56 results about "Anterior cornea" patented technology

Described herein are designs and design methods for intracorneal inlays with intrinsic dioper power (i.e., index of refraction different from the surrounding cornea tissue). The designs and design methods achieve a desired refractive change by a combination of the intrinsic diopter power of the inlay and the physical shape of the inlay, which alters the shape of the anterior cornea surface.

Ophthalmic conditions such as presbyopia, myopia, and astigmatism can be corrected by the use of a molding contact lens in combination with a pharmaceutical composition suitable for delivery to the eye. The molding contact lenses are preferably commercially available and are not specifically designed for orthokeratology. The agents in the pharmaceutical compositions such as hyaluronase allow the cornea of the eye to be molded in order to correct the refractive error of the eye. The contact lenses and the pharmaceutical composition induce a change in the radius of curvature of the anterior surface of the cornea, thereby correcting the refractive error of the eye. One advantage of the inventive technique is that the patient with his or her own individual visual needs guides the treatment until the patient near and far visual needs are met. The present invention also provides for kits, which contain molding contact lenses, pharmaceutical composition suitable for delivery to the eye, and instructions, useful in the inventive system.

A method of selecting a toric lens by taking into consideration the magnitude and orientation of the posterior cornea and/or the location of the incision axis is described. The magnitude and orientation of the posterior cornea can be calculated as a function of the measured pre-operative orientation of the steep meridian of the anterior cornea.

The invention discloses a sclera mirror. The mirror comprises a mirror body, wherein an optical area, a transition area and a positioning area are continuously formed on the lens body from the centerto the outside, the joint of a cornea and the sclera is sequentially divided into a cornea part, a transition part and a sclera part in the direction from the cornea to the sclera, the positioning area is attached to the sclera and used for positioning the sclera mirror, the transition area stretches across upper parts of the cornea and the sclera, an optical area is arranged at a front end of thecornea and provides vision correction for eyes, the transition area is arranged to be of any one of a one-section arc structure or a two-section arc structure or a three-section arc structure according to different shapes of the cornea part, the transition part and the sclera part, distinguishing design can be conducted according to different shapes of the cornea part, the transition part and thesclera part, and the wearing comfort is improved.

The invention relates to a corneal shaping lens. The corneal shaping lens comprises an inner surface facing the human cornea during wearing and an outer surface opposite to the inner surface, whereinthe inner surface comprises a base curve area located in the center, the base curve area is used for pressing the front surface of the cornea and shaping the front surface of the cornea to be consistent with the base curve area and comprises two or more areas, and the at least two of the areas have different curvature radii.

A keratoprosthesis and system and method of using same for corneal repair. The keratoprosthesis comprises a biocompatible support and an optic member disposed through a channel within the support. The support includes metal, preferably titanium, and treated, such as by sandblasting and/or acid etching, to create textured surfaces that promote soft tissue adhesion. A locking member interconnects the optic member and support. An outer surface of the locking member a collar extending from the support and disposed around the optic member is also metal, preferably titanium, and is similarly treated to promote soft tissue adhesion. A locking member interconnects the optic member and support. The system includes the keratoprosthesis positioned within an isolated soft tissue segment of a non-ocular tissue, such as buccal mucosa, placed on the anterior cornea. The method includes removing corneal epithelium, isolating and transplanting a segment of soft tissue to the de-epithelialized cornea, creating a receiving area in the soft tissue, positioning a keratoprosthesis relative to the receiving area anterior to the cornea, and securing the keratoprosthesis.

The invention relates to a keratectasia measurement method based on optical CT. The keratectasia measurement method comprises the following steps: 1, acquiring a full-cornea three-dimensional cross section image through optical CT at a long scanning depth; step 2, adopting the shortest path and a dynamic programming optimization algorithm to automatically extract the height information of front and rear surfaces of the full cornea and rebuilding a three-dimensional full-cornea height information graph based on image feature information; step 3, building two indexes representing cornea surface irregularity, namley surface extension rate (as shown in the specification) and cornea surface curvature square (as shown in the specification) based on the height information of the front and rear surfaces of the full cornea. According to the invention, the full-cornea three-dimensional cross section image is acquired through optical CT at the long scanning depth, and the two indexes representing cornea surface irregularity, namely the surface extension rate (as shown in the specification) and the cornea surface curvature square (as shown in the specification) are built.

The invention provides a method for detecting intraocular astigmatism and astigmatism axis, which comprises the following steps: 1, obtaining ocular diopter by using retinoscopy optometry or computeroptometry, converting the ocular diopter from a glasses plane to a cornea plane, and obtaining ocular total astigmatism according to the diopter of the cornea plane; 2, indirectly obtaining corneal anterior surface astigmatism by using a corneal curvature meter; and 3, detecting intraocular astigmatism by utilizing a vector relationship among total ocular astigmatism, intraocular astigmatism and corneal anterior surface astigmatism. According to the method, the intraocular astigmatism degree and the astigmatism axis can be accurately obtained no matter how the relation between intraocular total astigmatism and corneal anterior surface astigmatism is by adopting existing simple equipment and simple and convenient optometry means such as retinoscopy optometry or a computer optometry instrument and a corneal curvature meter. The method is simple, convenient to operate and high in accuracy.

The invention discloses a diopter calculation method for a toric intraocular lens. The method comprises the following steps of: calculating the change of the tangential curvature of the front surfaceof a cornea through SIA provided by a doctor after a corneal incision is made, and obtaining the tangential curvatures of a flat axis and a steep axis of the front surface of the cornea; calculating curvature radiuses of flat axis and the steep axis of the front surface of the cornea according to the tangential curvature of the flat axis and the steep axis of the front surface of the cornea, and calculating curvature radiuses of the flat axis and the steep axis of the rear surface of the cornea according to the tangential curvatures of the flat axis and the steep axis of the rear surface of the cornea; further calculating the focal length of the incident light and the output light on the anterior surface of the flat and steep axes, the focal length of the incident light and the output light on the posterior surface and the focal length of the incident light on the intraocular lens according to the radius of curvature, corneal thickness, anterior chamber depth, ocular axis length, intraocular lens parameters and reserved diopter of the anterior and posterior surfaces of the flat and steep axes, and then calculating the diopter of the required IOL flat axis and steep axis.

In certain embodiments, an ophthalmic system for determining the topography of the anterior surface of the cornea of an eye comprises an illuminator, a camera, and a computer. The illuminator illuminates the anterior surface of the cornea of the eye with a Placido pattern. The Placido pattern comprises a plurality of rings. A ring of the plurality of rings has a distinguishing feature that distinguishes the ring from an adjacent ring. The anterior surface of the cornea reflects the Placido pattern. The camera captures an image of the reflected Placido pattern. The computer: analyzes the image to detect a distortion of the ring that indicates an anomaly of the anterior surface of the cornea; identifies the ring of the plurality of rings according to the distinguishing feature of the ring; and generates the topography of the surface of the cornea that includes the anomaly.

The invention provides tofacitinib nanocrystal eye drops for treating immunity-related eye diseases and a preparation method thereof, and the tofacitinib nanocrystal eye drops are prepared by the following steps: dispersing micronized tofacitinib in a surfactant solution at a high speed, then mixing with a stabilizer, uniformly dispersing, and then carrying out high-pressure homogenization circulation, so as to obtain the tofacitinib nanocrystal eye drops. The tofacitinib nanocrystal eye drops meeting the particle size requirement are obtained. Wherein the surfactant is P188-lecithin, and the stabilizer is any one or a mixture of more of HPMC (Hydroxy Propyl Methyl Cellulose), polyvinyl alcohol and HPMC-docusate sodium. Through cooperation of the surfactant and the stabilizer, the particle size and the potential of the eye drops are influenced, the stability and the adhesiveness are improved, the residence time of the medicine in eyes is prolonged, and the medicine carrying rate is high. The loss speed of the medicine in front of the cornea is reduced, so that the medicine can be slowly released, the eye drop frequency of a patient is reduced, the compliance of the patient is improved, and a good clinical application prospect is achieved.

The invention relates to an anterior segment morphology analysis method, wherein the data acquisition system used by the method comprises a monitoring module, a light splitting module, an eyepiece, anoptical coherence tomography module and a computer. A two-dimensional galvanometer non-contact optical scan is performed on a human eye to collect a three-dimensional data block of the anterior segment of the eye, and the method comprises the following steps of: acquiring the three-dimensional data block of the anterior segment, performing edge extraction on the data block, carrying out rough alignment and fine alignment, fitting, re-sampling and calculating a slope, and finally obtaining the tissue morphology analysis result of the anterior segment, including an anterior segment sectional image, a corneal anterior surface topographic map, a corneal posterior surface topographic map, a corneal thickness map, a crystalline anterior surface topographic map, a crystalline posterior surface topographic map, a crystalline thickness map, a corneal three-dimensional image, a chamber-angle three-dimensional image, an iris three-dimensional image, and a crystalline three-dimensional image. Byusing the method, the complexity of the algorithm is reduced, the measurement accuracy is ensured. The method is non-invasive, has no stimulation, and is easily accepted by patients.

The present invention relates to apparatuses, computer programs, and methods for visual ametropia correction. In a first example, a position of a desired focusing point relative to a retina of an individual eye may be determined, based on obtained topographic information of the anterior surface and of the posterior surface of the cornea, and refractive aberration information for the eye. In a second example, correction information relating to the anterior surface of the cornea may be determined, such as to optimize focusing onto a retina of the eye, based on the obtained topographic information of the anterior surface and of the posterior surface of the cornea and based on obtained topographic information of an anterior surface and of a posterior surface of a lens of the individual eye.