38 results about "Ocular structure" patented technology

A corneal inlay protects ocular structures from harmful wavelengths of light while maintaining acceptable color cosmetics, color perception, overall light transmission, photopic vision, scotopic vision, color vision, and / or cirdadian rhythms. The corneal inlay can also include a pinhole effect to increase depth of focus. In some embodiments, the corneal inlay can also correct refractive errors including, but not limited to, higher order aberration, lower order aberration, myopia, hyperopia, astigmatism, and / or presbyopia.

Embodiments provide method and systems for determining or measuring objective eye alignment in an external-coordinate system so as to define a reference axis. Additional embodiments provide a method and system of aligning an objectively determined reference axis of the eye in a selected relationship to a therapeutic axis of an ophthalmic therapeutic apparatus and / or a diagnostic axis of an ophthalmic diagnostic apparatus. Embodiments provide a method and system for planning an ophthalmic treatment procedure based on objective eye alignment in an external-coordinate system so as to define a reference axis of an eye to be treated. The reference axis may be used to position a therapeutic energy component, for example, an orthovoltage X-ray treatment device, e.g., positioned to provide treatment to tissue on the retina, such as the macula.

An intraocular lens assembly (70) including a lens assembly comprising an interface element adapted for attachment to an ocular structure, the lens assembly comprising a tensing element (76) adapted to expand and contract relative to the lens assembly and apply a tensing force on the ocular structure directed towards an inner volume of the lens assembly.

Embodiments provide method and systems for determining or measuring objective eye alignment in an external-coordinate system so as to define a reference axis. Additional embodiments provide a method and system of aligning an objectively determined reference axis of the eye in a selected relationship to a therapeutic axis of an ophthalmic therapeutic apparatus and / or a diagnostic axis of an ophthalmic diagnostic apparatus. Embodiments provide a method and system for planning an ophthalmic treatment procedure based on objective eye alignment in an external-coordinate system so as to define a reference axis of an eye to be treated. The reference axis may be used to position a therapeutic energy component, for example, an orthovoltage X-ray treatment device, e.g., positioned to provide treatment to tissue on the retina, such as the macula.

Ocular solutions containing at least one macrolide antibiotic and / or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial and antifungal effects. In one embodiment, the solution is administered intraocularly after cataract surgery before insertion of a replacement intraocular lens, resulting in reduced posterior capsular opacification which may eliminate the need for a subsequent surgery. The solution may be one that is invasively administered, for example, an irrigation or volume replacement solution containing at least one macrolide antibiotic such as tacrolimus, sirolimus, everolimus, cyclosporine, and ascomycin, or mycophenolic acid. The solution may be one that is non-invasively or topically administered in the form of drops, ointments, gels, creams, etc. and may include eye lubricants and contact lens solutions. The solution may contain a supratherapeutic concentration of agent(s) so that a therapeutic concentration of a topically administered solution accumulates in a diseased ocular structure sufficient to treat the disease.

A corneal inlay protects ocular structures from harmful wavelengths of light while maintaining acceptable color cosmetics, color perception, overall light transmission, photopic vision, scotopic vision, color vision, and / or cirdadian rhythms. The corneal inlay can also include a pinhole effect to increase depth of focus. In some embodiments, the corneal inlay can also correct refractive errors including, but not limited to, higher order aberration, lower order aberration, myopia, hyperopia, astigmatism, and / or presbyopia.

An accommodating intraocular lens (AIOL) assembly (10) including an optics assembly (12) including an inflatable member (14), and characterized by an extra-capsular-bag interface structure (16) for interfacing with ocular structure of an eye external to a capsular bag for implanting the AIOL (10) outside the capsular bag, the extra-capsular-bag interface structure (16) including a less-rigid portion (18) and a more-rigid portion (20) that define a volume therebetween which is at least partially filled with a fluid (22) and which is in fluid communication with the inflatable member (14) via at least one conduit (24), and wherein the less-rigid portion (18) is responsive to movement of the ocular structure to apply a pumping force on the fluid (22) to cause the fluid (22) to flow via the at least one conduit (24) to the inflatable member (14) so as to change the optical power of the optics assembly (12).

Ocular solutions containing at least one macrolide antibiotic and / or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial, and antifungal effects. In one embodiment, the solution is administered intraocularly after cataract surgery before insertion of a replacement intraocular lens, resulting in reduced posterior capsular opacification which may eliminate the need for a subsequent surgery. The solution may be one that is invasively administered, for example, an irrigation or volume replacement solution containing at least one macrolide antibiotic such as tacrolimus, sirolimus, everolimus, cyclosporine, and ascomycin, or mycophenolic acid. The solution may be one that is non-invasively or topically administered in the form of drops, ointments, gels, creams, etc. and may include eye lubricants and contact lens solutions. The solution may contain a supratherapeutic concentration of agent(s) so that a therapeutic concentration of a topically administered solution accumulates in a diseased ocular structure sufficient to treat the disease. The agent(s) may be formulated with polymers or other components for extended or slow release to provide a substantially constant concentration over the course of treatment.

An intraocular lens assembly (70) including a lens assembly comprising an interface element adapted for attachment to an ocular structure, the lens assembly comprising a tensing element (76) adapted to expand and contract relative to the lens assembly and apply a tensing force on the ocular structure directed towards an inner volume of the lens assembly.

A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

Disclosed are systems, devices and methods for performing simulations using a multi-component Finite Element Model (FEM) of ocular structures involved in ocular accommodation.

A method of staining an ocular structure, the structure being a human or other mammalian eye or portion thereof, the method comprising staining the ocular structure with either indigotindisulfonate, Patent Blue V, Sulphan Blue, tolonium chloride, or Evans Blue. Ocular structures of particular interest are the anterior lens capsule and the vitreo-retinal interface.

Ocular solutions containing at least one macrolide antibiotic and / or mycophenolic acid provide anti-inflammatory, anti-cell proliferation, anti-cell migration, anti-angiogenesis, antimicrobial, and antifungal effects. In one embodiment, the solution is administered intraocularly after cataract surgery before insertion of a replacement intraocular lens, resulting in reduced posterior capsular opacification which may eliminate the need for a subsequent surgery. The solution may be one that is invasively administered, for example, an irrigation or volume replacement solution containing at least one macrolide antibiotic such as tacrolimus, sirolimus, everolimus, cyclosporine, and ascomycin, or mycophenolic acid. The solution may be one that is non-invasively or topically administered in the form of drops, ointments, gels, creams, etc. and may include eye lubricants and contact lens solutions. The solution may contain a supratherapeutic concentration of agent(s) so that a therapeutic concentration of a topically administered solution accumulates in a diseased ocular structure sufficient to treat the disease. The agent(s) may be formulated with polymers or other components for extended or slow release to provide a substantially constant concentration over the course of treatment.

The present invention relates to oxygenated ophthalmic topical compositions and methods of administering oxygenated ophthalmic topical compositions. The present invention also encompasses methods for making and administering the oxygenated ophthalmic topical compositions for use in treating or ameliorating pathologic conditions, complications, diseases and symptoms related to hypoxia of the anterior eye structure, including corneal neovascularization (CNV), edema, abrasions, infections, infiltrates, dry eye syndrome, contact lens intolerance; and redness, blurred vision, discomfort, foreign body sensation, photophobia, and irritation.

An accommodating intraocular lens (AIOL) assembly (10) including an optics assembly (12) including an inflatable member (14), and characterised by an extra-capsular-bag interface structure (16) for interfacing with ocular structure of an eye external to a capsular bag for implanting the AIOL (10) outside the capsular bag, the extra-capsular-bag interface structure (16) including a less-rigid portion (18) and a more-rigid portion (20) that define a volume therebetween which is at least partially filled with a fluid (22) and which is in fluid communication with the inflatable member (14) via at least one conduit (24), and wherein the less-rigid portion (18) is responsive to movement of the ocular structure to apply a pumping force on the fluid (22) to cause the fluid (22) to flow via the at least one conduit (24) to the inflatable member (14) so as to change the optical power of the optics assembly (12).

An intraocular clip including first and second hook members extending generally coplanarly in opposite directions from a spine, the spine being formed with an attachment member attachable to ocular structure.

A portable orthovoltage radiotherapy system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system.

Axial distances between ocular structures can be measured by focusing an optical unit on focus planes corresponding to the ocular structures and using the distance between focus planes to determine the distance between the ocular structures. The method is particularly useful during eye surgery, e.g., cataract surgery, where the distance between ocular structures, particularly an aphakic pupil, can be used to more accurately predict the effective lens position for an intraocular lens.

An apparatus for motion compensated modelling of a parameter of an eye, comprising: a first measuring means for measuring a plurality of position parameters of the eye with respect to an optical reference coordinate system of the apparatus; a second measuring means for measuring an interference signal at a plurality of optical reference coordinates, wherein the measurement of the plurality of position parameters and measurement of the interference signal are time synchronised; means for correcting the interference signal to account for a displacements of a parameter of the plurality of position parameters; and means for modelling the eye parameter based at least in part on the corrected interference signal.

Disclosed are systems, devices and methods for a modeling of ocular structures involved in ocular accommodation and use of a multi-component Finite Element Model (FEM).

An ophthalmological measuring system for determining distances and / or for tomographic imaging of ocular structures, based on an OCT method. The measuring system includes a light source with a spectral centroid (λ), an interferometric measuring device, a scanner system, which in addition to the lateral deflection of the sample beam also has axial modulations with a frequency (f) in the sample arm, and a control and evaluation unit. The scanner performs a lateral, two-dimensional deflection of the sample beam with the aid of one or even two separate mirror elements and can in particular have axial modulation amplitudes zM>>λ / 2. The system can also be used for scanner systems in other fields that use an OCT method, in particular a swept-source OCT method.

An automatic system and method for non-invasive imaging and identification of specific ocular structures of the eye and adnexa tissues by synchronous segmentation of visual and infrared images; that can produce spatial temperature profiles within each segmented area of the eye and adnexa; that can track eye and head movement and eye-blinks during the period of measurement to remove artefacts and maintain synchronicity; that can track ocular surface and eye adnexa temperature profiles over time; that can assist in diagnosis of eye disease; that can produce diagnostic indicators for ocular disease diagnosis and study of the eye. The system comprises infrared and visible light cameras for imaging the ocular structures, and a digital signal processing unit for processing the acquired infrared and visible images to output segmentations of the images for identification of different areas of the eye surface, including pupil, cornea, conjunctiva, and eyelids. The system further captures synchronous infrared and visible images from each segmented area of the ocular surface over the time of measurement. A digital signal processing unit processes and analyzes the infrared and visible images to generate descriptive outputs on temporal and spatial changes in the infrared and visible images over the time of measurement, as well as produce diagnostic indicators for ocular disease diagnosis and study of the eye.

The disclosure provides systems, devices, and associated methods for mitigating traumatic brain injury, injury to an ocular structure, or injury to the inner ear of a subject by applying pressure to one or more neck veins before and during an injurious event.

An apparatus has an image capture sensor which captures a reference image of a retro-illuminated unstained capsule of an eye. After the ocular structure has been stained with a dye for an ophthalmic surgical procedure a second image is captured as a measurement image via the image capture sensor. An evaluation module compares the reference image and the measurement image taken after the staining of the ocular structure. The evaluation module from the comparison of the reference and measurement images then determines the local light attenuation by the introduced dye. The staining of the eye can also be determined by only imaging a stained ocular structure of an eye and evaluating the images on the basis of predetermined acceptance values.

An imaging system for an optical element, the imaging system comprising means for illuminating a targeted optical element with at least one incident light beam and means for directing at least two light beams returning from at least one surface of the illuminated optical element onto a detector; the detector adapted to measure relative light characteristics of the at least two returning light beams and to calculate at least one parameter of the optical element using the measured characteristics of the at least two returning light beams.

An intraocular clip including first and second hook members extending generally coplanarly in opposite directions from a spine, the spine being formed with an attachment member attachable to ocular structure.

Apparatus, systems and techniques for capturing, processing and generating digital ophthalmic images using conventional ophthalmic lenses. Certain embodiments processor implemented gesture-based control methods that provide for an eye care specialist to use a gesture-based imaging trigger to capture images of selected ocular structures through a traditional ophthalmic lens.

This invention, a Purkinjenator™ optical system, is an eye-tracker and methodology for tracking Purkinje reflection images from a human eye in real-time, which allows for the XYZ position and tip / tilt of structures inside the eye to be determined in real-time. When used in combination with programmable groups of IR LED light sources, unique patterns of Purkinje reflections from internal surfaces (and corneal surfaces) can be identified. Thus, XYZ positioning and tip / tilt of internal structures can be accurately and rapidly determined. An Optical Coherence Tomography (OCT) optical system can be combined with the Purkinjenator™ optical system to provide Z-axis distance information.

An ocular structure for observation apparatus includes a first member, a second member and a main body. The first member includes at least one slot and a plurality of first limiting mechanisms. The second member includes at least one slider extending into the slot and a plurality of second limiting mechanisms. The main body includes an ocular lens unit, wherein the first member and the second member are mounted on the main body. The slider is moved in the slot when the first member and the second member are in relative rotation, and the first limiting mechanisms directly or indirectly match the second limiting mechanisms to position the first member with respect to the second member.

Disclosed are systems, devices and methods for a modeling of ocular structures involved in ocular accommodation and use of a multi-component Finite Element Model (FEM).