98 results about "Radioactive iodine" patented technology

Provided in the present invention are a preparation method for a crown ether covalent organic framework material, and the use thereof in iodine adsorption. In the present invention, an 18-crown-6-ether group is introduced into the structure of a covalent organic framework (COF) material for iodine adsorption work. The covalent organic framework material can form a one-dimensional pore channel structure in order, and the 18-crown-6-ether can be selectively complexed with iodine molecules, thereby achieving the purpose of efficient iodine adsorption. The material can perform specific iodine adsorption from high-temperature iodine steam, and the iodine steam adsorption capacity of the COF material is as high as 5.56 g / g. The COF material has a high adsorption capacity, is easy to prepare and simple to operate, has a high adsorption efficiency, and is particularly suitable for adsorbing and separating radioactive iodine in the nuclear industry.

The invention relates to the technical field of environmental protection, and discloses ionic liquid modified MOF-808 for adsorbing radioactive iodine as well as a preparation method and application of the ionic liquid modified MOF-808. The ionic liquid is loaded into pores of the MOF-808 by using an in-situ impregnation method to obtain the ionic liquid modified MOF-808 for adsorbing radioactive iodine, and the ionic liquid modified MOF-808 is expressed as X-IL (at) MOF. The MOF-808 has excellent removal performance on radioactive iodine, which is benefited from the excellent pore structure of the MOF-808 and abundant heteroatom adsorption sites of IL. After hydrophobic IL modification, the IL (at) MOF also shows good adsorption performance in a high-humidity environment.

The invention discloses a thyroid cancer lung metastasis focus iodine taking state prediction method and system based on deep learning, is used for identifying the iodine taking state of a lung metastasis focus of a thyroid cancer patient in a medical scene, and relates to the field of image processing, medical treatment and deep learning, and the method comprises the following steps: 1) obtaining lung CT image data of the patient, converting the data into a three-dimensional file, and labeling the focus of part of the patient; 2) preprocessing lung CT image data, and dividing the lung CT image data into a segmentation data set and a classification data set; (3) constructing a depth image segmentation model; (4) constructing a depth image classification model; (5) using the segmentation model to obtain the position and size of a focus of an unlabeled patient; and (6) classifying the iodine intake state of the focus obtained in the step (5) by using a classification model to obtain a classification result. According to the method, the focus iodine intake state of the thyroid cancer lung metastasis patient is identified based on deep learning, so that unnecessary radioactive iodine treatment is prevented, an effective treatment scheme is formulated, and finally the personalized treatment scheme and patient prognosis are improved.

The present invention discloses a method for adsorbing radioactive iodide ions in radioactive wastewater, which includes the following process: adding silver copper oxide to the radioactive wastewater, and the iodide ions in the radioactive wastewater react with the silver copper oxide, so that the concentration of iodide ions in the radioactive wastewater is reduced. The adsorption of radioactive iodide ions in radioactive wastewater by the silver copper oxide of the present invention belongs to chemical adsorption, which has the characteristics of fast adsorption speed, high adsorption efficiency and adsorption capacity, the adsorbed product is not easy to desorb, is easy to solidify and dispose, is convenient for recycling, is convenient to use and is not easily affected by interfering ions and pH. The silver copper oxide has a strong selective adsorption effect on iodide ions in the wastewater environment of long half-life radioactive element iodine, and can effectively improve the radioactive pollution of iodine in the water environment, and solve the main problems of spent fuel reprocessing and radioactive water pollution.

The invention discloses a preparation method and application of a melamine modified collagenous fiber iodine adsorbent, and relates to the technical field of nuclear medical radioactive waste treatment. The preparation method comprises the following steps: activating collagen fibers and modifying melamine; wherein the melamine modification comprises the following steps: taking the activated collagenous fiber, adding water, melamine and a dialdehyde cross-linking agent, and stirring at 35-45 DEG C for 6-8 hours to obtain the melamine modified collagenous fiber iodine adsorbent. According to the application, the prepared melamine modified collagenous fiber iodine adsorbent is used for adsorbing radioactive iodine. After melamine grafting, the nitrogen content of the collagenous fiber is remarkably increased, the collagen fiber has more prominent adsorption capacity on iodine steam and iodine in a solution, and an effective strategy is provided for removal and collection of radioactive iodine such as medical wastewater and radioactive waste liquid.

The invention discloses preparation of a nitrogen-rich ionic organic single crystal material and application of the nitrogen-rich ionic organic single crystal material in iodine adsorption, and belongs to the technical field of functional materials and radioactive pollutant treatment. The material is formed by self-assembly at room temperature through a solution method by taking biphenyl tetracarboxylic acid tetrabutylamine as an anion ligand and tetra (4-ethyl pyridine phenyl) ethylene bromide or tetra (4-imidazole phenyl) ethylene bromide as a cation ligand. The method is simple in preparation process, mild in condition and high in yield. The skeleton of the obtained material is rich in nitrogen sites and has a large cavity, the material shows extremely high adsorption capacity and rapid adsorption kinetics for iodine in a gas phase and a liquid phase, the maximum adsorption capacity of the material for iodine steam reaches up to 5.16 g / g, the retention rate of 95% or above can still be kept within 7 days after adsorption, and the material has good recycling performance. The material provides a novel and reliable solution for efficiently capturing and fixing radioactive iodine, and has a wide application prospect in the field of nuclear waste treatment.

The invention discloses an adsorption material for high-humidity and high-temperature iodine-containing aerosol and a preparation method thereof.According to the prepared adsorption material, polymers such as melamino-formaldehyde resin serve as a three-dimensional porous framework, and the adsorption material is prepared through a mild one-step solution processing method; an ionic polyimine network based on a lysine salt ionic liquid and carbonyl-rich polyvinylpyrrolidone are compounded on a skeleton in situ to form a porous adsorbent, and the porous adsorbent realizes efficient capture of elemental iodine (I2), methyl iodide (CH3I) and iodine aerosol through a synergistic mechanism of electrostatic induced adsorption and in-situ packaging and curing, so that the adsorption efficiency is improved, and the adsorption efficiency is improved. Under the harsh industrial conditions that the temperature is 100 DEG C or above and the relative humidity is 90% or above, the dynamic adsorption capacity to iodine reaches up to 160.7 wt%, the filtering efficiency is kept 99.8% or above, meanwhile, excellent iodine retention stability, recoverability and large-scale preparation potential are achieved, and an efficient, low-cost and practical solution is provided for treatment of radioactive iodine in nuclear waste gas.

The invention discloses a novel ionic pyridyl covalent organic framework material and application thereof in iodine adsorption. According to the invention, an ionic pyridyl group is introduced into the structure of the covalent organic framework material, and the covalent organic framework material is applied to iodine adsorption. The I-coated COF-DMPD-1 can induce iodine molecules to form polyiodide anions through iodide ions, and meanwhile, electrostatic interaction is formed between the formed polyiodide anions and a cation skeleton, so that the I-coated COF-DMPD-1 has high adsorption performance on iodine. The I (at) COF-DMPD-1 has a high adsorption rate on iodine in high-temperature iodine vapor, and the adsorption capacity of the I (at) COF-DMPD-1 on iodine is as high as 8.92 g / g. The I-coated COF-DMPD-1 has the advantages of high adsorption capacity, high adsorption rate and cyclic adsorption, and is suitable for adsorbing and separating radioactive iodine in the fields of nuclear industry and environmental pollution.

The invention belongs to the technical field of radioactive waste treatment, and discloses a ceramic solidified body for synergistically solidifying radioactive iodine and cesium as well as a preparation method and application of the ceramic solidified body. The chemical formula of the ceramic solidified body is (Cs2xBa2-2x) (AgyNa1-y) IO6, x is equal to 0.1-0.9, y is equal to 0.1-0.9, and the ceramic solidified body is prepared by mixing silver iodide, barium hydroxide, sodium periodate and cesium carbonate, carrying out dry pressing molding under 20-60 MPa to obtain a rough blank, sintering at 500-700 DEG C, carrying out cold sintering at 200-300 DEG C, and finally annealing at 500-600 DEG C. The curing amount of iodine in the ceramic cured body is 2.4-20 wt%, the curing amount of cesium is 4-46 wt%, and the ceramic cured body has excellent chemical stability and is suitable for curing radioactive iodine and cesium and long-term geological treatment.

The invention discloses a multifunctional medical iodine instrument, which comprises an anti-radiation shell unit which is used for wrapping the outer side of the iodine instrument and wrapping and protecting inner side parts of the iodine instrument; the control module adopts a modular structural design; the needle inserting module is used for carrying out automatic needle inserting on a liquid medicine bottle placed in the iodine taking instrument; the use method of the multifunctional medical iodine taking instrument comprises the following steps: S1, liquid medicine preparation: moving down a needle inserting module, inserting a needle into a stock solution bottle, conveying the liquid medicine in the stock solution bottle into an activity meter bottle, and measuring the activity a1 of the stock solution at the moment; s2, specific activity calibration: pumping 1ml of the liquid medicine from the transfer bottle to an activity meter bottle, measuring the specific activity A1 of the liquid medicine at the moment, taking the specific activity A1 as a background, pumping 1ml of the liquid medicine from the transfer bottle, and measuring the specific activity A2 of the liquid medicine in the activity meter bottle at the moment. Accurate activity control and environment dynamic compensation are realized, and excellent clinical application value and technical advantages are shown in the radioactive iodine treatment process.

The invention discloses a CPN-Y2-Cl cation framework material as well as a preparation method and application thereof. The CPN-Y2-Cl cation framework material is constructed by carrying out quaternization reaction on tetra (1-imidazole phenyl) ethylene and 5, 5 '-bromomethyl-2, 2'-dipyridyl, and is obtained by carrying out anion exchange. The material has rapid and efficient adsorption performance on I3 <-> in a water phase, and still shows good selectivity in the presence of various competitive anions. Meanwhile, the material has obvious fluorescence quenching in the process of acting with I3 <->, and rapid detection of I3 <-> in water can be realized. The material designed by the invention is stable in performance, the preparation process is simple and convenient, and the prepared organic cation framework material has dual functions of adsorption and fluorescence recognition, and has a wide application prospect in the fields of treatment and real-time monitoring of radioactive iodine polluted water.

The present invention discloses a hydrogen-bonded aromatic amide molecular cage compound, a preparation method thereof and an application thereof, belonging to the technical field of porous organic functional materials. In the present invention, an imine intermediate is synthesized by a dynamic covalent chemical imine condensation reaction of a hydrogen-bonded oligomeric aromatic amide diamine monomer and a trialdehyde monomer in dichloromethane, and then in-situ one-pot reduction is carried out using NaBH3CN to finally obtain an aromatic amide cage molecule. The preparation method is simple, and the reaction monomers are cheap and easily available. At the same time, the hydrogen-bonded aromatic amide molecular cage compound prepared in the present invention has high thermal stability and high chemical stability, and can efficiently adsorb iodine in solution state and gas phase (including I2, I3 ‑ and CH3I), and can be applied to the design and development of high-performance radioactive iodine capture materials.

The invention belongs to the field of nuclear industry protection, and discloses a radioactive iodine filter cartridge protection time evaluation method, which comprises the following steps: collecting data by using a protection time test device; the collected data is subjected to multivariate nonlinear regression fitting, a radioiodine filter cartridge protection time model is obtained, and the fitting model is as follows: x1 is a main factor influencing the protection time of the radioiodine filter cartridge in the working environment humidity, the working intensity and the radioiodine activity concentration; x2 and x3 are the other two secondary factors respectively; and substituting the working condition into the radioactive iodine filter cartridge protection time model to obtain the protection time of the radioactive iodine filter cartridge under the working condition. The method provided by the invention can promote the resource conservation of the radioactive iodine filter cartridge and reduce the cost of subsequent radioactive waste disposal.

The invention discloses a preparation method of a stannous sulfide-mesoporous silica material for adsorbing radioactive iodine, which comprises the following steps: dissolving stannous chloride dehydrate, thiourea and PEG (polyethylene glycol) 1500 in a mixed solution of absolute ethyl alcohol and ethylene glycol, then adding mesoporous silica, heating and stirring to obtain a mixed solution; transferring the obtained mixed solution into a hydrothermal reaction kettle, carrying out hydrothermal reaction, then naturally cooling to room temperature, and washing to obtain the stannous sulfide-mesoporous silica material adsorbing radioactive iodine. The invention develops a novel efficient radioactive iodine adsorption material which has the advantages of low cost, high iodine adsorption capacity, easiness in macro preparation and the like, and a new material and a new method are provided for radioactive gaseous iodine treatment.

A synthesis method of active antimony sulfide for gaseous radioactive iodine adsorption comprises the following steps: S1, mixing inorganic compound powder A, macrocyclic polyamine B and sulfur powder, putting the mixture into a container, and adding deionized water to obtain a mixture; s2, carrying out ultrasonic treatment on the mixture treated in the step S1, putting the mixture into a drying oven, and reacting for a certain time; and S3, after the reaction is finished, cooling to room temperature, filtering a product, and respectively washing with deionized water, a reagent G and a reagent F to obtain the three-dimensional framework active inorganic antimony sulfide. Through solvothermal reaction, the organic amine structure guiding effect is combined with ultrasonic vibration, the accumulation mode of the anion layer is directly influenced, then layered or open-frame crystals are formed, finally, a three-dimensional metal frame structure is formed, and the iodine adsorption saturation capacity is high.

The invention relates to the technical field of nuclear medical radioactive waste treatment, and discloses a preparation method and application of a triazine modified collagenous fiber iodine adsorbent. The preparation method comprises the following steps: activating collagen fibers; and triazine modification: taking the activated collagenous fiber, adding water, triazine and a dialdehyde cross-linking agent, and stirring at 25-50 DEG C for 5-10 hours to obtain the triazine modified collagenous fiber iodine adsorbent. According to the application, the prepared triazine modified collagenous fiber iodine adsorbent is used for adsorbing radioactive iodine. According to the preparation method disclosed by the invention, triazine is grafted to the activated collagenous fiber through the Schiff base reaction of the dialdehyde cross-linking agent, and the collagenous fiber is endowed with a large number of N hybrid functional groups, so that the active sites of the obtained modified collagenous fiber adsorbent are remarkably increased, and iodine ions in iodine steam and a solution can be effectively adsorbed; the adsorbent can be used for adsorbing radioactive iodine in medical waste liquid and nuclear wastewater, the preparation method is simple, raw materials are wide in source and low in price, and industrialization can be achieved.

The present invention discloses a bismuth-based bimetallic aerogel adsorbent and a preparation method and application thereof, including: forming a bismuth-based bimetallic aerogel adsorbent having a three-dimensional mesh porous structure by co-solution of bismuth and transition metal; the transition metal is one of nickel, palladium and silver. The present invention constructs a bismuth-based bimetallic aerogel material having a three-dimensional porous structure, and on the premise of maintaining the high adsorption performance of the bismuth-based material for radioactive iodine, synergistically utilizes the physical adsorption enrichment effect of the three-dimensional porous structure of the aerogel, and improves the thermal stability of the bismuth aerogel, so that the bismuth-based bimetallic aerogel adsorbent has excellent selectivity and efficient removal ability for gaseous radioactive iodine ions; at the same time, the preparation process of the present invention is simple and efficient.

The invention discloses a radiopharmaceutical waste curing treatment method which comprises the following steps: mixing expanded perlite and alumina powder, putting the mixture into a high-temperature furnace for heating, and carrying out high-temperature melting expansion to form closed-pore spherical vitrified micro-beads; the preparation method comprises the following steps: stirring and mixing closed-pore spherical glass beads, silica fume, nano-silica and an epoxy resin curing agent, and then adding a methylcellulose plasticizer and cerium oxide to form a base material; adding the pre-dried radiopharmaceutical waste into the base material, and uniformly stirring to form a mixture; injecting the mixture into a mold for molding and primary curing, and performing steam curing and environment curing after demolding to obtain a cured body; according to the present invention, the expanded perlite and the alumina powder are subjected to high temperature melting to prepare the closed-pore spherical vitrified micro-bead, the physical adsorption capacity of the porous structure of the closed-pore spherical vitrified micro-bead on the radioactive iodide ion is utilized, and the stable iodide generated by the aluminum element is combined to achieve the chemical bonding so as to reduce the iodine-131 escape problem in the high temperature environment;

The utility model discloses a movable radioactive iodine continuous monitor and detection device, and belongs to the technical field of nuclear facilities and air detection. According to the movable radioactive iodine continuous monitor, the reliability and the accuracy of detection data are improved by arranging the detection device, the detector can conveniently monitor at different places by designing the main wheels, and the working efficiency is improved. According to the detection device, the size of the iodine box is set to be consistent with the size of the probe of the NaI detector, so that the NaI detector can monitor radioactive iodine in air more comprehensively, the reliability of a monitoring result is improved, and resource waste caused by the fact that the arranged probe is too large is avoided. By using the lead chamber, external interference is effectively shielded, and the accuracy of monitoring data is improved. And more accurate radioactive activity concentration data can be provided through a multichannel analyzer. The problem that the monitoring result of an existing monitor is unreliable due to the defect of incomplete monitoring is solved.

It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphosphocholine analogs are compounds having the formula:or salts thereof, wherein n is an integer from 12 to 24; and R2 is —N+(CH3)3. The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, R1 includes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection / imaging applications, R1 includes a detection moiety, such as a fluorophore or a radioactive iodine isotope.

The invention belongs to the technical field of biological medicines, and particularly relates to a drug-loaded vesicle for treating thyroid cancer as well as a preparation method and application of the drug-loaded vesicle. The drug-loaded vesicle comprises a vesicle, wherein a cavity of the vesicle is loaded with radioactive iodine; the membrane surface of the vesicle is modified with: a) a first single-chain antibody fragment capable of specifically binding to thyroglobulin; according to the present invention, after the intravenous injection, the drug-loaded vesicle can be enriched in the thyroid cancer lesion area of the RAIR-DTC patient, such that the cancer cell proliferation is inhibited while the radioactive iodine is continuously released so as to provide the long-term treatment effect;

The invention relates to an adsorption material, a forming method and application of the adsorption material in radioactive iodine purification. Wherein the adsorption material comprises polymer porous particles and an active powder adsorption material embedded in the inner walls of pore channels of the polymer porous particles; the polymer porous particles are formed by a phase inversion method. The invention mainly provides the adsorption material, on the basis that the polymer porous particles are used as a framework, and the active powder adsorption material is embedded in the surfaces of the pore channels of the polymer porous particles, on the one hand, the problem that the adsorption pressure drop is too large when the particles of the active powder adsorption material are directly stacked for adsorption operation is avoided, and the adsorption pressure drop is reduced; on the second aspect, the active powder adsorption material in the stack can be in rapid contact with an adsorbed medium, and the adsorption effect is improved; and on the third aspect, the damage to an adsorption powder structure when a powder extrusion forming process is adopted is avoided, and the stacking degree between powder materials is reduced.

Disclosed are a developable embolic bead capable of loading radioactive iodine and a negatively charged drug, a preparation method therefor, and a use thereof. The bead is a quaternary ammonium salt bead containing a catechol structure and elemental iodine, and can be loaded with radioactive iodine and a negatively charged drug. In the present invention, a quaternary ammonium salt bead containing a catechol structure is prepared, using a polyamine polymer or a hydrochloride thereof, a catechol monomer, and an iodine-containing monomer as primary raw materials; the bead can be loaded with radioactive iodine and a negatively charged drug, thereby achieving combined radiotherapy, chemotherapy, and embolization treatment, as well as development diagnosis, of tumors.

The application discloses a thiol-functionalized metal organic framework material and a preparation method and application thereof, and aims at the urgent demand of efficient adsorption of radioactive iodine, combines supergravity synthesis technology with a post-synthesis modification strategy, and successfully prepares the thiol-functionalized metal organic framework material IRMOF-3-SH.The research of the application proves that the supergravity method can quickly synthesize the MOF material with regular crystal form and uniform particle size by strengthening the mass transfer and nucleation process, and further obtains the thiol-functionalized IRMOF-3-SH through the supergravity post-synthesis modification method, so that the iodine adsorption capacity is significantly improved to 3.00 g·g ‑1 , which is increased by 46% compared with the unmodified material, and the excellent cycle stability is exhibited.

The invention relates to the field of medical health, and provides a personalized low-iodine diet control system and control method based on artificial intelligence, a data management module collects patient basic information, an iodine content database, patient diet record data and patient examination data; the personalized low-iodine recommendation module generates a personalized low-iodine menu through a low-iodine diet algorithm according to the collected data, generates patient guidance suggestions and issues the patient guidance suggestions to the patient side; and the risk assessment and early warning module estimates the daily iodine intake of the patient according to the diet record data of the patient and the examination data of the patient, and performs risk assessment and early warning on the daily iodine intake of the patient in combination with the target daily iodine intake. According to the invention, personalized low-iodine diet control based on a food iodine content table, diet records and an intelligent algorithm can be realized for a patient subjected to radioiodine 131 treatment after a thyroid cancer total resection operation.

The invention discloses a method and system for estimating the concentration of radioactive iodine species in a containment after an accident, and the method comprises the steps: inputting the content of gaseous iodine in the atmosphere of the containment, and calculating the acid content in the wall surface of the containment and the liquid phase of a pit; on the basis of the content of acid in the pit liquid phase and the content of a medicine added into the pit in advance, the pH value in the pit liquid phase is calculated through a pH model; determining the content of iodine which enters the liquid phase of the pit and does not participate in the chemical reaction of the liquid phase; on the basis of the content and the pH value of iodine which can be subjected to chemical reaction in the pool, combining an iodine water chemical equation, and calculating through a liquid phase chemical reaction model to obtain the concentrations of different iodine species in a liquid phase; calculating the mass transfer amount of gaseous iodine in the gas phase between the containment atmosphere and the pit water based on a pool mass transfer model; the content of gaseous iodine in the containment atmosphere is calculated through a gaseous iodine radiolysis and ionization model; determining the content of iodine deposited on the dry wall surface of the containment based on a gaseous iodine deposition model; and finally outputting the concentration of each iodine species in the gas liquid.

The application discloses a kind of preparation and application of multi-level hole full-silica zeolite limited copper-bismuth Janus nanoparticle adsorbent, comprising: copper salt and bismuth salt are dissolved in dilute nitric acid solution and then added into deionized water, to obtain bimetallic salt solution;Metal salt solution is added to the raw material for synthesizing full-silica zeolite to pre-crystallize, to obtain gelatinous solution;The obtained gelatinous solution is moved into reaction kettle to carry out hydrothermal crystallization;The obtained sample is filtered, washed, dried, and calcined under inert gas protection, to obtain multi-level hole full-silica zeolite limited copper-bismuth Janus nanoparticle adsorbent.The adsorbent prepared in the application has a multi-level hole structure of microporous-mesoporous, which can avoid oxidation and loss of metal particles during the adsorption process, and the adsorbent is applied to remove radioactive iodine gas, showing high iodine adsorption capacity, and reacting with iodine molecules to form thermodynamically stable CuI and BiI3, further improving the iodine solidification capacity of the adsorbent.

It is disclosed herein that that certain alkylphosphocholine analogs are preferentially taken up by malignant pediatric tumor cells. The alkylphophocholine analogs are compounds having the formula:or salts thereof, wherein n is an integer from 12 to 24; and R2 is —N+(CH3)3. The compounds can be used to treat pediatric solid tumors or to detect pediatric solid tumors. In therapeutic treatment, R1 includes a radioactive iodine isotope that locally delivers therapeutic dosages of radiation to the malignant pediatric tumor cells that preferentially take up the compound. In detection / imaging applications, R1 includes a detection moiety, such as a fluorophore or a radioactive iodine isotope.

The invention relates to an iodine-131 labeled FAPI-TFMP-Y4 targeting molecular probe as well as a preparation method and application of the iodine-131 labeled FAPI-TFMP-Y4 targeting molecular probe. The probe combines the tumor targeting property of FAPI-46 and the characteristics that TFMP-Y4 small molecule polypeptide is safe and can stably stay in tumor cells for a long time, the novel molecular probe can obviously increase the uptake of the tumor cells and effectively prolong the residence time in the tumor cells, and the treatment effect on pancreatic cancer, non-small cell lung cancer and other tumors is improved. The invention also provides a preparation method of the probe. The preparation method comprises the following steps: synthesizing an ATE-FAPI-TFMP-Y4 precursor and carrying out radioiodine labeling. Experimental results show that the probe shows good tumor targeting, stability and anti-tumor activity in vitro and in vivo, and has low toxic and side effects on normal cells. The invention provides a new thought and method for treating pancreatic cancer and non-small cell lung cancer.

The present invention belongs to the technical field of tumor treatment drug research, and specifically relates to an iodine-125 labeled iron-based nanomaterial and its use. The iron-based nanomaterial is obtained by labeling a metal-organic framework material of iron with a radionuclide 125 I. When in use, the iron-based nanomaterial provided by the present invention can continuously generate hydrated electrons (e aq ‑ ) for a long time by using radioactive iodine 125. e aq ‑ promotes the conversion of transition metals from high valence states to low valence states, improves the Fenton reaction efficiency at the tumor site, and the anti-tumor efficacy of chemodynamic therapy.