10 results about "Isotopic tracer" patented technology

Various methods and compositions of treating 4-hydroxyphenylpyruvate dioxygenase-like (HPDL)-related diseases or disorders are presented herein. Also presented herein are methods of increasing CoQ10 biosynthesis, and methods of determining whether a subject will benefit from a CoQ10 or CoQ10 alternative treatment. Also presented herein are pharmaceutical compositions and dosage forms comprising 4-hydroxymandelic acid (4-HMA), and / or its metabolites. Further presented herein are compounds that inhibit 4-hydroxyphenylpyruvate dioxygenase-like (HPDL). Further presented herein are methods of identifying and / or assessing modulators of HPDL. Yet further presented herein are example methods and systems for isotopic labelling in cells by metabolizing cells in the presence of gaseous isotopic tracer.

A kind of mouth of a river backfill drainage pipe network detection device and detection method, detection device includes elbow and shaft;The end of elbow is provided with plugging pipe, the other end is provided with connecting pipe, the shaft is installed on connecting pipe.Detection method includes the following steps: S0: determine suspected well;S1: assemble detection device;S2: detection device is put into water, after plugging pipe is aimed at the mouth of a river, it is inserted and plugged, so that detection device and the pipeline in suspected well form a communicating vessel structure;S3: water is taken from the field surface water body using water taking tool, after adding isotope tracer, mixed water body is poured into detection device from the top of shaft, so that mixed water body enters suspected well;S4: water quality sampling is carried out in suspected well and is detected, when the tracer put in is detected in water sample, then it can be judged that the inspection well is one of the paths of the mouth of a river as surface water invasion;S5: repeat steps S2 to step S4 to detect the water quality of multiple suspected wells.

The present application belongs to the field of well logging operation, and particularly relates to a wellhead releasing device and a small-bore injection well logging method. In view of the problem that the conventional isotope tracing profile logging technology cannot meet the tracing profile logging requirements of the small-bore double-layer tubing injection well, a small-diameter multi-parameter logging instrument is optimized. Firstly, a radioactive isotope tracer wellhead releasing device is developed, which releases the isotope tracer into the well sections that are not communicated with each other by using the injection pressure difference between different injection sections and installing the wellhead releasing device on the wellhead Christmas tree. Secondly, the isotope tracer anti-dispersion method is studied, and the isotope tracer parameters are optimized, so as to improve the coagulation ability of the liquid isotope tracer in long-distance migration, thereby improving the logging interpretation accuracy. Thirdly, the releasing device and the isotope tracer preparation method are applied to improve the construction process, so as to complete the logging operation and meet the application and popularization.

The invention relates to the technical field of smart cities, and discloses a smart city happiness assessment system and method based on multi-dimensional perception, and the system comprises a data collection module which is configured to synchronously collect the tracer concentration time sequence data of an isotopic tracer released by an active isotopic tracer release unit in a preset city space, and concentration time series data of the plurality of volatile organic compounds detected by the chemical sniffer; and the signal source attribution module is connected with the data acquisition module and is configured to be based on the tracer concentration time sequence data and the concentration time sequence data of the volatile organic compound. The data acquisition module is configured for synchronous acquisition with high time resolution, and the signal source attribution module and the happiness evaluation module are used for continuous data processing and index calculation, so that continuous monitoring of group states is realized, and group emotion fluctuation caused by specific events or environmental changes can be captured more timely.

The application provides a goaf cross-medium seepage-stress-structure coupling experimental device and method, relates to the technical field of rock mass mechanics testing, and comprises a structure simulation system, a gradient force loading system and a tracing seepage system; goaf accumulation rock samples are coaxially stacked on in-situ rock layers, and the in-situ rock layers are configured to simulate the floor rock layer close to the coal seam in the real goaf and are internally provided with water outlet micro flow channels. The gradient force loading system is used for dynamically applying uniform or gradient distribution axial pressure and confining pressure to the rock sample. The tracing seepage system comprises a water storage tank containing seepage water with an isotopic tracer and multiple camera modules. The internal fracture structure characteristics of the rock sample are output through the transparent shell, the tracing signal generated by the isotopic tracer and the seepage images collected by the camera modules. The problems that the existing experimental structure cannot truly reproduce the seepage-stress-structure three-field coupling and cannot accurately realize the internal fracture three-dimensional visualization and quantitative characterization are solved.

The invention provides a method for determining a sliding surface or position of a landslide by using a radioisotope tracer. The method comprises the following steps: firstly, preliminarily delineating the periphery of a landslide, then arranging three exploration lines, drilling a radioactive isotope tracer feeding hole and a plurality of observation holes in the exploration lines, and putting a layered water taking device into each observation hole; a radioactive isotope tracer is dissolved in water and then put into the source putting hole, water in the layered water taking device is extracted at regular time to detect the radioactivity of the water, after the radioactivity is detected, the layered water taking device in the observation hole is taken out, and the radioactive concentration of accumulated water in each layer is detected; and then drilling a soil hole at the upstream of each observation hole for drilling and coring to detect the radioactivity in the rock core, and accurately determining the position of the sliding surface or zone of the landslide according to the position and the concentration of the radioactivity in the accumulated water and the rock core. According to the method, the problem that the position of the sliding zone is difficult to determine in landslide investigation is effectively solved, the landslide investigation quality and efficiency are improved, and more accurate data are provided for subsequent treatment design.

The invention discloses a visual experimental device, system and experimental method for conventional triaxial hydraulic fracturing, which can simulate and visualize the triaxial hydraulic fracturing process under controllable conditions by applying confining pressure and axial stress to an experimental sample and injecting fracturing fluid to simulate fracturing, thereby improving the predictability and efficiency of field operation. A radioisotope tracer detection imaging technology is used for monitoring the crack expansion process in real time, direct crack dynamic data are provided through comprehensive and real-time monitoring of a radioactivity detection probe and a detection imaging system, rock responses under different fracturing parameters can be predicted, and therefore a fracturing scheme with the highest cost benefit is selected; according to the invention, the formation and expansion of cracks in the experimental rock sample can be comprehensively observed in real time; the device is suitable for the industries of rock mechanics and petroleum engineering, and is used for simulating and monitoring the cracking and crack propagation process of experimental rock samples.

The invention discloses a method for tracing the hydrothermal activity of a sedimentary basin, and belongs to the technical field of geochemistry and isotopic tracing. The tracing method comprises the following steps: pre-treating a mixed mineral sample, separating and purifying a lithium element, and measuring a delta 7 Licarb value; carrying out correlation analysis on the delta 7 Licarb value and the main trace element characteristics of the sample; correcting the measured delta 7 Licarb value of the mixed mineral sample; performing correlation analysis on the corrected data of the mixed mineral sample, a hydrothermal activity index and an anti-weathering index; and determining a corrected background value of delta 7Li in the research sequence, and judging a hydrothermal activity enhancement period, a hydrothermal activity weakening period or a non-hydrothermal dominant period by comparing a difference between a lithium isotope ratio of a continuous layer section and a background interval value. The method has the advantages of continuous high resolution, wide temperature range sensitive response, clear mechanism, strong anti-interference capability and strong universality.

The application discloses a kind of sedimentary basin hydrothermal activity tracer method, belong to geochemistry and isotopic tracer field.The tracer method includes the pretreatment of mixed mineral sample, lithium element separation and purification and δ 7 Li carb Value determination;The correlation analysis of δ 7 Li carb Value and the main trace element characteristics of sample;The measurement δ 7 Li carb Value of mixed mineral sample is corrected: the correlation analysis of corrected data of mixed mineral sample and hydrothermal activity index and anti weathering index;Determine the δ 7 Li 校正后 Background value in study sequence, judge hydrothermal activity enhancement period, hydrothermal activity weakening period or non-hydrothermal dominant period by comparing lithium isotopic ratio of continuous section and background interval value difference.The method has the advantages of continuous high resolution, wide temperature range sensitive response, mechanism is clear, strong anti-interference ability and strong universality.

A method of generating biogas includes delivering a feedstock downhole to a coal reservoir, generating biogas within the coal reservoir, and harvesting the biogas. A method of tracing the migration of biogas in a coal reservoir includes delivering a feedstock downhole to a coal reservoir via an injection well, generating biogas within the coal reservoir through microbial action, creating a biogas that is isotopically differentiable from a background gas that is native to the coal reservoir, harvesting the biogas at the injection well and one or more offset wells of the coal reservoir, analyzing the biogas and coal bed methane from the coal reservoir at the injection well and the offset wells, detecting the biogas at the offset wells using isotopic differentiation, and mapping the migration of the biogas from the injection well to the offset wells using the biogas as an isotopic tracer.