13results about How to "Targeted" patented technology

This invention provides a method and apparatus for vehicle-mounted audio zone noise reduction, relating to the field of vehicle control technology. The method includes: when any target occupant among multiple occupants in a vehicle is in a call state, determining the target seat area where the target occupant is located from multiple seat areas in the vehicle; determining an acoustic control area based on the target seat area; when there is playback content in the acoustic control area, reducing the playback volume of the playback device in the acoustic control area; and when it is detected that the target occupant's call has ended, restoring the playback volume of the playback device in the acoustic control area to its original volume.

A hinge cup for metal hinges includes a panel and a recessed pocket portion located in the middle of the panel. A hinge seat for hinged connection with the hinge body is provided on one side of the panel and pocket. Several outwardly protruding anti-detachment devices are integrally formed on the outer cylindrical surface of the pocket, serving to engage with the inner wall of the mounting holes after the hinge cup is installed into the plate. The beneficial effects of this invention are: the anti-detachment devices effectively resist external axial pull-out forces and radial wobbling, directly enhancing the bonding force between the hinge cup and the plate, fundamentally improving the anti-detachment performance of the hinge cup, and significantly enhancing the locking force.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for treating rosacea, its preparation method, and its application. This invention provides a traditional Chinese medicine composition for treating rosacea, comprising dandelion, purslane, sophora flavescens, sophora japonica flower, and rhubarb. The traditional Chinese medicine composition of this invention has the effects of clearing heat and detoxifying, reducing inflammation and antibacterial properties, cooling blood and promoting blood circulation, and repairing the skin barrier. It can be used to treat erythematous rosacea, relieving erythema, telangiectasia, papules, itching, and burning sensation on the skin, and reducing the risk of recurrence.

This invention discloses a nystatin microsphere with targeted enhanced antifungal function, its preparation method, and its application. The microsphere uses sodium alginate as a carrier, internally encapsulating the antifungal drug nystatin. The surface is covalently modified with the β-glucan binding domain of the Dectin-1 protein, constructing a smart drug delivery system with fungal targeting function. The microsphere preparation process is simple and reproducible, and can be scalable using an emulsion-ionic crosslinking method combined with protein coupling technology. In vitro characterization shows that the microspheres have uniform particle size and stable dispersion, and Dectin-1 modification significantly enhances their specific binding ability against Candida albicans. This targeted delivery system, while successfully preserving drug activity, significantly improves the antifungal efficiency of nystatin through Dectin-1-mediated targeting, achieving efficacy close to that of free drug, and providing a new strategy for constructing highly efficient and long-acting antifungal agents.

The application discloses a multi-axis hole robot assembly method based on abnormality identification and retreat reconstruction, and relates to the technical field of robot precision assembly and intelligent manufacturing. The method comprises the following steps: in the process of inserting and assembling the robot based on the pre-alignment result, a contact feature vector is extracted from an assembly process observation vector; the values of all elements in the contact feature vector are weighted and summed to obtain a contact abnormality discrimination index; when the contact abnormality discrimination index is greater than or equal to a preset abnormality threshold, the retreat direction and retreat distance of the robot are determined based on the contact abnormality discrimination index and the contact feature vector, and a retreat action is performed; a re-alignment control quantity and a re-insertion reference path parameter used for recovering assembly are generated; and the robot is controlled to perform recovery assembly according to the re-alignment control quantity and the re-insertion reference path parameter until the assembly is completed or an abnormality recovery termination condition is reached. The method improves the overall success rate of the assembly process.

This invention relates to an integrated system, method, and unmanned aerial vehicle (UAV) system for early warning, sampling, and replenishment of bioaerosols. The controller activates a microbial early warning device to allow air to enter. The device samples airborne microorganisms, generating fluorescent signals. The controller analyzes these fluorescent signals to determine if the aerosol concentration exceeds a preset value or if microbial aerosols are detected. If so, the controller activates the microbial early warning device and simultaneously starts the microbial sampling and replenishment device. A sampling liquid pump injects the sampling liquid into the sampler, and a fan then circulates air into the sampler for sampling. During sampling, a temperature and humidity sensor monitors the ambient temperature and humidity in real time every second. The controller uses this data to calculate the evaporation rate of the sampling liquid (evaporation rate per second = replenishment rate per second) using a fitting function. The controller then controls the sampling liquid pump to operate for the calculated time, injecting the sampling liquid into the sampler for real-time sampling and replenishment. Once the preset sampling time is reached, the controller activates the sample pump to inject the sample liquid from the sampler into a sample bottle.

This invention belongs to the field of flexible body aircraft technology, specifically disclosing a method for measuring the stiffness of a flexible wing. This method is based on a static strength and stiffness measurement platform for flexible wings, which includes a test bench support frame, a specimen fixing platform, support rods, tension ropes, a rangefinder, and a counterweight loading component. The stiffness measurement method includes: calculating the test load; installing the flexible wing test specimen; marking the flexible wing test specimen; designing and preparing the counterweight loading component; applying equivalent loading under the test condition; measuring the bending and torsional stiffness boundaries; and post-processing the measurement results. This measurement method significantly improves loading accuracy and can simulate loads under bending, torsion, or combined bending and torsion conditions of flexible wings to obtain stiffness and instability boundaries. It overcomes the shortcomings of traditional flexible wing structural stiffness measurement methods, which can only perform rough loading and cannot handle heavy loads, and can measure the load-bearing capacity and stiffness of high aspect ratio, high load-bearing special-purpose flexible wings.

This invention relates to agricultural biological control technology, aiming to provide a bamectin-degrading strain, Ldeb-1, and its application in enhancing the resistance of parasitic wasps. This strain is deposited at the China Center for Type Culture Collection (CCTCC), with the deposit name *Stenotrophomoans maltophilia* Ldeb-1 and the Latin taxonomic name *Stenotrophomoans maltophilia*, and the accession number CCTCC NO: M 20252462. The 16S rRNA gene sequence of the strain is shown in SEQ ID NO: 1. This invention provides a novel strain with outstanding degradation activity against the next-generation macrolide insecticide bamectin, offering a highly targeted and precise tool for addressing bamectin pesticide residue problems. Introducing a strain derived from a specific parasitic wasp species into its own species can enhance the parasitic wasps' intrinsic resistance to bamectin, representing a green, safe, and sustainable technology.

The application is suitable for the field of biological medicine technology, and provides a preparation method and application of CAR-T cells loaded with biological calcified nanomaterials, which comprises the following steps: step one, mixing black phosphorus quantum dots, calcium peroxide and lipid components, and purifying by ultrasonic emulsification and ultrafiltration centrifugation to obtain BCLT with mitochondria-targeting molecule triphenylphosphine modified on the surface; step two, co-incubating CAR-T cells with membrane dye after staining, and adding a disulfide bond-containing reduction-responsive linker arm DSPE-S-S-NHS; and step three, co-incubating BCLT with CAR-T cells, so that the BCLT is connected to the surface of the CAR-T cells through a chemical bond to obtain CAR-T cells loaded with biological calcified nanomaterials. The application significantly improves the infiltration capacity and killing effect of the CAR-T cells on solid tumors, can relieve the problem of tumor heterogeneity, and has excellent biological safety and synergistic anti-tumor effect.

This invention discloses a pathogenic gene, protein, and application of *Verticillium dahliae*. This invention relates to the field of biotechnology and provides a method for controlling *Verticillium dahliae* wilt based on RNAi (RNA interference), along with its related components and applications. Specifically, it discloses the method of inhibiting or silencing the pathogenic gene of *Verticillium dahliae*. VdHDAC The application of the expression method (whose encoded protein is shown in SEQ ID NO:3) for the prevention and control of Verticillium wilt relies on providing a class of dsRNA molecules that can target this gene, with the positive strand preferably selected from SEQ ID NO:5, SEQ ID NO:8, SEQ ID NO:9, or SEQ ID NO:11. Based on this molecule, this invention further provides recombinant vectors containing its coding sequence, recombinant microorganisms, transgenic disease-resistant plants, and RNAi pesticide formulations. These methods can be achieved through host-induced gene silencing, microorganism-mediated gene silencing, or formulation treatment, effectively reducing the virulence of the pathogen and providing a new technical approach for the green control of Verticillium wilt.

This invention discloses a control method and a garment processing device. The control method includes: after washing, starting a timer and acquiring condition parameters in real time, including the ambient temperature around the garment processing device and the turbidity of the residual water in the drain pipe; if the ambient temperature and turbidity meet the residual water replacement conditions, executing a residual water replacement program at set intervals; the residual water replacement program includes an inlet process and a drain process to replace the residual water in the drain pipe. The garment processing device includes a drain pipe and uses the above-described control method to treat the residual water in the drain pipe. By combining the two parameters of ambient temperature and turbidity, the residual water in the drain pipe is replaced through a residual water replacement program, which is more targeted, avoids water waste and bacterial growth and odor in the residual water, and prevents the residual water from affecting the clothes.

This invention specifically discloses an ACVR2A antibody and its applications, relating to the field of biomedical technology. The antibody provided by this invention has a stronger affinity for and higher selectivity for ACVR2A, offering diverse treatment options for different clinical needs and expanding the application potential of ACVR2A-targeted therapy.

This invention relates to the field of computer vision technology, and provides a standard judgment method and scoring device for basic human motor skills. The method includes: recording relevant information of key points of the human body; identifying the person with the smallest change in human body indicator features in two adjacent frames as the same person; recording the position information of the target object; processing the relevant information of the key points and the position information of the target object to obtain action detail information; comparing and analyzing the action detail information with the detail requirements, and synchronously displaying the preliminary evaluation results on the image; after completing the processing and analysis of all frames of the video, obtaining the final evaluation result corresponding to each detail requirement; the evaluation result of the action standard is derived from the final evaluation result of the corresponding detail requirement through a bitwise AND operation; this invention improves the accuracy of scoring by breaking down each action standard into different detail requirements; and makes sports training more targeted and scientific by judging human movements in real time.