45 results about "Ethylene Oxide Sterilization" patented technology

The invention discloses a medical-grade ultralow-adsorption cycloolefin copolymer (COC) material and a preparation method thereof. According to the material, COC serves as matrix resin, surface-modified nano silicon dioxide is loaded through in-situ polymerization, and a perfluoroalkyl siloxane (PFAS) coating is grafted on the surface of the material through a normal-pressure plasma technology. The preparation method comprises the following steps: surface modification of nano-SiO2, in-situ polymerization of COC, loading of nano-SiO2, and continuous grafting of PFAS with normal-pressure plasma. The adsorption rate of the material is as low as 3.2 * 10 <-7 > copy / mu L (annual loss rate); the temperature from-196 DEG C (liquid nitrogen) to 121 DEG C (autoclaved sterilization) can bear 16,000 g centrifugation without rupture; by means of ethylene oxide sterilization or gamma ray irradiation, it is ensured that the product is free of endotoxin (1t, 0.001 EU / mL), free of DNA enzyme / RNA enzyme residues and other excellent performance, the problems of high adsorption rate and low-temperature brittleness of a traditional COC material in biological sample storage are effectively solved, and the method is suitable for large-scale production of high-end medical cryopreservation tubes and other products.

The application discloses a gelatin-based medical consumable and a sterilization process thereof. The consumable comprises a gelatin main material and a biocompatible auxiliary component. The gelatin is pre-crosslinked to form a three-dimensional network structure, and can be made into a porous sponge, a film, a fiber felt, a particle, a columnar body, a sheet body or a gel block. The sterilization process is used for a pre-crosslinked consumable which has been formed. Radiation sterilization, ethylene oxide sterilization or combined sterilization is adopted. According to the sterilization route, the water content, the packaging atmosphere, the radiation dose, the ethylene oxide concentration and the resolution condition are controlled, so that the sterilization treatment mainly plays a sterilization role and does not damage the gelatin main network. After sterilization, the strength retention rate of the consumable is not less than 85%, the swelling ratio retention rate is not less than 80%, the degradation time change rate is ± 20%, and the gel fraction change rate is not more than 10%.

The present application relates to the technical field of sterilization equipment, in particular to an ethylene oxide sterilization device with multi-bottle piercing function, comprising a whole machine shell, the whole machine shell is provided with a sterilization chamber, a central total cavity and a piercing assembly. The piercing assembly comprises a piercing shell and a single-side piercing device. The single-side piercing device comprises a fixed insertion cylinder, a double-bottle clamp, a piercing assembly, a pressing assembly, a starting limiter and a locking device. The sterilization device described in the case adopts two independent sterilization chambers, and the use scene is more flexible. The sterilization device described in the case only needs one telescopic structure for each single-side piercing device to complete the pressing and piercing of the gas cylinder. When the double-bottle clamp of the single-side piercing device and the ethylene oxide gas cylinder descend to the bottom, the automatic locking can be realized, even if the telescopic structure is misoperated to produce upward action, the double-bottle clamp and the ethylene oxide gas cylinder will remain stable posture, avoiding gas leakage.

The invention discloses a medical sterilization package and a preparation method thereof, the medical sterilization package comprises a matrix film and a functional layer, the secant modulus of the matrix film according to ASTM D882 under 1% strain is 300-2000 MPa, the Talbot stiffness of the matrix film according to GB / T 23144 is 5-25 mN.m, and the air permeability of the matrix film according to GB / T 458 is 20-150 S / 100 mL. The functional layer is coated on the matrix film through at least two times of intaglio printing to form a discontinuous coating, the adjacent coatings form an overlapped structure, the resin content is gradually increased from inside to outside, and pattern projections of the coatings are at least partially staggered so as to form composite breathable pore channels with smaller sizes. The functional layer contains a thermo-sensitive block copolymer and 4, 4 '-oxybis (benzenesulfonyl hydrazide), so that the functional layer maintains low air permeability at room temperature so as to ensure sealing safety, and in an ethylene oxide sterilization temperature interval, a thermo-sensitive polymer chain shrinks and acts with a foaming agent to decompose and produce gas, so that air-permeable pores are expanded, the air permeability is improved, and the sterilization gas penetration effect is optimized.

1. Name of the design product: biological reader (new type of express). 2. Use of the design product: for fast and effective monitoring of the processes of pressure steam sterilization, hydrogen peroxide low-temperature plasma sterilization, ethylene oxide sterilization, low-temperature steam formaldehyde sterilization, peracetic acid sterilization, etc. performed in medical equipment, in combination with the corresponding express biological indicator. 3. Design points of the design product: in shape. 4. Picture or photo best indicating the design points: perspective view.

The application discloses an ethylene oxide sterilization system and a sterilization method, and belongs to the technical field of medical sterilization and disinfection. The system comprises: a plurality of intelligent mobile sterilization units, each unit being a sealed cabin body with autonomous mobile capability, used for accommodating products to be sterilized; a plurality of functional docking stations, including a loading docking station, a pretreatment docking station, a sterilization docking station, an analysis docking station and an unloading docking station arranged in sequence along the unit running path, each docking station being used for docking with the unit and providing corresponding functional support; and an intelligent scheduling control system in communication connection with the units and the docking stations, used for scheduling the mobile path and operation time sequence of the units. The application disperses the sterilization function from the centralized cabinet to a plurality of mobile units, combines the docking stations with different functions, realizes parallel flow line operation of the pretreatment, sterilization and analysis processes, significantly reduces the floor area, improves the sterilization efficiency, enhances the system expansibility, and guarantees the uniformity and stability of the sterilization process.

The invention relates to the technical field of biology, in particular to a sterilization biological indicator and application thereof. The invention provides a biological indicator composed of sulfhydrylated spores containing bacillus atrophaeus and a spore culture solution containing a gold nanoprobe. The biological indicator is used for monitoring the sterilization effect, solves the problems of low spore detection speed of bacillus atrophaeus after ethylene oxide sterilization and high use cost of a rapid ethylene oxide indicator, can realize rapid detection within 10 minutes after sterilization, and does not need a complex instrument. The method has a wide application prospect in the monitoring of the sterilization effect of ethylene oxide sterilization equipment.

The utility model relates to the technical field of ethylene oxide sterilizers, in particular to an ethylene oxide sterilizer special for disposable hygienic products, which is characterized in that a pressure regulating device adopts a stepping vacuum mode, so that the pressure in a sterilizer box body gradually enters a set pressure; then completely gasified EO gas is injected into the sterilizer box body through a dosing device until the concentration is 300-800 mg / L, and the temperature is maintained and controlled to be 30-50 DEG C, so that the sterilization effect is improved; comprising a sterilizer box body and a sterilizer door body, a pick-and-place opening is formed in the sterilizer box body, and the sterilizer door body is installed at the pick-and-place opening; the sterilizer further comprises a steam device, a pressure regulating device, a dosing device and a heating device, the steam device is arranged on the sterilizer box body in a communicating manner and is used for conveying steam into the sterilizer box body, the pressure regulating device is communicated with the sterilizer box body and is used for regulating the pressure in the sterilizer box body, and the dosing device is communicated with the sterilizer box body.

The utility model provides a safe and efficient dosing device for an ethylene oxide sterilizer, which comprises an ethylene oxide steel cylinder and a frame, a panel is arranged on one side of the frame, a touch operation screen and an explosion-proof control box are arranged on the panel, a vaporizer is arranged in the frame, and a temperature sensor and a dosing proportional valve are connected onto the vaporizer; a gas outlet of the ethylene oxide steel cylinder is divided into two paths after passing through the dosing stop valve, one path is connected with an inlet of the vaporizer after passing through the filter, the dosing pneumatic ball valve and the dosing proportional valve, an outlet of the vaporizer is connected with a dosing port of the ethylene oxide sterilizer through the flowmeter, and the pipeline is used for dosing of the ethylene oxide sterilizer; and the other path is connected with a waste gas outlet after being connected with a hand ball valve and is used for treating waste gas in the dosing pipeline. According to the utility model, the nitrogen supply port is connected, so that the sterilization is safer, nitrogen can pass through the hand ball valve, residual ethylene oxide in the dosing pipe is discharged into waste gas treatment, the environment is protected, and combustible gas leakage is avoided.

The utility model discloses an intelligent ethylene oxide sterilization cabinet with multi-parameter cooperative control, which belongs to the technical field of sterilization equipment and comprises a bottom plate and a sterilization cabinet body, a pump body and an ethylene oxide storage box are fixedly mounted at the top of the bottom plate, a gas outlet of the pump body is communicated with a communicating pipe, and the other end of the communicating pipe is communicated with a feeding valve. A mouse cage is slidably mounted in the feeding valve, a supporting plate is fixedly mounted in the mouse cage, a transmission rod is hinged to one side of the supporting plate, a box is fixedly mounted on the outer side of the feeding valve, a rotating shaft is rotatably mounted in the feeding valve, and a connecting rod and a worm gear are fixedly mounted on the outer side of the rotating shaft. On the one hand, incomplete sterilization caused by insufficient gas quantity is avoided, on the other hand, resource waste and potential safety risks caused by excessive gas are prevented, meanwhile, stable flow supply is beneficial to maintaining the stability of pressure and temperature in the sterilization process, and the reliability and repeatability of the whole sterilization process are improved.

The utility model discloses a kind of packaging bags for ethylene oxide disinfection, belong to sanitary product and medical instrument packaging technical field, including packaging body, air hole, dialysis patch, gluing layer and article entrance and exit;Air hole is set on packaging body, dialysis patch is covered on air hole by gluing layer, article entrance and exit are set to the edge of packaging body and with air hole area physical isolation.The utility model provides packaging bag for ethylene oxide disinfection, realizes gas exchange in disinfection stage and microbial barrier dual function in storage stage.The working principle used in the utility model is that the microporous structure of dialysis patch realizes gas selective permeation, and gluing layer is used to ensure the firm combination of dialysis patch and packaging body.

The utility model discloses an ethylene oxide sterilization cabinet which comprises a shell, the bottom of the shell is fixedly connected with a supporting seat, the top wall of the shell is communicated with an air inlet pipe, the bottom end of the air inlet pipe is communicated with a flow dividing pipe, the inside of the flow dividing pipe is communicated with an air spraying pipe, and the bottom of the air spraying pipe is communicated with a plurality of air spraying heads. The flow dividing pipe and the air spraying pipe are communicated with the shell, the front face of the shell is movably connected with a connecting door, the bottom of the inner side of the shell is fixedly connected with a placing net plate, and the bottom of the shell is fixedly connected with a purifying unit. According to the utility model, through the arrangement of the purification unit, after articles are sterilized, an external power supply is used for supplying power to the fan box, and meanwhile, the scavenging valve is opened to exhaust gas in the box body, so that negative pressure is generated in the box body, and gas with ethylene oxide in the shell is pumped into the box body through the connecting pipe; and then irradiating through a UA ultraviolet photolysis lamp.

The utility model discloses an extracorporeal circulation puncture suite which comprises a dilator, a puncture accessory and a suture accessory, and the dilator used for blood vessel dilation, the puncture accessory used for puncture and the suture accessory used for fixing a pipeline are sealed in a packaging bag body after being sterilized through ethylene oxide. The dilator is provided with dilation heads for dilating blood vessels continuously in a staged mode, and the number of the dilation heads on the dilator can be adjusted. The extracorporeal circulation puncture kit has the advantages that the multi-stage dilator with the adjustable dilation head in the extracorporeal circulation puncture kit is used for performing staged continuous dilation on blood vessels, repeated replacement of the dilator is avoided, the risk of infection of a patient is reduced while the operation efficiency is improved, and due to the staged continuous dilation, intubation tubes of different specifications are high in universality and high in practicability. Due to the design that the hydrophilic coating and the hardening material are additionally arranged on the guide wire, the surface of the guide wire is smoother, puncture catheterization is smoother and more accurate, due to the arrangement of the suture accessory, the problems of intubation fixing and skin wound suture are solved in a clinical one-stop mode, and the preparation workload of clinical operations is reduced.

The invention discloses a preparation method of an antibacterial suture line with passivated barbs, and relates to the technical field of medical suture lines. According to the method, core layer and shell layer spinning solutions are prepared, and core-shell structure monofilaments are formed through coaxial electrostatic spinning; the passivated barbs are precisely machined through femtosecond laser, the barb area is locally thinned, and then the antibacterial suture line with the passivated barbs is obtained through antibacterial coating liquid coating, vacuum drying, ethylene oxide sterilization and heat setting. The antibacterial coating liquid is prepared from chitosan, an acetic acid aqueous solution, an antibacterial component and a cross-linking agent. Through the synergistic effect of a core-shell structure and a dual antibacterial system, the long-acting antibacterial property and the mechanical property are considered; the barb form is optimized through femtosecond laser processing, and tissue damage is reduced; the balance of biocompatibility, operation performance and degradation rate is realized through material and process regulation and control, and the suture needle is suitable for clinical surgical wound suture and can reduce infection risk and pain of patients.

This application provides a method for forming an antimicrobial coating on the surface of an implantable device and the implantable device itself. The method for forming an antimicrobial coating on the surface of an implantable device includes the following steps: placing the implantable device in an isolation box; setting an antimicrobial carrier assembly on the outer surface of the isolation box and / or the inner surface of a sterile barrier packaging; placing the isolation box in the sterile barrier packaging and sealing it to obtain a packaging system; sterilizing the packaging system with ethylene oxide; and vacuum dehydrating the ethylene oxide-sterilized packaging system. This method utilizes the antimicrobial carrier assembly in the packaging structure to diffuse an antimicrobial agent onto the surface of the implantable device during the sterilization and dehydration cycle, enabling the originally uncoated implantable device to acquire stable and controllable surface antimicrobial properties, thereby improving the antimicrobial capability of the implantable device.

1. The name of the design product: the front panel of ethylene oxide analyzer. 2. The use of the design product: the ethylene oxide analyzer is a special equipment for decomposing the ethylene oxide gas discharged after the use of the ethylene oxide sterilization cabinet, and the front panel of the ethylene oxide analyzer is used for information display. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: front view. 5. The bottom surface of the design product is not easily visible or invisible during use, and the top view is omitted. 6. Other circumstances that need to be explained: the design is a partial design, and the protected part is the part outside the red transparent area in the picture.

This application relates to an ethylene oxide sterilization waste gas treatment system and method. The system includes a tower, a circulation tank, a circulating cooler, and a waste gas post-treatment device. An air inlet is located on one side of the tower, and a heater is installed at the inlet. The circulation tank is connected to the bottom of the tower and contains absorbent liquid. A demister layer, a spray gun, and a packing layer are sequentially arranged inside the tower. The spray gun is connected to the circulation tank via a circulating liquid pipe, and the circulating cooler is installed on the circulating liquid pipe. The top of the tower is connected to the waste gas post-treatment device. Ethylene oxide-containing waste gas enters the tower, undergoes mass transfer with the absorbent liquid sprayed from the spray gun, and then enters the waste gas post-treatment device for treatment and discharge. Carrier gas, after being heated, enters the tower, undergoes mass transfer with the ethylene oxide-containing absorbent liquid, and then enters the waste gas post-treatment device for treatment and discharge. This application solves the technical problem of equipment consuming large amounts of natural gas or electricity during periods without waste gas generation.

The application discloses a preparation method of an antibacterial suture with passivated barbs, and relates to the technical field of medical sutures. The method comprises the following steps: preparing a core layer and a shell layer spinning solution, and forming a core-shell structure monofilament through coaxial electrospinning; adopting femtosecond laser precision machining to passivate the barbs, and locally thinning the barb area, and then coating an antibacterial coating liquid, vacuum drying, ethylene oxide sterilization and heat setting to obtain the antibacterial suture with passivated barbs. The antibacterial coating liquid is prepared from chitosan, an acetic acid aqueous solution, an antibacterial component and a crosslinking agent. Through the synergistic effect of the core-shell structure and the double antibacterial system, the application takes into account long-acting antibacterial property and mechanical property; the femtosecond laser machining optimizes the barb morphology and reduces tissue damage; and the material and process regulation achieve the balance of biocompatibility, operation performance and degradation rate, and is suitable for clinical surgical wound suturing, and can reduce the risk of infection and the pain of patients.

This invention discloses a polyglycolic acid (PGA) suture-silk suture composite braided surgical suture and its preparation method. The suture is composed of two absorbable surgical sutures (PGA) and two non-absorbable surgical sutures (silk threads) in a multi-strand braided structure. The silk threads are black in color, and their main component is silk fibroin with a molecular weight greater than 30,000. The PGA sutures are pre-dyed with D&C Violet No. 2 dye before braiding, and then heat-set and sterilized with ethylene oxide after braiding. This invention utilizes the dense structure formed by the multi-strand braid to effectively prevent wound exudate from seeping into the suture interior, reducing the corrosive effect of liquid on the internal materials. Simultaneously, through the synergistic composite of PGA sutures and silk threads, a coordinated match is achieved between the suture's mechanical strength and degradation characteristics, resulting in a suture that combines stable support with suitable degradability, better meeting the needs of general soft tissue suturing and ligation in clinical practice.

The invention belongs to the technical field of electrophysiological detection, and relates to a high-flux cortical deep electrode debugging, sterilizing and intraoperative taking device which comprises a transparent shell with holes, a silica gel partition plate with clamping grooves and an ethylene oxide compatible line concentration module. The test result shows that the transparent shell with the holes and the silica gel partition plate with the clamping groove completely fix the electrode, and the situation that the tip of the electrode mistakenly touches the shell or other parts in the whole process of debugging, transporting, sterilizing or taking can be avoided. According to the device, ethylene oxide sterilization of the whole module can be directly carried out under the condition that all modules of the electrode are connected under the condition that the shell is not opened, and the time for assembling and debugging the electrode module in an operation is obviously saved. The ethylene oxide compatible line concentration module can quickly release the data line in an operation, plays a role in mechanical protection and electromagnetic shielding on the data line, and is suitable for a complex electromagnetic environment and a complex mechanical environment of an operating room.

The utility model provides a toxic gas emission monitoring and alarming device for an ethylene oxide sterilizer, which relates to the field of ethylene oxide sterilizers and comprises a sterilizer body, a display and an alarm are respectively fixed on one side of the sterilizer body, and ethylene oxide detection equipment is arranged on one side of the sterilizer body. The ethylene oxide detection equipment is communicated with the sterilizer body through an exhaust pipe, one side of the ethylene oxide detection equipment is communicated with a flow dividing box, and one side of the flow dividing box is communicated with a gas outlet pipe. At the moment, under the reverse movement of the driving assembly, the first cover plate and the second cover plate can be driven to move reversely, at the moment, the first cover plate closes the gas outlet pipe, and the second cover plate opens the return pipe, so that the toxic gas can be conveyed into the sterilizer body again through the return pipe, and the toxic gas can be sufficiently conveyed and treated conveniently; the treatment efficiency of the toxic gas is improved.

This utility model relates to the field of ethylene oxide sterilization technology, specifically to an ethylene oxide sterilization waste gas treatment device, including a purification chamber and a spraying device. A water tank is located at the bottom of the purification chamber. The spraying device includes a first spray frame with an annular channel inside the purification chamber, a second spray frame located inside the purification chamber and directly above the annular channel, multiple nozzles mounted on the first and second spray frames, a pump body mounted on the water tank, conduits connected at both ends to the pump body and the second spray frame respectively, and branch pipes mounted on the conduits and connected to the first spray frame. The cross-sectional diameter of the second spray frame is larger than the orifice diameter of the channel. This utility model can improve the reaction rate between waste gas and water, thus enhancing the practicality of the device.

The application belongs to the technical field of electrophysiological detection, and relates to a high-throughput deep cortex electrode debugging, sterilization and intraoperative use device.The device comprises a transparent hole shell, a silica gel separation plate with a clamping groove and an ethylene oxide compatible hub module.Test results show that the transparent hole shell and the silica gel separation plate with the clamping groove completely fix the electrode, and can avoid the tip of the electrode from being accidentally touched with the shell or other parts during the whole process of debugging, transportation, sterilization or use.The device can directly perform ethylene oxide sterilization on the connection of each module of the electrode without opening the shell, and obviously saves the time for assembling the electrode modules and debugging during the operation.Using the ethylene oxide compatible hub module can quickly release the data line during the operation, and the data line is mechanically protected and electromagnetically shielded, and is suitable for the complex electromagnetic environment and mechanical environment in the operating room.

The invention relates to the field of ethylene oxide sterilizers, and particularly discloses a penetration type ethylene oxide sterilizer which comprises a sterilization main pipe which is formed by connecting a plurality of branch pipes end to end, and the branch pipes can be independently sealed and can be communicated with one another; an internal circulation heating system; the hot air pipe is mounted outside the sterilization box, and the air inlet end and the air outlet end of the hot air pipe are communicated with the branch pipes; the heating piece is mounted on the inner wall of the hot air pipe; the circulating air supply impeller is rotationally mounted in the hot air pipe; and the driving mechanism is used for converting heat energy of the heating piece into kinetic energy to drive the circulating air supply impeller to rotate. The method has the effect of reducing energy consumption.

This utility model discloses an ethylene oxide sterilization tail gas purification device, including a purification chamber. An inlet pipe and an outlet pipe are respectively installed through the upper and lower ends of the purification chamber. A support foot is fixedly connected to the lower surface of the purification chamber on the side of the outlet pipe. A positioning arm is movably arranged at the edge of the lower surface of the purification chamber, and a door is fixedly connected to the upper end of the positioning arm. A positioning ring is fixedly installed on the upper inner wall of the purification chamber, and a filter frame is movably arranged on the inner wall of the positioning ring. A filter screen is fixedly installed on the lower inner wall of the filter frame. An adjusting ring is sleeved on the outer wall of the inlet pipe, and a locking rod is fixedly connected to the upper surface of the purification chamber on the side of the adjusting ring. A limit mechanism is provided on the lower outer wall of the adjusting ring. This ethylene oxide sterilization tail gas purification device facilitates the replacement of the filter screen and catalyst, thereby ensuring the stability of the device and improving its practicality.

The present application relates to the medical dressing processing and manufacturing field, disclose a kind of waterproof breathable medical dressing and preparation method thereof.The method uses staged gradient assembly technology, sequentially include: first chitosan is prepared into spinning dope, nanofiber membrane is prepared by electrospinning, and is hot-pressed into composite base layer with pretreated PTFE hydrophobic membrane, then special medical pressure-sensitive adhesive is coated to obtain semi-finished product;Can add coaxial spinning core-shell structure fiber membrane, silica gel impermeable ring, release layer, finally sterilized by ethylene oxide, laser cutting to obtain finished product.The present application makes the dressing have efficient waterproof, balanced ventilation performance by material compounding and process optimization, chitosan fiber is compatible with wound surface, adsorbs exudate, PTFE membrane blocks external pollutants, firm interlayer bonding, adhesive layer is pasted smoothly and easily peeled off, overall biocompatibility is good, convenient to use, adapt to various wound care needs, process controllable and easy to scale production.

The invention discloses an ethylene oxide resolver, and relates to the technical field of medical instruments, the ethylene oxide resolver comprises a box body, the top of the box body is fixedly connected with a controller, one side wall of the box body is fixedly connected with a touch screen, a power-off button and a power-on button, and the bottom of the box body is fixedly connected with a mounting rack; the upper end of the mounting frame is fixedly connected with a high-temperature catalytic resolver, the top of the high-temperature catalytic resolver is fixedly connected with a heater, and a gas conveying mechanism used for conveying ethylene oxide to the high-temperature catalytic resolver is arranged in the box body; according to the present invention, the tail gas discharged during the operation of the ethylene oxide sterilizer is subjected to the high-temperature catalytic decomposition reaction through the catalyst, such that the harmless treatment is compulsively achieved, and the safe emission standard is ensured; worries of users are thoroughly eliminated, and the decomposition efficiency is up to 99.99% or above.

The present application relates to the technical fields of ethylene oxide sterilizer, and discloses a kind of penetrating ethylene oxide sterilizer, including sterilizer main body, gas pipe and exhaust pipe, the bottom side of the inside of sterilizer main body is provided with bearing table, the bearing table is provided with inner cavity, the top of the bearing table is provided with gas outlet structure, one end of the gas pipe is communicated with the inner cavity of bearing table and passes through sterilizer main body and bearing table.The bearing table and telescopic pipeline device of the present application are set, when using, the article to be sterilized can be placed on the bearing table, then the article is restricted between bearing table and telescopic pipeline device by telescopic pipeline device, then ethylene oxide sterilization gas enters bearing table from gas pipe, and the article is discharged from telescopic pipeline device, compared with prior art, the space of sterilization is reduced, and the sterilization effect and sterilization efficiency of prior art are effectively improved by the way of penetration.

The present disclosure provides an ethylene oxide sterilization sensor and method of use. The sensor includes: at least one thermal indicator component independently selected from an electronic thermal sensor, an irreversible temperature indicator, and a heat-shrinkable film; an acid-functional porous sorbent or an acid-functional nonwoven fibrous substrate in thermal contact with the at least one thermal indicator component; and an acid having a boiling point above 120° C. and a pKa of no greater than 2.5. The acid is impregnated in or covalently attached to the porous sorbent or is covalently attached to the nonwoven fibrous substrate. The sensor includes at least one of the electronic thermal sensor, the irreversible temperature indicator, or the acid-functional nonwoven fibrous substrate.