The invention discloses an orthokeratology lens cleaning instrument, which comprises a base, a plastic cover fixed on the base, a lithium battery fixed on the upper end of the plastic cover, an operation interface fixed on the plastic cover, Two micro-vacuum pumps on the base, cleaning fluid on the plastic cover, magnetic module on the plastic cover, two stepping motors on the magnetic module, two stepping motors respectively The two orthokeratology lens clips on the top, the two cleaning nozzles on the side wall of the plastic case, the sewage tank that is movable on the base, the sewage baffle fixed on the sewage tank, and the sewage baffle on the base. Fixtures for securing it.