The invention discloses a stomachic noodle with sweet potato and matrimony vine. The noodle is prepared from following raw materials in parts by weight: 90 to 120 parts of bread flour, 5 to 10 parts of bucketwheat flour, 10 to 15 parts of konjak flour, 1 to 2 parts of red bean powder, 5 to 10 parts of almond powder, 2 to 4 parts of yolk powder, 1 to 2 parts of wall-broken Ganoderma lucidumspore spore powder, 10 to 15 parts of sweet potato powder, 0.1 to 0.3 parts of iodized salt, 25 to 30 parts of soft water, 4 to 8 parts of composite fruit lyophilized powder, 1 to 2 parts of dried tremella, 2 to 4 parts of carrageenan, 4 to 8 parts of composite Chinese medicine liquid and 0.05 to 0.2 parts of edible sodium carbonate. The noodle has advantages of good mouthfeel, delicious taste, abundant nutrition and also healthcare effect of dietotherapy, and can strengthen stomach and promote digestion, moisten dryness and calm nerves, enhance immunity, enrich and nourish blood, improve resistance, nourish liver and kidney, and boost vital essence and improve eyesight.