1293 results about "ATP - Adenosine triphosphate" patented technology

Therapeutic methods and compositions useful for the prevention and / or treatment of cellular membrane damage leading to or resulting from peroxidation of the cellular membrane and a breakdown of the barrier function of the cellular membrane. A therapeutic composition includes a combination of a membrane sealing sealing surfactant and a cofactor treatment consisting of an antioxidant and a cellular energy store. To affect this goal, the permeability of damaged cellular membranes is reestablished by the membrane sealing surfactant, effectively “sealing” the injured membranes. To facilitate rapid tissue recovery, cellular energy levels can be reestablished through addition of a cellular energy source such as, for example, MgCl2-ATP which, serves a further dual benefit of improving the cellular ion balance. Addition of an antioxidant eliminates the generation of Reactive Oxygen intermediates and enhances the metabolism of free radicals.

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

A method and apparatus for pre-processing electronic data requests within the EDI subsystem layer and within the order fulfillment application system. An order interceptor, third-party Available To Promise (ATP) interface, pseudo-sales order workbench, and the reject acknowledgment system processes are provided within the order fulfillment application system to accomplish the pre-processing. The order interceptor performs an asynchronous availability check before a sales order is posted. The result of the ATP check is stored in an ESO, and is applied during the posting process with unique user exits. The result of the ATP check is also used to determine key information about the sales order, such as the sales organization, and division and distribution channels. The pre-processor uses business rules to determine if the ESO should be split into multiple documents for requests satisfied across multiple sales areas. The Workbench provides a customer purchase order view of the ESO that looks, feels and behaves like actual order entry screens. The Workbench also displays messages generated from the pre-processor describing why the ESO was held for review. After the condition is corrected the Workbench re-executes the ESO pre-processor. This continues until all messages are corrected or marked reviewed. The supplier can decide to either accept the request, reject the request or accept individual line items.

The present invention provides biological fertilizer compositions that comprise yeast cells that have an enhanced ability to fix atmospheric nitrogen, decompose phosphorus minerals and compounds, decompose potassium minerals and compounds, decompose complex carbon compounds, over produce growth factors, and over produce ATP. The biological fertilizer composition of the invention can replace mineral fertilizers in supplying nitrogen, phosphorus, and potassium to crop plants. Methods of manufacturing the biological fertilizer compositions and methods of uses are also encompassed.