installed along the gaps or leaks and expands into the gaps or leaks when the fire has generated a temperature sufficient for causing the expansion of the intumescent material. Preferably a guide surface assures that the intumescent material expands into the gaps and leaks and cannot expand away from gaps and leaks.

Fault trees are automatically converted to Bayesian networks for assisting in system reliability, failure analysis and diagnostics by using information from the fault tree structure to create the Bayesian network structure, creating parameters of the Bayesian network using information from the fault tree, obtaining information about observation nodes for the Bayesian network from a list of observations that augments information contained in the fault tree, and inserting the observation nodes into the Bayesian network. The fault tree is pre-processed into an intermediate format prior to conversion that may include adding reliability values from a separate text document when the fault tree is in such format that requires it.

An apparatus and method for operating a non-volatile memory including an array of bit cells. A selection is made between an operational power supply and a test power supply, the test power supply being on-chip programmable. The non-volatile memory is operated in a operational mode if the operational power supply is selected, and in a test mode if the test power supply is selected.

An apparatus, system and method provide data indicative of cardio-respiratory state of a patient. Two or more cardio-respiratory parameters of the patient are measured, and optionally monitored over time, the two or more cardio-respiratory parameters being different one from the other and being measured at a same anatomical part of said patient.

The present application discloses a a baby health monitoring device comprising a skin temperature sensor connected to a microprocessor for mathematically converting the sensed temperature to corrected skin temperature; a movement sensor; a display screen for indicating condition of baby; and a means for communicating with a computer.

A network traffic analysis method for tracking, analyzing, and mitigating security threats in a network includes receiving information based on monitoring traffic at a plurality of layers at one or more monitors deployed in the network utilizing deep packet inspection; receiving information based on monitoring the traffic at an endpoint of the network; analyzing the monitored traffic from the endpoint and the one or more monitors to determine network infrastructure and cyber security posture of the network infrastructure; and providing visualizations based on the network infrastructure and the cyber security posture, continuously to track threats, watch lateral movement in the network of the traffic, and determine security event history in the network.

A portable terminal is activated when receiving verification power transmitted in a contactless manner from a charger using electromagnetic coupling between the charger and the portable terminal. The portable terminal sends an electrical signal (wakeup frame) indicating activation immediately after being activated to the charger. Reception of the wakeup frame triggers the power transmitting device to start a verification process on the power receiving device and perform a detection process for a metal foreign object. After authentication is established, the charger transmits normal power to the portable terminal.

A method of assessing the ongoing kidney status of a mammal afflicted with or at risk of developing chronic renal injury or disease, including chronic renal failure (CRF) by detecting the quantity of Neutrophil Gelatinase-Associated Lipocalin (NGAL) in urine, serum or plasma samples at discrete time periods, as well as over time. Incremental increases in NGAL levels in CRF patients over a prolonged period of time are diagnostic of worsening kidney disease. This increase in NGAL precedes and correlates with other indicators of worsening chronic renal disease or CRF, such as increased serum creatinine, increased urine protein secretion, and lower glomerular filtration rate (GFR). Proper detection of worsening (or improving, if treatment has been instituted) renal status over time, confirmed by pre- and post-treatment NGAL levels in the patient, can aid the clinical practitioner in designing and/or maintaining a proper treatment regimen to slow or stop the progression of CRF.