38 results about "Skin incision" patented technology

The present invention provides a therapeutic instrument including a vertebral drilling guide and a bone drilling instrument, the therapeutic instrument being configured as follows. The vertebral drilling guide is a hollow cylindrical shape along a central axis, with a first scoop part opening in a direction perpendicular to the central axis at the leading-end side along the central axis and a second scoop part opening in the opposite direction of the perpendicular direction at the base-end side along the central axis. The bone drilling instrument is rod-shaped, is smoothly curved in the perpendicular direction along a central axis, and when inserted into the vertebral drilling guide along the central axis from the distal end of the second scoop part of the vertebral drilling guide, a leading-end portion thereof protrudes out of an opening in the first scoop part. This makes it possible to provide a safe therapeutic instrument that enables precise drilling of an intended area all the way inside the vertebral body while minimizing skin incision in percutaneous vertebroplasty of fractures and prophylactic reinforcement of the vertebral body with bone cement.

The invention discloses a minimally invasive degradable reduction device for thoracolumbar vertebral fracture, and relates to the technical field of medical instruments. The mounting mechanism is mounted on the outer wall of the connecting rod in a sleeving manner; the pedicle screw is movably inserted into the middle of the top end of the mounting mechanism; an implantation mechanism; through cooperative work of the connecting rod, the mounting mechanism, the pedicle screw and the connecting mechanism, the whole reduction device adapts to minimally invasive approach modes such as percutaneous puncture and can be implanted into the body of a patient through a percutaneous puncture channel, a skin incision of the minimally invasive approach is small, damage to surrounding tissue is greatly reduced, and the reduction effect is good. Due to the layered design of the screw body in the pedicle screw, bone tissue ingrowth is promoted while the supporting strength is kept, and the reduction device is made of degradable materials, can be gradually degraded along with fracture healing after an operation and is metabolized and absorbed by an organism, and does not need to be taken out through a secondary operation, so that physical and mental pain of a patient is relieved; and the medical cost and the potential risk of the secondary operation are also reduced.

The invention discloses a digital intelligent operating room route control software system, and relates to the technical field of medical informatization and intelligent operating rooms. The dynamic sensing mechanism collects five-dimensional data of operation progress, equipment alarm, voice instructions, network loads and operator identities in real time, and the current operation stage (including skin cutting, suturing and emergency intervention) is judged through a state machine engine. An intelligent decision closed-loop mechanism; the intelligent decision closed-loop mechanism detects state change every 200 milliseconds, automatically loads a preset strategy template, optimizes parameters through a genetic algorithm, and issues a flow table rule in real time through the SDN controller to form a'sensing-decision-execution-monitoring 'closed loop. The operation and maintenance efficiency is improved, IT personnel only need to maintain the strategy template library, and the daily intervention demand is reduced by 90%.

The set of inventions relates to medical devices, in particular to surgical retractors and wound retractors for displacing and securing anatomy of a surgical incision in a given position during surgery to provide access to a surgical region of a patient's body. A removable clip for a surgical retractor, made as an L-shaped curved member, includes a base provided with a device for fixation in a surgical retractor and a microsurgical instrument recess, and a pair of teeth for holding an anatomical structure. The toothing is configured as a profiled plate with a working area widening to ensure contact with the anatomical structure, the widening being formed by a raised pad located at least on the inner and / or outer end edge side of the lower end of the plane of the toothing plate. The included angle between each tooth part and the plane of the base is smaller than 90 degrees, and therefore gaps used for passing of microsurgical instruments are formed between the tooth parts. The surgical retractor comprises a frame with a rack carrying a fixed arm and a movable arm, the fixed arm and the movable arm being hingedly connected to a retainer for the detachable clip, where the retainer is configured to receive at least one of the aforementioned detachable clips. A removable clip assembly for a surgical retractor includes at least one central dual tooth removable clip; the at least one peripheral double-tooth detachable clamp is constructed to be capable of accommodating the central double-tooth clamp between the tooth parts of the central double-tooth clamp; and at least one central single-tooth detachable clamp. The use of the invention provides an increased working space and a higher degree of freedom of surgical instrument operation, enabling access to the lateral region of the operated structure during surgery without extending the skin incision.

The invention relates to the field of smart wristbands, and discloses a smart wristband data synchronization method and system for preoperative safety check, which are used for improving the accuracy of preoperative safety check. The method is applied to a system comprising a wrist strap, a ward reader-writer, a transfer reader-writer and an operating room reader-writer, and comprises the steps that the ward reader-writer generates a first synchronization instruction containing patient information and writes the first synchronization instruction into the wrist strap to initialize the wrist strap, the transfer reader-writer reads wrist strap data during transfer, generates a transfer verification record and writes the transfer verification record, and the wrist strap enters a transfer confirmation state; the operating room reader-writer reads data at an entrance to generate an operation checking list, multiple parties check together before skin cutting, and the handheld read-write device writes a confirmation result into the wrist strap to enable the wrist strap to enter an operation ready state to authorize an operation. Through a hierarchical data structure, multi-link verification and an emergency processing mechanism, accurate synchronization and safety of data are ensured, the efficiency and accuracy of preoperative safety check are improved, and operation safety is ensured.

A catheter placement system including a catheter, a needle for creating an insertion site, and a skin nicking device for enlarging the insertion site. A catheter placement device includes the skin nicking device slidably coupled with the needle, where the skin nicking device has one or more blades attached to a frame thereof. Distally displacing the skin nicking device along the needle causes the blade to nick the skin to enlarge the insertion site. A shield of the skin nicking device transitions between a safe configuration encapsulating the blade and a use configuration exposing the blade and the shield may be biased toward the safe configuration. A latch secures the shield in the safe configuration and an actuator releases the latch. A sheath of the skin nicking device includes the needle slidably disposed within a lumen thereof and a sharp tip of the blade embedded within a wall thereof.

The utility model discloses a drainage tube leakage liquid suction mechanism and abdominal drainage tube anti-seepage drainage device. The drainage tube leakage liquid suction mechanism includes: sheath, the side wall is equipped with the longitudinal entry for clamping to the drainage tube, and the lower part is formed with containing cavity and the absorption hole for leading out tissue fluid, the number is at least 1, is equipped with the clamping gap of being set to the drainage tube with its sleeve, is used for absorbing tissue fluid, the seepage liquid suction tube is fixed to the outside of sheath with one end and communicates with the absorption hole, and the other end is connected with the seepage liquid storage bag of connectable negative pressure connection, and the sticking part is used for fixing sheath on the skin incision. The utility model discloses through the cooperation of sheath and absorption pad, can improve the stability of the drainage tube and the patient's body connection, and the exuded tissue fluid is absorbed by absorption pad first and then is sucked by seepage liquid suction tube, can effectively prevent the overflow of exudate, and the replaceable absorption pad is favorable to guarantee its patency, makes the skin incision be in the relatively ventilated dry environment, is favorable to the recovery of illness.

Minimally invasive histotripsy systems and methods are provided. In some embodiments, a minimally invasive histotripsy device is inserted into a patient. The device can be inserted endoscopically through a natural orifice of the patient, or laparoscopically through an incision in the patient's skin. The minimally invasive histotripsy device can be advanced to the target tissue and acoustically coupled to the target tissue before applying histotripsy therapy to the target tissue. In some embodiments, the minimally invasive histotripsy device includes a transducer array with a focal length of approximately 10-40 mm, a diameter of less than 35 mm, and the ability to create a peak negative focal pressure of at least 20 MPa.

FIELD: plastic surgery.SUBSTANCE: under aseptic conditions and endotracheal anesthesia, hydropreparation of the subcutaneous fat tissue is performed with 0.04% ropivacaine solution 60.0 ml with adrenaline 1:100000, a skin incision in the area of the submammary groove of the mammary gland of 3.5–4.0 cm in length is made, the tissues are dissected layer by layer to the fascia of the pectoralis major muscle. A dissection is performed in the Chassignac space to the level of the lower pole of the areola or an incision is made in the skin in the area of the mammary gland along the lower semicircle of the areola, the tissues are perpendicularly dissected layer by layer to the fascia of the pectoralis major muscle. Next, dissection is performed in the Chassignac space to the level of the submammary groove, and the lateral edge of the right pectoralis major muscle is isolated. The retropectoral pocket for the implant is formed using blunt and sharp methods. The lower medial bundle of the pectoralis major muscle is mobilized to the level of 4 o'clock on a conventional clock dial for the right breast and to the level of 8 o'clock on a conventional clock dial for the left breast. Partial vertical myotomy of the free muscle flap is performed. The distal fragments of the pectoralis major muscle are fixed at three points to the posterior surface of the gland with an atraumatic Vikryl 2-0 thread at the level of the nipple-areolar complex. A silicone implant is placed into the formed pocket, and the implant is evenly distributed and centered within it.EFFECT: preventing uncontrolled cranialization of the pectoralis major muscle flaps during vertical myotomy in dual-plane augmentation mammoplasty.1 cl, 2 ex

The invention relates to the technical field of keloid resection, and discloses a minimally invasive surgery device for keloid core resection, which comprises a body, and further comprises an outer sleeve fixedly connected to the front end of the body, the outer sleeve is of a slender hollow structure and is used for being inserted into keloid tissues through a skin tiny incision; the inner cutting tube is coaxially arranged in the outer sleeve and can rotate relative to the outer sleeve, and an annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner cutting tube; according to the minimally invasive surgery device for keloid core excision, the outer sleeve and the inner excision tube are coaxially arranged, and the annular cutting edge used for cutting keloid fibrous tissue is formed at the far end of the inner excision tube, so that the device can enter the keloid through a tiny incision of the skin; on the premise of reducing skin wounds, effective treatment of keloid core tissues is realized, and improvement of postoperative healing effect and appearance recovery are facilitated.

The disclosure relates to methods of treating and / or preventing scarring that would otherwise result from an incision to an area of skin. The methods comprise administering a composition comprising tropoelastin to an area of skin that is to receive an incision and / or after the incision. It is also contemplated that the compositions may reduce scar discoloration. Methods of preventing or reducing keloid re-occurrence are also provided.

The utility model relates to a hip and knee joint cavity perfusion drainage device. The device comprises a drug delivery mechanism and a suction mechanism which are arranged in vitro; the drug feeding mechanism is connected with a drug injection header pipe, the suction mechanism is connected with a drainage header pipe, and the drug injection header pipe and the drainage header pipe enter a human body through a skin incision; the medicine injection header pipe is arranged in a forked mode after entering a human body to form medicine injection branch pipes used for being placed in a hip joint cavity or a knee joint cavity, and medicine injection holes are evenly distributed in the medicine injection branch pipes. The main drainage pipe is arranged in a forked mode after entering the body, and a suction branch pipe used for being placed in a hip joint cavity or a knee joint cavity is formed. According to the utility model, a self-made simple medicine injection drainage tube commonly used in clinic at present can be replaced, so that the local part of an articular cavity is continuously, stably and uniformly dosed, the optimal effect of locally applying antibiotics is achieved, and the stable high-concentration state of the antibiotics is maintained. Meanwhile, skin incisions can be reduced, and the risks of incision infection and reverse infection are avoided.

The invention provides a disposable skin incision stitching instrument, and relates to the field of skin stitching instruments, the disposable skin incision stitching instrument comprises two tensioning sealing pages, the two tensioning sealing pages are fixedly connected with connecting pages, the other ends of the two connecting pages are fixedly connected with adhesive pages, two pull stickers are arranged between the two tensioning sealing pages, and the two pull stickers are fixedly connected with the connecting pages. And the lower side surfaces of the two pull stickers are provided with magic stickers. The multiple inhaul cables are alternately and reversely arranged between the two tensioning covers, so that the centripetal tension of the multiple crossed inhaul cables can drive tissues on the two sides of a skin incision to be naturally closed, needle and thread puncture or instrument clamping of the wound is not needed, and secondary damage to the wound is avoided; the two opposite sliding rods are driven to move synchronously by the two tensioning sealing pages close to each other, so that disinfectant in the liquid storage pipe is extruded and discharged by the built-in piston and then is uniformly sprayed to an incision and a surrounding area through the porous cavity, action linkage between suturing and disinfection is achieved, and it is ensured that disinfection and wound closing are completed synchronously.

The present disclosure relates generally to a medical / surgical cutting device, and more particularly to a medical / surgical cutting device that is structured and configured to move between non-cutting and cutting configurations / positions, capture soft tissue and actuate a blade to the cutting configuration / position outside of a skin incision to transect and obtain a soft tissue graft.

The utility model discloses a tubular tool bit for skin micro-punching, which comprises a tool body in a tubular structure; wherein first tangent plane structures are arranged at two opposite positions at the outer end of the cutter body, so that two blade parts are formed on the cutter body, the two blade parts are connected end to end to form an annular blade, and the joint of the two blade parts is sharp. According to the utility model, an incision with two narrow ends and a wide middle part can be cut on the skin, so that the difficulty of drawing and closing the skin incision is reduced, and the contraction effect of the skin is guaranteed while the suture effect of the incision is improved.

The present invention is a therapeutic instrument including a vertebral body perforation guide and a vertebral body processing tool, and is configured as follows. The vertebral body perforation guide is a hollow cylinder running along a central axis, and comprises a distal end spatula portion, an intermediate portion, and a terminus portion, in the stated order from the proximal side along the central axis. The distal end spatula portion opens in a direction perpendicular to the central axis. The terminus portion has an opening in a direction perpendicular to the central axis. The inner diameter of the intermediate portion in the up-down direction is greater than the inner diameter of the distal end spatula portion. The vertebral body processing tool is rod-shaped and has a curved portion that curves downward along the central axis; when the foregoing is inserted into the vertebral body perforation guide from the terminus portion along the central axis and has passed the intermediate portion along the central axis, the distal end protrudes out from the opening of the distal end spatula portion. Provided is a safe therapeutic instrument that, in percutaneous vertebroplasty for a fracture or surgery to preventatively reinforce a vertebral body with bone cement, makes it possible to accurately excavate an intended location to every corner within the vertebral body while also minimizing incision in the skin.

The present invention provides a device for automatically incising the skin during surgery, a control method thereof, and an electronic device. The device includes a robotic arm end, the robotic arm end includes a six-dimensional force sensor and a head tracker, the robotic arm end is installed with a flange, the six-dimensional force sensor is installed on the flange, the head tracker is arranged at the end of the six-dimensional force sensor, and a skin cutting tool is installed at the end of the head tracker for incising the skin; a robotic arm controller is used to control the skin cutting tool to incise the skin, by controlling the cutter head of the skin cutting tool at the end of the robotic arm to penetrate the skin to a first preset depth at a preset position according to a first expected control force; controlling the cutter head to cut a first preset length along a preset direction according to a second expected control force; after the cutting is completed, controlling the cutter head to move upward away from the skin incision, thereby realizing the function of automatically incising the skin, greatly reducing the skin incision error caused by human factors, and further improving the success rate of the operation.

The present invention relates to a medical device, specifically to a subcutaneous tunneler assembly for artificial vascular arteriovenous fistulas, which includes a dilator, a guidewire, and a sleeve. The dilators are two open-ended, tubular structures, each with a bendable segment. The sleeve has a sleeve cavity that fits the artificial vascular graft. The guidewire is placed in the communicating cavity formed by the abutment of the two dilators. The bendable segments bend the two dilators to fit a predetermined path of the subcutaneous tunnel. After the dilators are introduced subcutaneously through a skin incision, the ends are abutted to form a continuously curved U-shaped subcutaneous tunnel, reducing the size of the skin incision, minimizing surgical trauma, and preventing infection. The sleeve protects the artificial vascular graft from contact with the skin, reducing the risk of infection during surgery. After the artificial vascular graft is inserted into the sleeve, there is no need to adjust its position, preventing twisting, bending, or bending of the artificial vascular graft during insertion.

FIELD: traumatology; orthopedics.SUBSTANCE: used for arthroscopy of the hip joint to eliminate Cam or combined types of femoroacetabular impingement. A proximal anterolateral port is created to the peripheral portion of the hip joint, which is used as a viewing port at the beginning of the operation; 4 cm distal and 2 cm lateral to the intersection of the midline of the femur and the perpendicular drawn to it through the apex of the greater trochanter, an anterior port is created, which is used as an instrumental port at the beginning of the operation. The deformation zone is brought to the bone burr, changing the positions of flexion and extension, internal and external rotation of the lower limb, and until the appearance of spring resistance of the fibers of the lateral joint capsule and the ileofemoral ligament, resection of excess bone mass of the anterior surface of the proximal femur within the boundaries of the Cam-deformation is performed. The viewing and instrument ports are changed and the deep fibers of the proximal joint capsule and the ileofemoral ligament are released from the acetabulum. In the presence of Pincer deformity, soft tissues are removed to visualize excess bone mass within the boundaries of the Pincer deformity, and resection of excess bone mass of the anterolateral edge of the acetabulum within the boundaries of the Pincer deformity is performed until radiographic visualization of the absence of intersection of the anterior and posterior edges of the acetabulum. The viewing and instrument ports are replaced. An arthroscope is positioned on the outer edge of the joint capsule fibers, and bone resection of the posterolateral surface of the proximal femur is completed within the boundaries of the Cam deformity by inserting a bone burr from the skin incision of the anterior port into the capsule opening of the proximal anterolateral port, preserving the fibers of the joint capsule and the ileofemoral ligament.EFFECT: method ensures correction of the proximal femur within the boundaries of the Cam-deformation while maintaining the integrity of the structures of the passive capsular-ligamentous stabilizers and eliminates the development of complications in the form of microinstability of the hip joint, anterior dislocation of the femoral head, heterotopic ossification due to maintaining the integrity of the structures of the passive capsular-ligamentous stabilizers and eliminating the development of microinstability of the hip joint, anterior dislocation of the femoral head and heterotopic ossification.1 cl, 1 ex

The utility model discloses a kind of suture devices facilitating to adjust suture force, belong to suture device technical field, the suture device facilitating to adjust suture force, including easy tear film, easy tear film top end one side is fixedly installed with first hydrocolloid composite film, easy tear film top end other side is fixedly installed with second hydrocolloid composite film, the one side of first hydrocolloid composite film and second hydrocolloid composite film is fixedly installed with tear and pull section, the top of first hydrocolloid composite film and second hydrocolloid composite film is provided with suture mechanism, the inside of suture mechanism is provided with adjusting mechanism. The utility model is equipped with suture mechanism and adjusting mechanism, so that medical staff in operation process, can directly adjust from the side of skin incision, without like traditional method respectively from the adjustment of two sides of wound, greatly reduce operation time and difficulty, especially in emergency medical situation or the scene needing to handle wound quickly, can significantly improve suture efficiency.

Disclosed herein are embodiments of a system for stabilizing spinal vertebrae through a skin incision, that include a first extension (410) removably coupled with a first screw (402) at a distal end thereof, and a second extension (420) removably coupled with a second screw (404) at a distal end of the second extension. A first opening (432) extends through a wall of the first extension. Further, the first opening and the wall of the first extension adjacent to the first opening is sized and configured such that the second extension can be advanced through the first opening so that the second extension is restrained within the first opening and is positionable at an acute angle relative to an axial centerline (C) of the first extension.

The present invention provides a linear minimally invasive wrinkle removal dissector with an equal perimeter of the head and rod part, which is composed of a dissection head, a connecting rod and a handle. The dissection head and the connecting rod are integrally connected, and the connecting rod and the handle are connected by threads. The maximum perimeter of the flat dissection head is equal to or approximately equal to the perimeter of the cylindrical connecting rod, so that a skin incision with the same diameter as the connecting rod of the dissector can accommodate the dissection head. Compared with the existing dissector with a large head and a thin rod, it can minimize the skin incision to the greatest extent, and the skin at the incision can better fix the dissector, limit the swing of the connecting rod, and make the subcutaneous tunnel formed by dissection more accurate. The dissection head and the connecting rod are made of bendable metal materials, which can be appropriately bent during the operation according to actual needs to better adapt to the facial contour and reduce unnecessary tissue damage during the dissection process. The handle has an anti-slip design, which is more suitable for grasping by hand, increasing the stability of grasping and improving the comfort of the doctor's operation.

The utility model discloses a forehead soft tissue tumor resection endoscope cannula, which comprises a puncture cannula, the front end of the puncture cannula is provided with a spreader, the rear end of the puncture cannula is provided with an incision protection plate, and the incision protection plate and the axis of the puncture cannula form an included angle of 60 degrees. The dilator end of the endoscopic cannula is inserted into a skin incision, the front end of the puncture cannula is pushed to a to-be-cut tumor site, the puncture cannula is provided with a hollow instrument channel, the instrument channel is communicated with the front end of the puncture tube and the incision protection plate, and when the front end of the puncture cannula reaches the to-be-cut tumor site, the incision protection plate is adjusted to be parallel to the forehead face in the tangential direction, and the incision protection plate is pushed to the to-be-cut tumor site. The effect of protecting the skin incision is achieved. Meanwhile, surgical instruments such as an endoscope can be conveyed to the site where the tumor is to be cut through the instrument channel for surgical operation. The incision protection plate of the endoscope cannula can be effectively attached to the frontal face hairline position, an incision is effectively protected, and therefore implementation of a follow-up endoscope operation is more convenient, and the problems existing in the prior art are effectively solved.

The present application provides a kind of gastric laparoscopic surgery puncture device with anti-skid fixing function, overcome the traditional puncture device cannot be punctured into stomach cavity, stomach cavity cannot be close to abdominal wall after puncture, gastric contents easily reflux into abdominal cavity through puncture device and cause pollution etc. Surgical difficulties, this puncture device makes this new technology surgical procedure more simplified, safe and effective. Including sleeve assembly and puncture assembly, sleeve assembly includes sleeve seat and sleeve arranged at one end of sleeve seat, puncture assembly includes puncture handle and puncture needle arranged at one end of puncture handle, and puncture needle is slidably arranged in sleeve. The present application can effectively avoid the phenomenon that sleeve slides out from stomach cavity, repeatedly punctures and damages stomach and other organs and blood vessels of patient, avoid pulling out the whole puncture device when pulling out the equipment, ensure that gastric laparoscopic surgery is carried out smoothly, reduce the pain of patient;Simple structure, convenient operation, save time and effort, improve the protection and fixing effect of sleeve and surgical efficiency;Can pull the skin incision, improve the fixing effect.

The clinical skin incision positioning device comprises a lower positioning supporting frame, the lower positioning supporting frame is composed of a positioning main supporting body and end plates, the end plates are arranged at the two opposite ends of the positioning main supporting body, and connecting supports are arranged at the two opposite ends of the positioning main supporting body; a sliding guide rail shaft is arranged above the positioning main supporting body through two connecting supports, a skin incision cutter is arranged on the sliding guide rail shaft between the two connecting supports in a sliding mode through a fixator mechanism, and limiting mechanisms are arranged on the sliding guide rail shafts on the two opposite sides of the fixator mechanism. And a flattening mechanism is adjustably arranged on the skin incision cutter. A series of structures are arranged, the positioning and supporting direction can be adjusted according to the requirement of a surgical incision, the skin incision is accurately and flexibly positioned, the applicability is high, and the skin incision cutter can move and rotate up and down through the fixator mechanism; the flattening mechanism flattens and positions the upper portion of the skin, and surgical operation is facilitated.

The invention provides a tool bit and a skin cutting device, and belongs to the technical field of medical equipment.The tool bit comprises a tool bit body, a cover plate and a tool handle, the tool bit body is in a thin-wall barrel shape, one end of the tool bit is arranged to be a tool edge, and the tool bit body linearly shrinks from the end provided with the tool edge to the other end; the cover plate covers the end, away from the knife edge, of the knife head body, and an exhaust port is formed in the cover plate. The cutter handle is arranged on the side, away from the cutter head body, of the cover plate. The knife head and the skin cutting device provided by the invention are beneficial to formation of a skin edge slight eversion upheaval state in a skin suturing process, are convenient to carry out embedded mattress type subcutaneous suturing, form a state that an incision forms a section slight outward inclination state from a body surface to a dermis direction, are beneficial to beauty healing of the skin incision, improve the operation precision of skin biopsy, and improve the operation efficiency of the skin biopsy. And the benign healing rate and the beauty healing rate of the incision are improved.

This invention provides embodiments and methods of a system for stabilizing the vertebrae through a skin incision. [Solution] In some embodiments, the system or method may comprise a first screw 2202 having a first screw head, a second screw 2204 having a second screw head, a third screw 2206 having a third screw head, a first tower 2212 having a distal portion, a proximal portion, and a bend between the distal and proximal portions, a second tower 2214 having a distal portion and a proximal portion, the second tower being configured to be removably coupled to the second screw at the distal end of the second tower, and a third tower 2216 having a distal portion, a proximal portion, and a bend between the distal and proximal portions.

The invention provides a high-performance supramolecular hydrogel for hemostasis and wound closure and a preparation method thereof. The preparation method comprises the following steps: synthesizing a monomer 4-(6-(3-(6-methyl-4-oxy-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl)-1, 2, 4-triazole-4-yl the monomer is 2-(2, 4-dihydropyrimidine-2-yl) ureido) hexylcarbamoyloxy)-ethyl acrylate, the monomer is composed of an acrylic acid head, a hydrophobic alkyl spacer connected with carbamate and a self-complementary 2-2-ureido-4-pyrimidone motif, and hydrophobic association and quadruple hydrogen bonds are generated; under the condition that an emulsifier and a chemical cross-linking agent are not used, initiating monomer copolymerization through a photoinitiator, and introducing epigallocatechin gallate, so as to obtain the supramolecular hydrogel. The supramolecular hydrogel disclosed by the invention shows the properties of high strength, high toughness, high elasticity and the like, and shows excellent hemostasis and wound closure capabilities in rat liver puncture and incision models and full-thickness skin incision models.

Minimally invasive histotripsy systems and methods are provided. In some embodiments, a minimally invasive histotripsy device is inserted into a patient. The device can be inserted endoscopically through a natural orifice of the patient, or laparoscopically through an incision in the patient's skin. The minimally invasive histotripsy device can be advanced to the target tissue and acoustically coupled to the target tissue before applying histotripsy therapy to the target tissue. In some embodiments, the minimally invasive histotripsy device includes a transducer array with a focal length of approximately 10-40 mm, a diameter of less than 35 mm, and the ability to create a peak negative focal pressure of at least 20 MPa.

The invention belongs to the technical field of medical instruments, and particularly relates to a skin incision tissue retraction dilator which comprises skin attaching equipment. The control equipment is arranged outside the skin attaching equipment, and the adjacent control equipment is clamped through a connecting assembly; the side traction equipment is arranged on the outer surface of the control equipment; the control device comprises an upper pasting plate, and the inner wall of the upper pasting plate is in sliding connection with the outer surface of the skin pasting device. Due to the fact that the skin attaching equipment moves through the control roll shaft of the upper attaching plate, the size of an incision can be accurately expanded, when the incision of a patient suffers from massive hemorrhage or an accident, the skin attaching equipment on the two sides can rapidly push a plate body at the front end traction incision part through the corresponding rear air box, and therefore the effect of closing the incision is achieved, and the patient can conveniently and rapidly take off the incision. And the incision of the patient is wrapped by the sheet plates at the front end and the rear end, so that the incision of the patient is prevented from further deteriorating, and an effective emergency function is achieved.