Provided herein is a computer-implemented method including obtaining values for non-modifiable risk factors, each defining an immutable patient characteristic determined to
impact a likelihood that a complication results from an
arthroplasty procedure. The
system obtains first candidate values for modifiable risk factors of the patient defining a mutable characteristic of the patient or the
arthroplasty procedure. The first candidate values are determined to minimize the likelihood that the complication results from the
arthroplasty procedure. The
system obtains second candidate values for the modifiable risk factors of the patient determined to maximize the likelihood that the complication results from the arthroplasty procedure. The
system determines a personalized risk interval that represents a range of modifiable risk for the patient with respect to the arthroplasty procedure including determining (i) a lower bound and (ii) an upper bound for the personalized risk interval; and providing an output indicative of the risk interval.