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77 results about "Corneal implants" patented technology
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Corneal implants are small lenses or other refractive devices inserted into the eyes to correct vision problems in humans. Conditions corrected by corneal implants include myopia, hyperopia, and presbyopia.
Coatings on ophthalmic lenses
This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of terminal functionalized surfactants to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
Owner:BAUSCH & LOMB INC
Corneal implant and method of manufacture
Prosthetic implants designed to be implanted in the cornea for modifying the cornea curvature and altering the corneal refractive power for correcting myopia, and myopia with astigmatism, such implants formed of a micro-porous hydrogel material.
Owner:REVISION OPTICS
Corneal implant injector assembly and methods of use
InactiveUS20060235430A1Simple methodImproved implant storageEye implantsEye treatmentCorneal implantsBiomedical engineering
A corneal implant injector assembly includes a barrel, a plunger, and an injector tip with a channel having a size and orientation adapted to store and deliver a corneal implant. The corneal implant is preferably stored in the channel in a contracted state. The plunger has an implant engagement tip for engaging and moving the implant within the channel and to deploy the implant. In some embodiments, the injector tip is selectively detachable from the remaining portion of the injector assembly.
Owner:REVISION OPTICS
Artificial corneal implant
A material that can be applied as implants designed to artificially replace or augment the cornea, such as an artificial cornea, corneal onlay, or corneal inlay (intrastromal lens) is provided. The artificial corneal implant has a double network hydrogel with a first network interpenetrated with a second network. The first network and the second network are based on biocompatible polymers. At least one of the network polymers is based on a hydrophilic polymer. The artificial cornea or implant has epithelialization promoting biomolecules that are covalently linked to the surface of the double network hydrogel using an azide-active-ester chemical linker. Corneal epithelial cells or cornea-derived cells are adhered to the biomolecules. The double network has a physiologic diffusion coefficient to allow passage of nutrients to the adhered cells.
Owner:SANTA CLARA UNIVERSITY
Corneal implant for refractive correction
A corneal implant adapted for implantation between layers of a cornea to focus an image on a retina of an eye includes an inlay, an outer perimeter, and a clear central region capable of refracting light to compensate for a refractive error of an eye. The inlay also has an annular opaque region comprising a plurality of holes or otherwise being adapted to transport nutrients. The annular opaque region extends from the outer circumference of the inlay to the clear central portion. The opaque region extends over a minority of the surface area of the implant. The anterior and posterior surfaces of the inlay are configured to abut adjacent layers of the cornea.
Owner:ACUFOCUS
Corneal implant and method of manufacture
Prosthetic implants designed to be implanted in the cornea for modifying the cornea curvature and altering the corneal refractive power for correcting myopia, and myopia with astigmatism, such implants formed of a micro-porous hydrogel material.
Owner:REVISION OPTICS
Corneal implants and methods and systems for placement
InactiveUS20060173539A1Good biocompatibilityMinimize size of incisionIntraocular lensMedicineCorneal implants
Owner:SHIUEY YICHIEH
Vision enhancing ophthalmic devices and related methods and compositions
Devices, methods, and compositions for improving vision or treating diseases, disorders or injury of the eye are described. Ophthalmic devices, such as corneal onlays, corneal inlays, and full-thickness corneal implants, are made of a material that is effective in facilitating nerve growth through or over the device. The material may include an amount of collagen greater than 1% (w / w), such as between about 10% (w / w) and about 30% (w / w). The material may include collagen polymers and / or a second biopolymer or water-soluble synthetic polymer cross-linked using EDC / NHS chemistry. The material may additionally comprise a synthetic polymer. The devices are placed into an eye to correct or improve the vision of an individual or to treat a disease, disorder or injury of an eye of an individual.
Owner:NAT RES COUNCIL OF CANADA +3
Corneal implants produced by irradiation of polymer films
The corneal implant of the current invention takes the general form of a thin, transparent, flexible, porous, biocompatible film of suitable polymer material. The implant is sufficiently porous, the porosity being imparted by the film being irradiated to produce tracks and the material in those tracks being subsequently removed through an etching process, to allow the adequate flow of gaseous and tissue fluid components through the film. Specific embodiments of the invention are achieved by the addition of features to the general form. The embodiment applicable to corneal reshaping features a surface relief pattern in the implant. The artificial iris embodiment features an imprinted partly to fully opaque or partially reflective annular iris pattern of selected inner and outer diameters.
Owner:ADVANCED OPTICAL TECH
Corneal implant and uses thereof
A membrane for corneal implant or keratoprosthesis comprising a biological polymer and a polyacrylamide is described. The mixture of both polymers produces a hydrogel that becomes a transparent film or membrane upon drying. The resulting device and tissue engineered implants are useful for biomedical applications of the cornea, such as tissue repair and transplantation.
Owner:OTTAVA HEALTH RES INST (CA) +1
Corneal implant and method of manufacture
Prosthetic implants designed to be implanted in the cornea for modifying the cornea curvature and altering the corneal refractive power for correcting myopia, and myopia with astigmatism, such implants formed of a micro-porous hydrogel material.
Owner:REVISION OPTICS
Artificial cornea
The present invention provides an artificial corneal implant having an optically clear central core and a porous, hydrophilic, biocompatible skirt peripheral to the central core. In one embodiment, the central core is made of an interpenetrating double network hydrogel and the skirt is made of poly(2-hydroxyethyl acrylate) (PHEA). In another embodiment, both the central core and the skirt are made of interpenetrating double network hydrogels. The artificial corneal implant may also have an interdiffusion zone in which the skirt component is interpenetrated with the core component, or vice versa. In a preferred embodiment, biomolecules are linked to the skirt, central core or both. These biomolecules may be any type of biomolecule, but are preferably biomolecules that support epithelial and / or fibroblast cell survival and growth. Preferably, the biomolecules are linked in a spatially selective manner. The present invention also provides a method of making an artificial corneal implant using photolithography.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
Instruments and methods for implanting corneal implant via extra-and intra-cameral routes
InactiveUS20090043242A1Enhance shunt engagementIncrease engagementEar treatmentEye surgeryFlow diverterCorneal implants
A method of implanting a transcorneal shunt into a cornea, the shunt having a head and a foot, each having a hole therein, the method including the operations of engaging an insertion tool with a foot hole of the shunt; making an entry incision in the cornea; inserting the shunt, while still engaged with the insertion tool, through the entry incision; making an implant incision in the cornea; inserting the head of the shunt through the implant incision to position and seat the shunt; and releasing the shunt from the insertion tool.
Owner:BECTON DICKINSON & CO
Ophthalmic Device and Related Methods and Compositions
Devices, methods, and compositions for improving vision or treating diseases, disorders or injury of the eye are described. Ophthalmic devices, such as corneal onlays, corneal inlays, and full-thickness corneal implants, are made of a material that is effective in facilitating nerve growth through or over the device. The material may include an amount of collagen greater than 1% (w / w), such as between about 10% (w / w) and about 30% (w / w). The material may include collagen polymers and / or a second biopolymer or water-soluble synthetic polymer cross-linked using EDC / NHS chemistry. The material may additionally comprise a synthetic polymer. The devices are placed into an eye to correct or improve the vision of an individual or to treat a disease, disorder or injury of an eye of an individual.
Owner:OTTAWA HOSPITAL RES INST +2
Corneal inlay design and methods of correcting vision
Methods of designing corneal implants, such as inlays, to compensate for a corneal response, such as epithelial remodeling of the epithelial layer, to the presence of the implant. Additionally, methods of performing alternative corneal vision correction procedures to compensate for an epithelial response to the procedure. Methods of compensating for a corneal response when performing a vision correction procedure to create a center near region of the cornea for near vision while providing distance vision peripheral to the central near zone.
Owner:RVO 2 0 INC D B A OPTICS MEDICAL
Ophthalmic lens, systems and methods having at least one rotationally asymmetric diffractive structure
ActiveUS8894204B2Improve eyesightReduce sensitivitySpectales/gogglesEye diagnosticsCorneal implantsLens plate
Owner:JOHNSON & JOHNSON SURGICAL VISION INC
Insertion system for corneal implants
InactiveUS8162953B2Small sizeDesired locationEye implantsEye treatmentCorneal implantsSurface tension
Provided therein are apparatuses, systems and methods for storing and retrieving a corneal implant and for delivering the corneal implant in or on the cornea. In an embodiment, a insertion system comprises an inserter for delivering a corneal implant to a desired location in or on the cornea. The inserter has a holding space at its distal end for holding a corneal implant therein. A solution may substantially fill the holding space with the corneal implant to keep the implant hydrated and to hold the implant in the holding space by the surface tension of the solution. The corneal implant may be preloaded in the holding space of the inserter and stored in a storage container filled with storage fluid, e.g., saline, until use. To deliver the corneal implant, the inserter is positioned at the desired location, and the corneal implant released from the holding space of the inserter.
Owner:REVISION OPTICS
Ophthalmic lens, systems and methods with angular varying phase delay
ActiveUS20110317124A1Improve eyesightImprove performanceSpectales/gogglesComputer-aided planning/modellingIntraocular lensCorneal implants
Owner:AMO GRONINGEN
Corneal Implant Storage and Delivery Devices
Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants.
Owner:REVISION OPTICS
Corneal implant storage and delivery devices
Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants.
Owner:REVISION OPTICS
Corneal inlay design and methods of correcting vision
Owner:REVISION OPTICS
Collagen mimetic peptide
ActiveUS20180111979A1Higher enzymatic stabilityPromote cell proliferationConnective tissue peptidesEye implantsCell freeCorneal implants
This disclosure relates to a novel Collagen Mimetic Peptide; a multi-arm conjugate comprising said peptide that mimics the higher order triple helical self-assembly of a collagen; a hydrogel comprising said Collagen Mimetic Peptide, optionally comprising collagen and optionally comprising a chemically modified surface; a corneal implant based on said hydrogel / modified hydrogel comprising a transparent central portion formed by an interpenetrating network comprising one or more additional biocompatible polymers wherein the central portion is adapted to remain cell free to ensure unhindered transmission of light.
Owner:UAB FERENTIS
Suturable Hybrid Superporous Hydrogel Keratoprosthesis for Cornea
The present invention features a hybrid superporous hydrogel scaffold for cornea regeneration and a method for producing the same. The hybrid hydrogel is composed of a superporous poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(methyl methacrylate) (PMMA) copolymer mixed with collagen. The hybrid scaffold can be used as a suturable hybrid corneal implant or keratoprosthesis.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Corneal implant and method of manufacture
Owner:REVISION OPTICS
Corneal cover or corneal implant and contact lens and method thereof
A corneal cover or corneal implant to be placed within or onto the surface of the cornea is made of bony fish scales and a contact lens is made of bony fish scales.
Owner:BODY ORGAN BIOMEDICAL CORP
Suturable hybrid superporous hydrogel keratoprosthesis for cornea
InactiveUS20160144069A1Eye implantsPharmaceutical delivery mechanismProsthesisPoly(methyl methacrylate)
The present invention features a superporous hydrogel scaffold for corneal regeneration or replacement and a method for producing the same. The superporous hydrogel is composed of a poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(methyl methacrylate) (PMMA) copolymer mixed with collagen. The scaffold can be used as a suturable hybrid corneal implant or keratoprosthesis.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS
Building stratified biomimetic tissues and organs using crosslinked ultrashort peptide hydrogel membranes
InactiveUS20150320908A1Facilitate conjugationReduce the amount requiredBiocideCell culture supports/coatingCross-linkCorneal implants
The present invention relates to hydrogel membranes comprising a hydrogel, said hydrogel comprising a plurality of tetramer amphiphilic peptides and / or peptoids capable of self-assembling into three-dimensional macromolecular nanofibrous networks, which entrap water and form said hydrogels, wherein at least a portion of said plurality of tetramer amphiphilic peptides and / or peptoids is chemically cross-linked. The present invention further relates to stratisfied biostructures and devices comprising at least two hydrogel membranes of the invention, which can be used e.g. to rebuild human skin and for tissue engineering of organs and tissues. The present invention further relates to corneal implants and devices comprising a hydrogel membrane of the invention.
Owner:AGENCY FOR SCI TECH & RES
Corneal implant and method for correction of impaired vision in the human eye
Corneal implant for introduction into the visual centre (Z) of the cornea of the human eye for the purpose of rectifying impaired vision, in particular presbyopia, or presbyopia in combination with hypermetropia or myopia. To make available a corneal implant which is suitable for use in the visual centre (Z) of the human eye and can be used to correct presbyopia on its own or in combination with hypermetropia or myopia, it is provided that the effective thickness (d) of the corneal implant (2), measured in the direction of the optic axis (5) of the eye, is more than 50[mu]m and the maximum width (b), measured in a plane perpendicular to the direction of thickness, is less than l mm, the corneal implant (2) having no imaging function in relation to the human eye.
Owner:阿尔贝特·达克瑟尔
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