The invention provides an acetabulum side guide plate assembly for hip joint replacement and an assembling method of the acetabulum side guide plate assembly. The acetabulum side guide plate assembly for hip joint replacement comprises a fitting guide plate, a supporting rod, a surgical instrument supporting piece and a positioning nail. The fitting guide plate comprises an attaching base, a guide rod and a positioning connecting piece, the attaching base is suitable for being attached and matched with the acetabular fossa of the human body, and the guide rod extends from the top face of the attaching base in the radial direction of the attaching base; the supporting rod is suitable for being matched with the positioning connecting piece for positioning and is suitable for being separated from the positioning connecting piece; and the positioning nail is suitable for fixing the supporting rod to the outer area of an acetabular fossa, the surgical instrument supporting piece is suitable for being fixed to the supporting rod in a matched mode, and the surgical instrument supporting piece is arranged to be capable of being matched with the supporting rod for positioning and detachably connected with the supporting rod. According to the acetabular side guide plate assembly for hip joint replacement and the assembling method of the acetabulum side guide plate assembly, it can be guaranteed that an acetabular cup prosthesis can be accurately placed, the operation precision is improved, the ideal operation effect is achieved, and the occurrence rate of postoperative complications is reduced.