13 results about "Phytoestrogens" patented technology

The invention relates to an intelligent response skin care composition as well as a preparation method and application thereof. The composition comprises freeze-dried phytoestrogen powder, poly (N-isopropylacrylamide), chitosan, a humectant and vitamin C, and the water dispersibility and skin absorbability of the composition are remarkably improved. Poly (N-isopropylacrylamide) and chitosan respectively endow the composition with temperature and pH response characteristics, and can intelligently slowly release and regulate and control release of active ingredients according to skin environment changes (such as high temperature and sweat pH rise), thereby achieving the effects of long-acting moisturizing, oil resistance, aging resistance and the like. Experiments show that the moisturizing rate of the composition in a high-temperature environment within 3 hours exceeds 65%, the wrinkle reduction rate within 3 months reaches 41.2%, the composition is suitable for facial masks, essence and other dosage forms, the problem that the skin barrier function is reduced due to high temperature in summer is solved, and the composition has safety and precise skin care effects.

The invention relates to the technical field of medical preparations, and particularly discloses a selenium-based anti-postmenopausal osteoporosis medicine and a preparation method and application thereof.The selenium-based anti-postmenopausal osteoporosis medicine comprises a main active component, a secondary active component and an auxiliary active component, the main active component is a nano-selenium-phytoestrogen compound and is formed by covalent coupling of selenomethionine and soy isoflavone, the particle size of the main active component is 50-200 nm, and the particle size of the auxiliary active component is 100-200 nm; the mass of the selenium element accounts for 5-30% of the mass of the compound; the auxiliary active component is a collagen peptide-calcium chelate and is prepared from marine collagen peptide and calcium citrate through chelation reaction, and the mass ratio of the calcium element to the collagen peptide is (1: 3)-(1: 5); the targeted delivery carrier is folic acid modified chitosan nanoparticles and is used for loading the main active component and the auxiliary active component; the auxiliary materials comprise a disintegrating agent, a lubricating agent and a pH-sensitive enteric coating material; through the synergistic effect of the main active ingredient nano-selenium-phytoestrogen compound and the auxiliary active ingredient collagen peptide-calcium chelate, bone formation can be promoted and bone resorption can be inhibited at the same time, and dual-function treatment is achieved.

This invention relates to a method for preparing a skincare composition, its delivery system, and its applications. The method involves preparing a nanoemulsion carrier comprising phospholipid-amine bond-polyethylene glycol, chitosan, etc.; mixing phytoestrogens powder, moisturizers, whitening ingredients, etc., to obtain an active ingredient mixture; integrating the two and adding a penetration enhancer to form a skincare composition. This composition exhibits excellent active ingredient permeability and good stability in in vitro transdermal absorption tests; skin moisture content remains stable above 60% after 4 hours; significant improvement in skin brightness is observed in whitening tests; and in anti-aging performance tests, facial wrinkles are reduced by approximately 40% after 3 months of use, with a good user experience and no adverse reactions, demonstrating broad market application prospects.

The invention relates to a moisturizing and whitening composition for promoting permeation and absorption and application of the moisturizing and whitening composition in skin care products. The composition comprises phospholipid polyethylene glycol carboxyl, limonene, menthone and other penetration enhancer components, and by optimizing the composition and proportion of the penetration enhancer, the skin permeability of phytoestrogen is remarkably improved. After a skin care product prepared from the composition is used for 4 hours, the water content of skin is stably maintained to be 60% or above, meanwhile, the skin care product is excellent in whitening, skin elasticity improving and other aspects, the skin brightness change (L) is remarkably improved, and the skin elasticity growth rate exceeds 26% after the skin care product is used for 5 weeks. The composition solves the problem of low permeation efficiency of phytoestrogen, realizes the effects of long-acting moisturizing, whitening and the like, has good use experience, is free of irritation and anaphylaxis, and has a wide market application prospect.

The present invention relates to a moisturizing and whitening composition that promotes osmotic absorption and its use in skin care products. The composition contains permeation enhancers such as phospholipid polyethylene glycol carboxyl, limonene, and menthone. By optimizing the composition and ratio of the permeation enhancers, the skin permeability of phytoestrogens is significantly enhanced. After four hours of use, skin care products prepared with this composition maintain skin moisture content above 60%. They also demonstrate excellent whitening and elasticity enhancement, with significant increases in skin brightness (ΔL) and a skin elasticity growth rate exceeding 26% after five weeks of use. This composition addresses the issue of low phytoestrogens' low permeation efficiency, achieving long-lasting moisturizing and whitening effects. It also offers a positive user experience, is non-irritating, and has broad market application prospects.

This invention provides *Lactobacillus gasseri* and its application in the preparation of phytoestrogens, relating to the field of biofermentation technology. The *Lactobacillus gasseri* is *Lactobacillus gasseri* (…). Lactobacillus gasseri The strain, KMHD3-7519, registered with the China General Microbiological Culture Collection Center (CGMCC) under number CGMCC No. 32351, can increase the content of phytoestrogens in plant extracts. It promotes the conversion of daidzein to daidzein in plant extracts and simultaneously converts daidzein partially to equol, thus increasing the total amount of phytoestrogens in the extract. This invention provides a probiotic capable of simultaneously promoting the conversion of two phytoestrogens, which can be used to produce daidzein, or equol, or simultaneously increase both daidzein and equol, with broad application prospects.

The invention discloses a slow-release nutrition preparation for small needle knife guide in an ovarian reflex region and a preparation method of the slow-release nutrition preparation, and relates to the technical field of medical nutrition preparations. 20 to 30 parts of a slow release carrier; 3-6 parts of an absorption enhancer; 45 to 65 parts of a biocompatible auxiliary material; 1-3 parts of a stabilizer; according to the invention, the D-chiro-inositol is helpful for adjusting hormone balance in vivo and promoting ovarian health; glutathione is a potent antioxidant and protects ovarian cells from oxidative damage; the Q10 coenzyme can enhance cell energy metabolism and improve the ovarian function; soybean isoflavone is phytoestrogen and can simulate the action of estrogen of a human body, the core nutritional ingredients are combined with a slow release carrier prepared from chitosan, sodium alginate and a medicinal fungal polysaccharide compound, slow release of nutrient substances is achieved, action time is prolonged, bioavailability of the nutrient substances is improved, the substances are combined, and the slow release effect is achieved. The nourishing and long-acting protection on the ovary reflex region are realized.

The present invention provides a skin care cosmetic composition containing phytoestrogens, cosmetics and preparation methods thereof. The skin care cosmetic composition containing phytoestrogens includes Cimicifuga racemosa root extract, soybean seed extract, Pueraria root extract, Ginkgo leaf extract, Belamcanda root extract and Rosa roxburghii fruit extract. It has dual anti-aging and light protection effects. The gel mask of the present invention includes a film-like gel carrier, which is prepared by mixed reaction of dialdehyde-modified chitosan and polyethyleneimine (PEI). The adsorption capacity of the essence is large, more essence can be loaded, and the gel has good antibacterial properties, avoiding the use of preservatives such as p-hydroxyacetophenone in cosmetics, and avoiding the harm of preservatives to the human body. The gel prepared by cross-linking chitosan and polyethyleneimine is used for the gel mask, which has a good sustained-release effect, ensures the long-term release of the essence, improves the efficacy of the cosmetics, and avoids the waste of the essence.

A hyaluronic acid hydrogel formulation including phytoestrogen for the treatment of vaginal atrophy and vaginal rejuvenation and production method thereof is provided. The phytoestrogens included in the hyaluronic acid hydrogel formulation are herbal substances that can produce estrogenic effects and have the same structure and functions as estradiol. In this way, risks such as heart attack, stroke, and blood clotting seen in alternative treatment methods including hormone are not encountered.

The invention relates to a preparation method of a skin care composition and a delivery system and application of the skin care composition. The method comprises the following steps: preparing a nano-emulsion carrier containing phospholipid-amine bond-polyethylene glycol, chitosan and the like; mixing the phytoestrogen powder, the humectant, the whitening component and the like to obtain an active component mixture; and integrating the two components, and adding a penetration enhancer to form the skin care product composition. The composition shows excellent active ingredient transmittance in an in-vitro transdermal absorption test, and is good in stability; the water content of the skin is stably kept above 60% after 4 hours; the skin brightness change advantage in a whitening test is obvious; in an anti-aging performance test, the reduction rate of facial wrinkles can reach about 40% after the facial mask is used for 3 months, and the facial mask is good in use experience, free of uncomfortable reaction and wide in market application prospect.

The invention relates to the technical field of feed additives. The invention provides a composition for producing selenium-enriched snowflake beef, a functional feed additive prepared from the composition and application of the functional feed additive. Comprising rapeseed oil, soybean oil, palm oil, linseeds, fructus perillae, semen raphani, platycladus orientalis kernels, fennel, fructus psoraleae, pumpkin seeds, semen cassiae, fructus arctii, semen plantaginis, common fenugreek seeds, semen cuscutae, fructus cnidii, cardamine violifolia powder, cortex magnoliae officinalis, cortex cinnamomi, haws, pericarpium citri reticulatae, pericarpium citri reticulatae viride, rhizoma atractylodis, cyrtomium fortunei, herba artemisiae scopariae, bile acid, soybean phospholipid, cellulase, fatty acid synthetase, vitamin E, vitamin D, zeolite powder and the like. Lipase, polyunsaturated fatty acid, phytoestrogen and the like contained in the traditional Chinese veterinary medicine seeds are utilized to regulate fat metabolism of an organism and increase the content of high-density lipoprotein, and traditional Chinese veterinary medicines for warming and nourishing liver and kidney and soothing liver-gallbladder are fused to enhance liver and kidney functions of the organism, increase biliary secretion and cooperatively promote digestion and absorption of lipid and formation of snowflake beef.

The present invention relates to a method for preparing a liposomal pomegranate extract containing phytoestrogen, and more specifically, when a pomegranate extract is prepared using a two-stage fermentation alcohol with a specific concentration and a nano-emulsion technique is used to perform nano-sized liposomal treatment, active ingredients such as phytoestrogen in the pomegranate extract are significantly increased, and thus, the amount of the active ingredients such as the phytoestrogen in the pomegranate extract is significantly increased, and the amount of the active ingredients such as the phytoestrogen in the pomegranate extract is significantly reduced. In addition, the stability of the active ingredients is maintained for a long period of time, so that the pomegranate extract (ESTROBAL) prepared by the preparation method of the present invention can be effectively used as a component of a health-care functional food or a common food which contributes to improving female climacteric symptoms and symptoms caused by estrogen imbalance.

An aspect relates to a composition for the prevention, amelioration or treatment of menopausal syndrome, bone diseases, and / or dyslipidemia in women, the composition comprising a fermented Pueraria lobata root extract and a fermented Glycine max (L.) Merrill extract. The composition according to an aspect comprises: a Pueraria lobata root extract or a fermented product thereof; and a Glycine max (L.) Merrill extract or a fermented product thereof, which are familiar natural substances, thereby including both glycosides and aglycones of various phytoestrogens. Therefore, the composition has an excellent in vivo absorption rate and excellent efficacy, and thus has an excellent effect of preventing, ameliorating or treating menopausal syndrome, bone diseases, and / or dyslipidemia in women. The composition can be used as a highly palatable, low-dose, high-efficiency product as compared with existing products that have been proven to help menopausal women's health, and can secure excellent competitiveness in the domestic and international markets for women's health functional foods.