36 results about "Nasolacrimal duct" patented technology

The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct that comprise a body, at least one cap, and optionally a collarette.

A nasolacrimal stent device illuminates a dark nasal cavity so that the interior of the nasal cavity can be directly observed to facilitate and ensure the correct insertion of a nasolacrimal stent into the nasal duct. Flexible, transparent probe tube segments (21) are connected to the opposite ends of a flexible detention tube segment (2) having a diameter that permits the flexible detention tube segment (2) to be inserted in a lacrimal passage, respectively. The respective extremities of distal end parts (21a, 21b) of the probe tube segments (21) are closed. The probe tube segments (21) are provided in their base end parts with openings (23), respectively. When inserting each probe tube segment (21) into the nasal cavity, an illuminating device, such as an optical fiber (30) is inserted through the opening (23) into the probe tube segment (21) to illuminate the interior of the nasal cavity through the transparent probe tube segment (21). The probe tube segment (21) can be surely caught with a hook and can be pulled out from the nasal cavity. An ultrasonic probe or an endoscope may be used instead of the illuminating device to find the position of the nasolacrimal stent in the nasal cavity.

The invention discloses a degradable medical composite conduit containing a functional nano coating and a preparation method thereof, which is characterized in that the composite conduit is in a three-layer structure, wherein an inner layer and a middle layer are formed through the melt extrusion compounding by a medical-conduit precision extruder, an outer layer is formed by spraying a degradable high-molecular material dissolved with an effective quantity of active medicaments to the outside of a double-layer composite pipe, and the thickness of the outer layer does not exceed 300nm. The conduit not only overcomes the deficiencies of a metal medical conduit, but also well controls the medicament releasing speed and the conduit degrading speed through a composite structure, is mainly applied to the interventional therapies of trachea, bronchus, esophagus, alimentary canals, bile ducts, nasolacrimal ducts and the like and has broad application prospect.

The invention discloses hydrogel. The hydrogel comprises the following preparation raw materials in parts by weight: 10 to 80 parts of hydroxyethyl methylacrylate, 1 to 20 parts of a crosslinking agent, 10 to 80 parts of water and 0.042 to 36 parts of a reaction releaser, wherein the crosslinking agent is at least one of polyethylene glycol diacrylate, ethylene glycol dimethacrylate and isocyanuric acid triallyl ester; and the reaction releaser is a mixture of a thermal initiator and a catalyst or a photoinitiator. The hydrogel has high hydrophilic performance, has high mechanical property andhas high biocompatibility and stability in a human body. The invention also provides an artificial nasolacrimal duct containing the hydrogel. The artificial nasolacrimal duct has high tear guide efficiency, high biocompatibility and stability, can obtain longer implanting cycle and is not liable to cause rejection and inflammatory response after long-term implantation; and the artificial nasolacrimal duct can be expanded by absorbing water and can achieve the self-fixing effect; and the implanting mode is simple and easy to operate.

The invention discloses an artificial nasolacrimal duct. The artificial nasolacrimal duct comprises the following preparation raw materials in parts by weight: 10 to 80 parts of hydroxyethyl methylacrylate, 1 to 20 parts of a crosslinking agent, 10 to 80 parts of water and 0.042 to 36 parts of a reaction initiator, wherein the crosslinking agent is at least one of polyethylene glycol diacrylate, ethylene glycol dimethacrylate and triallyl isocyanurate; the reaction initiator is a mixture of a thermal initiator and a catalyst or a photoinitiator. The invention further provides a preparation method of the artificial nasolacrimal duct. The artificial nasolacrimal duct has relatively high tear guide efficiency, high biocompatibility and high stability, can obtain longer implantation cycle, andis not liable to cause rejection or inflammatory reaction during long-time implantation; the artificial nasolacrimal duct can be expanded when absorbing water, and achieves a self-fixing effect; theimplantation mode is simple and the operation is facilitated.

The invention relates to animal feed, particularly a dry type food used for aged pet dogs. The food comprises following components by mass: 1-2% of a black sesame extract product, 2-3% of an oat extract product, 1-2% of a barbary wolfberry fruit extract product, 0.5-1% of a honeysuckle bud and flower extract product, 0.5-1% of a wild chrysanthemum flower extract product, 5-10% of egg white powder, 1-3% of bovine bone powder, 2-5% of pig liver, 1-3% of threonine, 1-6% of calcium lactate, 0.5-1.5% of lysine, 40-60% of meat, 2-5% of vegetables, 1-6% of potassium sorbate, 1-3% of deep-sea fish oil, 0.5-1.5% of animal oil, 0.5-1.5% of a carrot extract product, 3-6% of gelatin, 0.5-0.8% of toosendanin, 1-2% of insect proteins, 1-5% of vitamin C and 1-3% of a food additive, with the balance being corn flour. The food is capable of preventing gastric distention, reducing the occurrence rate of cardiovascular disease, improving baldness, reducing lacrimal gland and nasolacrimal duct abnormity, lowering blood pressure and preventing thrombosis.

The invention provides a biological retina, which is applied to tissue repair in the field of ophthalmological department. The tissue repair includes glaucoma trabeculectomy, a neovascular glaucoma surgery, uveitic glaucoma, a pterygium surgery, a strabismus surgery, a nasolacrimal duct operation, an orbital surgery, an ocular plastic surgery, a conjunctival scar tissue reconstruction surgery, a burn repair surgery and a corneal ulcer surgery; and the preparation method comprises the following steps: preparing a high-purity type I collagen and glacial acetic acid water solution according to a preset proportion and emulsifying; and vacuumizing the emulsified slurry and freeze-drying the slurry so as to obtain a collagen film having a three-dimensional porous structure. The biological retina disclosed by the invention has beneficial effects that the prepared biological retina, which takes the collagen, as a major ingredient, is good in biocompatibility and biodegradability and is capable of controlling an inflammatory reaction; the high-purity collagen is free from antigenicity and repellency; by virtue of the three-dimensional porous structure, the random and discrete hyperplasia of fibroblasts is guided; and the biological retina can inhibit conjunctival scars and conjunctival contraction, and can keep normal intraocular pressure.

Relating to the technical field of pet products, the invention discloses a pet tear stain removal composition, a pet tear stain removal product and a preparation method thereof. The pet tear stain removal composition comprises a marigold extract, a green tea extract, a Chinese wolfberry extract, a cranberry extract, a grape seed extract and a euphrasia pectinata extract. The pet tear stain removalproduct comprises the pet tear stain removal composition and an auxiliary material. Through compatibility of the antioxidant substances of the marigold extract, the green tea extract, the Chinese wolfberry extract, the cranberry extract, the grape seed extract and the euphrasia pectinata extract, the pet tear stain removal composition provided by the invention has bacteriostatic properties, can effectively alleviate the pet eye stress, inhibit inflammation, dredge nasolacrimal ducts, mitigate the symptoms of pet tear stains fundamentally, and improve the beauty of pets.

The invention discloses an artificial nasolacrimal duct capable of achieving self-expanding fixation. The artificial nasolacrimal duct is of a hollow tubular structure. The inner diameter of the hollow tubular structure is 0.5-1.5 mm, and the outer diameter of the hollow tubular structure is 0.6-4.0 mm: the artificial nasolacrimal duct is made of water absorbent and expansible materials. The artificial nasolacrimal duct is simple in structure, and does not need to be set into a structure with the end size larger than the physiological size of the lacrimal passage so as to achieve the purpose of fixation, the fixation effect is good, and the duct is not easy to fall off after absorbing water and expanding.

The invention discloses a nasolacrimal duct bracket for wing-shaped fixed parts, which comprises a drainage tube and at least two wing-shaped fixed parts, wherein one end of the wing-shaped fixed part is fixed at the head end of the drainage tube, while the other end extends radically and obliquely. The nasolacrimal duct bracket for the wing-shaped fixed parts has the advantages that the bracket is convenient to collect tears and drain, can maintain smooth movement of the nasolacrimal duct, has simple manufacture, and so on.

The invention discloses hydrogel. The hydrogel is prepared from the following preparation raw materials in parts by weight: 10 to 80 parts of hydroxyethyl methacrylate, 1 to 40 parts of glycerol, 1 to20 parts of a crosslinking agent, 10 to 40 parts of water and 0.013 to 36 parts of an initiator, wherein the crosslinking agent is at least one of polyethylene glycol diacrylate, ethylene glycol dimethacrylate and triallyl isocyanurate. The hydrogel disclosed by the invention has good hydrophilic performance and relatively strong mechanical properties, and has relatively good biocompatibility andstability in human bodies. The invention further provides an artificial nasolacrimal duct containing the hydrogel disclosed by the invention. The artificial nasolacrimal duct prepared from the hydrogel disclosed by the invention has relatively high tear guiding efficiency and relatively good biocompatibility and stability; a longer implanting period can be obtained and rejection and inflammatoryresponses are not easily caused after the artificial nasolacrimal duct is implanted for a long period; the artificial nasolacrimal duct can be expanded after absorbing water and a self-fixing effect can be realized; an implanting manner is simple and easy to operate.

The invention provides a lacrimal passage drainage tube pull-out device which comprises a conveying tube, a traction tube and a balloon arranged at one end of the traction tube, wherein the traction tube comprises a connecting section and an elastic injection section, the balloon and the elastic injection section are arranged at the two opposite ends of the connecting section, and the caliber of the elastic injection section is gradually decreased in the direction away from the balloon; during use, the elastic injection section extends into the conveying tube; part of the conveying tube extends into the nasolacrimal duct of a human body and reaches a drainage tube, the traction tube is pushed to extend out of the nasal cavity, the conveying tube is withdrawn from the nasolacrimal duct of the human body, and a gas or liquid is injected into the balloon through the elastic injection section, so that the balloon is expanded to pull the traction tube, and the drainage tube is pulled out under the driving of the balloon. The lacrimal passage drainage tube pulling-out device is simple and convenient to use, and the technical problem that no corresponding lacrimal passage drainage tube taking-out device exists on the market to take out the lacrimal passage drainage tube is solved.

A bicanalicular probe intended to be inserted into the nasolacrimal duct of a patient including a central tubular part 1 made from a material compatible with insertion into the human body, preferably silicone, and two termination parts 4, 5 each fixed to one end of the central tubular part 1, characterized in that the two thickened parts 6, 7 project from the central tubular part, the two thickened parts being firstly at a distance from each other and secondly each at a distance from the ends 2, 3 where the termination parts are attached.

The invention provides compound nano eye drops and a preparation method thereof, and belongs to the technical field of eye drops. The compound nano eye drops provided by the invention simultaneously contain two medicines, namely the plinzolamide and the brimonidine tartrate, and the adhesive, the stabilizer and the osmotic pressure regulator are used in a matched manner, so that the complexity and the medication frequency of combined medication can be reduced; the particle size of solid particles in the eye drops is nanoscale, the specific surface area of the medicine is large, the residence time of the medicine in front of the cornea can improve the irritation effect of the large-particle medicine on eyes, and the compliance of a patient is improved. The adhesive increases the specific surface area of the brinzolamide medicine, increases the residence time of the hydrophobic medicine in front of cornea, reduces the loss of the medicine in eyes, reduces systemic side effects caused by loss through nasolacrimal ducts, improves the bioavailability, prolongs the medication cycle of the eye drops through slow release, and improves the antibacterial and anti-inflammatory effects; no preservative is contained, so that secondary injury to eyes of a patient is avoided.

The invention relates to an assembling type lacrimal passage expansion support. The lacrimal passage support comprises a thin-wall hollow foldable hose, a memory titanium guide wire, a wax impregnated2-0 suture, a water control holder and a flat-end injection needle; the wax impregnated 2-0 suture is tied to the middle section of the thin-wall hollow foldable hose in a slipknot mode; the flat-endinjection needle is cooperatively used at one end of the thin-wall hollow foldable hose; the memory titanium guide wire penetrates through the thin-wall hollow foldable hose. The support has the advantages that according to the sizes of lacrimal sacs and lacrimal passages, memory titanium guide wires with different elasticities are individually selected to be combined with the thin-wall hollow foldable hose; by means of resilience of the guide wire, the support is stabilized, and falling off is prevented; meanwhile, by cooperating with the water control holder on the head of a silicone hose and making the hose filled with water through the flat-end injection needle, the functions of expanding the lacrimal passages, improving blockage, moving nasolacrimal ducts and exercising lacrimal passage sphincter muscles are achieved.

The present invention relates to a nasolacrimal duct tube. A nasolacrimal duct tube, according to one embodiment of the present invention, comprises a lachrymal passage enabling lachrymal fluid to move between the inside and outside of the tube. According to the present invention, since lachrymal fluid can easily be discharged even while the tube is inserted into a human body, it is possible to decrease the possibility of inflammation occurring and the risk of infection, and it is possible to permanently leave the tube in the body without removing the tube after the operation.