10 results about "Adenoma" patented technology

This invention discloses a high-performance computing-based system and method for evaluating colorectal cancer screening strategies, belonging to the field of medical information processing technology. It includes: a dual-pathway disease model module supporting both adenoma-carcinoma pathways and serrated adenoma pathways, modeled using age-dependent normal distribution progression time; an individualized risk scoring module integrating risk factors such as family history, inflammatory bowel disease, obesity, and diabetes; a screening strategy simulation module supporting combined screening strategies using different tools, employing compliance parameters specific to the Chinese urban population; a high-performance computing module using Numba JIT compilation technology for acceleration, multi-process parallel processing for further acceleration, and data structure optimization such as integer age to reduce memory usage; and a health economics evaluation module calculating indicators such as QALY, LYG, and ICER. This invention achieves significant performance improvements while maintaining model accuracy, greatly reducing simulation time for large-scale populations.

The application relates to a thymoma epithelial cell subpopulation with neuromuscular characteristics and application, and a thymoma epithelial cell subpopulation with neuromuscular characteristics is obtained through single clone dilution culture screening from a thymoma cell line Thy0517 of a patient with myasthenia gravis (MG) in combination, and a thymoma epithelial cell with neuromuscular characteristics in the cell subpopulation is named as Thymus_NMi; the cell subpopulation has synapse-like structures and neuromuscular adhesion characteristics, and efficiently expresses genes participating in neural cell adhesion and synapse connection, highly integrates neuromuscular double characteristics, and simulates key pathological characteristics of abnormal thymus-induced immune tolerance of MG patients in a molecular phenotype and physiological function, so that a cell model closest to a real clinical state is provided for exploring a myasthenia gravis occurrence mechanism.

The present disclosure relates to certain compositions, kits, devices, systems and methods, e.g., certain compositions, kits, devices, systems and methods for assessing methylation status, and / or assessing colorectal cancer and / or advanced adenoma in a subject. In particular aspects, provided herein are compositions, kits, devices, systems and methods for assessing colorectal cancer and / or advanced adenoma in a subject based on assessing methylation status of selected target polynucleotide sequences, e.g., target genomic DNA sequences, from the subject.

A method for differential diagnosis of gallbladder adenoma and cholesterol polyps based on the fusion of deep learning and clinical features in ultrasound images includes: performing deep learning on ultrasound images using a deep learning network to output an adenoma / polyp risk score; the deep learning network is selected from one of VGG, ResNet, DenseNet, GoogLeNet, Vision Transformer, and Inception; the adenoma / polyp risk score and clinical features are input into a trained machine learning model for learning to obtain the final probability of identifying the polyp as a gallbladder adenoma rather than a cholesterol polyp; the clinical features include: echo intensity, maximum polyp diameter, and age; the machine learning model is selected from one of Logistic Regression, Gradient Boosting, K-nearest neighbors, Gaussian naïve Bayes, AdaBoost, Random Forest, ExtraTrees, and SVM.

Devices for improving adenoma detection during colonoscopy, and more particularly, to devices that are positionable at a distal end of an endoscope and are structured or configured to expand and retract upon longitudinal or rotational displacement of at least a portion of the device about the endoscope.

The invention relates to medical technology and can be used in urology for drainage and treatment for the prophylaxis of postoperative complications in the prostate and urethra after surgical treatment of prostate adenoma.Summary of the invention consists in that the device comprises four symmetrical tubes (1, 2, 3, and 13) of different diameters and connected on a line along their longitudinal axis, one end (8) of the device is made blunt, the tubes at the opposite end (9) of the device are separate, each end of which is equipped with a branch pipe. In the tube (1) of a larger diameter are made three channels (4, 5, 6), where one channel (4) communicates with an elastic balloon (7) placed at the blunt end (8) of the device, and two channels (5, 6) pass through the balloon (7) and each ends with an opening (11) on the sides of the blunt end (8). The tube (2) is made of a smaller diameter than the tube (1) and ends with multiple holes (10) on the side of the blunt end (8) under the elastic balloon (7). The tube (3) is made with the smallest diameter and with the blind end under the elastic balloon (7), and along the path of tube (3) in its wall are made 4…5 holes (12) at a distance of 5…6 cm from each other. The tube (13) is made blind, the diameter of which is equal to the diameter of the tube (1), and in this tube (13) is placed an insulated coaxial cable (14) with one end reaching the balloon (7), where the corresponding end of the cable (14) is equipped with a coaxial dipole antenna (15), and the opposite end of the cable (14) is equipped with a connector (16) for connection to a microwave generator, in the tube (13) is also placed an optical fiber (17) with one end reaching the balloon (7), where the corresponding end of the optical fiber (17) is equipped with a transmitter with a diffuser emitter (18) for infrared waves, and the opposite end of the optical fiber (17) is equipped with a connector (19) for connection to an infrared wave generator. The device has a diameter of 28…30 Fr and is made of silicone or natural latex coated with polytetrafluoroethylene.

The application belongs to the biological field and particularly relates to application of organic medlar polysaccharide in prevention and treatment of colorectal adenoma type polyps. Through in-vivo animal experiments, it is found that compared with common medlar polysaccharide, the organic medlar polysaccharide can significantly reduce the lesion area of the colorectal adenoma type polyps, can be used as a natural preparation for preventing and treating the colorectal adenoma type polyps, can effectively improve the colorectal adenoma type polyps, and can be used for reducing the incidence and progression risk of the colorectal adenoma type polyps.

The invention relates to medical technology and can be used in urology for drainage for the purposes of prophylaxis of postoperative complications in the prostate and urethra after surgical treatment of prostate adenoma.Summary of the invention consists in that the device comprises three symmetrical tubes (1, 2 and 3) of varying diameters and joined on a line along their longitudinal axis. One end (8) of the device is made blunt, the tubes at the opposite end (9) of the device are separate, each end of which is equipped with a connection, in the tube (1) of a larger diameter are made three channels (4, 5, 6), where one channel (4) communicates with an elastic balloon (7), placed at the blunt end (8) of the device, and two channels (5, 6) pass through the balloon (7) and each ends with an opening (11) on the sides of the blunt end (8). The tube (2) is made of a smaller diameter than the tube (1) and ends with multiple holes (10) on the side of the blunt end (8) under the elastic balloon (7). The tube (3) is made with the smallest diameter and is made with the blind end under the elastic balloon (7), and along the path of the tube (3) in its wall are made 4…5 holes (12) at a distance of 5…6 cm from each other, at the same time the device has a diameter of 28…30 Fr and is made of silicone or natural latex coated with polytetrafluoroethylene.

This invention discloses a deep learning-based auxiliary diagnostic device and method for benign and malignant ampullary adenomas, comprising the following modules: an image preprocessing module, an image quality assessment module, and an image lesion nature assessment module. The image preprocessing module acquires and preprocesses endoscopic images of the patient; the image quality assessment module determines whether the valid examination images output after image preprocessing contain a clear nipple, thus achieving quality screening of the diagnostic images; the image lesion nature assessment module determines the benign or malignant nature of the lesions in the images containing clear nipples output by the image quality assessment module. This invention, by adding an image quality assessment module, solves the problem of low-quality images interfering with diagnostic accuracy in traditional diagnosis, thereby improving the efficiency and accuracy of benign and malignant ampullary adenomas.

The application belongs to the technical field of computer hospital, and particularly relates to a method for establishing an early diagnosis model of intestinal adenocarcinoma based on peripheral blood detection, which comprises the following steps: collecting serum samples; detecting by using a Raman spectrometer; performing graphic analysis and data processing on the collected Raman spectrum signals; and constructing a deep learning model architecture. The application successfully constructs a natural language model suitable for Raman spectrum data processing and analysis, and further constructs a recognition model of patients with colorectal adenoma and adenocarcinoma. The application successfully develops a screening method for colorectal adenoma and adenocarcinoma based on peripheral blood Raman spectrum detection.