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33 results about "Keratoprosthesis" patented technology
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Keratoprosthesis is a surgical procedure where a diseased cornea is replaced with an artificial cornea. Traditionally, keratoprosthesis is recommended after a person has had a failure of one or more donor corneal transplants. More recently, a less invasive, non-penetrating artificial cornea has been developed which can be used in more routine cases of corneal blindness. While conventional cornea transplant uses donor tissue for transplant, an artificial cornea is used in the Keratoprosthesis procedure. The surgery is performed to restore vision in patients suffering from severely damaged cornea due to congenital birth defects, infections, injuries and burns.
Corneal implant and uses thereof
A membrane for corneal implant or keratoprosthesis comprising a biological polymer and a polyacrylamide is described. The mixture of both polymers produces a hydrogel that becomes a transparent film or membrane upon drying. The resulting device and tissue engineered implants are useful for biomedical applications of the cornea, such as tissue repair and transplantation.
Owner:OTTAVA HEALTH RES INST (CA) +1
Keratoprosthesis
InactiveUS20140142200A1Easy to controlImprove consistent qualityBiocideAbsorbent padsWound dressingArtificial cornea
The invention comprises a method of making molded, double-crosslinked (i.e., two stages of crosslinking), transparent, collagen materials using a novel combination of diafiltration, lyophilization, and homogenization. The collagen material can be used not only as an ophthalmic device, but also as a tissue scaffold, drug delivery device, wound dressing, or other collagen hydrogel based device.
Owner:EYEGENIX
Transcorneal vision assistance device
The invention provides a transcorneal vision assistance device implantable in the eye of a patient. A preferred embodiment transcorneal microtelescope vision assistance device is implantable in the eye of a patient and includes a keratoprosthesis configured to replace a portion of the cornea of a patient and to secure the keratoprosthesis to a remaining front portion of the cornea. A microtelescope is carried by the keratoprosthesis for transcorneal mounting of the microtelescope.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Suturable Hybrid Superporous Hydrogel Keratoprosthesis for Cornea
The present invention features a hybrid superporous hydrogel scaffold for cornea regeneration and a method for producing the same. The hybrid hydrogel is composed of a superporous poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(methyl methacrylate) (PMMA) copolymer mixed with collagen. The hybrid scaffold can be used as a suturable hybrid corneal implant or keratoprosthesis.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Suturable hybrid superporous hydrogel keratoprosthesis for cornea
InactiveUS20160144069A1Eye implantsPharmaceutical delivery mechanismProsthesisPoly(methyl methacrylate)
The present invention features a superporous hydrogel scaffold for corneal regeneration or replacement and a method for producing the same. The superporous hydrogel is composed of a poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(methyl methacrylate) (PMMA) copolymer mixed with collagen. The scaffold can be used as a suturable hybrid corneal implant or keratoprosthesis.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Keratoprosthesis and manufacturing method thereof
ActiveCN103830021AAvoid separationPrevent leakageEye implantsOptical articlesFiberBiocompatibility Testing
The invention belongs to the field of biomedical engineering, and relates to a keratoprosthesis and a manufacturing method of the keratoprosthesis. The keratoprosthesis comprises a spherical-crown-shaped keratoprosthesis body optical function area and a spherical-zone-shaped supporting area, wherein the keratoprosthesis body optical function area is combined with the supporting area, and the joint part of the keratoprosthesis body optical function area and the supporting area, interlaced and converged, is of an integrated transition structure; the keratoprosthesis body optical function area is made of PHEMA hydrogel good in biocompatibility and light transmission, the supporting area is composed of a PHEMA porous scaffold evenly reinforced by fibroin fibers, and the keratoprosthesis body optical function area and the supporting area are naturally connected in an integrated mode. The results of cell tests and animal tests show that the keratoprosthesis is good in biocompatibility, histocompatibility and flexibility and resistant to tear, facilitates suture, supports biology heal between the cambium and a carina support, can stop aqueous fluid from leakage and infection and can effectively avoid spontaneity dislocation after a transplant.
Owner:EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
Novel assembly type keratoprosthesis
The invention relates to the field of biomedical engineering, and in particular relates to a novel assembly type keratoprosthesis. The assembly type keratoprosthesis provided by the invention comprises a central optical part and a fixed support part, wherein the central optical part comprises a spherical cover body and a cylindrical transparent body; the upper surface of the spherical cover body is a spherical face, and while the lower surface of the spherical cover body is connected with the upper surface of the cylindrical transparent body; through holes are arranged at the middle of the fixed support part; fixed rings are arranged on the sidewalls of the through holes; and the cylindrical transparent body passes through the fixed support part through the through holes. As being verified in a lagophthalmos animal experiment, the novel assembly type keratoprosthesis has the functions of promoting the tissue to quickly grow to achieve good healing, increasing the firmness of the keratoprosthesis and reducing the complications such as detaching, offsetting, water leaking, edema in surrounding tissue of keratoprosthesis and dissolving With the adoption of the assembly type keratoprosthesis, the incidence rate of anterior and posterior cylinder fibrosis proliferative membrances of the keratoprosthesis can be reduced in clinic, and the keratoprosthesis and the tissue in the lamellar cornea can be promoted to heal well.
Owner:SHANGHAI RES CENT OF BIOMEDICAL ENG
Artificial cornea
The present invention provides an artificial cornea (keratoprosthesis) that may be implanted into a patient in need thereof. The artificial cornea comprises a rigid transparent central core surrounded by a peripheral skirt comprising a porous hydrogel. Methods of making such artificial corneas are also provided.
Owner:UNIV OF WASHINGTON
Fiber-enhanced drug-loading hydrogel keratoprosthesis skirt stent and preparation method thereof
The invention belongs to the field of keratoprosthesis stent materials and provides a fiber-enhanced drug-loading hydrogel keratoprosthesis skirt stent and a preparation method thereof. The skirt stent comprises the following components in percentage by weight: 6wt%-10wt% of fibers, 8wt%-15wt% of biodegradable drug-loading microspheres and 75wt%-86wt% of hydrophilic hydrogel, wherein the fibers are disorderedly distributed in hydrophilic hydrogel. The fiber-enhanced drug-loading hydrogel keratoprosthesis skirt stent has special excellent biocompatibility and permeability of hydrogel and very high tensile strength; the inflammations and complications occurring after the corneal transplantation can be relieved by virtue of drugs released by the biodegradable drug-loading microspheres.
Owner:SICHUAN UNIV
Keratoprosthesis
InactiveCN102727324AWon't move slowlyReduce structural strengthEye implantsEngineeringUltimate tensile strength
The invention relates to the field of medical treatment, and in particular relates to a keratoprosthesi. The keratoprosthesis comprises a frame and a cylindrical lens, wherein the frame is of a shape of a smaller part of a spherical surface which is cut off by a reference surface, and the center of the frame is provided with a central hole; the inner wall of the central hole is provided with internal threads; the frame comprises a main body and a metal net which is embedded in the main body; the extension direction of the metal net is consistent with the extension direction of the main body; and the outer wall of the cylindrical lens is provided with external threads which are matched with the internal threads. Compared with the prior art, according to the keratoprosthesi, the frame is designed in the way of comprising two parts of the main body and the metal net which is embedded in the main body, and because the human eye tissue and medical resin have higher compatibility, the human eye tissue can grow together with the main body, and cannot slowly push the main body to move towards the outside; but the medical resin material is crisper and lower structural strength, the structural strength of the frame can be improved through embedding the metal net into the frame, so the frame is not easy to be damaged.
Owner:于好勇
Novel keratoprosthesis, and system and method of corneal repair using same
ActiveUS20150216651A1Improved soft tissue adhesionLess squeezeEye implantsAcid etchingAnterior cornea
A keratoprosthesis and system and method of using same for corneal repair. The keratoprosthesis comprises a biocompatible support and an optic member disposed through a channel within the support. The support includes metal, preferably titanium, and treated, such as by sandblasting and / or acid etching, to create textured surfaces that promote soft tissue adhesion. A locking member interconnects the optic member and support. An outer surface of the locking member a collar extending from the support and disposed around the optic member is also metal, preferably titanium, and is similarly treated to promote soft tissue adhesion. A locking member interconnects the optic member and support. The system includes the keratoprosthesis positioned within an isolated soft tissue segment of a non-ocular tissue, such as buccal mucosa, placed on the anterior cornea. The method includes removing corneal epithelium, isolating and transplanting a segment of soft tissue to the de-epithelialized cornea, creating a receiving area in the soft tissue, positioning a keratoprosthesis relative to the receiving area anterior to the cornea, and securing the keratoprosthesis.
Owner:UNIV OF MIAMI
Simulation eye
ActiveCN105551358ASimple structureEasy to operateEducational modelsEthylene diaminePolyethylene glycol
The present invention provides simulation eye. The simulation eye comprises transparent keratoprosthesis and a sealed cylindrical housing; the keratoprosthesis is fixed at one end of the housing and has a middle part which is projected outwards in a spherical surface shape, and a concave spherical artificial fundus corresponding to the keratoprosthesis is fixed at the other end of the housing; the outer wall of the housing is provided with an electrode layer, and the inner wall of the housing is provided with hydrophobic dielectric layers; an insulation ring configured to separate the electrode layer from the hydrophobic dielectric layers is fixed at the middle part of the housing, and the insulation ring divides the inner cavity of the housing into a front cavity, a middle cavity and a back cavity, wherein the middle cavity corresponds to the insulation ring, and the front cavity and the back cavity respectively correspond to the hydrophobic dielectric layers at two side of the insulation ring; a conductive polar liquid is arranged in the middle cavity, and an insulated non-polar liquid is arranged in the front cavity and the back cavity; and the polar liquid and the insulated non-polar liquid have same density and different refractive indexes and cannot dissolve with each other, the polar liquid communicates the anode of a direct current power supply, and the electrode layer communicates to the cathode of the direct current power supply. The polar liquid comprises aqueous solution containing salt, ethylene diamine tetraacetic acid and polyethylene glycol.
Owner:THE EYE HOSPITAL OF WENZHOU MEDICAL UNIV
Method of removing unwanted deposits from a keratoprosthesis in vivo
A method of applying a solution in vivo made up of chelating agent(s) such as enzymes and / or surfactants in such a composition to the anterior surface of a keratoprosthesis as to remove deposits and unwanted debris from its surface while maintaining the integrity of the keratoprosthesis.
Owner:MYER DAN L
Beta-tricalcium phosphate/polyvinyl alcohol composite hydrogel keratoprosthesis porous support material and preparation method thereof
InactiveCN102580157AGood biocompatibilityGood mechanical propertiesProsthesisWater bathsBiocompatibility Testing
The invention discloses a beta-tricalcium phosphate / polyvinyl alcohol composite hydrogel keratoprosthesis porous support material and a preparation method thereof. The preparation method provided by the invention comprises the following steps of 1, adding polyvinyl alcohol into a dimethyl sulfoxide aqueous solution, and heating at a constant temperature to obtain polyvinyl alcohol hydrogel, 2, directly adding beta-tricalcium phosphate and a pore forming agent into the polyvinyl alcohol hydrogel, and carrying out isothermal stirring in a water bath to obtain a mixture, 3, directly injecting the mixture into an aseptic mold, and carrying out repeated refrigeration molding, and 4, immersing the mixture subjected to refrigeration molding in aseptic deionized water, and carrying out iodophor disinfection to obtain the beta-tricalcium phosphate / polyvinyl alcohol composite hydrogel keratoprosthesis porous support material. The preparation method provided by the invention can realize material preparation under normal pressure, has simple processes, and can realizes preparation of the beta-tricalcium phosphate / polyvinyl alcohol composite hydrogel keratoprosthesis porous support material which has good biocompatibility, good mechanical properties and high water content.
Owner:深圳华明生物科技有限公司
Keratoprosthesis
A keratoprosthesis includes an anterior collagen layer made of transparent synthetic collagen, and a hydrophobic posterior layer, an anterior surface of the posterior layer being posterior of an anterior surface of the collagen layer.
Owner:EYEYON MEDICAL
Transcorneal vision assistance device
The invention provides a transcorneal vision assistance device implantable in the eye of a patient. A preferred embodiment transcorneal microtelescope vision assistance device is implantable in the eye of a patient and includes a keratoprosthesis configured to replace a portion of the cornea of a patient and to secure the keratoprosthesis to a remaining front portion of the cornea. A microtelescope is carried by the keratoprosthesis for transcorneal mounting of the microtelescope.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Keratoprosthesis optical center area and preparation method thereof and keratoprosthesis
InactiveCN106362207AGood optical performanceGood water storageEye implantsTissue regenerationProsthesisTransmittance
The invention belongs to the field of prosthesis materials, and provides a keratoprosthesis optical center area. The keratoprosthesis optical center area is a surface-heparinized keratoprosthesis center material, and the surface-heparinized keratoprosthesis center material comprises a keratoprosthesis center material and a chemical modifier; the chemical modifier comprises a silane coupling agent and a heparin derivative or heparinoid derivative with anti-adhesion performance. According to the keratoprosthesis optical center area, the surface of polyvinyl alcohol hydrogel is chemically modified with the heparin derivative or the heparinoid derivative, and the excellent hydrophilia and high electronegativity of the heparin derivative or the heparinoid derivative are utilized, so that the keratoprosthesis center material with the surface provided with or containing the heparin derivative or the heparinoid derivative shows cell adhesive resistance. In addition, the keratoprosthesis optical center area is good in optical performance, water storage performance, swelling property and hydrophilic performance and high visible light transmittance.
Owner:SHENZHEN UNIV
Special tool for keratoprosthesis
ActiveCN104434392AReduced operating proficiency requirementsEasy to installEye surgeryEngineeringTherapeutic effect
The invention relates to the technical field of medical instruments, in particular to a special tool for keratoprosthesis. The special tool comprises a handle and a mounting tool head; the mounting tool head comprises a first trepan disposed on the handle and used for drilling tissues in a mount. According to the special tool, the mounting tool head disposed on the handle comprises the first trepan. During usage of the special tool, a surgeon holds the handle by hand, inserts the first trepan into the mount and drills the tissues in the mount. The special tool is simple to operate, has low requirement on operational skillfulness of the surgeon and allows visualization of the tissues in the mount, advantages are made for following mounting of a cylindrical lens, the cylindrical lens is mounted accurately, and therapeutic effect is guaranteed.
Owner:BEIJING MICROKPRO MEDICAL INSTR CO LTD
A kind of artificial cornea and preparation method thereof
ActiveCN103830021BGood biocompatibilityGood blood compatibilityEye implantsOptical articlesFiberBand shape
The invention belongs to the field of biomedical engineering, and relates to a keratoprosthesis and a manufacturing method of the keratoprosthesis. The keratoprosthesis comprises a spherical-crown-shaped keratoprosthesis body optical function area and a spherical-zone-shaped supporting area, wherein the keratoprosthesis body optical function area is combined with the supporting area, and the joint part of the keratoprosthesis body optical function area and the supporting area, interlaced and converged, is of an integrated transition structure; the keratoprosthesis body optical function area is made of PHEMA hydrogel good in biocompatibility and light transmission, the supporting area is composed of a PHEMA porous scaffold evenly reinforced by fibroin fibers, and the keratoprosthesis body optical function area and the supporting area are naturally connected in an integrated mode. The results of cell tests and animal tests show that the keratoprosthesis is good in biocompatibility, histocompatibility and flexibility and resistant to tear, facilitates suture, supports biology heal between the cambium and a carina support, can stop aqueous fluid from leakage and infection and can effectively avoid spontaneity dislocation after a transplant.
Owner:EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
A suturable hybrid superporous hydrogel keratoprosthesis for cornea
InactiveCN104144716AEye implantsMammal material medical ingredients(Hydroxyethyl)methacrylateMethacrylate methyl
The present invention features a hybrid superporous hydrogel scaffold for cornea regeneration and a method for producing the same. The hybrid hydrogel is composed of a superporous poly (2-hydroxyethyl methacrylate) (PHEMA) and poly (methyl methacrylate) (PMMA) copolymer mixed with collagen. The hybrid scaffold can be used as a suturable hybrid corneal implant or keratoprosthesis.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Keratoprosthesis, and system and method of corneal repair using same
A keratoprosthesis and system and method of using same for corneal repair. The keratoprosthesis comprises a biocompatible support and an optic member disposed through a channel within the support. The support includes metal, preferably titanium, and treated, such as by sandblasting and / or acid etching, to create textured surfaces that promote soft tissue adhesion. A locking member interconnects the optic member and support. An outer surface of the locking member a collar extending from the support and disposed around the optic member is also metal, preferably titanium, and is similarly treated to promote soft tissue adhesion. A locking member interconnects the optic member and support. The system includes the keratoprosthesis positioned within an isolated soft tissue segment of a non-ocular tissue, such as buccal mucosa, placed on the anterior cornea. The method includes removing corneal epithelium, isolating and transplanting a segment of soft tissue to the de-epithelialized cornea, creating a receiving area in the soft tissue, positioning a keratoprosthesis relative to the receiving area anterior to the cornea, and securing the keratoprosthesis.
Owner:UNIV OF MIAMI
A fiber-reinforced drug-loaded hydrogel artificial corneal skirt support and its preparation method
The invention belongs to the field of keratoprosthesis stent materials and provides a fiber-enhanced drug-loading hydrogel keratoprosthesis skirt stent and a preparation method thereof. The skirt stent comprises the following components in percentage by weight: 6wt%-10wt% of fibers, 8wt%-15wt% of biodegradable drug-loading microspheres and 75wt%-86wt% of hydrophilic hydrogel, wherein the fibers are disorderedly distributed in hydrophilic hydrogel. The fiber-enhanced drug-loading hydrogel keratoprosthesis skirt stent has special excellent biocompatibility and permeability of hydrogel and very high tensile strength; the inflammations and complications occurring after the corneal transplantation can be relieved by virtue of drugs released by the biodegradable drug-loading microspheres.
Owner:SICHUAN UNIV
Silicone monomer
ActiveUS8580904B2High in siliconeImprove hydrophilicitySilicon organic compoundsTissue regenerationMonomer compositionPolymer science
Owner:NOF CORP
Artificial cornea and its preparation method
The invention discloses a keratoprosthesis. The keratoprosthesis has antibacterial activity. The keratoprosthesis comprises a porous peripheral support part and an optical center part. The porous peripheral support part comprises an antibacterial chitosan derivative, polyvinyl alcohol and a nano-phosphate. The optical center part comprises polyvinyl alcohol hydrogel and hydroxyethyl methacrylate hydrogel. The invention also discloses a preparation method of the keratoprosthesis. The keratoprosthesis has good biocompatibility and infection resistance and can promote fast healing of surgical wounds.
Owner:深圳华明生物科技有限公司
Novel assembly type keratoprosthesis
The invention relates to the field of biomedical engineering, and in particular relates to a novel assembly type keratoprosthesis. The assembly type keratoprosthesis provided by the invention comprises a central optical part and a fixed support part, wherein the central optical part comprises a spherical cover body and a cylindrical transparent body; the upper surface of the spherical cover body is a spherical face, and while the lower surface of the spherical cover body is connected with the upper surface of the cylindrical transparent body; through holes are arranged at the middle of the fixed support part; fixed rings are arranged on the sidewalls of the through holes; and the cylindrical transparent body passes through the fixed support part through the through holes. As being verified in a lagophthalmos animal experiment, the novel assembly type keratoprosthesis has the functions of promoting the tissue to quickly grow to achieve good healing, increasing the firmness of the keratoprosthesis and reducing the complications such as detaching, offsetting, water leaking, edema in surrounding tissue of keratoprosthesis and dissolving With the adoption of the assembly type keratoprosthesis, the incidence rate of anterior and posterior cylinder fibrosis proliferative membrances of the keratoprosthesis can be reduced in clinic, and the keratoprosthesis and the tissue in the lamellar cornea can be promoted to heal well.
Owner:SHANGHAI RES CENT OF BIOMEDICAL ENG
Keratoprosthesis
InactiveCN106491242AMild inflammatory responseKeep the inherent characteristicsEye implantsPharmaceutical delivery mechanismMicroorganismAqueous humor
The invention discloses a keratoprosthesis. The keratoprosthesis comprises a central opticator and a fixed portion arranged in the periphery, and the keratoprosthesis is characterized in that a hydroxylapatite coating (3) is smeared on a cylinder lateral outer surface of the central opticator and the inner surface of the fixed portion (2) in the keratoprosthesis, and average grain diameter of nanoparticle of the coating is 20 nm. The keratoprosthesis has the advantages that isolation of the coating and an anti-microbial property of the hydroxylapatite are made use of, after smearing the coating and the hydroxylapatite on the cylinder outer surface of the keratoprosthesis opticator and the inner surface of the fixed portion of the periphery of the opticator, a role of killing effect on microorganisms such as germs which are in contact with a cornea and aqueous humor of a patient is thus played by the coating and the hydroxylapatite; due to the fact that the hydroxylapatite can smear the periphery of the keratoprosthesis opticator for a long time, intrinsic characteristics of keratoprosthesis materials are not changed, intrinsic characteristics of the keratoprosthesis are still maintained so that treatment and nursing can reach optimal effects.
Owner:黄一飞 +1
A kind of artificial cornea with nano-ultra-thin biofilm differentially modifying the front and rear surfaces and its production method
ActiveCN104436302BPromote growthGrowth promotion and maintenanceEye implantsCoatingsPostoperative complicationBiological membrane
The invention relates to a keratoprosthesis with front and back surfaces differently ornamented by a nanometer ultrathin biological membrane and a preparation method. The invention aims to provide the keratoprosthesis for reducing keratoprosthesis postoperative complications. The provided preparation method is simple, practicable and pollution-free. According to the keratoprosthesis with front and back surfaces differently ornamented by the nanometer ultrathin biological membrane, polycation layers and epidermal growth factor layers are repeatedly deposited on the front surface of an optical part sequentially, the polycation layers and HA layers are repeatedly deposited on the rear surface of the optical part from inside to outside sequentially, and the outmost layer is the HA layer. The preparation method of the keratoprosthesis with front and back surfaces differently ornamented by the nanometer ultrathin biological membrane sequentially comprises the following steps: (1) charging negative charge to the surface of the keratoprosthesis; (2) alternately absorbing polycations and epidermal growth factors on the front surface of the keratoprosthesis; (3) alternately absorbing the polycations and HA on the rear surface of the keratoprosthesis; and (4) drying and carrying out seal packing.
Owner:ZHEJIANG UNIV
Artificial cornea optical center and its preparation method, artificial cornea
ActiveCN106491243BImprove antibacterial propertiesImprove adhesionEye implantsCalcium in biologyCell adhesion
The invention relates to the prosthesis material field, and provides a Keratoprosthesis optical central part and a preparation method thereof, and a keratoprosthesis; the Keratoprosthesis optical central part is a Keratoprosthesis optical central film; the surface of the Keratoprosthesis optical central film and a betaine derivative can form active controllable free radical polymerization, wherein the active controllable free radical polymerization is reversible-addition fracture chain transfer free radical polymerization. The Keratoprosthesis optical central part uses an active controllable free radical polymerization method to modify the betaine derivative monomer onto the surface of the Keratoprosthesis optical central film; the modified Keratoprosthesis optical central film is excellent in biology compatibility, anti-calcareous deposition, anti-bacterial and anti-cell adhesiveness performances, thus effectively solving the transparency dropping problems caused by optical central area back and forth propagation films after the Keratoprosthesis is implanted.
Owner:SHENZHEN UNIV
Stent for keratoprosthesis and preparation method thereof
ActiveCN113117146AEasy dischargeReduce forward movementTissue regenerationProsthesisCell-Extracellular MatrixUmbilical cord
The invention provides a stent for keratoprosthesis and a preparation method thereof. The stent comprises: decalcified and decellularized cancellous bone matrix slices->dipping and sticking nanoscale extracellular matrixes (ECM) derived from the cartilage, the umbilical cord and other sources inside and outside the stent->compound autologous mesenchymal stem cells (bone mesenchymal stem cells, adipose-derived mesenchymal stem cells, etc.). After culture, the survived keratoprosthesis stent is placed between layers, on the anterior surface, on the conjunctiva or under the mucosa of the cornea, in order to be used for replacing bones, cartilages or tooth bones in an keratoprosthesis operation, and to be used as a stent / reinforcement material of the keratoprosthesis. According to the invention, the stent for the keratoprosthesis has a microenvironment which is beneficial to in-vitro and in-vivo growth of cells through adsorption and induction, can promote mesenchymal stem cells to be differentiated into cartilaginous tissues and osteogenic tissues in vivo, thus being convenient to fix the keratoprosthesis and improve the in-situ rate of the keratoprosthesis.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL
a simulated eye
Owner:THE EYE HOSPITAL OF WENZHOU MEDICAL UNIV
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