15 results about "Burning Sensation" patented technology

The invention relates to a pharmaceutical composition, which is prepared from adapalene, benzoyl peroxide, a traditional Chinese medicine extract, an acrylamide and acryloyl dimethyl sodium taurate copolymer, a mixture of isohexadecane and polysorbate 80, docusate sodium, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, glycerol, poloxamer 124, propylene glycol and water, the traditional Chinese medicine extract comprises moutan bark, salvia miltiorrhiza, radix rehmanniae recen, radix sophorae flavescentis, coptis chinensis, rheum officinale, scutellaria baicalensis, menthol and borneol. According to the pharmaceutical composition disclosed by the invention, the synergistic antibacterial and anti-keratosis curative effects of adapalene and benzoyl peroxide can be maintained, and meanwhile, the occurrence rate of local skin dryness, erythema, desquamation, burning heat sensation and contact dermatitis can be remarkably reduced.

This invention relates to the field of skincare essential oil technology, and more particularly to a soothing and repairing essential oil containing peony seed oil and chrysanthemum essential oil, and its preparation method. It is made from the following raw materials in parts by weight: 50-90 parts olive oil; 0.3-25 parts peony seed oil; 0.1-8 parts chrysanthemum essential oil; and 0.1-2 parts vitamin E. Chrysanthemum essential oil has a high content of camphor and borneol, resulting in stronger transdermal penetration and antibacterial capabilities, but it also causes irritation. This invention reduces the irritation rate by incorporating peony seed oil. Peony seed oil is rich in linoleic acid, whose molecular structure is highly similar to the lipids of the skin barrier. The terpenoid components in chrysanthemum essential oil can be encapsulated by linoleic acid micelles, avoiding the burning sensation caused by the instantaneous contact of high-concentration chrysanthemum essential oil with the skin, and making it easier to penetrate the stratum corneum.

The invention discloses a traditional Chinese medicine composition for treating perimenopausal dry eyes and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine formulas. The traditional Chinese medicine composition for treating the perimenopausal dry eye comprises herba epimedii, prepared rehmannia root, rhizoma anemarrhenae, cortex phellodendri, radix paeoniae alba, angelica sinensis, radix bupleuri, poria cocos and honey-fried licorice root. The traditional Chinese medicine composition for treating perimenopausal dry eye, namely the kidney-warming dry eye formula, has the functions of warming kidney, nourishing yin, soothing liver and strengthening spleen, can effectively improve perimenopausal symptoms such as dry eye, photophobia, asthenopia, foreign body sensation, burning sensation, soreness and weakness of waist and knees, dysphoria, irritability, hot sweating, insomnia, amnesia and the like of patients with perimenopausal dry eye, improves the estrogen level, and has the efficacy of treating perimenopausal dry eye. The ocular surface inflammatory response is inhibited, and the tear film stability is improved.

The invention discloses scald ointment with a superstrong healing function, and relates to the field of scald ointment. According to the scald ointment with the super-strong healing function, the honey can keep a wound moist, reduce pain and prevent infection; the garden burnet has the effects of astringing to stop bleeding, diminishing inflammation and detoxifying, and can relieve edema, relieve pain and promote granulation tissue growth when being used for scalds; the radix arnebiae seu lithospermi has the effects of clearing away heat and toxic materials and cooling and activating blood and can promote cell regeneration, diminish inflammation and repair damaged skin; the coptis chinensis has relatively strong antibacterial and anti-inflammatory effects and is suitable for preventing and controlling scald infection; scutellaria baicalensis has the effects of clearing heat, drying dampness, purging fire and removing toxin, and is cooperated with coptis chinensis to enhance the antibacterial and anti-inflammatory effects and relieve the heat toxin symptom caused by scald; borneolum syntheticum has the effects of cooling, relieving pain and diminishing inflammation, can immediately relieve pain and burning heat caused by scald, and promotes transdermal absorption of the medicine; all the components interact to remarkably improve the healing speed of the wound surface, and the formula adopts natural components and is small in side effect and rapid in comprehensive effect.

A contact lens having an amount of at least one cooling agent and at least one TRPV1 inhibitor releasably adhered is described as well as method of manufacturing the same. The contact lens can be comfortably worn by contact lens wearers and can increase the duration of comfortable lens wearing time and / or reduce lens awareness events and / or reduce contact lens dryness in a symptomatic contact lens wearer and further can reduce or avoid any stinging / burning sensation when the contact lens is first used or a short time thereafter.

The present invention relates to a pest repellent composition which, when applied to the skin, provides a superior long-lasting repellent effect while imparting a favorable cooling sensation without causing unpleasant irritation or a burning sensation.　Specifically, the present invention provides a pest repellent composition comprising the following components (A) to (C): (A) 13 mass% or more and 50 mass% or less of one or more non-volatile liquid oils selected from silicone oils, ester oils, ether oils, hydrocarbon oils, aliphatic alcohols, and polyhydric alcohols; (B) hydrophilic fine particles containing silica particles and / or silicate particles and having a volume median particle diameter of 1 μm to 40 μm inclusive; and (C) menthol. The mass ratio ((C) / (A)) of the content of component (C) to the content of component (A) is 0.0008 to 0.45 inclusive.

The application provides a light-guiding gel and a production process thereof. The light-guiding gel is prepared from the following raw materials in percentage by mass: 0.3-0.4% of carbomer, 0.08-0.12% of polylactic acid-glycolic acid copolymer, 1.4-1.6% of shea butter, 4.5-5.5% of glycerol, 0.1-0.2% of preservative, 0.3-0.35% of triethanolamine, 1.6-2.2% of MIST BASE (HIGH), 0.008-0.012% of essence and the balance of purified water. The light-guiding gel prepared by the application has super light transmission and heat conduction properties and good biological safety. The application not only effectively improves the treatment effect, but also greatly relieves the burning sensation of the skin, avoids thermal damage, greatly reduces the discomfort, and is beneficial to the skin barrier repair.

The embodiment of the invention provides a buccal product and a preparation method thereof.The buccal product provided by the embodiment of the invention comprises at least two liquid permeable layers, at least two functional layers and at least two bearing layers, and the buccal product is symmetrically arranged about a first plane in the first direction; wherein the two sides of the first plane are each provided with a liquid permeable layer, a functional layer and a bearing layer, and the functional layers are provided with flavor substances and / or active substances; the liquid-permeable layer, the functional layer and the bearing layer are symmetrically arranged along the first plane, convenient manufacturing in a folding mode is facilitated, the existence of the liquid-permeable layer not only can relieve the stimulation feeling of an oral cavity when soluble substances are used, but also enables the buccal product to easily move and release the position and avoid over-stimulation, and the liquid-permeable layer has a water locking function and can lock part of saliva, so that the oral product is convenient to use. Spicy throat and stomach burning heat are relieved, and therefore the use experience of a user is improved.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for treating rosacea, its preparation method, and its application. This invention provides a traditional Chinese medicine composition for treating rosacea, comprising dandelion, purslane, sophora flavescens, sophora japonica flower, and rhubarb. The traditional Chinese medicine composition of this invention has the effects of clearing heat and detoxifying, reducing inflammation and antibacterial properties, cooling blood and promoting blood circulation, and repairing the skin barrier. It can be used to treat erythematous rosacea, relieving erythema, telangiectasia, papules, itching, and burning sensation on the skin, and reducing the risk of recurrence.

This invention belongs to the field of daily chemical products and discloses a composition for synergistic regulation of dual-pathway temperature sensation and its application, comprising ginger root extract and plant oil; the ginger root extract is obtained by extracting ginger root through carbonic acid nanobubbles; the plant oil has the function of inhibiting the overactivation of skin temperature receptors and reducing the stinging or burning sensation caused by ginger root extract. This composition, by combining ginger root extract extracted through carbonic acid nanobubbles with plant oil that inhibits the overactivation of skin temperature receptors, can achieve a sustained and effective temperature sensation, lasting for more than 15 minutes, and exerted in a gentle temperature sensation.

The invention relates to the field of tobacco, in particular to a nicotine product and a preparation method thereof. The nicotine product is prepared from the following components in parts by mass: 0.1 to 0.3 part of taste improving composition, 50 to 90 parts of glycosyl, 0.1 to 1 part of nicotine salt, 0.1 to 10 parts of essence and perfume and 0.1 to 5 parts of auxiliary materials. By adding the taste improving composition, the nicotine product is mild and smooth in mouth, burning feeling and strong throat irritation caused by free alkali nicotine are greatly reduced, user experience is better and easier to accept, and flavor and taste are fuller. Meanwhile, the toothpaste is more convenient to use, does not need to be placed at positions such as gingival roots, is convenient to store, and is free of residues and pollution after being eaten.

The present application is about the non-therapeutic use of 1,4:3,6-dianhydrohexitols, preferably isosorbide, as a soothing agent in cosmetic compositions. Isosorbide is able to reduce or eliminate at least one non-pathological physical sensation chosen from burning sensations, warmth, tightness, tingling, numbness and / or itching, said sensation occurring on the skin and / or on the oral mucosa. Isosorbide may be applied as a cosmetic care to alleviate these non-pathological sensations either before, during or after their occurrence, as a dedicated care or inside a cosmetic product containing factors of chemical aggression, such as surfactant or organic acids.

The invention relates to the technical field of ophthalmic medicine preparations, in particular to artificial tear simulating a tear film multilayer structure and preparation and application thereof. The artificial tear provided by the invention is prepared from the following components in percentage by mass: 3.0 to 10.0 percent of a structure simulation agent, 0 to 8.0 percent of grease, 0.5 to 2.0 percent of an auxiliary agent and 80.0 to 96.5 percent of PBS (Phosphate Buffer Solution). According to the artificial tear provided by the invention, by simulating the functions of a lipid layer, a water layer and a mucus layer of a tear film, the eye condition is improved from multiple dimensions, the hydrophobic part prevents evaporation and can reduce tear loss and relieve dryness, the hydrophilic part simulates the water layer to supplement moisture, and the synergistic effect of the hydrophilic and hydrophobic structures can repair the integrity of the tear film and prolong the stabilizing time of the tear film; the lubricating effect of interlayer slippage directly relieves discomfort such as foreign body sensation and burning sensation caused by eye friction, and finally relieving of the dry eye symptom, repairing of a tear film structure and long-term maintaining of the wet and lubricating state of the eye surface are achieved.

The application belongs to the field of cosmetics and discloses a composition for relieving skin thermal aging stress. The composition for relieving skin thermal aging stress comprises, in parts by mass, 2-12 parts of silk fibroin, and 10-65 parts of a relieving ferment, wherein the relieving ferment is a combination of eucommia ulmoides, peach resin, cactus and dendrobium, and the mass ratio of eucommia ulmoides, peach resin, cactus and dendrobium is 3-4:3-5:2-3:2-3. The composition provided by the application can improve cell heat shock protection, restore normal expression of proteome induced by thermal stress, and improve sensitive symptoms such as skin photoaging, redness and burning sensation.

The present invention relates to a 5-aminolevulinic acid derivative having improved storage stability and bioavailability, and a pharmaceutical composition comprising the same, the present invention exhibits a pharmacokinetic profile in which 5-aminolevulinic acid is more effectively exposed to blood in vivo, and reduces side effects after treatment, such as pain, erythema, swelling, edema, burning sensation, pruritus, spalling, hyperpigmentation and long-term stimulation and hypersensitivity. Further, the present invention relates to a 5-aminolevulinic acid derivative and a composition comprising the same, in which 5-aminolevulinic acid exhibits high efficiency while reducing the severity of side effects, and the 5-aminolevulinic acid derivative and the composition comprising the same are useful for photodynamic diagnosis and therapy.