112 results about "Alternative treatment" patented technology

A wound treatment device for treating damaged body tissue comprising an encapsulating member having a size and shape capable of being attached to a patient to encapsulate a wound. A fluid communication member is provided for introducing treatment fluid within the encapsulating means for treatment of the wound. The fluid communication member is connected with a supply means for supplying treatment fluid thereto. The fluid communication member is capable of simultaneously transmitting multiple treatment fluids from the supply means into said encapsulating member. The inner surface of the wall of the encapsulating member is textured to allow fluid flow across the wound. The encapsulating member is also formed from a clear material to permit continuous visual inspection of the wound while maintaining a sterile environment.

The invention describes compounds, compositions and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

The present invention describes compounds, compositions and methods of using the same comprising lysine covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

The invention describes compounds, compositions and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

A method for dispensing alternative prescription products to a patient to provide the patient alternative treatment options and increase treatment protocol compliance. After a patient is diagnosed with a medical condition requiring treatment with a prescription product, the patient is provided with a kit containing a multiple continuous positive airway CPAP interfaces designed to adapt to a plurality of different facial features. Instead of being custom fitted by a CPAP interface specialist, the patient is given multiple CPAP interfaces to try and select the CPAP interface most desirable to the patient. The patient indicates the most desirable CPAP interface and, after a predetermined period of time, the patient is provided with a new CPAP interface matching the most desirable CPAP interface selected by the patient.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

This invention describes a system for generating multiple simultaneous tunable electron and photon beams and monochromatic x-rays for all field simultaneous radiation therapy (AFSRT), tumor specific AFSRT and screening for concealed elements worn on to the body or contained in a container. Inverse Compton scattering renders variable energy spent electron and tunable monochromatic x-rays. It's spent electron beam is reused for radiation with electron beam or to generate photon beam. Tumor specific radiation with Auger transformation radiation is facilitated by exposing high affinity tumor bound heavy elements with external monochromatic x-rays. Heavy elements like directly iodinated steroid molecule that has high affinity binding to estrogen receptor in breast cancer and to iodinated testosterone in prostate cancer or with directly implanted nanoparticles into the tumor are exposed with tuned external monochromatic x-rays for tumor specific radiation therapy. Likewise, screening element's atom's k, l, m, n shell specific Auger transformation radiation generated by its exposure to external monochromatic x-rays is used to screen for concealed objects. Multiple beam segments from a beam storage ring or from octagonal beam lines are simultaneously switched on for simultaneous radiation with multiple beams. The beam on time to expose a tumor or an object is only a few seconds. It also facilitates breathing synchronized radiation therapy. The intensity modulated radiation therapy (IMRT) and intensity modulated screening for concealed objects (IMSFCO) is rendered by varying beam intensities of multiple simultaneous beams. The isocentric additive high dose rate from simultaneously converging multiple beams, the concomitant hyperthermia and chemotherapy and tumor specific radiation therapy and the AFSRT's very low radiation to the normal tissue all are used to treat a tumor with lower radiation dose and to treat a radioresistant and multiple times recurrent tumors that heave no other alternative treatments.

The present invention describes compounds, compositions and methods of using the same comprising lysine covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

A wound treatment device for treating damaged body tissue comprising an encapsulating member having a size and shape capable of being attached to a patient to encapsulate a wound. A fluid communication member is provided for introducing treatment fluid within the encapsulating means for treatment of the wound. The fluid communication member is connected with a supply means for supplying treatment fluid thereto. The fluid communication member is capable of simultaneously transmitting multiple treatment fluids from the supply means into said encapsulating member. The inner surface of the wall of the encapsulating member is textured to allow fluid flow across the wound. The encapsulating member is also formed from a clear material to permit continuous visual inspection of the wound while maintaining a sterile environment.

External beam radiotherapy treatment workflow scheduling and optimization. The system and method provides for determining a workflow metamodel, receiving a treatment plan, determining a treatment schedule corresponding to the workflow metamodel and treatment plan, taking into account saftety by determining alternative treatment schedules, computing a safety index, and selecting one alternative treatment schedule that satisfies a safety threshold and that provides an optimal schedule.

The invention discloses a processing method of precooked coarse grains simultaneously boiled and cooked with rice, and belongs to the technical field of deep processing of agricultural products. The method comprises the following steps: screening mixed beans or coarse grains as a raw material, cleaning, immersing, carrying out fumigating precuring treatment on the raw material by using steam to obtain a precooked raw material, carrying out loosening and microwave slaking alternative treatment on the precooked raw material, cooling, and packaging to obtain precooked coarse grains. The method has the advantages of low production cost of the processing process, short processing period, and products processed through the method have the characteristics of maintenance of the original appearance form, less nutrition component loss, maintenance of the original smell of coarse grains, storage and transportation benefiting, and adaptation to the industrialized popularization.

The invention relates to a device and a method for producing containers, such as e.g. bottles, in which different types of bottles are produced. Alternative treatment methods are used depending on the type of bottle to be produced. For example, a cooling treatment is carried out when producing bottles for carbonated beverages and a sterilisation treatment is carried out when producing bottles for non-carbonated beverages.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

A method for radiation therapy treatment plan optimization, comprising generating a first radiation therapy treatment plan for a patient using a selected treatment type from a database and optimizing the first radiation therapy treatment plan. A selection of metrics from the first radiation therapy treatment plan are identified and compared to metrics from aggregated prior patient records selected from the database. At least one parameter is identified that affects the ability of the first radiation therapy treatment plan to meet an identified metric. The at least one parameter for the identified metric is compared to at least one parameter for a competing metric and at least one alternative treatment step for the treatment plan is determined that will change the identified at least one parameter to improve the identified metric.

External beam radiotherapy treatment workflow scheduling and optimization. The system and method provides for determining a workflow metamodel, receiving a treatment plan, determining a treatment schedule corresponding to the workflow metamodel and treatment plan, taking into account safety by determining alternative treatment schedules, computing a safety index, and selecting one alternative treatment schedule that satisfies a safety threshold and that provides an optimal schedule.

The invention is directed to a method of removing a deleterious substance bound to a protein in blood of a patient by introducing a displacer substance into the blood under conditions in which the displacer substance replaces deleterious substance bound to the protein, thereby resulting in additional unbound deleterious substance in the blood, and removing unbound deleterious substance from the blood by extracorporeal renal replacement treatment.

A patient treatment system includes one or more automated patient transporters configured to move a patient from a preparation area to one of a plurality of alternative treatment areas, and to position the patient relative to a therapeutic radiation beam. Both transportation of the patient and positioning of the patient are optionally performed while the patient is secured to one of the patient transporters. A control system may be used to both position and transport the patient responsive to a patient treatment plan.

Methods and kits for determining appropriate treatment for illnesses in humans or animals are disclosed. The method includes: providing a test kit containing a random arrangement of drug(s) and placebo(s) and / or alternative treatment(s) along with a questionnaire or other instrument designed to elicit data concerning the safety, efficacy and desirability of a treatment; administering the drug(s) and placebo(s) and / or alternative treatments to each member of the pool in a random, double blind fashion and following up on patient outcomes as appropriate post-study; assembling a database from the completed pool questionnaires and revealing the random schedule to uncover drug and placebo treatment periods; providing the same kit to a patient in need of the same treatment and comparing the results obtained from the single patient trial with those obtained from the pool to determine an optimal treatment for the patient with the drug; and administering a treatment consistent with the optimal treatment.

Methods and kits for determining appropriate treatment for illnesses in humans or animals are disclosed. The method includes:providing a test kit containing a random arrangement of drug(s) and placebo(s) and / or alternative treatment(s) along with a questionnaire or other instrument designed to elicit data concerning the safety, efficacy and desirability of a treatment;administering the drug(s) and placebo(s) and / or alternative treatments to each member of the pool in a random, double blind fashion and following up on patient outcomes as appropriate post-study;assembling a database from the completed pool questionnaires and revealing the random schedule to uncover drug and placebo treatment periods;providing the same kit to a patient in need of the same treatment and comparing the results obtained from the single patient trial with those obtained from the pool to determine an optimal treatment for the patient with the drug; andadministering a treatment consistent with the optimal treatment.

A computer implemented method, apparatus, and computer program product for modifying neuropsychiatric treatment plans based on efficacy of treatment. A current treatment plan comprising a first set of therapies to treat a set of neuropsychiatric conditions and portions of the medical literature associated with the set of neuropsychiatric conditions is retrieved. A set of brain scans of the patient is analyzed to determine a set of changes over time associated with the set of neuropsychiatric conditions. The portions of the medical literature and the set of changes are analyzed to determine a patient rate of response to the treatment plan. If the patient rate of response falls below a threshold expected rate, a set of alternative treatments for the patient is identified. A modified treatment plan is generated using the set of alternative treatments.

The invention relates to a device and a method for the production of containers, such as bottles, wherein different types of bottles are produced. Depending on the type of bottle to be produced, alternative treatment methods are used. If bottles for carbonated drinks are to be produced, a cooling treatment is used. If bottles for non-carbonated drinks are to be produced, a sterilization treatmentis performed.

In a disclosed embodiment, a chemical process has a pair of beds, with each of said beds having at least one connection to receive a source of gas, and for delivering gas downstream. Each of the beds includes chemical treatment elements. The system includes a connection to a source of a gas to be treated, and a connection for receiving treated gas to be delivered to a downstream use, a connection to a source of a cleaning gas, and a connection to deliver the cleaning gas downstream. A rotary valve includes a rotary actuator for rotating a valve to selectively switch each of the beds between the several connections.

A method for predicting with high specificity from RTPCR detected markers if a patent is likely to respond to docetaxel treatment is disclosed. RTPCR detects the presence of absence of certain mutations due to fusion events. Together, with other protein markers, additional stratification is possible to identify patents suited for docetaxel therapy as opposed to for alternative treatments.

The invention discloses a method for controlling solanum rostratum by pasture combination. According to the method, the pasture combination of sweet clover, wheatgrass and Chinese wildrye are used to prevent invasion of solanum rostratum; the pasture combination is planted in the easily-invaded natural grassland ecosystem in order to continuously control invasion of solanum rostratum in many years. The sweet clover is a type which can resist solanum rostratum in the invasion habitat, grows in the grassland that solanum rostratum likes and has growth advantage in struggle for existence; the wheatgrass and Chinese wildrye can continuously inhibit growth of solanum rostratum in many years after alternative treatment; due to plantation, rational arrangement and scientific management, the sweet clover pasture combination can play a role in easily-invaded solanum rostratum and invaded ecosystem, inhibit solanum rostratum from quickly growing in natural grassland to occupy space continuously and effectively, and provide basic guarantee for preventing and sustainably treating invasion of alien invasive species such as solanum.

The invention discloses a deep treatment and recycling method for municipal sewage on the basis of biochemical and electrolytic technologies. The deep treatment and recycling method comprises the following steps: (1) anaerobic treatment; (2) anoxic and aerobic treatment; (3) secondary precipitation; (4) nano-catalytic electrolysis (NCE); (5) flocculating precipitation or coagulating precipitation; and (6) filtering. The deep treatment and recycling method comprises the detailed steps of firstly adopting anaerobic treatment for the sewage, then carrying out anoxic and aerobic alternative treatment and secondary precipitation, and then adopting a combined process of electrolysis, flocculating precipitation or coagulating precipitation and filtering to lead the municipal sewage to be treated and reach surface fourth-type or third-type water quality standard. The deep treatment and recycling method disclosed by the invention has the advantages that COD (Chemical Oxygen Demand), BOD (Biochemical Oxygen Demand), chromaticity, ammonia nitrogen and total nitrogen are removed by electrolysis; the COD, petroleum and vegetable oil are removed by flocculating precipitation or coagulating precipitation, and simultaneously phosphorus, partial organic matters and total nitrogen are removed; and solid particulate matters (SS) are removed by filtering, and the filtered water reaches the surface fourth-type or third-type water quality standard.

The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.

The pharmaceutical composition comprising the compound of the invention having 8-azaprostaglandin skeleton represented by formula (I)(wherein, all the symbols have the same meanings as that of the specification) a salt thereof, a solvate thereof or a cyclodextrin clathrate thereof, or a prodrug thereof and them as active ingredient have EP4 agonistic action and thus are considered useful for the prevention and / or treatment of immunological diseases, asthma, neuronal cell death, arthritis, lung failure, pulmonary fibrosis, pulmonary emphysema, bronchitis, chronic obstructive pulmonary disease, liver damage, acute hepatitis, nephritis, renal insufficiency, hypertension, myocardial ischemia, systemic inflammatory response syndrome, sepsis, hemophagous syndrome, macrophage activation syndrome, Still's disease, Kawasaki disease, burn, systemic granulomatosis, ulcerative colitis, Crohn's disease, hypercytokinemia at dialysis, multiple organ failure, shock and glaucoma, etc. Furthermore, the compounds also have an action of accelerating bone formation, so it is expected to be useful for the prevention and / or treatment of diseases associated with loss in bone mass, for example, primary osteoporosis, secondary osteoporosis, bone metastasis of cancer, hypercalcemia, Paget's disease, bone loss, osteonecrosis, bone formation after bone operation, alternative treatment for bone grafting.

The invention provides a method for constructing a model of oriented differentiation of embryonic stem (ES) cells into testicular interstitial cells. The method comprises the following steps of: firstly, cotransfecting a steroidogenic factor 1 and a luteinizing hormone receptor plasmid into an ES cell; then inducing the ES cell by a compound or growth factor to directionally differentiate the ES cell into the testicular interstitial cell. In the invention, the construction and the application of the model for in-vitro oriented differentiation of the stem cells into the testicular interstitialcells are demonstrated at the cellular level; a great deal of biology information is discussed initially; the constructed cell model is a substituted model for researching the influencing factor of the secretory regulation function of the testicular interstitial cell and can be used for initially selecting and evaluating the medical effect of the pharmaceutical drug using the testicular interstitial cell as the target cells; the transplanting of the testicular interstitial cell differentiated from the stem cells is used as a new method for supplying testosterone, and the application prospect of the renewable alternative treatment of the testicular interstitial cell is improved.

Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.

The invention discloses a preparation method for a copper sulphide nano-material with near infrared absorption performance and near infrared light sterilizing capacity of the copper sulphide nano-material to Escherichia coli and staphylococcus aureus, and belongs to the fields of metal nano-material preparation and biomedical application. The copper sulphide nano-material is synthesized by adopting a water bath method; the reaction conditions are mild; the method is simple; the copper sulphide nano-material which are uniform in particular sizes and high in dispersibility and have strong absorbing performance at about 1,000 nm is prepared successfully by regulating temperature, pH and protein using amount; under the irradiation of near infrared light of 980 nm, near infrared light can be effectively converted into heat energy by the material, so that the Escherichia coli and the staphylococcus aureus can be killed within several minutes; an alternative treatment mode can be provided for clinical treatment of skin diseases because of unique photo-thermal sterilizing capacity and low cost of the material.