41 results about "Pepper extract" patented technology

The invention belongs to the technical field of medicines, and particularly relates to a composition for improving obesity and promoting cardiovascular health as well as a preparation method and application thereof. The composition is prepared from the following components in parts by weight: 5 to 20 parts of glycine betaine, 1 to 5.5 parts of choline chloride, 0.5 to 4 parts of L-theanine, 1 to 15 parts of alpha-ketoglutarate calcium, 0.5 to 3 parts of black ginger extract, 0.05 to 0.25 part of black pepper extract, 0.5 to 3 parts of ginkgo leaf extract and 1 to 6 parts of black garlic juice powder. According to the invention, the eight components are selected and are scientifically combined in an optimal quantity ratio range, and the prepared composition can better reduce the inflammation level of a body, regulate abnormal blood fat, improve the lipid metabolism disorder state and effectively reduce impulsive diet behaviors, so that comprehensive improvement of obesity and cardiovascular related risks is realized, and the health-care effect of a human body is improved. The body is effectively assisted to maintain metabolic health.

This invention discloses a cardioprotective compound composition and its preparation based on improving the absorption rate of coenzyme Q10, relating to the fields of pharmaceuticals and functional foods. The core active ingredients of this composition consist of coenzyme Q10, vitamin E, and black pepper extract, with a specific mass ratio range for each. It can also be combined with pharmaceutically acceptable carriers and antioxidant synergists to prepare various oral formulations. This invention, through the construction of a ternary active component with a specific ratio, achieves in vivo synergistic effects on absorption promotion and antioxidant regeneration, solving the technical problems of low oral bioavailability and insufficient accumulation of myocardial-targeted activity in existing coenzyme Q10 preparations. It significantly improves the conversion efficiency of coenzyme Q10 into a usable active form for cardiomyocytes and can be widely applied in the preparation of drugs and functional foods for the prevention or treatment of heart diseases.

The invention discloses a black pepper extract-containing composition capable of promoting intestinal digestion and absorption and a cat food, and relates to the technical field of animal foods.The composition is prepared by compounding fish oil, krill oil, sunflower seed oil and linseed oil according to a specific proportion based on compound functional grease and natural plant extracts in a scientific proportion; according to the invention, the ratio of omega6 fatty acid to omega3 fatty acid is optimized to an ideal range of (2.5-3.2): 1, black pepper extract with functions of promoting digestion and regulating flora is synergistically added, and through combination of scientifically proportioned functional components and an advanced process, an'intestinal tract-microorganism-metabolism 'experiment verifies that digestion and absorption of cat nutrition are realized, and the effect of promoting digestion and regulating flora is achieved. Meanwhile, the multi-dimensional and systematic improvement of oxidation resistance, inflammation resistance, immunity improvement and metabolism functions is achieved.

The application discloses a driver special anti-drowsy spicy water and a preparation method and application thereof, and relates to the technical field of functional drinks.The raw material components of the spicy water include aged old-lake sour water, self-made iodine-free acid salt water, pepper extract and trace chicken essence;the self-made iodine-free acid salt water is prepared by mixing 92 parts of drinking water and 8 parts of iodine-free salt by weight;the salt content of the finished product is 0.5%-0.8%, the pH value is 3.0-3.6, and the spiciness of the pepper extract is 10000-40000 SHU.The application further discloses a preparation method of the spicy water and an anti-slip light-proof glass bottle packaging structure specially designed for drivers.The natural sour and spicy synergistic stimulation of the aged old-lake sour water and the pepper extract can effectively inhibit the drowsiness of drivers, relieve fatigue driving, and keep the drivers awake for more than 30 minutes after single drinking;the application is suitable for long-distance drivers, and has a remarkable anti-drowsy effect and good driving scene adaptability.

The invention relates to the field of hair growth nutrients, and discloses a nutrient composition for promoting hair growth and a preparation method thereof, the composition comprises a basic hair growth nutrient group and an absorption-promoting synergistic group; the basic hair growth nutrition group comprises the following components in parts by weight: 0.3-0.8 part of ferrous lactate, 2-5 parts of zinc gluconate, 5-8 parts of magnesium stearate, 3-8 parts of a coating material and 17-25 parts of milk mineral salt; the absorption-promoting synergistic group comprises the following components in parts by weight: 0.2-1.5 parts of a black pepper extract, 2-10 parts of lecithin and 2-8 parts of casein phosphopeptides, the black pepper extract and the lecithin are firstly released, an intestinal epithelium channel is opened by utilizing a biological penetration promoting effect, and a pre-permeation state is established; the subsequently released CPP is complexed with divalent metal ions in intestinal juice to prevent precipitation, so that the CPP is synchronously and rapidly absorbed through a pre-opened channel, and the problems of competitive antagonism and difficult absorption of high-dose minerals are effectively solved.

The application provides a muscle building and shaping, fat control composition, a preparation method, application and product, and relates to the field of food technology.The composition according to the application is composed of the following raw materials in parts by weight: 30-100 parts of branched chain amino acid, 1-2 parts of casein hydrolysate, 10-50 parts of collagen peptide powder, 0.4-2 parts of cinnamon powder, 0.5-2 parts of purple tea concentrated powder, 5-10 parts of black pepper extract, 1-2 parts of concentrated freeze-dried watermelon powder and 2-8 parts of d-ribose; wherein the black pepper and ethanol solution are mixed, and the black pepper extract is obtained by means of extraction under the condition of heating and auxiliary microwave treatment. In the composition according to the application, the components interact with each other, and the muscle building, shaping and fat control effects are synergistically improved. The composition according to the application is applied to products with the effects of muscle building, shaping and fat control, and the effects are remarkable.

The present invention discloses a heart-protective complex composition for improving the absorption rate of Coenzyme Q10 and a preparation method thereof, relating to the technical field of medicine and functional foods. The core active ingredients comprise Coenzyme Q10, Vitamin E, and black pepper extract within a specific mass ratio range. Pharmaceutically acceptable carriers and antioxidant synergists may also be combined to prepare various oral dosage forms. By constructing a ternary active component system with a specific ratio, the present invention achieves temporal synergy between absorption promotion and antioxidant regeneration in vivo, thereby solving the technical problems of low oral bioavailability and insufficient myocardial targeted accumulation of existing Coenzyme Q10 preparations. It significantly enhances the conversion efficiency of Coenzyme Q10 into the active form available to myocardial cells, and can be widely used in the preparation of drugs or functional foods for preventing or treating heart diseases.

This invention belongs to the technical field of agricultural product preservation materials. It discloses a slow-release label paper for preserving fruits and vegetables / edible fungi, its preparation method, and its application. The slow-release label paper includes an antibacterial layer (1), a preservation-inducing layer (2), a self-absorbent layer (3), and an ethylene adsorption color-developing printing layer (4). The antibacterial layer (1), the preservation-inducing layer (2), the self-absorbent layer (3), and the ethylene adsorption color-developing printing layer (4) are tightly bonded together from the inside out. This invention provides a label material with preservation effects on agricultural products, especially fruits, vegetables, and edible fungi. It can be applied to fruit and vegetable preservation. Compared with existing technologies, the label of this invention uses natural plant-derived active ingredients (Sichuan pepper extract) to replace chemically synthesized substances, inhibiting the main factors causing fruit and vegetable spoilage at the source, thereby significantly extending the shelf life and maintaining quality.

A composition for improving cognitive performance, enhancing mental clarity, increasing focus, and increasing physical and mental energy is disclosed. The composition includes sufficient amounts of Fermented Green Tea Extract, L Theanine, and Caffeine, Ashwagandha Extract, Black Pepper Extract, Huperzine, Fermented Alpha GPC / Citoline Matrix, Turmeric Root Extract, Lions Mane Extract, Ginkgo Biloba Powder Extract, Panax Ginseng Extract, Rhodiola Extract, Cognitive Probiotic Blend, Folic Acid, Vitamin D3, Vitamin C Powder, Vitamin B12, Vitamin B6, Pantothenic Acid, Vitamin B3 Crystalline Powder, Vitamin B2 Powder, Vitamin B1 HCL, and Biotin.

The invention relates to a spraying type composition for protecting heart and cerebral vessels as well as a preparation method and an application method thereof, and belongs to the technical field of health-care medicines. A formula of the injection type composition for protecting the heart and cerebral vessels comprises the following components in parts by weight: 10-30 parts of a radix astragali extract, 10-30 parts of a rhizoma atractylodis macrocephalae extract, 10-30 parts of a rhizoma polygonati extract, 5-20 parts of a cortex eucommiae extract, 10-30 parts of an oyster extract, 5-20 parts of a herba cistanche extract and 5-10 parts of a composite penetrant. Wherein the formula of the composite penetrating agent comprises the following components in parts by weight: 0.5-1 part of a clove extract, 0.5-2 parts of a pepper extract and 2-9 parts of a chemical penetration enhancer; the composition prepared by the invention has the characteristics of efficient permeability and heart and cerebral vessel protection.

The invention relates to pickled pepper flavor slow release-based vinasse bittern and a preparation method thereof, and relates to the technical field of composite flavor vinasse bittern processing.The preparation method comprises the steps that beeswax, monoglyceride and water are mixed for the first time to obtain a first mixed system, the first mixed system and a pickled pepper extract are mixed for the second time to obtain a second mixed system, and the second mixed system is mixed for the second time to obtain the pickled pepper flavor slow release-based vinasse bittern. The second mixed system is subjected to freeze drying, a pickled pepper flavor carrier is obtained, and based on the total mass of beeswax, monoglyceride and water as 100%, the content of beeswax is 5-15%, the content of monoglyceride is 3-8%, and the content of water is 77-92%; and mixing and stirring the aged vinasse and the pickled pepper flavor carrier according to the mass ratio of (1-2): 1 to obtain the pickled pepper vinasse marinade. The pickled pepper vinasse marinade prepared by the invention simultaneously has pickled pepper lactic acid faint scent and aging vinasse fragrance, and is clear, harmonious and stably fused in flavor.

The invention relates to an acupoint injection composition for enhancing an immune function and a preparation and application method thereof, and belongs to the technical field of health-care medicines. A formula of the acupoint injection composition for enhancing the immune function comprises the following components in parts by weight: 10-30 parts of an angelica sinensis extract, 10-30 parts of a ginseng extract, 10-30 parts of a rhizoma polygonati extract, 5-20 parts of an orange peel extract, 10-30 parts of a spina date seed extract, 5-20 parts of a cistanche deserticola extract, 10-30 parts of a Chinese wolfberry fruit extract and 5-10 parts of a composite penetrant. Wherein the formula of the composite penetrating agent comprises the following components in parts by weight: 0.5-1 part of a clove extract, 0.5-2 parts of a pepper extract and 2-9 parts of a chemical penetration enhancer; the composition prepared by the invention has the characteristics of high permeability and immune function enhancement.

The application discloses creatine composition for improving exercise endurance and strength, and a preparation method and application thereof. The creatine composition comprises creatine, black pepper extract and oyster peptide. The scheme has the effects of significantly enhancing energy systems, promoting anabolism, inhibiting catabolism, reducing oxidative damage and accelerating recovery through the combination of components, and can be effectively used for improving exercise endurance and strength.

This invention discloses an ergothioneine-curcumin synergistic anti-inflammatory and anti-aging composite composition and its preparation method, relating to the fields of biomedicine and functional skincare technology. This invention constructs a ternary nanolipid carrier core-shell hierarchical structure consisting of a hydrophobic core, an interface-enhancing layer, and a hydrophilic shell. The hydrophobic core, formed by hydrogenated lecithin and phytosterols, provides a stable lipid microenvironment for curcumin. The oil-water interface region of the lipid bilayer utilizes its polar gradient to directionally anchor piperine molecules from black pepper extract, allowing piperine to be precisely positioned at the lipid membrane interface. The hydrophilic shell, composed of thiolated hyaluronic acid, covalently connects ergothioneine via thiol-disulfide bonds, stably fixing ergothioneine to the carrier surface. This allows it to exert its antioxidant protective effect upon contact with the skin or mucous membranes, while simultaneously preventing the migration and diffusion of ergothioneine into the inner lipid region. This achieves spatially ordered partitioning and functional synergy of the three active ingredients.

The present disclosure relates to topical skin care compositions that increase the hydration of aging skin, improve the barrier function of aging skin, provide antioxidant protection to aging skin and enhance dermal-epidermal junction health in aging skin. In particular, the disclosure relates to a topical composition comprising (i) one or more collagens; (ii) one or more barrier support agents, preferably linoleic acid and / or linolenic acid; (iii) one or more bio-hydration support agents, preferably a botanical 5a reductase inhibitor comprising butyl avocadate, saw palmetto extract, and / or black pepper extract; (iv) one or more dermal-epidermal junction agents, preferably comprising passiflora edulis seed oil; (v) one or more antioxidants, preferably comprising nelumbo nucifera germ extract and / or vitis vinifera (grape) flower extract; and (vi) hyaluronic acid, hyaluronic acid derivatives or combinations of hyaluronic acid and / or hyaluronic acid derivatives.

The invention relates to the technical field of combination of functional food and traditional Chinese medicine, and particularly discloses a beverage with a function of relieving muscular soreness after exercise and a preparation method thereof, the beverage comprises a white peony root extract, a honey-fried licorice root extract, a turmeric extract and a black pepper extract; the content of glycyrrhizic acid in the honey-fried licorice root extract is lower than 0.1%, and the content of piperine in the black pepper extract is not lower than 98%, and preparing and weighing the white peony root extract, the honey-fried licorice root extract, the turmeric extract and the black pepper extract; mixing with electrolyte and erythritol, and adding purified water to a constant volume to obtain a mixed solution; the mixed liquid is stirred and homogenized, and homogenized liquid is obtained; and performing sterilization treatment on the homogenized liquid, and then performing sterile filling to obtain the beverage. By forming a three-in-one synergistic scheme of spasmolysis, anti-inflammation and synergy, the invention provides the drink for recovering after exercise, which is safe and effective and has an easily accepted taste.

The present invention relates to a composition for improving and / or treating exercise-induced osteoarthritis and a preparation method and application thereof, the composition comprises a protein complex, the protein complex is prepared from a CP complex and a non-denatured type-II collagen (UC-II), and the CP complex is prepared from curcumin and a black pepper extract. The curcumin and the black pepper extract form the CP composition, the CP composition and the non-denatured type II collagen form a protein compound, the gastrointestinal tract digestion retention rate of the non-denatured type II collagen (UC-II) is improved through the formation of the protein compound, and therefore the effect of the non-denatured type II collagen (UC-II) on the immune oral tolerance mechanism is improved.

This invention discloses a garlic-flavored *Pteris vittata* strain and its application in ginseng-inspired crop rotation restoration and reduction of continuous cropping obstacles in *Gastrodia elata*, belonging to the field of agricultural biotechnology. The *Pteris vittata* strain MS-GY-GLY, with accession number CGMCC No. 42371, was isolated from ginseng rotation soil. This strain possesses multiple functions, including inhibiting pathogens, degrading allelopathic substances, and promoting *Gastrodia elata* growth, achieving microbial restoration of continuous cropping obstacles. Applying this strain to the *Gastrodia elata* cultivation system not only significantly reduces the content of various allelopathic substances in the soil and improves soil physicochemical properties, but also effectively suppresses soil pests, creating a favorable soil environment for *Gastrodia elata* growth. This invention combines this strain with Sichuan pepper extract and a specific cultivation substrate to construct a comprehensive technical system that can solve continuous cropping obstacles in *Gastrodia elata*, increase yield and efficacy, and provide technical support for the sustainable development of the *Gastrodia elata* industry.

This invention discloses a medicinal and edible herbal paste made from Sichuan pepper and perilla seeds to enhance immunity, and its preparation method. It relates to the field of functional food technology and is made from the following raw materials in parts by weight: 3-8 parts Sichuan pepper extract, 12-25 parts perilla seed oil extract, 1-3 parts dried tangerine peel extract, 1-2 parts ginger extract, 8-15 parts erythritol, 10-20 parts isomaltitol, 0.1-0.3 parts xanthan gum, 40-60 parts purified water, and 0.5-1.5 parts licorice extract. This invention features innovative formulation and significant synergistic effects: Following the principles of "yin-yang balance and complementary warming and cooling" in traditional Chinese medicine, this invention scientifically combines Sichuan pepper (which warms and dispels cold) with perilla (which moistens and nourishes yin), achieving a balance of warming and moistening, dispersing and astringing, and yin-yang complementarity. The Sichuan pepper extract and perilla seed oil extract work synergistically in a weight ratio of 5:18, which not only enhances the immune-regulating effect but also avoids the pungent and drying properties of Sichuan pepper that can damage yin and the greasy nature of perilla. Studies have shown that the combination of Sichuan pepper, perilla, and ginger can synergistically improve antioxidant activity.

The invention belongs to the technical field of food additives, and provides a green-protecting agent as well as a preparation method and application thereof. The pepper extract, the sodium bicarbonate, the thyme extract and the spinach powder in a specific ratio are used as main components of the green-protecting agent, so that the green-protecting agent has a good green-protecting effect, and green vegetables can be kept in a relatively good green color for a relatively long time after being cooked; the green-keeping agent can be used for keeping green of green vegetables in stir-fried dishes, premade dishes and Chinese fast food produced in a central kitchen, can be directly used in vegetable foods, can be directly added with seasonings in the vegetable cooking process as a direct-adding green-keeping agent, and breaks through the limitation that blanching or soaking is needed in most existing color-keeping methods. All the components are food-grade natural extracts or food additives and are safe and non-toxic, so that the safety of a vegetable finished product after the green-protecting agent is used can be ensured.

The formula comprises the following components: polyhexamethylene biguanide hydrochloride, benzalkonium chloride, glycerol, propylene glycol, borneol, menthol, a folium artemisiae argyi extract, a pepper extract, an R301 miticide and the balance of water. According to the spray prepared by the invention, the herbal raw materials are used as main raw materials, and are matched with the interaction of other various components, so that the antibacterial and mite-killing performance of the spray can be greatly improved. By introducing the folium artemisiae argyi extract and the matching effect of the pepper extract extracted by a specific method, the spray can be endowed with unique herbal fragrance, meanwhile, a remarkable antibacterial effect can be achieved, most of common pathogenic bacteria including staphylococcus aureus, escherichia coli, candida albicans and the like can be effectively inhibited, and the spray has a good antibacterial effect. The pathogenic bacteria are inhibited and killed.

The invention relates to plant beverage preparation, in particular to a compound turmeric plant beverage and a preparation method thereof.The method comprises the following steps that firstly, a turmeric raw material is fed into a crushing section through a feeding section to be crushed; 2, the crushed turmeric raw material enters an extraction section to be extracted, and turmeric liquid and turmeric residues are separated; the invention relates to a compound turmeric plant beverage. The radix curcumae longae is 1,000 mg to 1,200 mg; 5 mg to 7 mg of a black pepper extract; 20 to 24 g of concentrated apple clear juice; 10 to 15 g of manuka honey; 300 mg to 340 mg of white tricholoma matsutake freeze-dried powder; 50 mg to 60 mg of vitamin C; 200 mg to 240 mg of concentrated pleurotus citrinopileatus powder; the content of glycine betaine is 500 mg to 550 mg; 100 mg to 140 mg of ground cinnamon; the volume of the water ranges from 500 mL to 550 mL. The problems of low extraction rate and system incoherence in the prior art are solved.

The invention discloses a multifunctional disposable pillow towel and a preparation method thereof, and belongs to the field of pillow towels. Comprising the following raw materials in percentage by weight: 15.4 to 25.6 percent of green prickleyash extract, 12.4 to 25.7 percent of folium artemisiae argyi, 6.1 to 13.5 percent of clove, 4.6 to 11.1 percent of lavender oil, 2.6 to 9.5 percent of pelargonium graveolens oil, 3.1 to 11.7 percent of bergamot fruit oil, 2.7 to 7.3 percent of vetiver root oil, 3.1 to 8.8 percent of sandalwood oil, 4.1 to 12.1 percent of rose oil, 3.1 to 12.5 percent of eucalyptus edulis oil and 5.1 to 14.6 percent of frankincense oil. The pillow towel is prepared from, by weight, 6.2-11.3% of manuka essential oil, 3.2-8.9% of tea polyphenol and the same amount of purified water, and the pillow towel is a disposable pillow towel. The disposable pillow towel and the preparation method thereof have the beneficial effects that the disposable pillow towel with multiple effects and the preparation method thereof are provided.

The present invention discloses an ergothioneine-curcumin synergistic anti-inflammatory and anti-aging complex composition and a preparation method thereof, relating to biomedicine and functional skincare products. A ternary nanolipid carrier core-shell structure is constructed, comprising a hydrophobic core, an interface enhancement layer, and a hydrophilic shell. The hydrophobic core formed by hydrogenated lecithin and phytosterol provides a stable lipid microenvironment for curcumin. Piperine from black pepper extract is directionally anchored at the oil-water interface region of the lipid bilayer, enabling precise interfacial localization. The hydrophilic shell composed of thiolated hyaluronic acid covalently links ergothioneine through thiol-disulfide bonds, stably fixing it on the carrier surface. This enables ergothioneine to provide immediate antioxidant protection upon contact with skin or mucous membranes while preventing migration into the lipid core, thereby achieving spatial partitioning and synergistic functionality of the three active ingredients.

The present application belongs to the field of pharmaceutical preparations, and particularly relates to a gel paste containing dry ginger and pepper extract, which contains dry ginger and pepper extract and a stabilizer, wherein the stabilizer comprises a surfactant and a humectant, and the adhesion of the gel paste is improved through specific proportioning and preparation process.

An alternative autophagy activator comprising at least one selected from the group consisting of: a coffee extract and / or a coffee residue extract; a black pepper extract; a red pine extract; a juniper berry extract; a turmeric extract; and an apple polyphenol extract.

The invention belongs to the technical field of food, and particularly relates to a nano-emulsion for improving circadian rhythm disorder sleep disorder and a preparation method of the nano-emulsion. The semen ziziphi spinosae oil emulsion comprises the following raw materials in parts by weight: 5-10 parts of semen ziziphi spinosae oil, 2-6 parts of rice bran oil, 2-6 parts of wheat germ oil, 0.43-1.15 parts of functional components, 0.78-1.15 parts of an emulsifier and 76-82 parts of water, the emulsifier comprises polyglycerol fatty acid ester, Tween 80 and propylene glycol alginate, and the functional components comprise a black pepper extract, sour cherry powder, sophora flower bud powder and balm. Natural oil and plant extracts are used as core active components, the spina date seed oil has the tranquilizing and allaying excitement effect and has a synergistic effect with unsaturated fatty acid in the rice bran oil and the wheat germ oil, and functional components such as the black pepper extract are matched to regulate neurotransmitter balance; and the problems of difficulty in falling asleep, shallow sleep and the like caused by diurnal rhythm disorder can be accurately improved.

The invention discloses a blood fat reducing composition containing supramolecular group composite peptide, which is composed of raw materials and basic energy substrates, the raw materials comprise supramolecular group composite peptide, natto freeze-dried powder, black pepper extract and bamboo leaf flavone, and the basic energy substrates comprise proteins, dietary fibers, fatty acids and / or lipids; the composite peptide is composed of soybean peptide and bitter gourd peptide. The composition prepared by compounding the components of specific types and dosages has the effects of remarkably reducing the triglyceride level, reducing the content of low-density lipoprotein cholesterol and increasing the content of high-density lipoprotein cholesterol, and part of the composition can also cooperate with statin western medicines (such as atorvastatin calcium) to achieve the effects of enhancing the effect of reducing blood fat and improving the blood fat content. The effect of assisting in improving or preventing and reducing blood fat is achieved. Therefore, the method can be used for developing functional foods and medicines and has a considerable market prospect.

The invention discloses a termite killing agent based on a peanut extract as well as a preparation method and application of the termite killing agent. The active component of the medicament is prepared by compounding 95%-98% by mass of peanut extract and 2%-5% by mass of pepper extract. The preparation method comprises the following steps: crushing dried peanuts, and extracting with an organic solvent to obtain a peanut extract; and mixing the mixture with a chili extract according to a ratio, and standing and curing for ten months under a shady and cool dark condition. The medicament disclosed by the invention has the effects of repelling, contact killing and stomach poisoning on termites by utilizing the synergistic effect of plant source active ingredients, and can realize group prevention and control through contact propagation among termite individuals. The agent is natural in components, good in environmental compatibility, rapid in degradation and safe to non-target organisms, and an environment-friendly and non-toxic solution is provided for termite prevention and control.

This invention provides a functional composition and its application, belonging to the field of functional food technology. The functional composition of this invention comprises the following components in parts by weight: 10-25 parts of Sichuan pepper extract, 5-10 parts of Gastrodia elata extract, and 2-5 parts of saffron extract; wherein the Sichuan pepper extract contains 60%-80% total flavonoids by weight, and the total flavonoids include hyperoside at 5%-15% by weight of the Sichuan pepper extract. The functional composition of this invention not only shortens sleep latency, but more importantly, it also reduces the frequency of nighttime awakenings, effectively reducing the number of nighttime awakenings at the root cause.