31 results about "Lacrimal gland" patented technology

A method and preparation for the stimulation of tear secretion in a subject in need of such treatment is disclosed. The method comprises administering to the ocular surfaces of the subject a purinergic receptor agonist such as uridine 5′-triphosphate [UTP], dinucleotides, cytidine 5′-triphosphate [CTP], adenosine 5′-triphosphate [ATP], or their therapeutically useful analogs and derivatives, in an amount effective to stimulate tear fluid secretion and enhance drainage of the lacrimal system. Pharmaceutical formulations and methods of making the same are also disclosed. Methods of administering the same would include: topical administration via a liquid, gel, cream, or as part of a contact lens or selective release membrane; or systemic administration via nasal drops or spray, inhalation by nebulizer or other device, oral form (liquid or pill), injectable, intra-operative instillation or suppository form.

The present invention provides an opthalmologic apparatus that can noninvasively measure the state of the lacrimal layer formed on the cornea surface and that can quantitatively measure the state of the lacrimal layer without utilizing a reflection image from the retina.

The opthalmologic apparatus according to the present invention comprises an optical projection system for projecting light of a specified pattern onto a cornea surface, and an imaging device for photographing a reflection image of the projected light from the cornea surface. An operating unit calculates the degree of distortion of the reflection image on the basis of the density value distribution of the image photographed by the imaging device. The operating unit can determine the state of the lacrimal layer using the calculated degree of distortion.

Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.

The invention discloses herbal shampoo and bath foam for an infant. The herbal shampoo and bath foam is prepared from components in percentage by weight as follows: 0.6%-26% of plant extracts, 1%-10% of decyl glucoside, 1%-10% of cocamidopropyl betaine, 1%-15% of sodium cocoamphoacetate, 0.1%-5% of sodium lauroyl glutamate, 0.1%-1% of methyl glucose dioleate, 0.4%-1% of 3-[2-(ethylhexyl)oxyl]-1,2-propandiol, 0.4%-1% of phenoxyethanol, 0.01%-0.5% of EDTA-2Na, 0.1%-1% of erythritol and the balance of water, wherein the plant extracts comprise a sophora flavescens root extract, a honeysuckle flower extract, a Chrysanthellum indicum extract, wild chrysanthemum extract, a rheum palmatum root extract and a tea extract. Meanwhile, the invention discloses a preparation method of the herbal shampoo and bath foam for the infant. The herbal shampoo and bath foam prepared with the method for the infants can clean and moisturize skin and hair of the infant simultaneously without irritating lacrimal gland and skin of the infant, and has the effects of soothing and moisturizing the skin of the infant and protecting sebum of the skin.

A biomaterial mass is inserted through a punctum into a canaliculus in the lacrimal outflow system with a syringe. The mass has an outer cross section that is less than the inner cross section of the canaliculus. The mass absorbs liquid to swell to form a lacrimal filler or sealing mechanism. The lacrimal filler has an external cross section that conforms to the internal cross section of the canaliculus and a soft outer surface relative to the surrounding tissues to prevent erosion of the canaliculus lining. The lacrimal filler forms an occlusion that prevents the outflow of liquid through the lacrimal outflow system to retain tears within the eye to maintain eye lubrication and wetness. The mass and syringe are provided in kit with a rubber stopper and, optionally, a punctal dilator, an injecting catheter, and an enzyme for dissolving or degrading the lacrimal filler at a later time.

Disclosed herein is system for inserting lacrimal stents utilizing a rigid tapered probe and a flexible, blunt-tipped probe, wherein both probes provide a channel for directing a guidewire. The guidewire assists in efficiently positioning lacrimal stents, while minimizing possible injury to the lacrimal apparatus structures.

The invention relates to a keratoconjunctivitis sicca preventing and treating eye drop and a preparation and application method thereof. The keratoconjunctivitis sicca preventing and treating eye drop is composed of cyoloalliin, anthocyanin, dextranum, hydroxypropyl methyl cellulose, sodium chloride, potassium chloride, sodium borate, pH regulator and purified water. During application, the keratoconjunctivitis sicca preventing and treating eye drop can supplement water for eyes, form protective films on the surfaces of eyes and reduce water evaporation to effective relieve the symptoms caused by keratoconjunctivitis sicca such as dry eyes, and meanwhile, can stimulate secretion of lacrimal glands and increase the number of times of blinking; the cyoloalliin can inhibit secretion of inflammatory factors to release the clinical symptom of dry eyes and meanwhile fundamentally cure the keratoconjunctivitis sicca; besides, the keratoconjunctivitis sicca preventing and treating eye drop is free from preservatives, safe, non-irritative to eyes, high in long-term stability and applicable to wide application of prevention and treatment of various kinds of keratoconjunctivitis sicca.

A lacrimal stent for intraluminal drainage of a mammal is provided having an elongated tubular member configured to be inserted into at least a portion of the lacrimal drainage structures of the mammal. The elongated tubular member includes an exterior sidewall surface and an interior lumen. The lacrimal stent further includes at least one axial port extending through the exterior sidewall surface to the lumen of the elongated tubular member. The axial port is configured to permit fluidic flow therethrough of the tears of the mammal into the lumen for the purpose of intraluminal drainage.

The invention provides an eye drop collector. The eye drop collector comprises an eye drop gun, a liquid taking device and an eye drop storage tube, wherein the interior of the eye drop gun is detachably connected with the liquid taking device, one end of the liquid taking device is detachably connected with the eye drop storage tube, and the eye drop storage tube is arranged at the tail of the eye drop gun. The eye drop collector has the advantages that eye drops of the human body can be rapidly, accurately and safely collected, the liquid taking device is fixed through the eye drop gun to ensure that a user can accurately puncture a suction needle into the lacrimal gland of the eye of the human body, and therefore the problems that the eye drops of a doctor are difficult to collect, theoperation is inconvenient, and consequently the surgical risk is increased are solved.

The invention relates to a fast shredding device. A handle is arranged on the upper end of a round metal wire net through a support frame. The fast shredding device also comprises a box body matched with the diameter of the round metal wire net, and the round metal wire net is an alloy steel wire net. The fast shredding device provided by the invention has the advantages that the vegetable shredding operation can be completed through once cutting, the shredding does not need to be completed by a kitchen knife for many times, the efficiency is improved, shredded shreds have the same size and are uniform and attractive, in addition, lacrimal gland stimulation caused by juice of spicy vegetables can be avoided during the spicy vegetable cutting, the occurrence of condition of tear bursting of people is avoided, the box body is used as a container for containing vegetables during the shredding, cleanness and sanitation are realized, simultaneously, the box body is also used as the container for the cut vegetable shreds, cleanness and sanitation are realized, and the secondary pollution caused by transferring is avoided. The hardness of the alloy steel wire net is high, the deformation prevention in multi-time cutting can be realized, and the service life is prolonged. The fast shredding device also has the advantages that the structure is simple, the use is convenient, the manufacture cost is low, and the fast shredding device is suitable for large-range popularization and application.

The invention relates to the technical field of eye drops, in particular to lanosterol eye drops and a preparation method thereof. The eye drops comprise lanosterol compounds, vitamin A, vitamin E, a traditional Chinese medicine extract and a thickening agent. According to the eye drops, the lanosterol compound is used as a main material, the effect of preventing or assisting in treating cataract is achieved, low-dosage vitamin A and vitamin E are added, vitamin A can increase lacrimal gland secretion and has a good improvement effect on xerophthalmia, vitamin E has an anti-oxidation effect, eyes are protected from being attacked by free radicals, and the thickening agent is added to improve the emulsification dispersity, so that the wetting effect of the eye drops is ensured. In addition, the traditional Chinese medicine extracting solution extracted from various traditional Chinese medicines is added, and the eye drops have the effects of removing nebula and improving eyesight and have good prevention and treatment effects on xerophthalmia, blurred vision, cataract and the like.

The present invention pertains generally to the field of coolants and medical therapy. More particularly, the present invention relates to certain anti-nociceptive agents, such as [((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexanecarbonyl)-amino]-acetic acid isopropyl ester, that are potent and long-acting and selectively cooling for non-keratinized epithelial tissues as compared to keratinized epithelial tissues, and are useful, for example, for the treatment of (e.g., the alleviation of symptoms of; the amelioration of) sensory discomfort of non-keratinized stratified epithelial (NKSE) tissue;and so for treatment of: sensory discomfort of an ocular surface, an eyelid, a margin of an eyelid, an anterior part of an eyeball, a conjunctiva, a lachrymal system, a pre-corneal film, or a cornea, a lining of the oral cavity, an internal portion of the lips, a pharyngeal surface, an esophageal surface, or an anogenital surface; eye discomfort, e.g., caused by extended wear of contact lenses, by eye strain and/or fatigue, by air pollutants, by excessive exposure to the sun, by conjunctivitis, by dry eye syndrome; sensory discomfort associated with oral mucositis; airway (e.g., larynx, trachea, and/or bronchi) tightness, discomfort in the airways (e.g., larynx, trachea, and/or bronchi), choking, cough, and/or dyspnea, e.g., associated with asthma and/or chronic obstructive pulmonary diseases (COPD).

The invention discloses a high-stability PAC1 type receptor specific agonist MPAPO and a preparation method and an application thereof. Compared with wild type PACAP, the agonist MPAPO has the following different points: the 17th changes from wild type methionine to leucine by mutation; the 27th changes from wild type leucine to lysine by mutation; the 28th changes from wild type glycin to lysineby mutation; and one methionine is added at the N end. The differences lead the MPAPO to have higher stability and specific activation activity to a PAC1 type receptor; furthermore the stability is about 30 times higher than that of the wild type PACAP. Experiments prove that the agonist MPAPO can be applied in the preparation of drugs with the following functions: promoting nerve regeneration and repair after nerve injuries, such as promoting corneal neuritogenesis after corneal injuries, promoting corneal epithelial cell repair, improving corneal sensitivity and improving the lacrimal glandsecretion function.