The invention discloses a transmission device and an air conditioner comprising the transmission device. The transmission device comprises a first connecting rod, a second connecting rod, air guiding blades and a horizontal transmission mechanism. A second sliding part of the second connecting rod is slidably connected with a first sliding part of the first connecting rod, and the horizontal transmission mechanism drives the air guiding blades connected to the second connecting rod to perform lateral deflection through the first connecting rod. When the air guiding blades perform longitudinal movement up and down in air outlet, the air guiding blades are adjusted to the appropriate position according to a running mode of the air conditioner so as to overcome influence on wind direction adjustment caused by adjustment of density difference between air flow and indoor air. Simultaneously, when left and right swing is not needed, the air guiding blades can all descend into an air conditioner base below the air outlet to be hidden; simultaneously, when swing is not needed, the air guiding blades can move downwards until the air guiding blades are hidden; the air conditioner is intelligently controlled to supply air in a three-dimensional mode through the transmission device, manual poking is not needed, and accidents in the operation process are avoided.