This invention is directed to compounds and compositions which are designed for use in light adjustable ophthalmic devices, such as intraocular implants,
intraocular lenses, phakic
intraocular lenses, contact lenses,
orthokeratology lenses, rigid gas permeable lenses, corneal inlays, corneal outlays, or corneal inserts. The inventive compositions are produced from reactive
monomer mixtures which when polymerized form polymers or polymeric networks having editable refractive indices. Such inventive compositions when exposed to light of certain wavelengths undergo intramolecular
cycloaddition reactions thereby changing the
refractive index in the irradiated regions. When used in ophthalmic devices, the inventive compositions enable post-manufacturing and / or post-operative adjustments to the
optics of the devices by spatially modifying the
refractive index. For example, the vision of a patient with an
intraocular lens made of the inventive compositions can be fine-tuned after implantation and healing by a
light treatment of the
intraocular lens.